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The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 10 | Pages 1379 - 1381
1 Oct 2007
Sandher DS Al-Jibury M Paton RW Ormerod LP

We report 79 cases of bone and joint tuberculosis between 1988 and 2005, eight of which were in the Caucasian population and 71 in the non-white population.

The diagnosis was made in the majority (73.4%) by positive bacteriology and/or histology. The mean age at the time of diagnosis was higher in the Caucasian group at 51.5 years (28 to 66) than in the South Asian group at 36.85 years (12 to 93). Only one patient had previous BCG immunisation.

The spine was the site most commonly affected (44.3%). Surgical stabilisation and/or decompression was performed in 23% of these cases because of cord compression on imaging or the presence of neurological signs.

A six-month course of chemotherapy comprising of an initial two months of rifampicin, isoniazide, pyrazinamide and sometimes ethambutol followed by four months treatment with rifampicin and isoniazide, was successful in all cases without proven drug resistance.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_II | Pages 105 - 105
1 Feb 2003
Sandher DS Chambers IR Gregg PJ
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We have performed a study comparing the radiological results of Total hip replacements performed by a single, experienced specialist hip surgeon with those reported from the Trent Regional Arthroplasty Study (TRAS) [presented at BOA congress 2000]. Results from TRAS have revealed that inadequate cementation grades and a cement mantle width of < 2mm were the most significant associations predicting early aseptic loosening. Interestingly, their respective incidences were as large as 20% and 50% in a random sample of THRs from the TRAS register.

Data is lacking as to whether poorer radiographic cementation grades have a trend towards individual surgeons or whether they are more evenly distributed amongst the surgical population including those adhering to modem techniques.

Therefore, we have undertaken an independent review of A-P and lateral radiographs of 33 consecutive Charnley THRs performed by a specialist hip surgeon using carefully controlled modem cementing techniques and compared the results with the same random cohort of THRs from the TRAS.

Our results show that the specialist surgeon achieved a significantly higher proportion (82%) of complete cement mantles (> 2mm in all zones) than those achieved by TRAS (50%) [Chi2=7. 79, p=0. 0052]. This suggests that improved cement mantles can be achieved by the adoption of carefully controlled modem cementing techniques. However, use of the Barrack system of grading was unable to detect differences in cementation quality between specialist (88%) and TRAS group (81%) [Chi2=0. 235; p=0. 631 suggesting less sensitivity in this technique for assessing cementation quality. These results are important for the following reasons. Achievement of adequate mantle (> 2mm) can be improved upon by adoption of carefully controlled modem cementing technique. However, regardless of the method of assessment of cementation quality, approximately 18% will appear ‘inadequate’ despite modern techniques suggesting that factors outside the surgeon’s control are involved in determining cementation grade. This has important medico-legal implication in the current climate in which surgeons are being criticised, in negligence cases arising out of the 3M Capital Hip experience, for achieving ‘inadequate’ cementation.


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 62 - 62
1 Jan 2003
Allami MK Chambers IR Sandher DS Gregg PJ
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Aims: To determine which radiological features were most significant in aseptic loosening (AL) of Charnley total hip replacement (THR) and to compare the prevalence of these features between a specialist hip surgeon and those from the general setting. Method: An analysis was performed of the initial post-operative radiographs of three groups of Charnley femoral stems: I: Failed stems within 5 years due to AL, as registered in the Trent Regional Arthroplasty Study (TRAS). II: 44 consecutive Charnley THRs performed by a single, ‘specialist’ hip surgeon. III Controls: A randomly selected cohort group from the TRAS (proven to be clinically and radiologically intact at 5 years). Results: The most significant radiographic features of failure were: (i) mantle width < 2mm in any zone giving an odds ratio of 21.0 for failure (CI 3.3 to∞; p< 0.05); (ii) “inadequate” cementation grade (Barrack grades C and D) giving an odds ratio of 9.5 for failure (CI 3.2 to 28; p< 0.05). The specialist hip surgeon achieved a significantly higher proportion (79.5%) of complete cement mantles (> 2mm) than the controls (50%) (Chi^2 = 9.455, df = 1, p=0.002). There were also a higher proportion of adequate cementation grades (88.6% vs 82%) although this difference was not significant (Chi^2= 0.947, df = 1, p=0.330). Conclusion: We have demonstrated features identified on radiographs of Charnley femoral stems predictive of failure. In our study a specialist hip surgeon achieved fewer flaws than those detected across a regional ‘average’. This suggests surgical technique can influence radiological results and thus outcome. This needs to be emphasized, particularly during training, in the hope of improving overall results in the future. However, even a specialist’s cementation appeared inadequate in 11.4% of cases, suggesting that factors outside the surgeon’s control, influence cement grading. This is important from a medico-legal standpoint because surgeons are being criticised for not achieving adequate cementation in negligence cases.