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Bone & Joint Open
Vol. 2, Issue 4 | Pages 261 - 270
1 Apr 2021
Hotchen AJ Khan SA Khan MA Seah M Charface ZH Khan Z Khan W Kang N Melton JTK McCaskie AW McDonnell SM

Aims

To investigate factors that contribute to patient decisions regarding attendance for arthroplasty during the COVID-19 pandemic.

Methods

A postal questionnaire was distributed to patients on the waiting list for hip or knee arthroplasty in a single tertiary centre within the UK. Patient factors that may have influenced the decision to attend for arthroplasty, global quality of life (QoL) (EuroQol five-dimension three-level (EQ-5D-3L)), and joint-specific QoL (Oxford Hip or Knee Score) were assessed. Patients were asked at which ‘COVID-alert’ level they would be willing to attend an NHS and a “COVID-light” hospital for arthroplasty. Independent predictors were assessed using multivariate logistic regression.


Bone & Joint Open
Vol. 1, Issue 12 | Pages 751 - 756
1 Dec 2020
Khan SA Logan P Asokan A Handford C Rajgor HD Khadabadi NA Moores T Targett J

Aims

As the first wave of the COVID-19 pandemic began to dip, restarting elective orthopaedics became a challenge. Protocols including surgery at ‘green’ sites, self-isolation for 14 days, and COVID-19 testing were developed to minimize the risk of transmission. In this study, we look at risk effects of 14-day self-isolation on the incidence of venous thromboembolism (VTE) in our green site hospital among patients undergoing total joint replacement (TJR).

Methods

This retrospective cohort study included 50 patients who underwent TJR. Basic demographic data was collected including, age, sex, American Society of Anesthesiologists (ASA) grade, body mass index (BMI), type of surgery, and complications at two and four weeks. Univariate and multivariate analysis were used to identify risk factors associated with an increased risk of VTE.


Bone & Joint Open
Vol. 1, Issue 11 | Pages 683 - 690
1 Nov 2020
Khan SA Asokan A Handford C Logan P Moores T

Background

Due to the overwhelming demand for trauma services, resulting from increasing emergency department attendances over the past decade, virtual fracture clinics (VFCs) have become the fashion to keep up with the demand and help comply with the BOA Standards for Trauma and Orthopaedics (BOAST) guidelines. In this article, we perform a systematic review asking, “How useful are VFCs?”, and what injuries and conditions can be treated safely and effectively, to help decrease patient face to face consultations. Our primary outcomes were patient satisfaction, clinical efficiency and cost analysis, and clinical outcomes.

Methods

We performed a systematic literature search of all papers pertaining to VFCs, using the search engines PubMed, MEDLINE, and the Cochrane Database, according to the Preferred Reporting Items for Systematic review and Meta-Analysis (PRISMA) checklist. Searches were carried out and screened by two authors, with final study eligibility confirmed by the senior author.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 445 - 445
1 Jul 2010
Kumar A Jha RK Khan SA Yadav CS Rastogi S Bakshi S
Full Access

Clear-cell sarcoma is a very rare tumor, and is almost always associated with tendons or aponeuroses or is metastatic from other organs. Sporadic cases only have been reported involving primarily the bone or extending from soft tissues to surrounding bones. To our knowledge, the ilium has not been previously reported as the primary site for clear cell sarcoma.

We report a rare case of Primary clear cell sarcoma involving right ilium region in a 18-year-old boy presented with a painful swelling over right ilium and limp on right lower limb of ten month duration. He was initially suspected having tuberculosis based on clinicoradiological evaluation and diagnosis of primry clear cell sarcoma could be established on histopathology. Patient was treated with partial excision of the ilium, the remaining ilium was fused with sacrum. Stabilization was achieved with a cortical autograft harvested from the right fibula and fixation with a titanium plate.

The patient had no local recurrences but the plate holding ilium to sacrum broke and was removed in the subsequent surgery after which he developed Trendelenberg’s gait.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 447 - 447
1 Jul 2010
Kumar V Manish K Javed A Khan SA Yadav CS Rastogi S
Full Access

Ossyfying periarticular lipoma is a very rare entity. Lipomas undergo involutional changes like chondrification, calcification and very rarely ossification. These changes result in altered clinical, radiological and histopathological features leading to diagnostic challenge in differentiation from the soft tissue tumor like synovial sarcoma, liposarcoma and rhabdomyosarcoma.

We present a series of three cases of ossifying lipomas presenting as soft tissue tumor around the knee, shoulder and hip joints. All the tumors revealed calcification and ossification on plain X-rays and on MRI/CT Scans. Clinico-radiological evaluation lead to a similar diagnostic dilemma in our series and a confirmed diagnosis of ossifying lipoma became possible only after histopathology. All the three tumors were excised completely without any recurrence during last 3 1/2 years of follow-up.

We recommend the early imaging by MRI/CT scan with closed core biopsy to exclude the malignant pathology and complete excision of the tumor with early mobilization of the adjacent joint.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 8 | Pages 1054 - 1057
1 Aug 2009
Kotwal PP Khan SA

A prospective series of 32 cases with tuberculosis of the hand and wrist is presented. The mean age of the patients was 23.9 years (3 to 65), 12 had bony disease and 20 primarily soft-tissue involvement. The metacarpal of the little finger was the most commonly involved bone. Pain and swelling were the usual presenting features and discharging sinuses were seen in three cases.

All patients were given anti-tubercular chemotherapy with four drugs. Operative treatment in the form of open or arthroscopic debridement, or incision and drainage of abscesses, was performed in those cases where no response was seen after eight weeks of ATT. Hand function was evaluated by the modified score of Green and O’Brien. The mean was 58.3 (25 to 80) before treatment and 90.5 (80 to 95) at the end. The mean follow-up was for 22.4 months (6 to 43). Conservative treatment was successful in 24 patients (75%). Eight who did not respond to chemotherapy within eight weeks required surgery.

Although tuberculosis of hand has a varied presentation, the majority of lesions respond to conservative treatment.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 543 - 543
1 Aug 2008
Khan SA Kharwadkar N Rawes ML
Full Access

Introduction: The objective of our study was to analyse the incidence of subsidence of an uncemented, hydroxyapatite coated, collarless prosthesis (Orthodynamics) and its impact on postoperative mobility in patients with fractured neck of femur.

Methods: 22 sets of case notes and X Rays were available for patients treated with the Orthodynamics hemiarthroplasty between February and November 2005. The mean age was 78 years (range 61 – 91 years). Analysis of standardised anteroposterior radiographs in the immediate postoperative period and at a mean interval of 14 weeks (ranging from 6 weeks to 64 weeks) was undertaken. Subsidence was calculated by measuring the reduction in the distance between the tip of lesser trochanter and a fixed point on the prosthesis.

Results: 18 of the 22 (81.8 %) cases showed subsidence of the prosthesis. The mean subsidence calculated was 9.1 millimetres (range 1 to 25 millimetres) and it showed no relationship to the postoperative interval at which it was calculated. Impact of subsidence on mobility state was assessed. Post operative mobility status was available for sixteen patients. Nine patients showed no change in the mobility at follow up. This group had a mean subsidence of 4.3 mm. Seven patients had a worsening of their mobility state. The mean subsidence in this group was 10.1 mm.

Discussion: Our study shows significant subsidence of an uncemented, collarless, hydroxyapatite coated prosthesis used for hip hemiarthroplasty and an associated worsening of mobility. We suggest that further review of this prosthesis is done and other proven prostheses used for hip hemiarthroplasty after a fractured neck of femur.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 6 | Pages 817 - 820
1 Jun 2007
Khan SA Varshney MK Hasan AS Kumar A Trikha V

A series of 14 patients suffering from tuberculosis of the sternum with a mean follow-up of 2.8 years (2 to 3.6) is presented. All were treated with antitubercular therapy: ten with primary therapy, two needed second-line therapy, and two required surgery (debridement). All showed complete healing and no evidence of recurrence at the last follow-up. MRI was useful in making the diagnosis at an early stage because atypical presentations resulting from HIV have become more common. Early adequate treatment with multidrug antitubercular therapy avoided the need for surgery in 12 of our 14 patients.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 10 | Pages 1388 - 1389
1 Oct 2006
Kumar A Varshney MK Trikha V Khan SA

Vertebral disease constitutes approximately 50% of all skeletal tuberculosis. We describe a patient who developed a discharging sinus at the tip of the coccyx. Extensive examination revealed isolated tuberculosis of the coccyx. Although rare, the condition should be suspected in patients presenting with a chronic sinus in the sacrococcygeal area and a lytic lesion in the coccyx on CT or MRI, particularly in the developing world.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 9 | Pages 1212 - 1216
1 Sep 2006
Rastogi S Varshney MK Trikha V Khan SA Choudhury B Safaya R

Aneurysmal bone cyst is a rare tumour-like lesion which develops during growth. Our aim was to determine the efficacy of the administration of percutaneous intralesional 3% polidocanol (hydroxypolyaethoxydodecan) as sclerotherapy.

Between July 1997 and December 2004 we treated 72 patients (46 males, 26 females) with a histologically-proven diagnosis of aneurysmal bone cyst, at various skeletal sites using this method. The sclerotherapy was performed under fluoroscopic guidance and general anaesthesia or sedation and local anaesthesia. The mean follow-up period was 34 months (26.5 to 80). The patients were evaluated using the Enneking system for functional assessment and all the lesions were radiologically quantified into four grades.

The mean age of patients was 15.6 years (3 to 38) and the mean number of injections was three (1 to 5). Ten patients were cured by a single injection. The mean reduction in size of the lesion (radiological healing) was found to be 76.6% (61.9% to 93.2%) with a mean clinical response of 84.5% (73.4% to 100%). Recurrence was seen in two patients (2.8%) within two years of treatment and both were treated successfully by further sclerotherapy.

Percutaneous sclerotherapy with polidocanol is a safe alternative to conventional surgery for the treatment of an aneurysmal bone cyst. It can be used at surgically-inaccessible sites and treatment can be performed on an out-patient basis.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 162 - 163
1 Apr 2005
Jacobs LGH Smith MG Khan SA
Full Access

Aims: To prospectively compare the progress and outcomes during a follow-up period of two years in patients who were in the ‘freezing phase’ of Primary (Idiopathic) Frozen Shoulder following either manipulation of the shoulder under general anaesthetic (MUA) or intra-articular shoulder joint distension injections using steroid and local anaesthetic.

Methods: 53 consecutive patients aged between 40 and 75 years with Frozen Shoulder were randomised to receive either MUA followed by out-patient physiotherapy or up to 3 distension injections at six weekly intervals in the first 12 weeks. Outcomes were measured using Constant-Murley Shoulder Function Assessment Score (CS), Visual Analogue Score (VAS) for pain level, and the SF-36 Health Evaluation Questionnaire. All patients were reviewed at 2, 6 and12 weeks, then at 6, 9, 12, 18 and 24 months. At each visit the CS and the VAS were repeated. The SF-36 was undertaken at initial and final visits.

Results: Group 1 (MUA) contained 28 patients of which 15 (54%) were female. Group 2 (Distension Injection) contained 25 patients of which 20 (80%) were female. No statistical difference was identified between the 2 groups in terms of outcome for the affected shoulders, for the SF36 scores, CS and the VAS. Maximum benefit was seen by 12 weeks in both groups. In group 2 this equated to 2 distension injections. No complications were noted in either group.

Conclusion: Frozen Shoulder is accepted to be a self-limiting condition with resolution by 2 years from onset. Any treatment aims to reduce this period of pain and disability. The potential risks of MUA include fracture and rotator cuff ruptures are well documented in the literature. Distension injections are easily performed in clinic without the need for admission, a general anaesthetic, or the risk of the complications associated with MUA. In view of there being no difference between the treatment modalities we recommend the use of 2 distension injections as the first line treatment for Frozen Shoulder.


The Journal of Bone & Joint Surgery British Volume
Vol. 86-B, Issue 4 | Pages 556 - 560
1 May 2004
Malik MHA Harwood P Diggle P Khan SA

We report a retrospective study over five years to determine the incidence of infection and nonunion after intramedullary nailing in fractures of 214 long bones; 122 femoral, 75 tibial and 17 humeral. The indications for nailing were trauma (n = 161), pathological fracture (n = 30) and nonunion (n = 23). There were 30 open fractures. The overall rates of deep infection and nonunion were 3.8% and 14.2%, respectively.

Using multiple logistic regression analysis, we determined the relationships between deep infection and nonunion and the pre- and peri-operative factors of age, ASA score, indication for nailing, the use of reaming, the use of antibiotics, whether the fracture was open and the operating time. Open fractures were found to be significantly associated with deep infection. The length of the operation may also affect the outcome. Opening of the fracture at the time of surgery and the ASA score were found to be significantly associated with the development of nonunion after intramedullary nailing.

We have compared our findings with previously published data from large teaching hospital units.