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General Orthopaedics

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Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_23 | Pages 55 - 55
1 Dec 2016
Walenkamp G Moojen DJ Hendriks H Goedendorp T Rademacher W Rozema F
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Aim

A previous Dutch guideline for prophylaxis of hematogenous PJI (HPJI) caused defensive medicine and incorrect own guidelines. There was a need for a better national guideline, developed cooperatively by orthopedic surgeons and dentist.

Method

A committee of Dutch Orthopedic and Dental Society, performed a systematic literature review to answer the question: “Is there a difference in the risk for hematogenous infection between always or never giving antibiotic prophylaxis to patients with a joint prosthesis undergoing a dental procedure”.

We included 9 papers as follows:

RCT's and systematic reviews: 539 abstracts > 33 full papers > 1 paper included.

observational studies: 289 abstracts > 12 full papers > 5 papers.

reference-to-reference: 3 papers.

The nine papers’ quality was scored according the GRADE method.

In addition we studied in non-included literature on further information about additional questions of pathophysiology, risk factors and risk procedures.