To determine the risk of total knee replacement (TKR) for primary osteoarthritis (OA) associated with overweight/obesity in the Australian population.

This population-based study analyzed 191,723 cases of TKR collected by the Australian Orthopaedic Association National Joint Registry and population data from the Australian Bureau of Statistics. The time-trend change in incidence of TKR relating to BMI was assessed between 2015-2018. The influence of obesity on the incidence of TKR in different age and gender groups was determined. The population attributable fraction (PAF) was then calculated to estimate the effect of obesity reduction on TKR incidence.

The greatest increase in incidence of TKR was seen in patients from obese class III. The incidence rate ratio for having a TKR for obesity class III was 28.683 at those aged 18-54 years but was 2.029 at those aged >75 years. Females in obesity class III were 1.7 times more likely to undergo TKR compared to similarly classified males. The PAFs of TKR associated with overweight or obesity was 35%, estimating 12,156 cases of TKR attributable to obesity in 2018. The proportion of TKRs could be reduced by 20% if overweight and obese population move down one category.

Obesity has resulted in a significant increase in the incidence of TKR in the youngest population in Australia. The impact of obesity is greatest in the young and the female population. Effective strategies to reduce the national obese population could potentially reduce 35% of the TKR, with over 10,000 cases being avoided.

While clinically important improvements in Oxford Shoulder Scores have been defined for patients with general shoulder problems or those undergoing subacromial decompression, no threshold has been reported for classifying improvement after shoulder replacement surgery. This study aimed to establish the minimal clinically important change (MCIC) for the Oxford Shoulder Score in patients undergoing primary total shoulder replacement (TSR).

Patient-reported outcomes data were sourced from the Australian Orthopaedic Association National Joint Replacement Registry Patient-Reported Outcome Measures Program. These included pre- and 6-month post-operative Oxford Shoulder Scores and a rating of patient-perceived change after surgery (5-point scale ranging from ‘much worse’ to ‘much better’). Two anchor-based methods (using patient-perceived improvement as the anchor) were used to calculate the MCIC: 1) mean change method; and 2) predictive modelling, with and without adjustment for the proportion of improved patients.

The analysis included 612 patients undergoing primary TSR who provided pre- and post-operative data (58% female; mean (SD) age 70 (8) years). Most patients (93%) reported improvement after surgery. The MCIC derived from the mean change method was 6.8 points (95%CI 4.7 to 8.9). Predictive modelling produced an MCIC estimate of 11.6 points (95%CI 8.9 to 15.6), which reduced to 8.7 points (95%CI 6.0 to 12.7) after adjustment for the proportion of improved patients.

For patient-reported outcome measures to provide valuable information that can support clinical care, we need to understand the magnitude of change that matters to patients. Using contemporary psychometric methods, this analysis has generated MCIC estimates for the Oxford Shoulder Score. These estimates can be used by clinicians and researchers to interpret important changes in pain and function after TSR from the patient's perspective. We conclude that an increase in Oxford Shoulder Scores of at least 9 points can be considered a meaningful improvement in shoulder-related pain and function after TSR.

The aim of this study was to examine the incidence of obesity in patients undergoing primary total shoulder replacement (TSR) (stemmed and reverse) for osteoarthritis (OA) in Australia compared to the incidence of obesity in the general population.

A 2017–18 cohort of 2,621 patients from the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) who underwent TSR, were compared with matched controls from the Australian Bureau of Statistics (ABS) National Health Survey from the same period. The two groups were analysed according to BMI category, sex and age.

According to the 2017–18 National Health Survey, 35.6% of Australian adults are overweight and 31.3% are obese. Of the primary TSR cases performed, 34.2% were overweight and 28.6% were obese. The relative risk of requiring TSR for OA increased with increasing BMI category. Class-3 obese females, aged 55–64, were 8.9 times more likely to require TSR compared to normal weight counterparts. Males in the same age and BMI category were 2.5 times more likely. Class-3 obese patients underwent TSR 4 years (female) and 7 years (male) sooner than their normal weight counterparts.

Our findings suggest that the obese population is at risk for early and more frequent TSR for OA. Previous studies demonstrate that obese patients undergoing TSR also exhibit increased risks of longer operative times, higher superficial infection rates, higher periprosthetic fracture rates, significantly reduced post-operative forward flexion range and greater revision rates.

Obesity significantly increases the risk of requiring TSR. To our knowledge this is the first study to publish data pertaining to age and BMI stratification of TSR Societal efforts are vital to diminish the prevalence and burden of obesity related TSR.

There may well be reversible pathophysiology in the obese population to address prior to surgery (adipokines, leptin, NMDA receptor upregulation). Surgery occurs due to recalcitrant or increased pain despite non-op Mx.

While clinically important improvements in Oxford Shoulder Scores have been defined for patients with general shoulder problems or those undergoing subacromial decompression, no threshold has been reported for classifying improvement after shoulder replacement surgery. This study aimed to establish the minimal clinically important change (MCIC) for the Oxford Shoulder Score in patients undergoing primary total shoulder replacement (TSR).

Patient-reported outcomes data were sourced from the Australian Orthopaedic Association National Joint Replacement Registry Patient-Reported Outcome Measures Program. These included pre- and 6-month post-operative Oxford Shoulder Scores and a rating of patient-perceived change after surgery (5-point scale ranging from ‘much worse’ to ‘much better’). Two anchor-based methods (using patient-perceived improvement as the anchor) were used to calculate the MCIC: 1) mean change method; and 2) predictive modelling, with and without adjustment for the proportion of improved patients.

The analysis included 612 patients undergoing primary TSR who provided pre- and post-operative data (58% female; mean (SD) age 70 (8) years). Most patients (93%) reported improvement after surgery. The MCIC derived from the mean change method was 6.8 points (95%CI 4.7 to 8.9). Predictive modelling produced an MCIC estimate of 11.6 points (95%CI 8.9 to 15.6), which reduced to 8.7 points (95%CI 6.0 to 12.7) after adjustment for the proportion of improved patients.

For patient-reported outcome measures to provide valuable information that can support clinical care, we need to understand the magnitude of change that matters to patients. Using contemporary psychometric methods, this analysis has generated MCIC estimates for the Oxford Shoulder Score. These estimates can be used by clinicians and researchers to interpret important changes in pain and function after TSR from the patient's perspective. We conclude that an increase in Oxford Shoulder Scores of at least 9 points can be considered a meaningful improvement in shoulder-related pain and function after TSR.

Obesity is a known risk factor for hip osteoarthritis. The aim of this study was to compare the incidence of obesity in Australians undergoing hip replacements (HR) for osteoarthritis to the general population.

A cohort study was conducted comparing data from the Australian Bureau of Statistics and the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) from 2017-18. Body mass index (BMI) data for patients undergoing primary total hip replacement and resurfacing for osteoarthritis were obtained from the AOANJRR. The distribution of HR patients by BMI category was compared to the general population, in age and sex sub-groups.

During the study period, 32,495 primary HR were performed for osteoarthritis in Australia. Compared to the general population, there was a higher incidence of Class I, II, and III obesity in patients undergoing HR in both sexes aged 35 to 74 years old. Class III obese females and males undergoing HR were on average 6 to 7 years younger than their normal weight counterparts. Class III obese females and males aged 55-64 years old were 2.9 and 1.7 times more likely to undergo HR, respectively (p<0.001).

There is a strong association between increased BMI and relative risk of undergoing HR. Similar findings have been noted in the United States of America, Canada, United Kingdom, Sweden and Spain. A New Zealand Registry study and recent meta-analysis have also found a concerning trend of Class III obese patients undergoing HR at a younger age.

Obese Australians are at increased risk of undergoing HR at a younger age. A national approach to address the prevalence of obesity is needed.

Increasing femoral offset in total hip replacement (THR) has several benefits including improved hip abductor strength and enhanced range of motion. Biomechanical studies have suggested that this may negatively impact on stem stability. However, it is unclear whether this has a clinical impact. Using data from the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR), the aim of this study was to determine the impact of stem offset and stem size for the three most common cementless THR prostheses revised for aseptic loosening.

The study period was September 1999 to December 2020. The study population included all primary procedures for osteoarthritis with a cementless THR using the Corail, Quadra-H and Polarstem. Procedures were divided into small and large stem sizes and by standard and high stem offset for each stem system. Hazard ratios (HR) from Cox proportional hazards models, adjusting for age and gender, were performed to compare revision for aseptic loosening for offset and stem size for each of the three femoral stems.

There were 55,194 Corail stems, 13,642 Quadra-H stem, and 13,736 Polarstem prostheses included in this study. For the Corail stem, offset had an impact only when small stems were used (sizes 8-11). Revision for aseptic loosening was increased for the high offset stem (HR=1.90;95% CI 1.53–2.37;p<0.001).

There was also a higher revision risk for aseptic loosening for high offset small size Quadra-H stems (sizes 0-3). Similar to the Corail stem, offset did not impact on the revision risk for larger stems (Corail sizes 12-20, Quadra-H sizes 4-7). The Polarstem did not show any difference in aseptic loosening revision risk when high and standard offset stems were compared, and this was irrespective of stem size.

High offset may be associated with increased revision for aseptic loosening, but this is both stem size and prosthesis specific.

Abstract

Deep infection after THA is a devastating complication that implies major suffering for the patients and large costs for society. Reports from multiple national and regional registries show increasing incidence of deep infection. Is this a consequence of improved diagnostics, changed virulence of the causative organism, increased co-morbidity of the patients?

An open database will be setup and hosted by an existing, high quality registry. All possible variables including patient demographic, detailed surgical information, bacteria/fungus characteristics, antibiotic treatment, radiographic findings and follow-up for 3 years will be collected. The incoming data will be displayed on a dashboard with continuous analyses and statistics. Any individual surgeon or hospital can report data.

A board with members from the International Hip Society and the International Society of Arthroplasty Registries will supervise the process and facilitate scientific analyses from collected data.

Total Hip Arthroplasty (THA) is a successful operation for the management of end stage hip osteoarthritis (OA) but long term success is limited by wear of the polyethylene bearing surface. The aim of this study was to compare the rate of revision at 15 years in patients <55 who had a THA for OA, and received either cross-linked (XLPE) or conventional non cross-linked polyethylene (non-XLPE).

The study population was all patients with primary THAs undertaken for OA from 1999 to 31 December 2016. Outcomes were determined for all procedures, comparing THA performed with non-XLPE and XLPE and including the effect of age, sex, and reason for revision. The principal outcome measure was time to first revision using Kaplan-Meier estimates of survivorship.

There were 17,869 procedures recorded for younger patients <55 years of age undergoing THA for OA and using either non XLPE or XLPE. There was a fivefold increase in the rate of revision for procedures using non-XLPE after seven years. The 15 year cumulative percent revision of primary THA performed for OA in patients <55 with non XLPE was 17.4% (95% CI 15.5,19.5) and for XLPE was 6.6% (95%CI 5.5,7.8) HR >7 years =5.3, p<0.001. Non-XLPE and XLPE were combined with three different femoral head bearing surfaces: ceramic, metal and ceramicised metal. Within each bearing surface, XLPE had a lower rate of revision than non-XLPE. For the most common head size of 28mm XLPE had a lower rate of revision.

The use of XLPE has resulted in a significant reduction in the rate of revision for younger patients undergoing THA for OA at 15 years. This evidence suggests that longevity of THA is likely to be improved and may enable younger patients to undergo surgery, confident of a reduced need for revision in the long term.

Background

The management of the patella during primary total knee arthroplasty (TKA) is controversial. Despite the majority of patients reporting excellent outcomes following TKA, a common complaint is anterior knee pain. Resurfacing of the patella at the time of initial surgery has been proposed as a means of preventing anterior knee pain, however current evidence, including four recent meta-analyses, has failed to show clear superiority of patellar resurfacing. Therefore, the purpose of this study was to estimate the cost-effectiveness of patellar resurfacing compared to non-resurfacing in TKA.

Introduction

Infection remains a serious complication following primary total hip arthroplasty (THA). Many factors including primary diagnosis, comorbidities and duration of procedure are known to influence the rate of infection. Although the association between patient and surgical factors is increasingly well understood, little is known about the role of the prosthesis. This analysis from the Australian Registry (AOANJRR) was undertaken to determine if revision for infection varied depending on the type of bearing surface used.

Aims

To report the rate of early revision (within two years) after shoulder arthroplasty and identify any patient, disease or prosthesis factors that may be associated with these early failures.

Femoral stems with exchangeable necks are a recent development in hip arthroplasty. They are proposed to be better in restoring offset and leg length while not compromising the fixation in the femoral canal. Few studies have been published on the clinical and functional outcome of modular neck hip system.

The Australian Joint registry data was analysed to evaluate the outcome after modular neck hip arthroplasties with the diagnosis of primary osteoarthritis. Only prostheses with data for more than 50 patients were studied. The indications for revision were identified. A comparison of outcomes with conventional hip arthroplasties was done.

The analysis confirmed that femoral stems with exchangeable necks have a significantly higher risk of revision compared to all other primary total conventional hip replacement (adj HR=2.13; 95% CI (1.88, 2.42), p<0.001). With the exception of three, all femoral stems with exchangeable necks have a higher rate of revision compared to primary total conventional hip replacement. The three exceptions have a short follow up. There is an increased incidence of revision for loosening and dislocation.

The recent registry data suggests that with end point being revision, the outcome of exchangeable neck hips are worse than conventional hips in patients with primary osteoarthritis of hip.

As there is currently no evidenced-based and systematic way of prioritising people requiring JRS we aimed to develop a clinically relevant system to improve prioritisation of people who may require JRS. An important challenge in this area is to accurately assign a queue position and improve list management. To identify priority criteria areas eight workshops were held with surgeons and patients. Domains derived were pain, activity limitations, psychosocial wellbeing, economic impact and deterioration. Draft questions were developed and refined through structured interviews with patients and consultation with consultants. 38 items survived critical appraisal and were mailed to 600 patients. Eleven items survived clinimetric and statistical item reduction.

Validation then included co-administration with standardised questionnaires (960 patients), verification of patient MAPT scores through clinical interview, examination of concordance with surgeon global ratings and test-retest.

Ninety-six Victorian surgeons weighted items using Discrete Choice Experiments (DCEs). The DCE scaling generated a scale, which clearly ranked patients across the disease continuum. The MAPT differentiated people on or not on waiting lists (p<0.001), and was highly correlated with other questionnaires, e.g., unweighted-MAPT vs WOMAC (r=0.78), Oxford Hip/Knee (r=0.86/0.75), Quality of Life (r=0.78), Depression (r=0.64), Anxiety (r=0.60), p<0.001 for all. Test-retest was excellent (ICC=0.89, n=90). Cronbachs reliability was also high 0.85. The MAPT is now routinely administered across all Victorian hospitals undertaking arthroplasty where the response rate is generally above 90%. In the hands of clinicians the MAPT has been used to facilitate fast-tracking of patients with the greatest need, monitoring for deterioration in those waiting for surgery or having a trial of non-operative treatment and deferment of surgery for those that may benefit from further non-operative treatments.

The MAPT is short, easy to complete and clinically relevant. It is a specific measure of severity of hip/knee arthritis and assigns priority for surgery. It has excellent psychometric and clinimetric properties evidenced by concordance with standard disease-specific and generic scales and widespread use and endorsement across health services.

Long waiting times and a growing demand on services for joint replacement surgery (JRS) prompted the Victorian Department of Human Services to fund a University of Melbourne/Melbourne Health partnership to develop and implement an osteoarthritis (OA) hip and knee service delivery and prioritisation system for those who may require JRS.

The service delivery model consists of a multidisciplinary team providing, comprehensive early assessment, evidence-based interventions, including support for patient self-management, continuity of care processes, and prioritisation for both surgical assessment and JRS. Prioritisation occurs via clinical assessment and the Hip and Knee Multi-Attribute Prioritisation Tool (MAPT), a patient, clinician, or proxy-administered 11-item questionnaire, resulting in a 100-point scale ranking of need for surgery. The Hip and Knee MAPT was developed using intensive consultation with surgeons, state-of-the-art clinimetrics and with input from patients, hospital management groups. Ninety-six surgeons contributed to the developing the final scoring system.

Over 4000 patients per year are entering the system across 14 hospitals in Victoria. Under the supervision of the orthopaedics unit, musculoskeletal coordinator (MSC), typically an experienced physiotherapist or nurse, as part of the multidisciplinary team, undertakes early comprehensive assessment, referral and prioritisation of patients with hip or knee OA referred to orthopaedic outpatient clinics. In addition, the MSC coordinates the monitoring and management of patients on the orthopaedic surgery waiting list. The processes enable patients who are most needy (via higher MAPT score and clinical assessment) to be fast-tracked to orthopaedic surgery; conversely those patients with lower scores receive prompt conservative management.

Time to first assessment and waiting times to see a surgeon for many patients have reduced from 12+ months to weeks. Patients seen by surgeons are more likely to be ready for surgery and have had more comprehensive non-operative optimisation. Patients placed on the surgical waiting list receive quarterly reassessments and evidence of deterioration is used as a basis for fast-tracking to surgery.

The OWL system is a whole of system(tm) approach informed by patients needs and surgeons needs. Clinicians have developed confidence in the clinical relevance of the MAPT scores. Uptake of the OWL model of care has been very high because it facilitates better care and better patient outcomes.

Hip fracture is a common cause of hospital admission and is often followed by reduced quality of life, or by death. International experiences indicate there are many benefits to be gained from national hip fracture registries. This pilot project aims to implement a hip fracture registry at three sites, a large metropolitan public hospital (Flinders Medical Centre), a large metropolitan private hospital (Epworth HealthCare) and a rural regional hospital (Goulburn Valley Health) to assess the feasibility of establishing a national registry.

Patients undergoing surgery for a hip fracture will be recruited from the three participating hospitals between March and September 2009. A minimum data set will be collected at discharge, from hospital records. Items include patient demographics, fracture descriptors, length of stay, residential status, mobility, health status, surgical details and discharge destination. A phone interview at four months after surgery will measure outcomes by using the Extended Glasgow Outcomes Scale and documenting residential status, mobility, hip pain and readmissions. Re- operations, if any, will be collected. The availability of data from State Health Departments for validation of hospital case data will be reported.

The pilot study is in progress at the time of writing. Ethical approval has been obtained, data collection, transmission and storage systems have been developed and deployed, and case data collection is underway. Case data will be summarised to describe hip fracture at the participating hospitals. Analysis will review the data elements in the pilot data set and assess their priority for inclusion in a national register—taking account of the quality of the data obtained and the time and other resources required for their collection. We will also evaluate the four-month review process. Any potential obstacles to a national registry that are identified during the pilot will be described and ways to overcome them will be proposed.

A national hip fracture registry will improve the quality of care and safety of patients following hip fracture by developing an efficient mechanism to compare and improve the effectiveness of acute health care delivery by all hospitals involved in the management of hip fractures.

The five year results of 8187 primary total knee replacements undertaken for osteoarthritis in patients under the age of 55 years are presented. The casese were submitted to the Australian Orthopaedic Association National Joint Replacement Registry in the period 1st September 1999 to 31st December 2006. This represents 6.3% of the 130,377 primary knee replacements recorded by the registry for this period.

The five year cumulative revision rate for patients under the age of 55 years was 8.0% (95% CI: 7.2 to 8.9). We compared the results to outcomes of older patients aged over 70 years at the time of surgery. The younger patients have a significantly higher risk of revision in the first five years (hazard ratio of 2.9; 95% CI= 2.59 to 3.26; p< 0.0001). Gender, mode of fixation, the use of cruciate retention or substitution prostheses or patella resurfacing did not significantly affect the rate of revision in those patients aged 55 years or less. Survival of fixed bearing implants was significantly better than that of mobile bearings. The most common reason for revision in this group was loosening (32.3%).

Total knee replacement in patients under the age of 55 years is associated with a much higher risk of revision in the first five years. A decision to proceed with total knee replacement in this age group should be accompanied by a careful explanation of this significantly increased risk compared to knee replacement in older individuals.

Introduction: In recent years some countries have shown increasing interest and use of unicompartmental knee arthroplasty (UKA). Several studies have reported increasing use of UKA for osteoarthritis in younger patients with low revision rates. The aim of this study was to determine the outcome of UKA by combining two national databases containing prospectively collected data.

Method: Over 50 000 UKA procedures were analyzed to determine the cumulative percentage revision (CPR). Any reason for revision was used as the end point. The analysis was stratified according to age, gender and type of prosthesis to determine outcomes in patients younger than 65 years

Result: In this study both countries showed declining use of UKA in terms of the proportion of knee replacement procedures and of absolute numbers undertaken per year. The seven year CPR of UKA in patients younger than 65 years was 16.2%, and at 10 years was 17.5%. No significant difference was found between gender, however outcome did vary depending on the type of prosthesis used.

Conclusion: This study reports the outcomes from the two largest databases of UKA. Within 10 years of UKA a substantial number of revisions were seen in patients younger than 65 years, with varying results depending on the type of prosthesis used.

Introduction: Although Hip Resurfacing Arthroplasty (HRA) has become a popular alternative to THR, the outcome of these procedures varies extensively between centres. This has been attributed to variations in patient selection, surgical experience, and patient volume. In this study we examine the effect of hospital volume on the outcome of hip resurfacing using a national database.

Methods: We examined data collected by the Australian Joint Registry between September 1999 and December 2006 relating to 8945 hip resurfacing procedures performed in 196 hospitals. Survivorship of the implanted components was calculated with revision as the end-point. The cumulative rate of revision at 4 years was compared between hospitals as a function of the number of cases performed during the study period (< 25, 25–49, 50–100, > 100 procedures). Using the log-rank test, differences in the risk of revision, corrected for age and sex of patients, were compared for low (< 25 cases) vs. higher volume centres (> 25 cases). We also estimated the number of cases/year of each centre and examined its apparent impact on revision rate.

Results: The majority (74%) of hospitals reporting performed less than 30 resurfacing procedures over the 7 year study period, with 64% of procedures performed at 16 “high volume” hospitals (> 100 cases), Overall, 249 of the 8945 resurfacing procedures (2.9%) were performed for revision of the original components. At 4 years, the cumulative revision rate dropped from 5.8% for hospitals performing less than 50 cases to 4.7% (50–99 cases) and 2.7% (> 100 cases) for larger volume centres. When adjusted for differences in patient age and sex, the risk of revision was 66% higher in hospitals performing < 25 cases. Based on the available data, the gap in revision rate between high and low volume centres is reduced by 50% once a surgeon’s operative volume exceeds 6 cases per year. On average, this corresponds to a learning curve of approximately 5 cases.

Conclusions: In this study, hospital volume is primarily a reflection of the operative experience of individual surgeons. Our results show that the outcome of hip resurfacing is strongly dependent on the experience of the surgeon and hospital performing the procedure. Even when adjusted for age and sex of the patients, the risk of revision increased by 66% when cases were performed at low volume centres. This supports the need for increased training of surgeons before undertaking hip resurfacing.

Introduction and aims: The extent of primary total hip and knee replacement revisions in the first 2 weeks following surgery is unknown. This study reports the incidence and reasons for revision of primary total hip and knee replacements within that period.

Method: Data was obtained from the Australian Orthopaedic Association National Joint Replacement Registry (AOA NJRR). The AOA NJRR began data collection in September 1999, becoming national during 2002. This is an analysis of patients whose conventional primary total hip and/or primary total knee replacement and subsequent revision are recorded by the AOA NJRR with a procedure date on or before the 31st December 2006. Patient demographics, method of fixation used in the primary procedure as well as reasons for revision, and type of revision (major or minor) were analysed.

Results: The analysis involved 104,234 conventional primary THR and 134,799 primary TKR. There were 286 revisions (0.27%) of primary THRs and 102 revisions (0.076%) of primary TKRs in the first 2 weeks following surgery. The risk of revision was significantly higher for THR than TKR (P< 0.0001).

Dislocation (44.1%) was the main reason for revision of primary THR in the first 2 weeks after surgery followed by fracture (26.8%) and loosening (16%). The main reason for revision of primary TKR was infection (39%) followed by loosening (18%) and fracture (8.6%).

Most revisions of primary THRs in the first 2 weeks were major (66.4%). When only one major component was revised it was mainly the femoral stem (32.9% of all revisions). Almost all of these were cementless (94.7%). When a revision of a primary TKR occurred the majority were minor (69.6%) (p< 0.001). The insert (64.7% of all revisions) was the main component revised.

Risk factors associated with primary THR revision include a diagnosis of developmental dysplasia (P=0.030) and cementless procedures had a significantly higher risk of revision than either cemented (P< 0.0001) or hybrid (P< 0.0001) procedures. We did not identify any risk factors associated with primary TKR in the first 2 weeks following surgery.

Conclusions: The number of revisions of primary THR and TKR within the first 2 weeks of surgery remains small with approximately 1.6 per 1,000 procedures revised. The risk of revision was significantly greater for THR than TKR. Surgical technique was the main reason for revision of primary THR and infection for primary TKR.

Current evidence suggests that in Australia more than 80% of individuals are not receiving treatment for osteoporosis following an initial osteoporotic fracture. The earliest opportunity to identify many individuals with osteoporosis is following their first osteoporotic fracture, which is usually less severe than subsequent fractures. As these fractures are usually treated by orthopaedic surgeons it was decided to survey Australian orthopaedic surgeons to determine their understanding, attitudes and involvement in the management of osteoporosis.

Methods: The AOA in conjunction with the BJD distributed a questionnaire to 945 members. The results of 449 (48%) returned questionnaires were collated and sent to the Swedish National Competence Centre for Musculo-skeletal Disorders for analysis.

Results: Responding surgeons claimed to treat at least 24,000 osteoporotic fractures per year. Sixty per cent felt they had ‘none’ or ‘insufficient’ training in osteoporosis and considered they had ‘no’ or only ‘slight knowledge’ in managing the condition. Approximately 65% of surgeons either ‘never’ or only ‘sometimes’ initiated investigation or treatment of patients with osteoporotic fractures; only 11% ‘always’ or ‘very often’ initiated investigation or treatment. If an osteoporotic fracture is suspected most (70%) refer to a GP or osteoporosis specialist, with only 22% evaluating the condition themselves. Although 46% claimed that they referred patients for a BMD study always or most of the time, only 14% did so routinely. Fifty percent felt it was the GP’s responsibility to identify and initiate the evaluation of the underlying osteoporosis of patients with fragility fractures, compared with 29% who considered that this was the orthopaedic surgeon’s responsibility.

Eighty five per cent of the respondents do not prescribe any pharmacological treatment for osteoporosis management. Most commonly (36%) there was a preference for surgery rather than drug prescription. Twenty four percent had access to a specific osteoporosis team for treating osteoporosis. No experience with treating osteoporosis (23%) and no formal education in osteoporosis (16%) were other common reasons. Very few orthopaedic surgeons felt it was their responsibility to treat osteoporosis, however 52% were interested in attending a course on osteoporosis.

The findings are contrasted with those of an international study conducted by the Bone and Joint Decade and the International Osteoporosis Foundation, using the same questionnaire.

Conclusions: The evidence of under- treatment of osteoporosis after first fragility fractures, suggests that it may be necessary for orthopaedic surgeons to re-evaluate their approach to the management of osteoporosis, either by themselves or others. Further educational opportunities in this area should be considered.

Traditionally autologous bone graft is the standard treatment for non-union of fractures. More recently osteo-inductive agents with or without allograft have been utilised. A trial of Autologous Mesenchymal Precursor Cells has been completed at the Royal Melbourne Hospital to investigate their potential for the treatment of nonunion of long bone fractures.

With the approval of the ethics committee at the Royal Melbourne Hospital a human safety trial was commenced for the treatment of fracture non-union. Bone marrow cells were harvested from patients approximately six weeks before surgery and cultured in a laboratory. The cells were expanded in a culture medium. At the time of definitive surgery the stem cells were implanted on a hydroxy apatite/tricalcium phosphate matrix to the non-union site. Any further fixation that was required at the time of the union was performed by the treating surgeon. Investigations were performed at regular intervals to assess for union and for any reaction to the stem cells and growth medium.

The trial has been completed and eleven patients have been entered into the study. There were eight patients with non-union of femoral fractures and four patients with tibial non-unions (one patient with ipsilateral injuries to both bones). The average age was 41.9 years and the mean time to surgery from the initial injury was 15.2 months. Eight patients have united at a mean time of 24 weeks. One is well on the way to union and of the remaining two patients one is listed as uncertain and one a declared non union. The patient who has failed to unite is currently awaiting further surgery. One patient withdrew from the trial after ceasing smoking and finally uniting prior to stem cell implantation. There has been one adverse event with possible infection at a screw site though this was thought not to be related to stem cell therapy.

This is a phase one safety trial of a new development for the treatment of a nonunion of long bone fractures. The results are promising with the regards to achieving bone union without any significant complications. This paves the way for a trial involving allogeneic stem cells.

Computer navigation was introduced in Australia in 2000, initially with the use of pre-operative computer scans and then later with image free systems. In 2003 the AOA – NJRR began collecting data for knee replacement performed with computer navigation.

Meta analysis of the literature has shown better coronal and sagittal plane alignment in total knee arthroplasty performed with computer navigation as opposed to standard instrumented knee replacement. At present, however, there is no data on improved outcomes or reduced revision rates. Information was requested from the AOA – NJRR on the use of computer navigation for both uni-compartmental and total knee replacements. This included numbers of navigated knees done per year as well as revision rates and reasons for revisions of knees performed by computer navigation surgery.

Since data collection began there has been 2,651 computer assisted total knee replacements performed which is 4.1% of the total number of knee replacements in this time period. There has been a steady increase in the last three years in the use of computer navigation. There has been an increased number of computer navigated knees performed in the private hospital sector as opposed to the public hospitals and there is a state by state variation in the uptake of navigation. The revision rate per 100 observed ‘component’ years at three years is 2.8 for non computer assisted and 2.5 computer assisted surgery. This is not statistically significant. There is no difference in the early complication rate leading to revision.

The use of computer navigation could be expected to reduce the long term revision rates of knee arthroplasty due to better alignment and potentially less wear. In the short term there is no significant revision rate between the two methods of performing TKR particularly with regard to infection or fracture

Introduction: Dislocation remains one of the most common orthopaedic complications of hip replacement. Surgical technique, implant design and patient factors have been suggested as risk factors. The 2005 AOA Joint Registry recorded data on 101, 952 hip procedures between 1999 and 2004. We analyzed risk factors for early revision in this group of patients.

Methods: Ethics approval was obtained then a formal application was made to the Australian Joint Registry to release the required data. All primary hip replacements between 1/09/1999 – 31/12/2004 were studied. Statistical analyses of traditional risk factors including initial diagnosis, sex, age and head size were performed. We also studied the effect of fixation method on revision for dislocation.

Results: A total of 65,992 primary hip replacements across all diagnoses groups recorded were investigated with regard to diagnosis. The only initial diagnoses with significantly increased relative risk (RR) of revision for dislocation compared to osteoarthritis was fractured neck of femur (RR 2.25, p< 0.0001) and rheumatoid arthritis (RR 1.9, p< 0.01).

58,109 primary hip replacements for osteoarthritis were investigated for effect of age group, sex and fixation method. Age group and sex were not significant risk factors in revision for dislocation. Studying fixation method, cementless acetabular components were implanted more frequently (49,027, 84%) than cemented (9,082, 15.6%). In total, there were 428 (0.7%) revisions for dislocation, 369(0.8%) with a cementless acetabulum and 59 (0.6%) with cemented. Relative risk (cementless v cemented acetabulum adjusted for age group, sex and head size) of 1.59 (CI 1.19 to 2.12, p< 0.01). Head sizes of > 30mm, 28mm, 26mm and 22mm had significantly increasing relative risk (p< 0.001).

Discussion: The results from this large database indicate rheumatoid patients and those after fractured neck of femur have increased risk of revision for dislocation compared to osteoarthritis. Many of the traditional groups thought to be at higher risk of dislocation were not associated with an increased risk of revision for dislocation. These included age group, sex, avascular necrosis, developmental dysplasia and failed internal fixation. Cementless acetabuli have a higher rate of revision for dislocation. This has not been previously reported. Further investigation is needed to identify the cause of this finding.

There is an increased early postoperative mortality (operation risk) after joint replacement surgery. This mortality is normally associated with cardiovascular events, such as deep venous thrombosis, pulmonary embolism, and ischemic heart diseases.

Our objective was to quantify the magnitude of the increased mortality and how long the mortality after an operation persists.

We focused on the early postoperative mortality after surgery for total knee and total hip replacements from the national registries in Australia and Norway, which cover more than 95% of all operations in the two nations. Only osteoarthritis patients between 50 and 80 years of age were included. A total of 244.275 patients remained for analyses.

Smoothed intensity curves were calculated for the early postoperative period. Effects of risk factors were studied using a non-parametric proportional hazards model.

The mortality was highest immediately after the operation (~1 deaths per 10.000 patients per day), and it decreased until the 3rd postoperative week. The mortality was virtually the same for both nations and both joints. Mortality increased with age and was higher for males than for females.

A possible reduction of early postoperative mortality is plausible for the immediate postoperative period, and no longer than the 3rd postoperative week.

Introduction and Aims: There is a paucity of comprehensive information regarding the management and outcomes of orthopaedic trauma. The aims of this project are to establish a comprehensive registry of orthopaedic injuries, treatments, complications and outcomes based on admissions to Level One Trauma Centres in Victoria.

Method: The Victorian Orthopaedic Trauma Outcomes Registry (VOTOR) has been established through a collaborative project involving Monash University and the Alfred and Royal Melbourne Hospitals. The registry prospectively collects data on all patients with an orthopaedic (bone or soft tissue) injury that are admitted to Victorian Level One Trauma Centres and are managed or followed-up by an orthopaedic unit or have a spinal injury. Data is collected from the patient’s medical record and includes information on demographics, injury diagnosis and treatment methods. Outcomes are measured at discharge and six and 12 months post-injury using patient-oriented measures.

Results: The VOTOR database was established in 2003. This process involved two key stages. The first stage was based on the development of standardised data collection methodology and quality control processes specific to orthopaedic trauma. The second stage involved the commencement of data collection and the administration of outcome measures. From August 18, 2003 until January 12, 2004, 850 participants were registered on the database and there was a greater than 80% response rate for administration of discharge outcome measures. The participants had a median age of 44 (range 16–104) years. There was a greater percentage of male patients (60%) than female patients (40%) and English was the preferred language for most participants (87%). Fortyfive percent of patients were provided with funding from the Transport Accident Commission (TAC). With respect to pre-injury status, the greatest proportion of participants were retired or pensioners (32%), while 14% were tradespersons and 11% had a professional occupation. Most participants achieved an education level of Year 9–11 (32%), followed by 19 percent that reached Year 12.

Conclusion: The VOTOR database provides a unique opportunity to comprehensively examine the nature of orthopaedic trauma. Patient-oriented outcomes associated with these injuries are currently being collected. This research is essential in determining the efficacy of different treatment methods, improving current management options and ultimately reducing the financial and social costs of orthopaedic trauma.

Introduction and Aims: Nine countries have established national joint replacement registries. The first population-based national registry, the Swedish Knee Registry, was established in 1975 with the most recent, the UK National Joint Registry (UK NJR), beginning in 2003. We identify commonalities and differences in the structure, function and methods of reporting among these national registries.

Method: Data was collected from the annual reports of the various registries, published literature and personal contact with registry coordinators and directors.

Results: Commonalities include registry ownership, source of funding, procedure types collected, method of data collection and validation of data. Most registries are owned by the national Orthopaedic Association or a government agency. The most common source of funding is government; membership fees and a mandated implant levy are also used. Most national registries collect total hip and knee replacements, primaries and revisions. Hemiarthroplasties are not commonly collected, though some registries collect additional joints (including shoulder, elbow, wrist, finger, ankle and toe). The most common method of data collection is paper-based, usually from theatre, with subsequent data entry at the registry. Electronic data collection is used to supplement the paper-based system in some countries, while the Swedish Hip Registry and the UK NJR utilise a web application for the submission of data. Most registries attempt to validate their data against hospital inpatient data held by government. Differences include reporting of rates, cost per registration and definitions. Failures of primary implants may be reported as cumulative proportions, true incidence rates or survival probabilities. This leads to difficulties in comparison of data among the national registries. The cost of registering a procedure varies up to five-fold across countries.

Conclusion: There are obvious opportunities for collaboration between national joint replacement registries, however some issues need to be addressed. These include definitions of what is collected, for example hemiarthroplasties, and methods of analysis and reporting, especially revision rates.

Introduction and Aim: Following the establishment of the Australian Orthopaedic Association National Joint Replacement Registry, the Australian orthopaedic community has quality prosthesis specific information on knee replacement. This presentation details the demographics of primary total knee replacement, types of prostheses used, methods of fixation and the incidence of, and reasons for, early revision.

Results: Over 36,000 primary total knee replacements with almost 400 subsequent revisions were recorded. Primary total knee replacements were undertaken more commonly in females (56.4%), mostly for osteoarthritis (95.9%), with a mean subject age of 69.6 years.

The Registry recorded 56 different knee prostheses with the 10 most common accounting for 85.5% of all procedures. The patella was not replaced in the majority of cases (58.5%), however this varied considerably with prosthesis type and method of fixation. Cement fixation of the tibial component occurred in 76.9% of cases and the femoral component in 49.5%. Most commonly the insert was fixed (71.3%) and minimally stabilised (86.7%). Posterior stabilised inserts were used in 12.8% of primary cases. The cumulative revision rate at one year was 1.0% and 2.1% at two years. Early revision was minor in 54.1% of cases and major in the remainder. The most common reasons for minor revision were patello-femoral pain (27.1%) and infection (21.7%); for major revision, early loosening (40.2%) and infection (27.5%). Prosthesis type, patella use, method of fixation, degree of constraint and the use of fixed, rotating and/or sliding inserts did not significantly affect revision rates at this early stage.

Conclusion: Although variation is seen in early revision rates depending on the prosthesis type, patella use, method of fixation and other prosthesis specific characteristics, these differences are currently not significant.

Introduction and Aims: The use of resurfacing hip replacements has increased dramatically in recent years. The aim of this study was to compare the early results of this treatment with conventional cemented, cementless and hybrid primary total hip replacement in Australia.

Method: The data used for this report included all conventional primary total hip and resurfacing procedures, as well as any subsequent revisions of those procedures which had been undertaken and reported to the Australian Orthopaedic Association National Joint Replacement Registry (AOA NJRR) before 31 December 2002. Analysis included the determination of demographics, components used and method of fixation. Early revision rates and reasons for failure were also assessed. The AOA NJRR commenced data collection in September 1999 and has had national coverage since 2002, therefore any results reported at this stage are early outcomes.

Results: Almost 33,000 primary total hip replacements were recorded, of these 2130 were resurfacing procedures (6.5%). This proportion of resurfacing was consistent across states with the exceptions of Victoria (11%) and Tasmania (0.6%). Cementless hip replacement was the most common form of primary total hip replacement (41%) with hybrid (34%) and cemented (18.2 %) less common. There was marked state variation in the proportion of cemented and cementless fixation with NSW having a low proportion of cement fixation (4.5%). Early revision rates for cemented conventional primary total hip replacement are significantly less compared to cementless and hybrid hips (cemented v cementless) hazard ratio (adjusted for age and sex) 2.13; 95% CI (1.49, 3.05) p< 0.0001) (cemented v hybrid) hazard ratio (adjusted for age and sex) 1.94; 95% CI (1.37, 2.77) p=0.0002). There was no difference between cementless and hybrid hips. The most common reason for early revision was dislocation and the risk of this was related to head size with larger sizes showing a reduced risk. Although revisions per 100 observed component years were higher for resurfacing hip replacements than for conventional hips (1.73 v 1.18), this difference was not statistically significant. The principal reason for early failure of resurfacing hips was fracture.

Conclusion: The AOA NJRR has identified prosthesis specific differences in early outcomes and failure mechanisms following primary total hip replacement. Continued monitoring of existing and new prostheses will provide surgeons with independent quality information to assist in the selection of the most appropriate prostheses for particular clinical situations.

Introduction and Aims: Austin Moore and Thompson hemiarthroplasties are commonly used for the management of subcapital neck of femur fractures, particularly in the frail elderly. There are no published studies that directly compare the results of these two procedures. The Australian Orthopaedic Association National Joint Replacement Registry (AOA NJRR) has reviewed outcomes for these prostheses.

Method: Data from the AOA NJRR collected from participating hospitals between September 1999 and December 2002 were used to test for differences in revision rates between these two prostheses. Mortality data from the National Death Index were used to censor the time of follow-up and to compare mortality rates following surgery. Further analyses were undertaken to examine the effects of age, gender, diagnosis and regional variation.

Results: The Registry recorded 4080 Austin Moore and 1111 Thompson hemiarthroplasties. Of these, 4023 (98.6%) Austin Moore prostheses were cementless and 1010 (90.9%) Thompsons were cemented. The distributions of age and gender were similar for the two prostheses. There were regional differences in the use of monoblock prostheses during the data collection period. In Victoria, all partial monoblock prostheses used were Austin Moore (N=1560). This contrasts to Queensland and Western Australia where 62.8% and 75.8% respectively of all partial monoblock hip replacements were Thompsons. The cementless Austin Moore prosthesis had a significantly higher rate of revision (122/4023, 3%) than the cemented Thompson prosthesis (9/1010, 0.9%). A Cox model yielded a hazard ratio, adjusted for age and gender, of 3.94 (95% CI: 2.00, 7.76; p < 0.001). None of the 57 cemented Austin Moore and four of the 101 (4%) cementless Thompsons required revision. The cumulative mortality rates for the period to 2001 were similar for the two prostheses (Austin Moore 23.3% and Thompson 24.0%). In the states where sufficient numbers of both types of prostheses were used the difference in outcomes were consistent with the overall results.

Conclusion: The use of the cementless Austin Moore prostheses is associated with an almost four-fold increase in the rate of revision when compared to the cemented Thompson prosthesis.

Introduction Early complications of revision total hip replacement (rTHR) with femoral impaction allografting have included stem subsidence and loosening. In this comparative study, the impact of new techniques, including the use of longer stems, non-irradiated washed allograft, larger bone chips and medial mesh, on early clinical and radiographic outcomes was examined.

Methods The initial series of rTHRs with femoral impaction allografting comprised 20 hips (19 patients, median age 68 years) with a median follow-up of eight years. In the current series where the new techniques were used, there are 11 hips (11 patients, median age 69 years) with a median follow-up of 1.5 years. Three surgeons at one hospital undertook all rTHRs using a polished cemented collarless double tapered stem. Patients were mobilised on day one with partial weight bearing for 12 weeks. The femoral deficiencies commonly comprised extensive cavitatory loss combined with segmental deficiencies. Regular clinical and radiographic assessment was undertaken.

Results In the initial series, there were three early rerevisions for subsidence and stem loosening and one rerevision for infection. Periprosthetic fracture occurred early in three hips. EBRA FCA was used to assess stem subsidence. By two to four years, nine femoral stems had subsided more than five millimetres. At mid-term follow-up of eight years there have been no further rerevisions. In comparison, there has been minimal stem subsidence in the current series, with no stems subsiding more than five millimetres. To-date there have been no periprosthetic fractures and no complications requiring re-revision.

Conclusions Prospective monitoring of rTHR is important to identify factors that may be associated with poor outcome. Current techniques of femoral impaction grafting at rTHR, that includes washing of allograft and the use of long length stems and proximal mesh support yield good early-term radiographic and clinical results.

With increasing primary joint replacement procedures and an ageing population surviving longer, the rate of revision surgery will increase. Revision surgery, however, is associated with increased morbidity and mortality and has a far less successful outcome than primary joint replacement. The mid- to long-term survival rate of the large variety of replacement prostheses remains unknown. Inadequate outcomes data for the majority of prostheses, as well as variability related to different surgical techniques and diagnostic groups, have made it difficult for surgeons to identify the relative effectiveness of different prostheses and treatments. The Federal Government provided funding to the Australian Orthopaedic Association (AOA) to establish the National Joint Replacement Registry (NJRR) in March 1998. The AOA has appointed a committee to manage the Registry and has contracted with the Data Management and Analysis Centre at the University of Adelaide to establish and manage the data systems for the Registry.

The primary aim of the AOA NJRR is to evaluate the effectiveness of different types of joint replacement prostheses and surgical techniques at a national level.

Implementation methods, aspects of database design and early progress in data collection are presented.

Introduction: There has been significant development in computer technology in recent years and this has led to applications in orthopaedic surgery. Of particular interest is computer assisted joint arthroplasty to enable accurate insertion of the components based on CT generated images of the patient’s bones.

Methods: Twenty-five patients have undergone computer assisted total knee arthroplasty using a computer guidance system (Vector Vision, Brain Lab, Munich) implanting a PFC cruciate retaining total knee replacement (TKR) (Depuy, Leeds). Pre-operative CT scans were obtained from each patient and alignment and sizing were calculated before surgery. Intra-operatively, an infrared camera tracked the instruments and the patient’s limb was accurately mapped in space by surface matching the bone and comparing it with the CT scan. For the purpose of the study the computer generated alignments and sizing were evaluated along with the use of traditional instruments and stored in a database.

Results: These have been evaluated comparing computer assisted and instrumented knee arthroplasty. Variables measured include the AP femoral cuts, rotational femoral alignment, and tibial axis alignment in AP and lateral planes.

Conclusions: Computer assisted orthopaedic surgery has undergone a rapid development in the last 18 months to enable real-time intra-operative images to be viewed in a moving limb with a degree of accuracy previously not possible. The use of this technology may lead to more accurate alignment of hip and knee prostheses and therefor help to reduce wear in the long-term.

Introduction: Patient education and informed consent are areas of clinical practice that are taking an ever-increasing proportion of a surgeon’s time and effort. The expectation is that this trend will continue, as medical malpractice litigation becomes more commonplace. Patients are also requiring increased access to medical information to help facilitate decisions about their healthcare. With the increasing use of computers and improvements in technology modules to aid patients’ understanding have become available and may prove useful in patient education.

Method: A computer-based multimedia module of total hip replacement (THR) has been developed. These involve three-dimensional (3D), animated computer graphics with text and spoken word. A questionnaire based on educational models was designed to test ease of use and patients’ comprehension after viewing the module.

Results: A pilot study involved 20 patients each awaiting elective surgery for THR. The results showed a good comprehension and understanding of the nature of the surgery and the possible complications.

Conclusions: We have shown that a 3D-multimedia patient education module improved patients’ understanding of THR surgery and its possible complications. The use of 3D multimedia modules has the potential to save the surgeon time whilst ensuring that his/her patients have given informed consent to their forthcoming surgery. It is hoped that better-informed consent may equate to a reduction in medical malpractice activity and thus insurance premiums.

Introduction: THR and TKR have been shown to be successful treatments for moderate to severe osteoarthritis of the hip and knee. The requirement for total joint replacement will increase as the population ages. This study reports on the incidence of THR and TKR in an Australian population.

Method: Age and gender specific numbers of THR and TKR for the Australian population, 1994–1998 were obtained from the Australian Institute of Health and Welfare. The same data for South Australia, 1988–1998 were obtained from the Department of Human Services Epidemiology Branch. The incidences were calculated and tested for changes over time.

Results: For the Australian population in 1994 there were 9,120 THR and by 1998 this had increased by 25.9% to 11,488 THR. There were 10,132 TKR in 1994 and by 1998 this had increased by 42.8% to 14,472 TKR. Stratified by age group changes in incidence rate with respect to time was statistically tested using regression analysis. For the eleven year data from South Australia there was a significant increase in the overall incidence of THR (p=0.012). There were significant increases in TKR incidence, although this increase was not uniform across all age groups (p< 0.001). The increase in TKR incidence was greater than that for THR. For both THR and TKR there were no significant differences on the basis of gender.

Conclusion: The incidence of THR is increasing in Australia and TKR incidence is increasing at a greater rate. Future projections must take into account these changing incidences as well as changes in population demographics.