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Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_6 | Pages 117 - 117
1 Jul 2020
Fletcher J Neumann V Wenzel L Richards G Gueorguiev B Gill H Whitehouse M Preatoni E
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Nearly a quarter of screws cause damage during insertion by stripping the bone, reducing pullout strength by over 80%. Studies assessing surgically achieved tightness have predominately shown that variations between individual surgeons can lead to underpowered investigations. Further to the variables that have been previously explored, several basic aspects related to tightening screws have not been evaluated with regards to how they affect screw insertion. This study aims to identify the achieved tightness for several variables, firstly to better understand factors related to achieving optimal intraoperative screw purchase and secondly to establish improved methodologies for future studies.

Two torque screwdrivers were used consecutively by two orthopaedic surgeons to insert 60 cortical, non-locking, stainless-steel screws of 3.5 mm diameter through a 3.5 mm plate, into custom-made 4 mm thick 20 PCF sheets of Sawbone, mounted on a custom-made jig. Screws were inserted to optimal tightness subjectively chosen by each surgeon. The jig was attached to a bench for vertical screw insertion, before a further 60 screws were inserted using the first torque screwdriver with the jig mounted vertically, enabling horizontal screw insertion. Following the decision to use the first screwdriver to insert the remaining screws in the vertical position for the other variables, the following test parameters were assessed with 60 screws inserted per surgeon: without gloves, double surgical gloves, single surgical gloves, non-sterile nitrile gloves and, with and then without augmented feedback (using digitally displayed real-time achieved torque). For all tests, except when augmented feedback was used, the surgeon was blinded to the insertion torque. Once the stopping torque was reached, screws were tightened until the stripping torque was found, this being used to calculate tightness (stopping/stripping torque ratio). Screws were recorded to have stripped the material if the stopping torque was greater than the stripping torque. Following tests of normality, Mann-Whitney-U comparisons were performed between and combining both surgeons for each variable, with Bonferroni corrections for multiple comparisons.

There was no significant (p=0.29) difference in the achieved tightness between different torque screw drivers nor different jig positions (p=0.53). The use of any gloves led to significant (p < 0 .001) increases in achieved tightness compared to not using gloves for one surgeon but made no difference for the other (p=0.38–0.74). Using augmented feedback was found to virtually eliminate stripping. For one surgeon average tightness increased significantly (p < 0 .001) when torque values were displayed from 55 to 75%, whilst for the other, this was associated with significantly decreases (p < 0 .001), 72 to 57%, both surgeons returned to their pre-augmentation tightness when it was removed.

Individual techniques make a considerable difference to the impact from some variables involved when inserting screws. However, the orientation of screws insertion and the type of screwdriver did not affect achieved screw tightness. Using visual feedback reduces rates of stripping and investigating ways to incorporate this into clinical use are recommended. Further work is underway into the effect of other variables such as bone density and cortical thickness.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_3 | Pages 49 - 49
1 Jan 2016
Monk A Mellon S Chen M Beard D Gill H Murray D
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Introduction

Knee arthroplasty is an effective intervention for painful arthritis when conservative measures have failed. Despite recent advances in component design and implantation techniques, a significant proportion of patients experience problems relating to the patella-femoral joint (PFJ).

Detailed knowledge of the shape and orientation of the normal and replaced femoral trochlea groove is critical when considering potential causes of anterior knee pain. Furthermore, to date it has proved difficult to establish a diagnosis due to shortcomings in current imaging techniques for obtaining satisfactory coronal plane motion data of the patella in the replaced knee.

The aim of this study was to correlate the trochlea shape of normal and replaced knees with corresponding coronal plane PFJ kinematic data.

Method

Bony and cartilagenous trochlea geometries from 3T MRI scans of 20 normal healthy volunteers were compared with both anatomical and standard total knee replacements (TKR) and patellofemoral joint replacement (PFJR) geometries. Following segmentation and standardized alignment, the path of the apex of the trochlea groove was measured using customized Matlab software. (Fig1).

Next, kinematic data of the 20 normal healthy volunteers (Normal) was compared with that of 20 TKR, and 20 PFJR patients using the validated MAUSTM system (Motion Analysis and UltraSound) comprising a 12-camera, motion capture system used to capture images of reflective markers mounted on subjects lower limbs and an ultrasound probe. A mapping between the ultrasound image and the motion capture system allows the ultrasound probe to be used to determine the locations of the patella relative to bony landmarks on the femur during a squat exercise.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_26 | Pages 10 - 10
1 Jun 2013
Monk A Chen M Mellon S Gibbons M Beard D Murray D Gill H
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Previous attempts to measure coronal plane patellofemoral kinematics following knee replacement have suffered from methodological drawbacks; the patella being obscured by the components, metal artefact and technical inaccuracies. The aim of this study was to assess whether there was any significant difference in the patellofemoral kinematics between normal, TKR and PFJR patients using the validated MAUS™ technique (combining motion analysis with ultrasound).

60 patients were recruited into three groups; normal healthy volunteers (Normal), TKR, and PFJR patients. The MAUS technique incorporates a 12 camera analysis system (providing gross alignment data for tibial and femoral segments) and an ultrasound probe (providing coordinates of bony landmarks on patella femur and tibia) during a squat exercise. 6 DOF kinematics were described between 0 and 90° flexion. The validated accuracy of the MAUS technique registering the ultrasound images within the motion capture system is 1.84 mm (2 × SD).

Movements of the Normal group were significantly different from the TKR group (p=0.03) and the PFJR group (p<0.01), whilst there was no significant difference between the TKR and PFJR groups (p=0.27).

Our data suggest that many aspects of patellofemoral kinematics are absent following TKR and PFJR, which could be addressed in future designs of knee TKR and PFJR.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 67 - 67
1 Jan 2013
Liddle A Pandit H Jenkins C Price A Gill H Dodd C Murray D
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Unicompartmental Knee Replacement (UKR) is associated with fewer complications, faster recovery and better function than Total Knee Replacement (TKR). However, joint registries demonstrate a higher revision rate in UKR, limiting its use. Currently most UKRs are cemented and performed using a minimally invasive technique. In joint registries, common reasons for revision include aseptic loosening and pain. These problems could potentially be addressed by using cementless implants, which may provide more reliable fixation.

The objectives of this study were to compare the quality of fixation (determined by the incidence and appearance of radiolucencies), and clinical outcomes of cemented and cementless UKR at five years.

A randomised controlled trial was established with 63 knees (62 patients) randomised to either cemented (32 patients) or cementless UKR (30 patients). Fixation was assessed with fluoroscopic radiographs aligned to the bone-implant interface at one and five years. Outcome scores were collected pre-operatively and at one, two and five years, including Oxford Knee Score (OKS), American Knee Society Score, objective and functional (AKSS-O/F) and Tegner Activity Scale (TAS), expressed as absolute scores and 0–5 year change (δ) scores.

Four patients died during the study period. There were no revisions. Mean operative time was 11 minutes shorter in the cementless group (p=0.029). At five years, there was no significant difference in any outcome measure except AKSS-F and δAKSS-F which were significantly better in the cementless group (both p=0.003). There were no femoral radiolucencies in either group. There were significantly more tibial radiolucencies in the cemented group (20/30 vs 2/27, p< 0.001). There were nine complete radiolucencies in the cemented group and none in the cementless group (p< 0.001).

Cementless fixation provides improved fixation at five years compared to cemented fixation in UKR, maintaining equivalent or superior clinical outcomes with a shorter operative time and no increase in complications.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 19 - 19
1 Jan 2013
Thomas G Batra R Kiran A Palmer A Gibbons C Gundle R Hart D Spector T Gill H Javaid M Carr A Arden N Glyn-Jones S
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Introduction

Subtle deformities of the acetabulum and proximal femur are recognised as biomechanical risk factors for the development of hip osteoarthritis (OA) as well as a cause of hip and groin pain. We undertook this study to examine relationships between a number of morphological measurements of the acetabulum and proximal femur and the hip pain in a 20-year longitudinal study.

Methods

In 1989 women of 45–64 years of age were recruited. Each had an AP-Pelvis radiograph at Year-2. These radiographs were analysed using a validated programme for measuring morphology. All morphological measurements were read blinded to outcome. At year 3 all participants were asked whether they experienced hip pain (side specific). This was repeated at visits up to and including 20-years. Logistic regression analysis (with robust standard errors and clustering by subject identifier) was performed using hip pain as a binary outcome. The model adjusted for baseline age, BMI and joint space and included only participants who were pain free on initial questioning.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 66 - 66
1 Jan 2013
Liddle A Pandit H Jenkins C Price A Dodd C Gill H Murray D
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Indications for Unicompartmental Knee Arthroplasty (UKA) vary between units. Some authors have suggested, and many surgeons believe, that medial UKA should only be performed in patients who localise their pain to the medial joint line. This is despite research showing a poor correlation between patient-reported location of pain and radiological or operative findings in osteoarthritis. The aim of this study is to determine the effect of patient-reported pre-operative pain location and functional outcome of UKA at one and five years.

Pre-operative pain location data were collected for 406 knees (380 patients) undergoing Oxford medial UKA. Oxford Knee Score, American Knee Society Scores and Tegner activity scale were recorded preoperatively and at follow-up. 272/406 (67%) had pure medial pain, 25/406 (6%) had pure anterior knee pain and 109/406 (27%) had mixed or generalised pain. None had pure lateral pain. The primary outcome interval is one year; 132/406 patients had attained five years by the time of analysis and their five year data is presented.

At one and five years, each group had improved significantly by each measure (mean δOKS 15.6 (SD 8.9) at year one, 16.3 (9.3) at year five). There was no difference between the groups, nor between patients with and without anterior knee pain or isolated medial pain.

We have found no correlation between preoperative pain location and outcome. We conclude that localised medial pain should not be a prerequisite to UKA and that it may be performed in patients with generalised or anterior knee pain.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 22 - 22
1 Jan 2013
Mehmood S Pandit H Grammatopoulos G Athanasou N Ostlere S Gill H Murray D Glyn-Jones S
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Introduction

Solid or cystic pseudotumour is a potentially destructive complication of metal on metal (MoM) couples, usually needing revision surgery. However, complete clearance of the pseudotumour is unlikely at times. This prospective case-controlled study reports cases which had recurrence after revision surgery for pseudotumour related to metal on metal hip couples.

Methods

A total of 37 hips (33 MoM hip resurfacing and four big head MoM total hip arthroplasty (THA)) were revised for pseudotumour during the last 10 years. The patient demographics, time to revision, cup orientation, operative and histological findings were recorded for this cohort. Patients were divided into two groups - group R (needing re-revision for disease progression) and group C (control - no evidence of disease progression). Oxford hip scores (OHS, 0–48, 48 best outcome) were used to assess clinical outcome. The diagnosis of disease progression was based on recurrence of clinical symptoms, cross-sectional imaging, operative and histological findings.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 198 - 198
1 Jan 2013
Alvand A Jackson W Khan T Middleton R Gill H Price A Rees J
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Introduction

Motion analysis is a validated method of assessing technical dexterity within surgical skills centers. A more accessible and cost-effective method of skills assessment is to use a global rating scale (GRS). We aimed to perform a validation experiment to compare an arthroscopic GRS against motion analysis for monitoring orthopaedic trainees learning simulated arthroscopic meniscal repairs.

Methods

An arthroscopic meniscal repair task on a knee simulator was set up in a bioskills laboratory. Nineteen orthopaedic trainees with no experience of meniscal repair were recruited and their performance assessed whilst undertaking a standardized meniscal repair on 12 occasions. An arthroscopic GRS, assessing parameters such as “depth perception,” “bimanual dexterity,” “instrument handling,” and “final product analysis” was used to evaluate technical skill. Performance was assessed blindly by watching video recordings of the arthroscopic tasks. Dexterity analysis was performed using a motion analysis tracking system which measured “time taken,” “total path length of the subject's hands,” and “number of hand movements”.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 11 - 11
1 Sep 2012
Mehmood S Gill H Murray D Glyn-Jones S
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Introduction

Stem geometry is known to influence the outcome in THA; however it is unknown whether the material properties, stiffness in particular can influence the stem stability and outcome. The aim of this study was to measure the influence of stem material properties on micromotion and migration using Roentgen Stereophotogrammetric Analysis (RSA) system.

Methods

41 patients were implanted with a collarless polished tapered (CPT) femoral stem (Zimmer, Warsaw, Indiana), which was made of either cobalt-chromium (CoCr) (n=21) or stainless steel (n=20). RSA was used to measure dynamically inducible micromotion (DIMM: difference in stem position in going from double-leg stance (DLS) to single leg stance (SLS)), prosthesis bending (difference in the head-tip distance when going from DLS to SLS), and mean migration of the head, tip and the cement restrictor. DIMM and bending were measured at 3 months, migration at 6, 12 and 24 months. All analyses were carried out using SPSS for windows (v.15.0.0, Chicago. IL, USA). Results were reported as mean ± 95% confidence interval (CI) and regarded as significant when p < 0.05.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XL | Pages 200 - 200
1 Sep 2012
Van Der Straeten C De Smet K Grammatopoulos G Gill H
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INTRODUCTION

Metal-on-metal hip resurfacing arthroplasty (MoMHRA) is a surgical option in the treatment of end-stage hip disease. The measurement of systemic levels of metal ions gives an insight into the wear occurring and is advocated by regulatory bodies as routine practice in the assessment of resurfaced hips. However, the acceptable upper levels of Chromium (Cr) and Cobalt (Co) ions concentration with clinical significance still have to be established. The aim of this study is to address this issue in unilateral and bilateral resurfaced hips.

METHODS

453 patients with unilateral MoMHRA and 139 patients with bilateral MoMHRA at >12 months postoperative were retrospectively identified from an independent hip specialist's database. Routine metal ion levels were measured at last follow-up (ICPMS protocol). Radiological assessment included measurement of acetabular component orientation using EBRA, calculation of contact patch to rim (CPR) distance, and evaluation for any adverse X-ray findings. The cohort was divided into the well functioning group (Group A) and the non-well functioning group (Group B). A well functioning resurfacing gad to fulfil all of the following criteria (bilateral patients had to fulfil criteria for both hips): no patient reported hip complaints, no surgeon detected clinical findings, HHS> 95, CPR distance> 10mm, no abnormal radiological findings and no further operation scheduled. Upper levels (acceptable limits) of Cr/Co were considered to be represented by the top margin of the box-whisker plot [upper limit = 75th quartile value + (1.5 x interquartile range)] in Group A.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 213 - 213
1 Sep 2012
Ashmore A Beard D Price A Gill H
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Aims

Interest in soft tissue Radiostereometric Analysis (RSA) is rising. Previous authors have tried, with varying levels of success, to use this technique to analyse the intra-substance portion of anterior cruciate ligament (ACL) graft constructs. These methods were either prone to large amounts of marker migration, deemed unsuitable for in-vivo use or, where alternative markers such as stainless steel sutures were used, lost the inherent accuracy that made RSA an attractive tool in the first place. We describe a modification of tantalum marker balls that allows for a new method of secure fixation to soft tissue in order to accurately analyse stretch, displacement and, potentially, dynamic movement using RSA.

Methods

1.5 mm tantalum tendon markers were predrilled with 0.3 mm holes, allowing them to be sutured directly to soft tissue. Using a previously described ACL graft model, the amount of marker ball migration was then analysed using RSA after cyclical loading between 20 N and 170 N at 25 Hz for 225,000 cycles.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXII | Pages 21 - 21
1 Jul 2012
Monk A Grammatopoulos G Chen M Gibbons C Beard D Murray D Gill H
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A femoral head/neck ratio (HNR) of less than 1.27 is associated with an increased risk of arthritis. The aim of this study was to establish whether there is evolutionary evidence that the homonin, bipedal stance has led to alterations in HNR that predispose humans to osteoarthritis (OA).

Specimens provided by The Natural History Museums of London, Oxford and the Department of Zoology, University of Oxford were grouped according to gait pattern, HAKF (Hip and knee flexed), Arboreal (ability to stand with hip and knee joints extended) and homonin/bi-pedal. Specimens included those from Devonion, Triassic, Jurrasic, Cretaceous, Miocene, Paleolithic, Pleistocene periods to modern day. Three-dimensional skeletal geometries were segmented using CT images and HNR measurements were taken from coronal views. These were compared with the HNR of 119 asymptomatic human volunteers and 210 patients that had a hip joint replacement for primary OA.

Species of the HAKF group had the smallest HNR (1.10, SD:0.09). Species of the Arboreal group had significantly higher HNR (1.63, SD:0.15) in comparison to the Bipedal group (1.41, SD:0.04) (p=0.006), Human (1.33, SD:0.08) and the OA group (1.3, SD:0.09).

The range of movement associated with arboreal habitat caused an associated change in HNR. This study would suggest that the HNR peaked in the Miocene period with species that ambulated on both ground and trees. More recent homonin gait appears to have developed a smaller HNR and humans have the smallest amongst their close ancestors. Evolutionary theory would suggest that modern environmental pressures might pre-dispose future hominin evolution to OA, secondary to a further reduction in HNR.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIV | Pages 24 - 24
1 Jul 2012
Mehmood S Gill H Murray D Glyn-Jones S
Full Access

Stem geometry is known to influence the outcome in THA; however it is unknown whether the material properties, stiffness in particular can influence the stem stability and outcome. The aim of this study was to measure the influence of stem material properties on micromotion and migration using Roentgen Stereophotogrammetric Analysis (RSA) system.

41 patients were implanted with a collarless polished tapered (CPT) femoral stem (Zimmer, Warsaw, Indiana), which was made of either cobalt-chromium (CoCr) (n=21) or stainless steel (n=20). RSA was used to measure dynamically inducible micromotion (DIMM: difference in stem position in going from double-leg stance (DLS) to single leg stance (SLS)), prosthesis bending (difference in the head-tip distance when going from DLS to SLS), and mean migration of the head, tip and the cement restrictor. DIMM and bending were measured at 3 months, migration at 6, 12 and 24 months. All analyses were carried out using SPSS for windows (v.15.0.0, Chicago. IL, USA). Results were reported as mean ± 95% confidence interval (CI) and regarded as significant when p < 0.05.

Preliminary analysis showed that total head DIMM was significantly (p = 0.02) greater for CoCr (0.97mm ± 0.6mm) than stainless steel (0.27mm ± 0.6mm). The mean stem bending for CoCr was 0.08mm (± 0.06mm) and for stainless steel 0.15mm (± 0.06mm) (p =0.77). Both implants heads migrated posteriorly, medially and distally. The mean subsidence for the cobalt-chromium and stainless steel stems was 1.02mm (± 0.19mm) (p < 0.001) and 1.12mm (± 0.34mm) (p=0.001) (p= 0.07) at 24 months.

It was interesting to note that the dynamically induced micromotion was greater for the stiffer stem, however there were no differences in terms of overall migration, indicating that survival (in terms of loosening) should be the similar for both steel and CoCr versions of this implant.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 26 - 26
1 Mar 2012
Steffen R O'Rourke K Murray D Gill H
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In 12 patients, we measured the oxygen concentration in the femoral head-neck junction during hip resurfacing through the anterolateral approach. This was compared with previous measurements made for the posterior approach. For the anterolateral approach, the oxygen concentration was found to be highly dependent upon the position of the leg, which was adjusted during surgery to provide exposure to the acetabulum and femoral head. Gross external rotation of the hip gave a significant decrease in oxygenation of the femoral head. Straightening the limb led to recovery in oxygen concentration, indicating that the blood supply was maintained. The oxygen concentration at the end of the procedure was not significantly different from that at the start.

The anterolateral approach appears to produce less disruption to the blood flow in the femoral head-neck junction than the posterior approach for patients undergoing hip resurfacing. This may be reflected subsequently in a lower incidence of fracture of the femoral neck and avascular necrosis.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_II | Pages 13 - 13
1 Feb 2012
Steffen R Smith S Gill H Beard D McLardy-Smith P Urban J Murray D
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This study aims to investigate femoral blood flow during Metal-on-Metal Hip Resurfacing (MMHR) by monitoring oxygen concentration during the operative procedure.

Patients undergoing MMHR using the posterior approach were evaluated. Following division of fascia lata, a calibrated gas-measuring electrode was inserted into the femoral neck, aiming for the supero-lateral quadrant of the head. Baseline oxygen concentration levels were detected after electrode insertion 2-3cm below the femoral head surface and all intra-operative measures were referenced against these. Oxygen levels were continuously monitored throughout the operation. Data from ten patients are presented.

Oxygen concentration dropped most noticeably during the surgical approach and was reduced by 62% (Std.dev +/-26%) following dislocation and capsulectomy. Insertion of implants resulted in a further oxygenation decrease by 18% (Std.dev +/-28%). The last obtained measure before wound closure detected 22% (Std.dev +/-31%) of initial baseline oxygen levels. Variation between subjects was observed and three patients demonstrated a limited recovery of oxygen levels during implant insertion and hip relocation.

Intra-operative measurement of oxygen concentration in blood perfusing the femoral head is feasible. Results in ten patients undergoing MMHR showed a dramatic effect on the oxygenation in the femoral head during surgical approach and implant fixation. This may increase the risk of avascular necrosis and subsequent femoral neck fracture. Future experiments will determine if less invasive procedures or specific positioning of the limb can protect the blood supply to femoral neck and head.