Aims. Bacterial infection activates neutrophils to release neutrophil extracellular traps (NETs) in bacterial biofilms of periprosthetic joint infections (PJIs). The aim of this study was to evaluate the increase in NET activation and release (NETosis) and haemostasis markers in the plasma of patients with PJI, to evaluate whether such plasma induces the activation of neutrophils, to ascertain whether increased NETosis is also mediated by reduced DNaseI activity, to explore novel therapeutic interventions for NETosis in PJI in vitro, and to evaluate the potential diagnostic use of these markers. Methods. We prospectively recruited 107 patients in the preoperative period of
Purpose of the study: The aim of this work was to determine whether erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and alpha-1-antitrypsin (A1AT) levels are correlated significantly with early postoperative infectious complications after hip
Purpose: The indication for humeral or total shoulder prosthesis in patients with avascular osteonecrosis of the shoulder depends on the radiographic stage of the necrosis. The purpose of this study was to analyse the prognostic radiographic features enabling proper identification of the indications for humeral or total prostheses. Material and methods: This retrospective multicentric study included 53 shoulders operated on for prosthetic repair of avascular osteonecrosis. There were 20 men and 29 women, mean age 57 years. A humeral prosthesis was used in 34 cases and a total prosthesis in 19. Clinical assessment was based on the Constant score and the radiographic analysis used the Arlet and Ficat classification. Staging was II (n=4), III (n=16), IV (n=21) and V (n=12). Independently of the radiographic stage of necrosis, three characteristic groups were defined. Group 1 (19 shoulders) included necrosis without bony collapse of the humeral head. Group 2 (20 shoulders) included necrosis with bony collapse of the humeral head with preservation of the anatomic relations with the glenoid cavity. Group 3 (14 shoulders) included necrosis with bony collapse and impaction of the humeral head in the glenoid with medialisation of the humerus. Results: Preoperatively, presence of bony collapse was associated with decreased pain and motion score. Major joint stiffness was noted in group 3 (8). The humeral prosthesis gave similar results for groups 1 and 2 (Constant score 73 and 75.3). Less satisfactory results was the rule in group 3 (Constant score 51.6). There was a postoperative erosion of the glenoid cavity in 83% of the shoulders in group 3 versus 12.5% in group 1 and 17% in group 2. The total prosthesis optimised results despite persistence of a difference between groups 2 and 3 (Constant score 83 and 64 respectively). Discussion: Destabilisation of the glenohumeral joint by impaction of the humeral head against the glenoid cavity has an effect on the clinical result of the
The aim is: to point out, in respect of Italian case law trends, the concept and the boundaries of surgeon malpractice liability in evaluating and implanting new prosthesic materials. The surgeon is liable for damages caused by fraudulent intention or fault during his clinical and operating activity. In a civil perspective, it could be the result of either a breach of a contract or a tort, depending on the existing relationship between the surgeon and the patient; but in both case there might be a serious inexperience or a light imprudence or negligence to admit a fair compensation for damages. While in a criminal perspective, the personal injuries might be the result of a serious fault also in the area of imprudence and negligence to admit the application of criminal sanctions. Of course, personal liability of surgeon stands by vicarious liability of health unit. Civil sanctions are more effective than criminal sanctions, not only because they have a wider area of application, but also because they are more incisive in quantitative terms, considering the new guidelines on pecuniary and biological damages that make out, at the same time, a compensatory and punitive function. The surgeon, to be sure not to be affected by civil and criminal actions, might inform the patient about the operating features and the consequences of non operating, follow standardized protocols, use products and materials tested and certified by the most influential scientific literature, be care of post-operating effects and adopt all remedies and treatments that can eliminate or reduce post-operating risks, use the best and up-to-date techniques available. In any case he is not liable for unforeseeable events, even if they are in a causative relationship with surgical activity.
To assess the reliability of a biomimetic osteochondral scaffold Maioregen (Finceramica Faenza SpA, Faenza, Italt) as a salvage and joint-preserving procedure in the treatment of late stages of osteonecrosis of the knee. Nine active patients aged under 65 year presenting with clinical and radiological signs of SPONK were treated with a biomimetic osteochondral scaffold. All patients were clinically evaluated preoperatively and yearly with a minimum follow-up of 2 years. Subjective IKDC and Lysholm Knee Scale were used to assess clinical outcome. Pre-operative and post-operative pain was quantified with VAS scale. Activity level were evaluated pre-operatively and at follow-up according to Tegner Activity Scale.Purpose
Methods
Total temporomandibular joint (TMJ) replacements reduce pain and improve quality of life in patients suffering from end-stage TMJ disorders, such as osteoarthritis and trauma. Jaw kinematics measurements following TMJ arthroplasty provide a basis for evaluating implant performance and jaw function. The aim of this study is to provide the first measurements of three-dimensional kinematics of the jaw in patients following unilateral and bilateral
Despite the fact that uncemented cup and stems are specifically designed for dysplasia to recover the true acetabular region in Crowe IV and sometimes Crowe III additional surgical procedure are required. Purpose of the study is to analize surgical procedure and then reconstruction options on severe hip dysplasia.
64 cases were subjected to a greater trochanteric osteotomy. In 12 cases proximal femural shortening was associated. In 9 cases rotational abnormality and shortening were controlled with a distal femur osteotomy. 55 cases were treated by a shortening subtrochanteric osteotomy that allows corrections of any deformity. Only uncemented stems were used and in the majority of cases a specific device for displastic hip (Wagner Conus produced by Zimmer).
Despite this, the more promising outcomes are concerning shortening subtrochanteric osteotomy with uncemented stem but only early and mid-term data are available.
The primary etiology necessitating revision is aseptic loosening. According to the SOFCOT classification, the acetabular deficiency was grade IV 9 times, grade III 47 times, grade I or II 107 times. All the implanted acetabular components are SERF dual-mobility implants. This system consists of a metal back which can be HA-coated and Press Fit or cemented in a Kerboull cross or in a Novae Arm. The mobile-bearing insert which allows a dual articulation between the head and the metal back is of polyethylene. We implanted 119 HA-coated press-fit cups and cemented 44 dual-mobility cups in a support ring or in a Kerboull cross.
We reported 8 complications: 6 early dislocations and 2 acetabular revisions for secondary mobilisation of the cup.
With 4% dislocations at a mean follow-up of 56 months, the dual-mobility cup seems to provide high stability in revision hip surgery when other factors such as muscular deficiency, extended synovectomies, difficult implant placement, encourage an uncertain postoperative prosthetic stability. These results have to be compared to those of other systems such as constrained acetabular cups or tripolar cups.
From 1998 to July 2003 admissions for elective arthroplasty surgery in Derriford Hospital were nursed alongside other orthopaedic and general medical patients. Since August 2003 a policy of pre-operative MRSA screening and a unit reserved exclusively for MRSA-free joint replacement patients have been used. No transfers from other wards were allowed. Patients positive on screening underwent eradication and were admitted to a different ward where they received teicoplanin on induction (in addition to standard policy cephradine). All post-operative wound infections following THR & TKR were monitored (NINSS surveillance system). Infections within 3 months were recorded. A control of non-screened hip hemi-arthroplasty patients was used to ensure a departmental wide reduction in MRSA was not occurring. 1.9% MRSA carriage rate was detected over the study. Before screening, 0.59% of 3386 cases were acutely infected with MRSA. After institution of screening and a dedicated MRSA free unit, 0.10% of 1034 were acutely infected. This was a 6-fold decrease (p<0.05). The infection noted was in a patient treated outside the ringfenced unit on High Dependency. In fact the infection rate on the ringfenced unit was zero. MRSA infection in the control was statistically unchanged during this period. A policy of MRSA screening and an MRSA free joint replacement ward reduces the incidence of acute MRSA infections.Conclusion
Since Aug‘03 pre-operative MRSA screening &
a ward reserved exclusively for MRSA free joint replacement patients has been used. All postoperative wound infections within 3 months following THR &
TKR were monitored. Before screening, 0.59% of 3386 were acutely infected with MRSA. After institution of study policy, 0.10% of 1034, were infected with MRSA.. This was a 6 fold decrease (p<
0.05). The rate of MRSA infection in a control of hemiarthroplasties was unchanged during this period. A policy of MRSA screening &
an MRSA free joint replacement ward reduces the incidence of acute MRSA infections.
The use of implant biomaterials for
The surgical treatment of a secondary gonarthrosis caused by haemophilic arthropathy needs high quality in soft tissue balancing and accurate alignment in total knee arthroplasty (TKA), which are essential for good long-term results. Due to the early-onset severe arthropathy, haemophiliacs undergo
Post-surgical infections are still one of the most frequent adverse events in the
We performed a systematic literature review to define features of patients, treatment, and biological behaviour of multicentric giant cell tumour (GCT) of bone. The search terms used in combination were “multicentric”, “giant cell tumour”, and “bone”. Exclusion criteria were: reports lacking data, with only an abstract; papers not reporting data on multicentric GCT; and papers on multicentric GCT associated with other diseases. Additionally, we report three patients treated under our care.Aims
Methods
Introduction and Objectives: In this study we assessed the usefulness of preoperative urine cultures as a tool to prevent infections due to Gram negative microorganisms in patients undergoing
Aim. Prosthetic joint infections (PJI) due to Enterobacter cloacae are rare and often severe. The aim of this study is to describe cases with E. cloacae PJI. Method. We conducted a retrospective and a monocentric study in an orthopedic unit where complex bone and joint infections are managed. From 2012 to 2016, we included patients with PJI which perioperative samples were positive with E. cloacae. We collected background, clinical, biological and microbiological data of the current infection, surgical and medical treatment, and the outcome of these patients. Results. A total of twenty patients were included which 8 were male. Location was hip in 14 cases, knee in 5 cases and ankle in one case. The median time between arthroplasty and revision for infection was 3 years. Fourteen patients had at least two surgeries for previous PJI. The median time between the last surgery and the revision for E. cloacae infection was 31 days. Eleven patients were infected by extended-spectrum beta-lactamases (ESBL) strains. Most frequently, the antibiotics used were carbapenem in 9 cases, cefepim in 7 cases, a quinolone in 7 cases and fosfomycin in 4 cases. Infection was cured in 10 cases (50%) with a median time of follow-up of 24 months. Five patients had a recurrent infection, three due to Staphylococcus epidermidis, one to Staphylococcus epidermidis and Propionibacterium acnes and one to Escherichia coli. Four patients had a relapse of E. cloacae infection. One patient died from non-infectious cause (stroke). Conclusions. PJI infections due to E.cloacae usually occur early after the last
Aim. When a prosthetic joint infection (PJI) is suspected, guidelines recommend performing periprosthetic samples, at least one for histopathological examination and 3 to 6 for microbiological culture. The diagnosis of infection is based on the presence of neutrophil granulocytes whose number and morphology can be variable, resulting in definition of “acute” inflammation. The acute inflammation of periprosthetic tissue is supportive of infection. Since 2007, in our hospital, for all patients with suspected PJI who underwent surgery, from each sample taken by the surgeon, one part has been sent to the pathologist and the other one to the microbiologist. Our aim was to compare histopathological to microbiological results from samples taken intraoperatively at the same site. Method. We conducted a retrospective study including all surgeries for which at least one couple “histopathology-culture” was found. Exclusion criterion was a history of antimicrobial treatment 2 weeks prior the surgery. Results. From July 2007 to April 2015, 309 surgeries for suspected PJI were performed in 181 patients. Median age of the study population was 70 years, 60% of patients were male, 45% had a history of joint infection. The location of arthroplasty was knee in 50% of cases and hip in 46%, ankle and shoulder in 4%. Surgery was performed within one month after the last
PJI du to Enterobacter cloacae are rare and often severe. The aim of our study is to define the history of patients with such infections and their outcome. We conducted a retrospective monocentric study in an orthopedic unit where complex bone and joint infections are supported. From 2011 to 214 we selected patients with E. cloacae PJI based on data from the microbiology laboratory. In their files we collected information on their background, their medical and surgical history, antibiotics they received in the year before infection, the suspected portal of entry, the management and the outcome. Twelve patients were included, 7 male and 5 female. PJI was located to the hip in 8 cases, the knee in 3 cases and the ankle in one case. The average time between the placing of the first prosthesis and infection was 3 years. Eleven patients had one or more surgery for previous PJI. The average time elapsed since the last surgery was 30 days. Eleven patients had been treated with antibiotic combinations for at least 6 weeks, in the year before E cloacae infection. A portal of entry was identified only two times: urinary tract infection in one patient and catheter-related infection in one patient. Antibiotics the more often prescribed were carbapenems (n = 5) and cefepime (n = 4), each combined with quinolones (n =4) or fosfomycin (n = 3). Two patients required an additional debridement within an average of 18 days. Infectious outcome was favorable in 8 cases (67%) with a median duration of follow-up of 26 months. Two patients had a recurrent infection, one due to Streptococcus oralis and one to Candida albicans. One patient had a relapse of E cloacae infection. One patient died from unknown cause. PJI infections due to E.cloacae usually occur early after
Haemophilia is a lifelong inherited bleeding disorder characterized by spontaneous bleeding resulting in painful joint deformities. Even if
Introduction and purpose: To assess the long-term results of Coventry-type tibial osteotomies performed in our center. Materials and methods: This is a retrospective study. We carried out a review of 324 histories of Coventry-type osteotomies selected from a total of 76 with a mean follow-up of 12.9 years (minimum 5, maximum 25). We reviewed the patients’ preoperative assessment, postoperative assessment and last assessment or consultation before a total knee replacement. We also looked at the clinical evaluation of the patients’ pain, degree of arthritis on x-ray (Ahlbäck) and degree of postoperative correction obtained. Results: 76 cases. Mean age 57.9 years (range: 35–72). Radiological degree of arthritis: 36.8% slight; 57.9% moderate; 5.2% severe. We found that patients with slight arthritis at the end of follow-up (mean 12.5 years) had 71% of satisfactory results. Satisfactory results were seen in 50% of patients with moderate arthritis (mean follow-up 16 years). With reference to the degree of correction, patients with mild over-correction had better results (8–12° valgus), followed by those normally corrected (0–8° valgus). A total of 30 patients (41%) required TKR at the end of their evolution (mean period of 13 years to TKR). Conclusions: In spite of the advances of
Purpose of the study: Prevention of operative site infections (OSI) in orthopaedic surgery requires strict observation of validated practices during hospitalisation and in the operative theatre, review of morbidity and mortality, and surveillance of OSI. Certain intrinsic patient-related risk factors of OSI cannot be controlled without direct implication of the patient and the referring physician. Search for Staphylococcus aureus (SA) colonisation and bacteriuria should be done in the ambulatory setting, before hospitalisation. The purpose of this work was to evaluate the feasibility of a search for SA in the nasal swabs and urine samples in patients scheduled for prosthesis surgery. Material and methods: This was a prospective study on 335 patients who had a total hip arthroplasty (THA) or a total knee arthroplasty (TKA) from January 1, 2007 to December 31, 2008. Bacteriological tests were performed before hospitalisation. Before hospitalisation, the patient and the primary care physician were give information on the proper procedure for chemical decontamination. The results of these laboratory tests were analysed and OSI were followed. Results: Three hundred thirty-five patients (195 THA and 143 TKA) were included; the sex-ratio was 0.95 M/F. Sixty-one patients (18%) exhibited SA colonization, including two meticillin resistant strains. Urine samples were positive in 30/323 patients (9.3%). Three patients presented an early OSI: two infections of a revision THA and one infection of a revision TKA. Two of these patients had an SA infection, including one who was colonized and had applied the chemical decontamination protocol before hospitalization. Discussion: By treating bacteriuria before hospitalization, deferral of the scheduled operations could be avoided. Laboratories must run two sets of tests to search for both met-S and met-R SA, which in our experience was not always the case despite written prescriptions. Implementation of chemical decontamination of the nasal passages and skin before surgery requires a well-established cooperation between the primary care physician and the hospital. The three infections recorded in this series involved revision procedures, with a context of rheumatoid polyarthritis for two patients. Conclusion: Systematic screening for SA colonization in orthopaedic surgery remains a subject of debate, particularly concerning the cost-efficacy balance, but can be quite useful in certain situations such as revision or
Purpose of the study: We analysed the clinical and radiographic outcomes of 113 cemented total knee arthroplasties (TKA) with resurfaced patella implanted in 83 patients with rheumatoid arthritis who were reviewed 1 to 12 years after implantation. Mean follow-up was 5.86 years. All implants were posterior stabilised (HLS) implanted by one operator using the same procedure. Material and methods: One hundred seventy-two rheumatic arthritis patients underwent TKA from 1996 to 2007. At last follow-up, 68 could not be contacted, 11 had died, 9 declined review. The review was conducted in 2008 for 83 patients, 113 TKA. Female gender predominated (86.4%) and 29 patients (32.6%) had two TKA. Mean age at revision was 67.6 years. Results: Seventy patients (84.4%) were satisfied or very satisfied with their prosthesis. The knee score (IKS) improved from 31.58 (0–63) preoperatively to 86.21 (59–99) postoperatively; the function score (IKS) improved from 31.7 (0–100) preoperatively to 77.12 (0–100) postoperatively. The improvement was significant for both scores. Men preoperative flexion was 97 (35–125) versus 112.1 (30–130) postoperatively. Ten knees presented anterior pain at revision (8.8%). The postoperative femorotibial mechanical angle was 180.72 (173–192). The mean femoral mechanical angle was 91.3 (78–99); the mean tibial mechanical angle was 89.4 (52–110). Men postoperative patellar height was 0.79 (0.24–2) measured with the Blackburn index. The patella was centred for 87.6% (99 knees) and subluxated laterally for 12.1% (14 knees). There were no loosening. Two arthroplasties had to be revised surgically (1.8%): one for infection (two-phase replacement with a hinged prosthesis) and one for patellar fracture treat by osteosynthesis. Two patients developed a postoperative phlebitis (2.4%). Discussion: This study demonstrates the good mid-term outcomes achieved with a cemented posterior stabilised TKA in patients with rheumatoid arthritis. These results are nevertheless slightly less satisfactory than with TKA implanted for degenerative disease: this might be explained generally by disease-related impact on the functional result.
Surgical site infection (SSI) is an important outcome indicator. It is estimated that 70% of post-operative infections present after discharge. A reliable post-discharge surveillance (PDS) method is yet to be described. The aim of this prospective cohort study was to assess the reliability of patient self-diagnosis. Telephone questionnaires were used following hip and knee
Introduction: Surgical site infection is a growing and expensive complication. Surgical site surveillance is performed with the aid of laboratory tests and clinical evaluation; the latter has some limits, including reproducibility and validation of results and, as suggested by many authors, the need of a dedicated well trained staff. At present no imaging instruments are available for routine objective monitoring of “normal” or complicated surgical site healing. Recently, technological improvement made available for clinical use high resolution portable digital telethermocameras at relatively low-costs. No data are available in the literature, concerning the “physiological” thermographic pattern of surgical wounds in orthopaedics. The aim of this study is then to evaluate the physiological telethermographic pattern of surgical site healing after hip and knee
Culture of tissue samples obtained peri-operatively is ‘the gold standard’ for determining the presence of infection in prosthetic revision surgery. The growth of identical bacterial strains in three or more specimens strongly indicates an infected prosthesis. With routine microbiological culture techniques, identification of different phenotypes of coagulase negative staphylococcus (CNS) will be interpreted as either contamination or a polybacterial infection. At our clinic, different phenotypes of CNS are cultured in approximately 20% of patients operated with a two-stage revision due to a chronic prosthetic infection. We studied the genotype of different phenotypes of CNS cultured in specimens obtained from prosthetic joints. We analysed 22 cases, where different phenotypes of CNS were cultured in tissue, and joint fluid specimens were collected peri-operatively. The pre-operative diagnosis was chronic prosthetic infection (n=16), aseptic revision (n=5) and primary prosthesis (n=1). Different phenotypes were assessed by colony morphology and/or antibiogram. Pulsed-field gel electrophoresis (PFGE) was employed to identify and compare the genotypes. In 16 out of 22 cases (73 %), PFGE unveiled that phenotypically different strains of CNS belonged to the same genotype. Of these 16 cases 7 had different antibiograms. In the other group (6/22), phenotypically different strains of CNS did not belong to the same genotype. In the 16 cases with different phenotypes belonging to the same genotype, gentamicin bone cement had previously been used in 15 cases. In the other group (6/22), gentamicin bone cement had not been used previously in any case (p <
0.01, chi-square test). Phenotypically different strains of CNS identified by routine microbiological techniques should not be classified readily as contamination or as a mixed bacterial infection in
Systematic and prospective collection of data (Registro degli Interventi di Protesi d’Anca – RIPA-L) on hip replacement operations is underway in the Lazio Region (Italy) as part of a multi-regional registry on orthopaedic
Introduction and purpose: There has been a great increase in
Low virulent chronic prosthetic infection might be indistinguishable to aseptic loosening. Polymerase chain reaction (PCR) has been introduced to improve bacterial detection of implant infection. However, there is great risk of false positive results when using broad range/universal PCR primers. The source of DNA contaminants may be of environmental origin as well as the reagents employed. To study the presence of bacterial DNA in culture negative biopsy specimens by using defined criteria for PCR positivity. We included six specimens from each of 21 patients preoperatively considered having aseptic loosening of a hip prosthesis. These 126 specimens were culture negative after seven days of incubation. Prior to incubation, the specimens were divided, and half of each specimen was processed for PCR. Three sets of primer pairs targeting the 16S rRNA gene were developed. Nine specimens from culture proven prosthetic infections and nine specimens from primary
Introduction: With the growing number of primary knee arthroplasties, the number of revision operations is also increasing. The large number of unicondylar replacements carried out in the 1980’s, due to lack of modern total condylar implants, grant the revision techniques an outstanding significance in Hungary. One of the main issues of modern revision techniques is the management of bone defects, which can be solved by different methods documented in literature. Aim of study: The aim of our study was to investigate the success and feasibility of the various defect management techniques by evaluating the results of revision knee
To evaluate safety outcomes and patient satisfaction of the re-introduction of elective orthopaedic surgery on ‘green’ (non-COVID-19) sites during the COVID-19 pandemic. A strategy consisting of phased relaxation of clinical comorbidity criteria was developed. Patients from the orthopaedic waiting list were selected according to these criteria and observed recommended preoperative isolation protocols. Surgery was performed at green sites (two local private hospitals) under the COVID-19 NHS contract. The first 100 consecutive patients that met the Phase 1 criteria and underwent surgery were included. In hospital and postoperative complications with specific enquiry as to development of COVID-19 symptoms or need and outcome for COVID-19 testing at 14 days and six weeks was recorded. Patient satisfaction was surveyed at 14 days postoperatively.Aims
Methods
Shoulder arthroplasty has been performed by many years for the treatment of several conditions such as osteoarthritis, umeral head avascular necrosis and proximal umeral fractures following traumas. Surgical site infection (SSI) following shoulder arthroplasty remains a challenge, which increases morbidity including reoperations, implant removal, poor mobility, and raises extra medical costs. Identification of risk factors may help implementing adequate strategies to prevent infection. We aim to identify pre- and intra-operative risk factors associated with deep infections in shoulder arthroplasty. An age and sex-matched case control study was conducted to describe the prevalence rate, clinical and microbiological findings and to evaluate patient and surgical risk factors for shoulder arthroplasty-associated infections (SAIs), among 158 patients who underwent shoulder replacement surgery due to any reason, from 1988 to 2011 at a tertiary public university institution. To evaluate risk factors from SAI we performed uni- and multivariate analysis by multiple logistic regression. We analyzed 168
Great diffusion of hip
Purpose of the study: Increasing the number of times the operating room doors open increases the number of airborne bacteria and consequently the rate of postoperative infections with sometimes disastrous results, particularly for prosthesis surgery. Material and methods: An observer counted the number of times the door to the operating room were opened during orthopaedic operations. The study was conducted in a teaching hospital (hospital A) during scoliosis surgery then repeated for a similar operation after posting dissuasive signs and delivery of information to the personnel concerning the risk of contaminating the patient. A study was then conducted for total hip arthroplasty (THA) in another teaching hospital (hospital B) and in a private clinic (hospital C). The same protocol as used in South Australia was applied for these studies. Results: The mean rate of door opening in hospital A was 0.52/min. This rate was 0.45/min (13.5% less) in the same hospital A after posting dissuasive signs on the doors and providing information to the personnel. In hospital B, the rate was 0.67/min. In hospital C, the rate was 0.42/min (i.e. 37% less). In Australia, the mean rate was 1/min in hospital A before sign posting and information delivery and 0.65 (−35%) after. In hospital B, the rate was 0.87/min and in hospital C 0.47/min (i.e. 46% less). Discussion: Nearly 50 years ago Sir John Charnley demonstrated that airborne contamination must be controlled in
Introduction:
Introduction:
Aim: To determine the surgical site infection (SSI) rates for prosthetic hip and knee replacement surgery. Materials and Methods: Between April 2002 and March 2003 the Infection Control team in conjunction with the Orthopaedic Department had participated in national surveillance project to determine the surgical site infection rates for prosthetic hip and knee replacement surgery. Information was collected relating to surgeon specific data and patient risk index. Each surgeon was given a unique confidential code and patients intrinsic risk of infection calculated based on ASA grade, wound class and the duration of surgery. Results: During the first year of surveillance 455 prosthetic hip replacements were undertaken (i.e. hemiarthroplasty, primary and revision surgery). A total of 12 patients were identified with an SSI giving an average of 2.6% compared with national figure of 3.0%. Out of this 25% (3) superficial and 75%(9) deep-seated infection with Methicillin Sensitive Staphylococcus Aureus (MSSA) and MRSA being the commonest organisms. 234 prosthetic knee replacements (Primary and Revisions) were carried out over the same period of time with 7 cases identified with SSI, an average incidence of 3% compared with national average of 1.6%. Three were superficial and four with deep infection with MRSA, MSSA and coagulase negative staphylococci being the commonest organisms. MRSA containment policy was introduced in November 2002 with pre operative screening,” ring fencing” orthopaedic patients and improved awareness of cross infection. Since then over the last 4 months of this study the incidence of SSI has fallen from 3.3% to 1.9% in
Introduction: Antibiotic prophylaxis is a standard practice in
Purpose: Hip joint involvement is a frequent complication of Paget’s disease. We conducted a multicentric retrospective study to analyse perioperative problems and outcome after total hip arthroplasty in patients with Paget’s disease. Material and methods: Thirty-nine total hip arthroplasties were implanted between 1979 and 1998 in 35 patients with Paget’s disease of the hip (four bilateral cases). The series included 20 men and 15 women, mean age 74 years (55–86). The pre and postoperative status was evaluated with the Harris score and radiographically. We recorded operative time, blood loss, and events noted in the operative report. Among the 35 patients, 24 were retained for analysis (three deaths, eight lost to follow-up) at mean 62 months. Results: The mean preoperative Harris score was 46/100 (18–67). Eighteen patients had leg length discrepancy. Nine had permanent hip flexion associated with external rotation and seven had coxa vara. Twenty-nine patients were given anti-osteoclastic treatment preoperatively. We implanted 20 cemented cups and 19 press-fit cups. Thirty-one femoral stems were cemented and eight were not. On average, operative time was 130 minutes and blood loss was 830 cc. Difficult operative events involved luxation of the femoral head, remodelled sclerous bone (greater trochanter fractures, difficult reaming, narrow canal), cam effect related to bone hypertrophy and bleeding. Venous thrombosis occurred in four patients, pulmonary embolism in one, and one psoas haematoma. There were three luxations. At last follow-up (mean 71 months), the clinical outcome was excellent for 13 patients (48%), good for eight (29%), fair for two (7%) and poor for four (15%). Implants were cemented at the pelvis and femur level in three cases and noncemented in one. Discussion:
Purpose:
Aim: To see the efficacy of white cell scan in the diagnosis of prosthetic joint infections. Materials and methods: A retrospective study was done from Jan 2001 to Dec 2003 on patients with suspected joint infections after
Implant-related infection is one of the most devastating complications in orthopaedic surgery. Many surface and/or material modifications have been developed in order to minimise this problem; however, most of the We describe a method for the study of bacterial adherence in the presence of preosteoblastic cells. For this purpose we mixed different concentrations of bacterial cells from collection and clinical strains of staphylococci isolated from implant-related infections with preosteoblastic cells, and analysed the minimal concentration of bacteria able to colonise the surface of the material with image analysis.Objectives
Methods
Our aim was to analyse the long-term functional outcome of two
forms of surgical treatment for active patients aged >
70 years
with a displaced intracapsular fracture of the femoral neck. Patients
were randomised to be treated with either a hemiarthroplasty or
a total hip arthroplasty (THA). The outcome five years post-operatively
for this cohort has previously been reported. We present the outcome
at 12 years post-operatively. Initially 252 patients with a mean age of 81.1 years (70.2 to
95.6) were included, of whom 205 (81%) were women. A total of 137
were treated with a cemented hemiarthroplasty and 115 with a cemented
THA. At long-term follow-up we analysed the modified Harris Hip
Score (HHS), post-operative complications and intra-operative data
of the patients who were still alive.Aims
Patients and Methods
In this case study, we describe the clinical
presentation and treatment of 36 patients with periosteal chondrosarcoma
collected over a 59-year period by the archive of the Netherlands
Committee on Bone Tumours. The demographics, clinical presentation,
radiological features, treatment and follow-up are presented with
the size, location, the histological grading of the tumour and the
survival. We found a slight predominance of men (61%), and a predilection
for the distal femur (33%) and proximal humerus (33%). The metaphysis
was the most common site (47%) and the most common presentation
was with pain (44%). Half the tumours were classified histologically
as grade 1. Pulmonary metastases were reported in one patient after
an intra-lesional resection. A second patient died from local recurrence
and possible pulmonary and skin metastases after an incomplete resection. It is clearly important to make the diagnosis appropriately because
an incomplete resection may result in local recurrence and metastatic
spread. Staging for metastatic disease is recommended in grade II
or III lesions. These patients should be managed with a contrast-enhanced MRI
of the tumour and histological confirmation by biopsy, followed
by Cite this article:
The credibility and creativity of an author may be gauged by the number of scientific papers he or she has published, as well as the frequency of citations of a particular paper reflecting the impact of the data on the area of practice. The object of this study was to identify and analyse the qualities of the top 100 cited papers in orthopaedic surgery. The database of the Science Citation Index of the Institute for Scientific Information (1945 to 2008) was used. A total of 1490 papers were cited more than 100 times, with the top 100 being subjected to further analysis. The majority originated in the United States, followed by the United Kingdom. The top 100 papers were published in seven specific orthopaedic journals. Analysis of the most-cited orthopaedic papers allows us a unique insight into the qualitites, characteristics and clinical innovations required for a paper to attain ‘classic’ status.
The aim of this study was to analyse the functional outcome after a displaced intracapsular fracture of the femoral neck in active patients aged over 70 years without osteoarthritis or rheumatoid arthritis of the hip, randomised to receive either a hemiarthroplasty or a total hip replacement (THR). We studied 252 patients of whom 47 (19%) were men, with a mean age of 81.1 years (70.2 to 95.6). They were randomly allocated to be treated with either a cemented hemiarthroplasty (137 patients) or cemented THR (115 patients). At one- and five-year follow-up no differences were observed in the modified Harris hip score, revision rate of the prosthesis, local and general complications, or mortality. The intra-operative blood loss was lower in the hemiarthroplasty group (7% >
500 ml) than in the THR group (26% >
500 ml) and the duration of surgery was longer in the THR group (28% >
1.5 hours Because of a higher intra-operative blood loss (p <
0.001), an increased duration of the operation (p <
0.001) and a higher number of early and late dislocations (p = 0.002), we do not recommend THR as the treatment of choice in patients aged ≥ 70 years with a fracture of the femoral neck in the absence of advanced radiological osteoarthritis or rheumatoid arthritis of the hip.
We studied retrospectively the results of revision arthroplasty of the elbow using a linked Coonrad-Morrey implant in 23 patients (24 elbows) after a mean follow-up period of 55 months. According to the Mayo Elbow Performance Score, 19 elbows were satisfactory, nine were excellent and ten good. The median total score had improved from 35 points (20 to 75) before the primary arthroplasty to 85 points (40 to 100) at the latest follow-up. There was a marked relief of pain, but the range of movement showed no overall improvement. Two patients had a second revision because of infection and two for aseptic loosening. The estimated five-year survival rate of the prosthesis was 83.1% (95% confidence interval 61.1 to 93.3). Revision elbow arthroplasty using the Coonrad-Morrey implant provided satisfactory results but with complications occurring in 13 cases.
We wished to estimate the incidence of surgical-site infection (SSI) after total hip replacement (THR) and hemiarthroplasty and its strength of association with major risk factors. The SSI surveillance service prospectively gathered clinical, operative and infection data on inpatients from 102 hospitals in England during a four-year period. The overall incidence of SSI was 2.23% for 16 291 THRs, 4.97% for 5769 hemiarthroplasty procedures, 3.68% for 2550 revision THRs and 7.6% for 198 revision hemiarthroplasties.