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Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 3 - 3
1 Feb 2020
Hartwell M Sweeney RHP Marra G Saltzman M
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Background

Rotator cuff atrophy evaluated with computed tomography scans has been associated with asymmetric glenoid wear and humeral head subluxation in glenohumeral arthritis. Magnetic resonance imaging has increased sensitivity for identifying rotator cuff pathology and has not been used to investigate this relationship. The purpose of this study was to use MRI to assess the association of rotator cuff muscle atrophy and glenoid morphology in primary glenohumeral arthritis.

Methods

132 shoulders from 129 patients with primary GHOA were retrospectively reviewed and basic demographic information was collected. All patients had MRIs that included appropriate orthogonal imaging to assess glenoid morphology and rotator cuff pathology and were reviewed by two senior surgeons. All patients had intact rotator cuff tendons. Glenoid morphology was assigned using the modified-Walch classification system (types A1, A2, B1, B2, B3, C, and D) and rotator cuff fatty infiltration was assigned using Goutallier scores.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_7 | Pages 43 - 43
1 May 2016
Bischoff J Wernle J Marra G Verborgt O
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Introduction

Good outcomes in reverse shoulder arthroplasty (RSA) rely in part on stability of the humeral component. Traditionally humeral components have been cemented, however there has been recent interest in press-fit fixation of humeral components in RSA. Lateralization of the head center in RSA can impart larger moments on the humeral component than for anatomic reconstructions, increasing the importance of distal humeral canal preparation for implant stability. To date, the primary stability of any type of press-fit humeral prosthesis has been largely unexplored. The goal of this study is to evaluate the effect of over-reaming the distal humeral canal in a press-fit humeral component in RSA.

Methods

Computed tomography (CT) data of the shoulder were obtained from 55 shoulders. Images were segmented to produce digital models of the humerus. Humeral components for RSA (2mm diameter size increments) were sized and placed per the surgical technique, including preparation of the humerus with the appropriate reamers (1mm increments). Finite element models for each specimen were created with heterogeneous bone properties derived from the CT scan. Pressfit between the bone and stem was resolved to quantify the initial contact pressure on the stem; each stem was then loaded at 566N oriented 20° lateral and 45° anterior. Overall motion of the stem was measured, as well as interfacial micromotion in the porous coating region (Fig. 1). The effect of line-to-line (L2L) reaming and over-reaming by 1 mm was evaluated using an unpaired Student's t-test, with significance defined at p<0.05.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 1 - 1
1 Mar 2010
Williams D Wojewnik B Tonino P Mikolyzk D Callaci J Himes R Wei A Magovern B Volkmer D Wezeman FH Marra G
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Purpose: To determine if administration of recombinant bFGF in an alginate gel would increase early healing mechanical parameters in acutely injured rat rotator cuff tendon at specific time points.

Method: Sprague Dawley rats were randomly divided into 2 groups and had surgically created 1mm (half tendon width) full thickness injuries at exactly 2mm from insertion site of Infraspinatus on the humerus. 200ng of bFGF or vehicle control was administered to randomly chosen rats. Tendons were harvested at 1 week, 2 weeks and 4 weeks. In both groups, the Infraspinatus tendon was dissected, and left attached to the humerus. At the time of testing, the intact portion of the injured tendon was divided sharply across tendon fibers at the level of the injury leaving only the healing tissue callus in continuity with the remaining proximal and distal portions of the tendon and loaded to failure.

Results: At 1 week the injury group’s average load to failure was 0.60N versus 0.61N in the bFGF injury group P = 1.000. At 2 weeks the injury group’s average load to failure increased to 1.03N versus 2.08N in the bFGF injury group P = 0.440 At 4 weeks the injury group’s average load to failure increased to 3.93N versus 5.56N in the bFGF injury group P = 0.008 representing a 41% increase in ultimate load. At 4 weeks, callus size of the injury group was 0.4mm2 versus 2.7mm2 in the bFGF injury group P < 0.001. Stiffness at 4 weeks for the injury tendons was 2.15 N/mm versus 3.54 N/mm in the bFGF group P = 0.008.

Conclusion: At 4 weeks healing tissue of acutely injured rotator cuff exposed to bFGF has an increase in ultimate load to failure (41% compared to control), increase in tendon callus size and stiffness. Our findings suggest a role of bFGF or similar growth factors in accelerating the healing of injured rotator cuff tendon.