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Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_11 | Pages 33 - 33
1 Jul 2014
A COMPETITIVE ASSAY FOR BACTERIAL AND CELLULAR ADHERENCE TO BIOMATERIALS: AN IN VITRO APPROACH TO THE “RACE FOR THE SURFACE” THEORY
Perez-Jorge C Perez-Tanoira R Lozano D Conde A Arenas M Hernandez-Lopez J De-Damborenea J Gomez-Barrena E Esbrit P Esteban J
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Summary Statement

Description of an original in vitro protocol for assessing combined bacteria and cell competitive adherence on the surface of biomaterials of medical interest

Objectives

Biomaterial-related infections are a major clinical problem. The pathogenesis of this syndrome has been described as a competitive adherence between bacteria and human cells in the so-called “race for the surface” theory. The aim of this study is to develop an in vitro protocol method that can be used to investigate this competence and its implications in the development of materials aimed to be used in orthopedic surgery.