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Orthopaedic Proceedings
Vol. 97-B, Issue SUPP_16 | Pages 135 - 135
1 Dec 2015
Chaturvedi A Barlow G Sharma H
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The management of chronic osteomyelitis is fraught with difficulties; a multi-disciplinary team approach is recommended for optimum outcome. Thorough debridement, dead space management and organism targeted antibiotic therapy the gives best clinical results. Calcium sulphate beads impregnated with antibiotic is an absorbable option for prolonged local antibiotic elution and dead space management.

This study aims to analyse the early results of single stage management of osteomyelitis with antibiotic impregnated calcium sulphate beads. Following surgical debridement, calcium sulphate impregnated typically with tobramycin and/or vancomycin is inserted to obliterate the dead space. Intravenous antibiotics – typically teicoplanin and piperacillin-tazobactam – are administered until culture results permit rationalisation to narrow spectrum agents. Patients are followed up in Infectious Diseases and Orthopaedic clinics for a period of 12 months and discharged if quiescence is achieved.

We conducted a retrospective analysis of our prospective database to identify patients treated with our single stage protocol for chronic osteomyelitis. We excluded patients that had (1) less than 6 months of follow up, (2) incomplete metal-ware removal, (3) patients lost to follow up. Fourteen patients (9 men, 5 women) with mean age of 41 (16–73) years and mean follow up of 9 (6–12) months were included in study. Eleven patients had previous surgeries involving internal fixation; the rest were primary osteomyelitis. Seven patients had washouts and removal of metal-ware procedures for osteomyelitis prior to referral to the bone infection service. Clinical, radiographic, and laboratory (microbiological, biochemical and haematological) methods were used to monitor response to treatment.

Cierney-Mader classification determined that 8 patients were classed as type A (normal hosts); 4 as BS (systemically compromised); 2 as BLS (locally and systemically compromised). Anatomic analysis suggested 7 were Type 1 (medullary osteomyelitis); the remaining 7 were type 3 (localised disease). Five patients were staged IA; three each staged IIIA and IIIBS; and one each staged IBs, IBLS, IIIBLS.

Staphylococcus Aureus was the commonest causative organism.

Follow up radiograph monitoring indicated absorption of the beads by 3 months.

There has been no evidence of recurrence based on clinical, radiographic and blood based parameters in all patients.

Short-term results of single stage osteomyelitis treatment with calcium sulphate beads impregnated with antibiotics are promising.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_7 | Pages 6 - 6
1 Feb 2013
Chaturvedi A Hadland Y Sharma H
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Introduction

The Ilizarov (IF) and Taylor Spatial (TSF) external fixator frames are commonly used to manage complex fractures and bone deformities and a dedicated Frame Service Team at our unit supports patients during pre- and post-operative period. Few studies have assessed the satisfaction of patients who have been treated with Circular frames.

Methods

A questionnaire was designed and distributed to 56 consecutive patients treated with a circular frame. Data was collected prospectively. Questions were focused on information given pre op, during treatment, overall satisfaction with the frame, morbidity and areas in which the frame service could be improved.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_7 | Pages 3 - 3
1 Feb 2013
Sivasankaran K Chaturvedi A Madhu T Hadland Y Sharma H
Full Access

AIM

To study the incidence of thromboembolism among patients treated with ring fixators in lower limb injuries and their risk factor association.

METHODS & MATERIALS

Notes of 180 (130 men & 50 women) patients treated with circular frame were retrospectively studied. Risk factors for thromboembolism as advised by NICE were recorded and scored. The duration of pre-operative limb immobilisation, hospital stay and duration of frame, were also recorded.