Advertisement for orthosearch.org.uk
Results 1 - 3 of 3
Results per page:
Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_16 | Pages 88 - 88
19 Aug 2024
Kendall J Forlenza EM DeBenedetti A Levine BR Valle CJD Sporer S
Full Access

An intra-articular steroid injection can be a useful diagnostic tool in patients presenting with debilitating hip pain and radiographically mild osteoarthritis. The clinical and patient reported outcomes associated with patients who have radiographically mild osteoarthritis and undergo total hip arthroplasty (THA) remain poorly studied.

Patients undergoing primary, elective THA at a single academic medical center by a fellowship-trained adult reconstruction surgeon between 2017–2023 were identified. Only those patients who underwent an intra-articular corticosteroid injection into the operative hip within one year of surgery were included. Patients were divided into two cohorts based on the severity of their osteoarthritis as determined by preoperative radiographs; those with Kellgren-Lawrence (KL) grade I-II arthritis were classified as “mild” whereas those with KL grade III-IV arthritis were classified as “severe”. Clinical and patient reported outcomes at final follow-up were compared between cohorts.

The final cohorts included 25 and 224 patients with radiographically mild and severe osteoarthritis, respectively. There were no baseline differences in age, gender or time between intra-articular corticosteroid injection and THA between cohorts. There were no significant differences in the preoperative or postoperative HOOS JR values between patients with mild or severe arthritis (all p>0.05). There were no significant differences in the change in HOOS JR scores from the preoperative to final follow-up timepoints between cohorts. There were no significant differences in the percentage of patients who achieved the minimal clinically important difference (MCID) on the HOOS JR questionnaire between cohorts.

Patients with radiographically mild osteoarthritis who feel relief of their hip pain following an intra-articular corticosteroid injection report similar preoperative debility and demonstrate similar improvements in patient reported outcome scores following THA compared to patients with radiographically severe osteoarthritis.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_11 | Pages 7 - 7
1 Aug 2018
Calkins T Culvern C Nam D Gerlinger T Levine B Sporer S Della Valle C
Full Access

The purpose of this randomized controlled trial is to evaluate the efficacy of using dilute betadine versus sterile saline lavage in aseptic revision total knee (TKA) and hip (THA) arthroplasty to prevent acute postoperative deep periprosthetic joint infection (PJI).

Of the 450 patients that were randomized, 5 did not have 90-day follow-up, 9 did not receive the correct treatment, and 4 were excluded for intraoperative findings consistent with PJI. 221 Patients (144 knees and 77 hips) received saline lavage only and 211 (136 knees and 75 hips) received a three-minute dilute betadine lavage (0.35%) prior to wound closure. Patients were observed for the incidence of acute postoperative deep PJI within 90 days of surgery. Statistical analysis was performed using t-tests or Fisher's exact test where appropriate. Power analysis determined that 285 patients per group are needed to detect a reduction in the rate of PJI from 5% to 1% (alpha=0.05, beta=0.20).

There were seven PJIs in the saline group and one in the betadine lavage group (3.2% vs. 0.5%, p=0.068). There were no significant differences in any baseline demographics between groups suggesting appropriate randomization.

Although we believe the observed difference between treatments is clinically relevant, it was not statistically significant with the sample size enrolled thus far and enrollment is ongoing. Nonetheless, we believe that these data suggests that dilute betadine lavage is a simple method to reduce the rate of acute postoperative PJI in patients undergoing aseptic revision procedures.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 10 - 10
1 Jan 2018
Sheth N Melnic C Brown N Sporer S Paprosky W
Full Access

The treatment of severe acetabular bone loss is challenging, especially in the setting of an associated chronic pelvic discontinuity. There are several available treatment options for chronic pelvic discontinuity, each of which has its own disadvantages. One of the major difficulties with this entity, regardless of the reconstructive technique chosen, is the inability to obtain reproducible healing of the discontinuity. We evaluated the use of acetabular distraction, a technique which achieves peripheral or lateral distraction and central or medial compression across the discontinuity. We recommend acetabular distraction to allow for implantation of a stable construct, achieve biologic fixation and increase the likelihood of discontinuity healing.

In this multi-center trial, 32 patients that underwent acetabular revision for a chronic pelvic discontinuity using acetabular distraction were radiographically evaluated at a minimum of 25 months (range, 25 to 160 months). The study cohort was categorized according to the Paprosky acetabular bone loss classification: seven (22%) type IIC, five (16%) type IIIA, and 20 (62%) type IIIB defects. Fourteen (70%) of the 20 patients with a type IIIB acetabular bone loss pattern required use of augments for acetabular reconstruction.

Of the 32 patients, 1 (3%) patient required a revision for aseptic loosening, 2 (6%) patients had evidence of radiographic loosening but were not revised, and 3 (9%) patients had migration of the acetabular component into a more stable position. Radiographically, 22 (69%) of the cohort demonstrated healing of the discontinuity. The Kaplan-Meier construct survivorship was 83.3% when using aseptic acetabular loosening as an end-point.

During this study, the authors created a new pelvic discontinuity classification based on the type of reconstruction required. The classification mirrors the Paprosky acetabular bone loss classification. A Type I chronic pelvic discontinuity required jumbo cup reconstruction without augments. A type II discontinuity required the use of an augment for an extracavitary defect. A type III discontinuity required an augment for an intracavitary defect.

Type III defects were further subdivided into type IIIA and IIIB discontinuity. Type IIIA discontinuities utilized an augment to reconstruct the anterosuperior and/or posteroinferior column defect for primary stability of the overall construct. Type IIIB discontinuities utilized augments to reconstruct the anterosuperior and/or posteroinferior column defect for primary stability as well as a posterosuperior augment for supplemental fixation. All augments were unitized to the cup with cement. Type IV defects were massive defects that required the use of two orange-slice augments, secured together with screws and placed centrally to restore the defect, and a cup implanted and unitized to the augments with cement.

According to this new classification, the discontinuity reconstructions in our study were classified as follows: 12 (38%) type I, 8 (25%) type II, 6 (19%) type IIIA, 6 (19%) type IIIB, and 0 as type IV. Acetabular distraction technique demonstrates favorable radiographic outcomes with reproducible discontinuity healing in a majority of cases. This alternative technique allows for biologic fixation and intra-operative customization of the construct to be implanted based on the bone loss pattern present following component removal.