Anterior cruciate ligament reconstruction has been traditionally performed as an inpatient due to post-operative analgesic requirements. Increased patient demands and pressures of bed shortages have led to the development of day case surgery. Day case anterior cruciate ligament (ACL) reconstruction surgery using an analgesic pump was assessed. 24 consecutive ACL reconstructions using arthroscopic hamstring technique were performed as day case procedures. All received a standard anaesthetic of propofol, fentanyl, tenoxicam, and morphine. And an intra-articular administration of 10mls 0. 75% Ropivicaine Hydrochloride at the end of surgery. 0. 2% Ropivicaine at a rate of 2mls/hr was infused over 48hrs using a compression spring infusion pump (Pain Control Infusion Pump – Sgarlato Labs) via an intraarticular catheter. Post operative pain was assessed by a Visual Analogue Score (VAS) recorded by the patient onto an unmarked 1 Ocin line (0 – no pain ; 1 0 – maximum pain) For the 48hrs the pump was infusing the average VAS was 2. 7 with minimal additional analgesia required. Following pump removal by a District Nurse, the average VAS score was 1. 9 with similar analgesia requirements All patients were satisfied with their care; none had problems related to the use of or removal of the pump; none required re-admission or review from their GP; or suffered post-operative complications. The cost for day case surgery was 260 (including theatre time; pump and drug costs; District Nurse costs) compared to 1072 for an average in-patient stay of 4 days (both exclude ACL specific implants, surgeon and anaesthetist costs). The intra-articular infusion of local anaesthetic has been shown to be well received by patients with no additional risks. It is an effective and cost-effective means of providing post-operative analgesia allowing day case ACL Reconstruction surgery to be performed. This study has demonstrated that there are no requirements for additional resources from primary care.
The Souter-Strathclyde prosthesis was used in 52 revisions of total elbow replacements (TERs) between August 1986 and May 1997. Of these, 50, carried out in 45 patients, were prospectively followed for a mean of 53 months (14 to 139). The procedure produced reliable relief of pain, and the range of movement was preserved. There was a considerable incidence of adverse events associated with revision (30%), and 12 further procedures have been required. Nonetheless, a revision is the preferred salvage procedure for failed primary arthroplasty in the absence of sepsis.
We obtained intervertebral discs with cartilage endplates and underlying cancellous bone at operation from patients with degenerative disc disease and then used immunohistochemical techniques to localise the nerves and nerve endings in the specimens. We used antibodies for the ubiquitous neuronal protein gene product 9.5 (PGP 9.5). Immunoreactivity to neuropeptide Y was used to identify autonomic nerves and calcitonin gene-related peptide (CGRP) and substance P to identify sensory nerves. Blood vessels were identified by immunoreactivity with platelet-endothelial cell-adhesion molecule (CD31; PECAM). In a control group with no known history of chronic back pain, nerve fibres immunoreactive to PGP 9.5 and neuropeptide Y were most closely related to blood vessels, with occasional substance P and CGRP immunoreactivity. In patients with severe back pain and markedly reduced disc height, proliferation of blood vessels and accompanying nerve fibres was observed in the endplate region and underlying vertebral bodies. Many of these nerves were immunoreactive to substance P or CGRP, and in addition, substance P- and CGRP-immunoreactive nociceptors were seen unrelated to blood vessels. Quantification by image analysis showed a marked increase in CGRP-containing sensory nerve fibres compared with normal control subjects. We speculate that a chemotactic response to products of disc breakdown is responsible for the proliferation of vascularity and CGRP-containing sensory nerves found in the endplate region and vertebral body adjacent to degenerate discs. The neuropeptides substance P and CGRP have potent vasodilatory as well as pain-transmitting effects. The increase in sensory nerve endings suggests increase in blood flow, perhaps as an attempt to augment the nutrition of the degenerate disc. The increase in the density of sensory nerves, and the presence of endplate cartilage defects, strongly suggest that the endplates and vertebral bodies are sources of pain; this may explain the severe pain on movement experienced by some patients with degenerative disc disease.
