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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 156 - 156
1 Apr 2012
Bhattacharya D Cooke R Nagaria J
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Thoracic spinal cord herniation is a relatively uncommon syndrome of anterior hemi cord dysfunction. However it has been reported in literature with increasing frequency over the last decade. Since the initial description of this clinical entity by Weitzman et al. in 1974, more than 100 cases have been described.

Although clinical features may vary considerably, as a clinical syndrome it is now widely recognized, and remains a potentially treatable cause of thoracic cord dysfunction.

Anterior spinal or thoracic cord herniation remains an uncommon yet a potentially treatable cause of thoracic myelopathy. Patients usually present in their middle ages, and literature suggests that there is a female predominance. The presenting symptom is usually a Brown Sequard syndrome, although other symptoms suggestive of thoracic cord dysfunction may be present. Although the symptoms are insidious the condition may lead to progressive paraparesis. The herniation is usually through a dural defect, the cause of which open to speculation. Operative treatment is advised, as the outcomes are generally favourable.

As part of a continued focus on this clinical syndrome we describe below a series of 4 patients with thoracic spinal cord hernias that presented to our neurosurgical service over the past 3 years and our experience in the treatment of this condition. Apart from one patient, in whom there possibly was an iatrogenic factor, the rest were all purely idiopathic. All the patients underwent surgical treatment and their outcomes were generally favorable.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IV | Pages 4 - 4
1 Mar 2012
Chinwalla F Shafafy M Nagaria J Grevitt M
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Aim

To evaluate morbidity and outcome associated with lumbar spine decompression for central spinal stenosis in the elderly compared with younger age groups.

Patients & methods

Case notes review of patients with symptomatic and MRI proven central lumber canal stenosis, under the care of a single surgeon. The study population was 3 age groups: patients < 60 year of age (Group 1, n=21), patients between 60 and 79 years (Group 2, n=54), and > age of 80 years (Group 3, n=15).

Data with regard to intra- and post-operative complications and subjective outcome variables were collected. These included pain (VAS), walking distance, Oswestry Disability score (ODI) and patient satisfaction scores.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 478 - 478
1 Sep 2009
Shafafy M Nagaria J Grevitt M Webb J
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Background: Treatment of high-grade spondylolisthesis remains controversial. In-situ fusion does not address the sagital balance, reduction and fusion on the other hand is associated with unacceptably high rate of neurological complications.

Aim: To describe the results of a novel technique using Magerl External Fixateur for gradual reduction followed by circumferential fusion.

Methods: From 1988 to 2006, thirteen patients were treated with this technique at our institution. They all had high grade spondylolisthesis. Retrospective case note review and radiographic analysis were carried out. 10 point Visual Analogue Sore (VAS) for pain, Oswestry Disability Index (ODI), Low Back Outcome Score (LBOS), SF-36 Health Survey, and Patient Satisfaction Questionnaire were collected. Complete set of data was available for 9 patients, 7 Female and 2 Male. Mean age at operation was 16 years (range 12–22), and average length of follow-up was 11 years (range 5–19)

Results: Post operatively, Percentage of Slip was improved by an average of 70%(range 32–96%)(p=0.001), Slip Angle by 72%(p=0.0001) and sacral Inclination by 59%(p=0.0016). Radiological fusion was achieved in all but one. VAS for leg and back pain improved from 8.4 (range 8–9) and 8.2 (range 6–10) to 0.8(range 0–2) and 1.2 (range 0–2) respectively. These improvements were statistically significant (p< 0.001). ODI at the latest follow-up averaged 8% (range 0–16%) and LBOS 56.6 (range 44–70). The mean SF-36 for physical domains was 87.5 (range 80–93) and that for the psychological domains was 91.25 (range 81–100). All patients were fully satisfied. 3 cases had culture negative excessive discharge from one pin site. 2 patients developed transient parasthesia and one patient developed asymptomatic pseudoarthrosis.

Conclusion: Our technique albeit in a small cohort of patients, achieved significant correction of the commonly used and widely accepted radiological measurements without any neurological complications. The radiological improvement was also reflected in statistically significant improvement in validated outcome measures.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 480 - 480
1 Sep 2009
Thomas P Sattar T Nagaria J Bolger C
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INTRODUCTION: Atlanto-axial instability due to Rheumatoid arthritis has been treated by posterior C1/C2 wiring techniques supplemented with bone graft. Magerls technique of Transarticular fixation provides a three-point fixation by eliminating motion, promoting fusion, increased mechanical strength and treating instability. It allows fixation across the plane of movement and prevents basilar invagination.

The clinical results of transarticular fixation are satisfactory in terms of clinical outcome with few complications. However there are concerns that these patients develop subaxial kyphosis. It is important to highlight that none of these patients in our series had supplementary wiring techniques with TAS The purpose of this study is to analyse postoperative Xrays of patients who have undergone transarticular atlantoaxial fixation and look at the following parameters;

What percentage of patients develop subaxial kyphosis?

Are the ADI and PADI maintained postoperatively?

Is there a late failure rate of TAS despite the absence of supplementary wiring techniques?

MATERIALS & METHODS: 15 patients underwent pre and postoperative cervical spine X-rays in the AP and lateral projections. In addition flexion/extension views were also obtained pre and postoperatively.

We analysed the following parmeters:

Pre and Postoperative ADI and PADI.

C0/C1, C1/C2, C1/C7, C2/C7 angles

C2/C3 slip and C2/C3 osteoarthritis

Any breakage or pullout of screws.

Postoperative basilar invagination.

It is important to highlight that all these 15 patients had bony fusion at the C1/C2 joints and these findings have been analysed and published in the clinical counterpart of this study (Fusion rates 97% in 36/37 patients).

RESULTS: As highlighted, the clinical outcome of these patients has been published. We would like to present the radiological parameters of this subgroup of patients. The ADI improved in 13 patients with a preoperative median of 7 and postoperatively 3.5. The preoperative and postoperative PADI remained at 15. The C0/C1 angle changed from 12 to 17 postoperatively. The C2/C7 angle changed from 21 to 26 postoperatively. C1/C7 angle changed from 39 to 41. The spinal cord diameter remained at 15 pre and postoperatively.

There was only 1 patient with C2/C3 slip on flexion/extension views. 2 patients developed subaxial kyphosis with evidence of significant disc degeneration on preoperative imaging.

There are some interesting conclusions from these 15 xrays.

Only 2 out of 13 patients have developed a subaxial kyphosis.

The 2 patients that have developed subaxial kyphois had subaxial disc degeneration at the level of the kyphois

There was only 1 patient with a C2/C3 spondylolisthesis on flexion/extension.

The ADI and SAC were maintained at the craniocervical junction.

There is no late failure rate despite the absence of a modified gallie fusion


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 526 - 526
1 Aug 2008
Chinwalla F Shafafy M Nagaria J Grevitt MP
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Aim: To evaluate morbidity and outcome associated with lumbar spine decompression for central spinal stenosis in the elderly compared with younger age groups.

Patients & Methods: Case notes review of patients with symptomatic and MRI proven central lumber canal stenosis, under the care of a single surgeon. The study population was 3 age groups: patients < 60 year of age (Group 1, n=19), patients between 61 and 79 years(Group 2, n=54), and > age of 80 years (Group 3, n=15).

The number of levels decompressed & grade of surgeon were noted.

Outcome data: Length of operation & hospital stay, blood loss, and intra and post operative complications. Subjective variables: Pain (VAS), walking distance, Oswestry Disability score (ODI) and patient satisfaction scores.

Results: The duration of operation (p< 0.05), and intra-operative complication rate (p< 0.025) was dependent on the seniority of the surgeon.

There was a statistically significant improvement in VAS score for leg pain (p< 0.05) and back pain (p< 0.05) after surgery for each group. The average walking distance improved by factor 5 in group 1 and 2 and by factor 2.5 in group 3 (p< 0.05)

Conclusions: Surgery for neurogenic claudication in the octogenarian is associated with a higher complication rate. The outcomes in this patient group is however comparable to younger patients.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 526 - 526
1 Aug 2008
Shafafy M Nagaria J Judd S Grevitt MP
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Objective: To report a consecutive series of patients who underwent staged reduction and fusion with the Magerl External Fixator and 360° fusion for high grade slips and spondyloptosis.

Design: Prospective observational study.

Patients & methods: There were 11 patients, average age 17 years (range 9–25 years).

All these patients had equal or greater than Meyerding grade III slips.

Clinical presentation included severe back pain with disability and a severe cosmetic deformity (including flexed knees, proptotic abdomen and loin creases).

The indications for surgery were pain relief and neurological symptoms/signs, and to improve the sagittal alignment.

Surgery consisted of first stage Gill procedure, L5 root decompression, and insertion of Schanz pins into L4 pedicles and ilium, and application of the fixateur-externe. Second stage consisted of gradual correction of kyphosis and translation (average 1 week duration). Third stage entailed anterior interbody fusion, removal of fixator and instrumented fusion L5 to sacrum.

Outcome measures: Functional out comes (pain scores [VAS], activities of daily living) cosmesis, complications (including neurologic status) and radiographic parameters.

Results: Average follow-up was 3 years and 3 months. Postoperatively none of these patients developed a neurological deficit. Imaging confirmed solid fusion in all patients. In terms of reduction, 1 patient failed to reduce (fusion in-situ) and 1 patient developed subsequent L4 on L5 spondylolisthesis. There was no case of permanent neurologic deficit.

Nine (82%) patients reported improved pain scores on the VAS, improved quality of life and cosmetic appearance.

There was significant reduction of the translation (in most cases to grade II) and correction of the lumbosacral kyphosis. All patients went on to a solid arthrodesis and there was no late loss of correction.

Conclusions: Staged reduction and Fusion not only improves a severe cosmetic deformity but also restores sagittal balance. We recommend this technique as there is negligible risk of neurological complications, and avoids fusion involving two motion segments.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 448 - 448
1 Aug 2008
Nagaria J McEvoy L Bolger C
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Objective: To review the clinical outcome of 37 consecutive patients undergoing C1– C2 transarticular fixation for patients with Rheumatoid Arthritis.

Design: Prospective Observational Study.

Methods: There were 37 patients at 2 centres. Age range was 37– 82 years. The time since diagnosis to treatment was 2– 23 years. Clinical presentation included suboccipital pain in 26/ 37 patients and neck pain in 29/37 patients. 22 patients had presented with myelopathy ( Ranawat grade II or III A). The preoperative imaging included Plain X Rays, CT scans and MRI scans. All patients underwent C1/ C2 transarticular screws ( Stealth guided) except 4 patients in which an aberrant course of the vertebral artery was identified.

Outcome measures: Functional outcome, Complications, Postoperative Neurological Status, Neck Disability index, Myelopathy disability index.

Results: 1 patient had died at 12 month followup. Neck pain improved in 22( 75%) of patients by > 5 points on the VAS. Suboccipital pain had improved in all patients. 17 patients (80%) improved following operation on the Ranawat Grading, 2 patient were worse and 3 patients remained the same.

> 70% patients reported improvement in neck disability index and > 50% patients reported improvement in myelopathy disability index.

Conclusions: C1/ C2 Transarticular fixation with spinal navigation is a safe technique for treating atlantoaxial instability in patients with Rheumatoid Arthritis. This study demonstrates improvement in all domains including neck disability, myelopathy scores and functional outcome.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_III | Pages 341 - 341
1 Nov 2002
Kumar R Bolger CM Little CP Nagaria J Patel N
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Objective: Spontaneous spinal subdural haematoma is a rare cause of spinal cord compression usually confined to a few vertebral levels. When the haematoma extends over several spinal segments, surgical decompression is a major undertaking. A minimally invasive technique of decompression, using topical recombinant tissue plasminogen activator (rt-PA), is presented in two patients with extensive spinal intradural haematoma.

Clinical Presentation: Two patients, receiving long-term anticoagulation therapy, presented with acute-onset back pain progressing to paraparesis. MRI of the spine demonstrated spinal subdural haematomas extending over fifteen vertebral levels in one and twelve in the other patient.

Intervention: An angiography catheter was introduced into the subdural space through a limited laminectomy. Thrombolysis and evacuation of haematoma was then achieved by intermittent irrigation of the subdural space with recombinant tissue plasminogen activator (rt-PA), followed by saline lavage. Post-operative imaging demonstrated satisfactory decompression in both patients. There was significant improvement of neurological function in one patient.

Conclusion: Topical application of rt-PA for spinal sub-dural haematoma allows evacuation of the haematoma through a limited surgical exposure. Decompression of the subdural space by this minimally invasive technique may be advantageous over extensive surgery by minimizing surgical exposure, reducing postoperative pain and risk of neuronal injury. This technique may be useful in patients presenting with compression extending over several vertebral levels or poor surgical candidates.