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Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_14 | Pages 18 - 18
1 Nov 2021
Sedel L Bizot P Garcia-Cimbrelo E
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Fracture risks are the most common argument against the use of Ceramic on ceramic (CoC) hip implants. Question: is ceramic material at risk in case of severe local trauma?

Over a long period, we tried to identify patients with a CoC prosthesis (Ceraver Osteal°)who did sustain a trauma. This was conducted in three different institutions.

Eleven patients were found: 9 males and 2 females aged 17 to 70 years at time of index surgery. Accident occurred 6 months to 15 years after index: one car accident, five motorcycle accident, five significant trauma after a fall, including one ski board accident. Consequences of these trauma were: six fractures of the acetabulum with socket loosening in 4 that needed revision, two femoral shaft fracture, one orifed and one stem exchanged, one traumatic hip dislocation associated to loosening of the socket revised at 10 years, and one traumatic loosening of the socket. Ten had no consequence on ceramic integrity. One experienced a fracture of the patella from a dashboard trauma, a liner shipping was discovered during socket revision 2 years later. This is the only case of possible relation between trauma and ceramic fracture. In a more recent longitudinal study on 1856 CoC prosthesis performed from 2010 to 2021, 29 severe traumas were identified with no consequence on Ceramic material.

From this limited case study, it can be assumed that Pure Alumina Ceramic well designed and manufactured, will not break after a significant trauma.


The Bone & Joint Journal
Vol. 103-B, Issue 3 | Pages 492 - 499
1 Mar 2021
Garcia-Rey E Saldaña L Garcia-Cimbrelo E

Aims

Bone stock restoration of acetabular bone defects using impaction bone grafting (IBG) in total hip arthroplasty may facilitate future re-revision in the event of failure of the reconstruction. We hypothesized that the acetabular bone defect during re-revision surgery after IBG was smaller than during the previous revision surgery. The clinical and radiological results of re-revisions with repeated use of IBG were also analyzed.

Methods

In a series of 382 acetabular revisions using IBG and a cemented component, 45 hips (45 patients) that had failed due to aseptic loosening were re-revised between 1992 and 2016. Acetabular bone defects graded according to Paprosky during the first and the re-revision surgery were compared. Clinical and radiological findings were analyzed over time. Survival analysis was performed using a competing risk analysis.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 58 - 58
1 Feb 2020
Garcia-Rey E Garcia-Cimbrelo E
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Introduction

Biological repair of acetabular bone defects after impaction bone grafting (IBG) in total hip arthroplasty could facilitate future re-revisions in case of failure of the reconstruction again using the same technique. Few studies have analysed the outcome of these acetabular re-revisions.

Patients and Methods

We analysed 34 consecutive acetabular re-revisions that repeated IBG and a cemented cup in a cohort of 330 acetabular IBG revisions. Fresh-frozen femoral head allografts were morselized manually. All data were prospectively collected. Kaplan-Meier survivorship analysis was performed. The mean follow-up after re-revision was 7.2 years (2–17). Intraoperative bone defect had lessened after the first failed revision. At the first revision there were 14 hips with Paprosky 3A and 20 with Paprosky type 3B. At the re-revision there were 5 hips with Paproky 2B, 21 with Paprosky type 3A and 8 with type 3B. Lateral mesh was used in 19 hips.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 65 - 65
1 Feb 2020
Garcia-Rey E Garcia-Cimbrelo E
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Introduction

Pelvic tilt can vary over time due to aging and the possible appearance of sagittal spine disorders. Cup position in total hip arthroplasty (THA) can be influenced due to these changes. We assessed the evolution of pelvic tilt and cup position after THA and the possible appearance of complications for a minimum follow-up of ten years.

Materials and methods

343 patients received a cementless THA between 2006 and 2009. All were diagnosed with primary osteoarthritis and their mean age was 63.3 years (range, 56 to 80). 168 were women and 175 men. 250 had no significant lumbar pathology, 76 had significant lumbar pathology and 16 had lumbar fusion. Radiological analysis included sacro-femoral-pubic (SFP), acetabular abduction (AA) and anteversion cup (AV) angles. Measurements were done pre-operatively and at 6 weeks, and at five and ten years post-operatively. Three measurements were recorded and the mean obtained at all intervals. All radiographs were evaluated by the same author, who was not involved in the surgery.


The Bone & Joint Journal
Vol. 101-B, Issue 4 | Pages 378 - 385
1 Apr 2019
García-Rey E Carbonell-Escobar R Cordero-Ampuero J García-Cimbrelo E

Aims

We previously reported the long-term results of the cementless Duraloc-Profile total hip arthroplasty (THA) system in a 12- to 15-year follow-up study. In this paper, we provide an update on the clinical and radiological results of a previously reported cohort of patients at 23 to 26 years´ follow-up.

Patients and Methods

Of the 99 original patients (111 hips), 73 patients (82 hips) with a mean age of 56.8 years (21 to 70) were available for clinical and radiological study at a minimum follow-up of 23 years. There were 40 female patients (44 hips) and 33 male patients (38 hips).


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_4 | Pages 23 - 23
1 Apr 2019
Garcia-Rey E Garcia-Cimbrelo E Carbonell R
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Background

Aseptic loosening is rare with most cementless tapered stems in primary total hip arthroplasty (THA), however different factors can modify results. We ask if the shape and technique of three current different femoral components affects the clinical and radiological outcome after a minimum follow-up of ten years.

Methods

889 cementless tapered stems implanted from 1999 to 2007 were prospectively followed. Group 1 (273 hips) shared a conical shape and a porous-coated surface, group 2 (286 hips) a conical splined shape and group 3 (330 hips) a rectangular stem. Clinical outcome and anteroposterior and sagittal radiographic analysis were compared. Femoral type, stem position, femoral canal filling at three levels and the possible appearance of loosening and bone remodelling changes were assessed.


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_4 | Pages 24 - 24
1 Apr 2019
Garcia-Rey E Garcia-Cimbrelo E
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Introduction

Impaction bone grafting (IBG) is a reliable technique for acetabular revision surgery with large segmental defects. However, bone graft resorption and cup migration are some of the limitations of this tecnique. We assess frequency and outcome of these complications in a large acetabular IBG series.

Patients and Methods

We analysed 330 consecutive hips that received acetabular IBG and a cemented cup in revision surgery with large bone defects (Paprosky types 3A and 3B). Fresh-frozen femoral head allograft was morselized manually. The mean follow-up was 17 years (3–26). All data were prospectively collected. Kaplan-Meier survivorship analysis was performed. Changes in different paremeters regarding cup position were assessed pre- and postoperatively and at the follow- up controls. Only variations greater than 5º and 3 mm were considered.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_11 | Pages 34 - 34
1 Aug 2018
García-Rey E García-Cimbrelo E Cordero-Ampuero J
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We assessed the clinical and radiological outcome of a single uncemented total hip replacement (THR) after twenty years, analysing polyethylene wear and osteolysis.

82 hips implanted between 1992 and 1995 were prospectively evaluated. Mean follow-up was 20.6 years (18–23). A hemispherical porous-coated cup matched to a proximally hydroxyapatite-coated anatomic stem. A 28mm PE liner, sterilised by gamma irradiation in air, was used in all hips. Radiological position, eventual loosening and osteolysis were recorded over time. Penetration of the head into the liner was measured by the Roentgen Monographic Analysis (ROMAN) Tool at 6 weeks, 6 months, one year and yearly thereafter.

Six cups were revised due to wear and four cups because of late dislocation. All stems showed osseointegration and all cups appeared radiographically well-fixed. Six unrevised hips showed osteolysis on the acetabular side and two hips on the proximal femur. Creep at one year was 0.30±0.23 mm. Mean total femoral head penetration was 1.23mm at ten years, 1.52mm at 15 years and 1.92mm at 23 years. Overall mean wear was 0.12±0.1 mm/year and 0.09±0.06 mm/year after the creep period. Mean wear was 0.08±0.06 mm/year in hips without osteolysis and 0.14±0.03 mm/year in hips revised or hips with osteolysis (p<0.001).

Although continued durable fixation can be observed with porous-coated cups and proximally hydroxyapatite-coated anatomic stems, true wear continues to increase at a constant level over time. PE wear remains as the main reason for osteolysis and revision surgery in uncemented THR after twenty years.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_5 | Pages 58 - 58
1 Apr 2018
Garcia-Rey E Garcia-Cimbrelo E Sedel L
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Introduction

Acetabular fractures management is controversial since, despite a good anatomical reduction, clinical outcome is not satisfactory very often and the probability of a total hip arthroplasty (THA) is high. Surgical treatment include long operating times, large approach, blood loss, neural and muscle damage, and a high risk of failure and secondary osteoarthritis related to bone necrosis, cartilage damage, and bone loss.

We hypothesized that the acetabular fracture management affected the clinical and radiological outcome of THA after posttraumatic arthritis.

Materials and Methods

We compared 49 patients (49 hips) initially treated conservatively followed some months later by THA in conjunction with acetabular reconstruction (group 1); and 29 patients (29 hips) who had undergone THA after a failed osteosynthesis (group 2). There were more associated fractures according to Letournel in group 2. The mean age was 59.3±15.8 years for group 1 and 52.9±15.2 years for group 2. The mean delay between fracture and THA was 75.4±5 months for group 1 and 59.4±5 for group 2. The mean follow-up was 11.7 in group 1 and 10.2 in group 2. Preoperative bone defect was similar. We used bone autograft in 13 hips (26.5%) in group 1 and four (13.6%) in group 2. We used acetabular reconstruction plates in 2 hips with a pelvic discontinuity in group 1. Complications, clinical outcome according to Harris Hip Score, and radiological reconstruction were compared. Two-way ANOVA with repeated measures were used for comparison.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 49 - 49
1 Jan 2018
Garcia-Cimbrelo E Garcia-Rey E Sedel L
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Different pathologies, deformities, bone defects, previous surgeries and polyethylene wear limit the survival of total hip arthroplasty (THA) in young patients. We compare preoperative status and outcome in 171 young and very young patients (207 hips) who underwent a ceramic-on-ceramic THA. Sixty-three (77 hips) were less than 30 years old (group 1) and 108 (130) were between 30 and 40 years old. Mean follow-up was 11.3 years. Two-way ANOVA with repeated measures were used to analyse clinical and radiological changes.

Juvenile rheumatoid arthritis (JRA) was the most frequent diagnosis in group 1 and avascular necrosis in group 2. Charnley class type C, low activivity, previous surgery and osteoporotic bone were more frequent in group 1 patients. There were 2 cup revisions for aseptic loosening in group 1 and 4 in group 2. Survivorship analysis at 15 years was 96.7% (95% IC 92.2 a 100) for group 1 and 96.1% (95% IC 92.2 to 100) for group 2 (p=0.749). Despite the worse preoperative status in group 1 patients, clinical outcome was similar in both groups. Severe dysplasia had the worst clinical result and avascular necrosis the best. Patients with Charnley class C and JRA showed the most improvement. Radiographic reconstruction of the abduction angle was worse in group 1 (p=0.02). No osteolysis or complications derived from ceramic use were found.

We conclude that despite the worse preoperative status in group 1 patients, clinical and radiographic results were good in both groups of patients who received a ceramic-on-ceramic THA.


The Bone & Joint Journal
Vol. 99-B, Issue 6 | Pages 749 - 758
1 Jun 2017
García-Rey E Cruz-Pardos A García-Cimbrelo E

Aims

To determine the effect of a change in design of a cementless ceramic acetabular component in fixation and clinical outcome after total hip arthroplasty

Patients and Methods

We compared 342 hips (302 patients) operated between 1999 and 2005 with a relatively smooth hydroxyapatite coated acetabular component (group 1), and 337 hips (310 patients) operated between 2006 and 2011 using a similar acetabular component with a macrotexture on the entire outer surface of the component (group 2). The mean age of the patients was 53.5 (14 to 70) in group 1 and 53.0 (15 to 70) in group 2. The mean follow-up was 12.7 years (10 to 17) for group 1 and 7.2 years (4 to 10) for group 2.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_9 | Pages 77 - 77
1 May 2017
García-Rey E Gómez-Barrena E García-Cimbrelo E
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Background

Although the tribological characteristics are excellent, cup fixation has been one of the limitations in alumina-on-alumina total hip replacement (THR), so different types of materials and surfaces have been developing. We analysed the clinical and radiological outcome of two different uncemented cups for the same alumina-on-alumina THR.

Methods

679 hips were prospectively followed for at least 5 years. 342 had a hydroxyapatite (HA)-coated relatively smoothed tri-radius cup, implanted between 1999 and 2005 (group 1), and, 337 had a HA-coated macotextured tri-radius implanted between 2006 and 2009 (group 2). Dysplastic hips were more frequently observed in group 2. We compared screw use in both groups as primary fixation, the clinical results, and the radiological appearance of cup loosening.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_8 | Pages 78 - 78
1 Apr 2017
García-Rey E García-Cimbrelo E Gómez-Barrena E
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Background and aim

Recent proposals have been introduced to modify stem design and/or femoral fixation in total hip replacement (THR). New designs need to consider previous design features and their results. The aim of this study has been to evaluate the clinical and radiological results of six different designs of tapered uncemented stems implanted in our Institution.

Methods

1918 uncemented hips were prospectively assessed from 1999 to 2011 (minimum follow-up of five years for the unrevised hips). All hips had a 28 or 32 mm femoral head and metal-on-polyethylene or alumina-on-alumina bearing surface. Six uncemented femoral designs that shared a femoral tapered stem incorporating a coating surface were included in the study. The different design features included the type of coating, metaphyseal filling, and sectional shape.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 56 - 56
1 Jan 2017
García-Rey E Gómez-Barrena E García-Cimbrelo E
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Total hip replacement (THR) in young patients has been associated to higher revision rates than in older population. Different conditions may lead to end-stage arthritis of the hip in these patients. We compared the clinical and radiological outcome of two different groups of young and very young patients who underwent a ceramic-on-ceramic THR.

120 hips were prospectively followed for a mean of 10.4 years (range, 5 to 17). 38 patients (46 hips) were less than 30 years old (group 1), and, 68 (74 hips) were between 31 and 40 years old (group 2). Weight (p<0.001) and physical activity level were greater in group 2 (p<0.001). Preoperative function (p=0.03) and range of mobility (p=0.03) were worse in group 1. Primary osteoarthritis was not found in any case. Rheumatoid juvenile arthritis was the most frequent diagnosis in group 1 and avascular necrosis of the femoral head in group 2. A femoral funnel-shaped type 1 according to Dorr was more frequent in group 2 (p=0.04). The same ceramic-on-ceramic uncemented THR was used in all cases. Screws for cup fixation were only used when strictly needed. We analysed the clinical results according to the Merle-D´Aubignè and Postel scale, the postoperative radiological reconstruction of the hip and the radiological appearance of cup loosening. Kaplan-Meier survivorship analysis was used to estimate the cumulative probability of not having a revision surgery.

Screw use required to obtain a secured interference fit of the acetabular component was found more frequently in group 1 (p=0.01). Postoperative pain (p=0.002) and function (p=0.002) were better in group 1. Mean acetabular abduction angle of the cup was greater in group 1 (p=0.03) and reconstruction to the hip rotation center according to Ranawat (p=0.01) was better in group 2. Placement of the acetabular component inside the Lewinnek´s zone and stem position were similar in both groups. No hips were revised due to complications related to ceramic or to stem loosening. Three cups were revised for aseptic loosening in group 1 and four in group 2. The survival rate for cup aseptic loosening at 15 years was 92.3% (95% CI: 83.7 to 100) for group 1 and 93.1% (95% CI: 85.3 to 99.9) for group 2 (Log rank, p=0.88).

Ceramic-on-ceramic uncemented THR is an excellent option for young and very young patients. Despite worse preoperative conditions in patients under the age of 30 years, a similar clinical outcome was found in this series.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_7 | Pages 146 - 146
1 May 2016
Garcia-Cimbrelo E Garcia-Rey E
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Introduction

Alumina-on-alumina in total hip replacement has been used for avoiding osteolysis and loosening. Published series report no ceramic wear and low rates for fractures and noises, but report poor results because of acetabular fixation failure. From 1999 to 2005, we used the “first generation” of a cementless cup, tri-radius relatively-smoothed HA coated (group 1), and from 2006 we have used a “second-generation” of this same cementless cup design with a macrotextured surface (group 2). We compare the perioperative conditions of two groups of patients using these two different cups and the clinical and radiological results.

Material and Methods

We analysed 679 (612 patients) consecutive and non-selected primary cementless alumina-on-alumina prostheses. There were 342 hips in group 1 and 337 in group 2. The stem used for all patients in this series was the same and fitted with an Al2O3 liner and femoral head. The use of screws were according to the intraoperative stability of the cup (pull-out test). Patients’ mean age was 48.7+13.6 years and the average follow-up until revision or the last evaluation was 11.7 years for group 1 and 5.4 years for group 2.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_7 | Pages 147 - 147
1 May 2016
Garcia-Rey E Garcia-Cimbrelo E
Full Access

Background and aim

Recent proposals have been introduced to modify stem design and/or femoral fixation in total hip replacement (THR). New designs need to consider previous design features and their results. The aim of this study has been to evaluate the clinical and radiological results of six different designs of tapered uncemented stems implanted in our Institution.

Methods

1918 uncemented hips were prospectively assessed from 1999 to 2011 (minimum follow-up of five years for the unrevised hips). All hips had a 28 or 32 mm femoral head and metal-on-polyethylene or alumina-on-alumina bearing surface. Six uncemented femoral designs that shared a femoral tapered stem incorporating a coating surface were included in the study. The different design features included the type of coating, metaphyseal filling, and sectional shape.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_7 | Pages 145 - 145
1 May 2016
Garcia-Cimbrelo E Garcia-Rey E
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Although cemented fixation provides excellent results in primary total hip replacement (THR), particularly in patients older than 75 years, uncemented implants are most commonly used nowadays. We compare the rate of complications, clinical and radiological results of three different designs over 75-years-old patients.

Materials and Methods

433 hips implanted in patients over 75 years old were identified from our Local Joint Registry. Group A consisted of 139 tapered cemented hips, group B of 140 tapered grit-blasted uncemented hips and group C of 154 tapered porous-coated uncemented hips. A 28 mm femoral head size on polyethylene was used in all cases. The mean age was greater in group A and the physical activity level according to Devane was lower in this group (p<0.001 for both variables). Primary osteoarthritis was the most frequent diagnoses in all groups. The radiological acetabular shape was similar according to Dorr, however, an osteopenic-cylindrical femur was most frequently observed in group A (p<0.001). The pre- and post-operative clinical results were evaluated according to the Merle-D'Aubigne and Postel scale. Radiological cup position was assessed, including hip rotation centre distance according to Ranawat and cup anteversion according to Widmer. We also evaluated the lever arm and height of the greater trochanter distances and the stem position. Kaplan-Meier analysis was done for revision for any cause and loosening.

Results

The hip rotation centre distance was greater and the height of the greater trochanter was lower in group B (p=0.003, p<0.001, respectively). The lever arm distance was lower in group C (p<0.001). A varus stem position was more frequently observed in group B (p<0.001). There were no intra- or post-operative fractures in group A, although there were five intra-operative fractures in the other groups plus two post-operative fractures in group B and four in group C. The rate of dislocation was similar among groups and was the most frequent cause for revision surgery (8 hips for the whole series). The mean post-operative clinical score improved in all groups. The overall survival rate for revision for any cause at 120 months was 88.4% (95% CI 78.8–98), being 97.8% (95% CI 95.2–100) for group A, 81.8% (95% CI 64.8–98.8) for group B and 95.3% (95% CI 91.1–99.6) for group C (log Rank: 0.416). Five hips were revised for loosening. The overall survival rate for loosening at 120 months was 91.9% (95% CI 81.7–100), being 99.2%(95% CI 97.6–100) for group A, 85.5 (95% CI 69.9 −100) for group B and 100% for group C (Log Rank 0.093).


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_7 | Pages 148 - 148
1 May 2016
Garcia-Rey E Garcia-Cimbrelo E
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Introduction

The use of screws is frequent for additional fixation, however, since some disadvantages have been reported a cup press-fit is desirable, although this can not always be obtained. Cup primary intraoperative fixation in uncemented total hip replacement (THR) depends on sex, acetabular shape, and surgical technique. We analyzed different factors related to primary bone fixation of five different designs in patients only diagnosed with osteoarthritis, excluding severe congenital hip disease and inflammatory arthritis, and their clinical and radiological outcome.

Materials y Methods

791 hips operated in our Institution between 2002 and 2012 were included for the analysis. All cases were operated with the same press-fit technique, and screws were used according to the pull-out test. Two screws were used if there was any movement after the mentioned manoeuvres. Acetabular and femoral radiological shapes were classified according to Dorr et al. We analyzed radiological postoperative cup position for acetabular abduction angle, the horizontal distance and the vertical distance. Cup anteversion was evaluated according to Widmer and the hip rotation centre according to Ranawat.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 151 - 151
1 Jan 2016
Garcia-Rey E Garcia-Cimbrelo E
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Introduction

Uncemented press-fit cups provide bone fixation in primary total hip replacement (THR). However, sometimes screws are needed to achieve primary stability of the socket. We analyzed biomechanical factors related to press-fit in seven cup designs and assessed whether screw use provides similar loosening rates to those of the press-fit technique.

Materials y Methods

From a series of 1,350 primary uncemented THRs using seven different press-fit cup designs (a dome loading hemispheric cup and bi- or tri- radius cups), we only analyzed the 889 diagnosed of primary osteoarthritis. All cases were operated by the same surgical team. The use of screws was decided intraoperatively based on cup stability according to the pull-out test. There were 399 female and 490 male patients with a mean age of 65 years old. The mean follow-up was 8.6 years (5–13 years). The reconstruction of the hip rotation center was evaluated according to Ranawat.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_1 | Pages 150 - 150
1 Jan 2016
Garcia-Rey E Garcia-Cimbrelo E
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Background

Cup migration and bone graft resorption are some of the limitations after acetabular impaction bone grafting (IBG) technique in revision hip surgery when used for large segmental defects. We asked whether the use of a metallic mesh may decrease the appearance of this complication. We compared the appearance of loosening in patients with a bone defect 3A or 3B according to Paprosky.

Materials and Methods

We assessed 204 hips operated with IBG and a cemented cup according to Slooff et al between 1997 and 2004. There were 100 hips with a preoperative bone defect of 3A and 104 with a 3B. We used 142 medial and/or rim metallic meshes for uncontained defects. The mean follow-up for unrevised cups was 10.4 years. We detemined postoperative radiological cup position and acetabular reconstruction of the hip center according to Ranawat in both groups. We assessed the appearance of radiological loosening and resorption of the graft.