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Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_10 | Pages 71 - 71
1 Oct 2022
MANAGEMENT OF HIP AND KNEE PROSTHESIS JOINT INFECTION (PJI) DUE TO S. AUREUS BY THE “DEBRIDEMENT ANTIBIOTICS AND IMPLANT RETENTION” (DAIR) PROCEDURE IN FRENCH REFERENCE CENTRES (CRIOACS) IN 2019: A RETROSPECTIVE COHORT STUDY
Ferry T Arvieux C Stendel E Nich C Delobel P Zeller V Sotto A Dauchy F RONDE-OUSTAU C Tizon A
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Aim

To describe the management of PJI due to S. aureus in CRIOAcs in 2019 and to particularly focus on the evaluation of the efficacy of DAIR regarding control of infection and risk factors for failure up to 12 months.

Method

Thirteen CRIOAcs were selected to participate to the study. Data concerning the management of all the PJI in the year 2019 were retrospectively collected and registered in eCRFs. Inclusion criteria were: ≥ 18 years old patients with S. aureus ± other bacteria (in per surgical procedure sample); knee or hip PJI and with clinical signs of infection. Patients treated with bacteriophages were excluded. All eligible patients were notified by an information letter. Patients treated by the DAIR procedure were selected, and rate of control of infection (no inflammatory local signs or no new surgical procedure or no S. aureus in case of puncture) was analyzed using Kaplan Meier method and risk factors for failure at 12 months were assessed using Cox regression model.

Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_22 | Pages 13 - 13
1 Dec 2017
AGREEMENT BETWEEN PRE-OPERATIVE AND INTRA-OPERATIVE BACTERIOLOGICAL SAMPLES IN 85 CHRONIC PERIPROSTHETIC HIP AND KNEE INFECTIONS
Jenny J Matter-Parrat V Ronde-Oustau C
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Aim

Whether pre-operative microbiological sampling contributes to the management of chronic peri-prosthetic infection remains controversial. We assessed agreement between the results of pre-operative and intra-operative samples in patients undergoing single-stage prosthesis exchange to treat chronic peri-prosthetic infection. The tested hypothesis was that agreement between pre-operative and intra-operative samples exceeds 75% in patients undergoing single-stage exchange of a hip or knee prosthesis to treat chronic peri-prosthetic infection.

Method

This single-centre retrospective study included 85 single-stage prosthesis exchange procedures in 82 patients with chronic peri-prosthetic infection at the hip or knee. Agreement between pre-operative and intra-operative sample results was evaluated. Changes to the initial antibiotic regimen made based on the intra-operative sample results were recorded. Associations between sample agreement and infection-free survival were assessed.