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Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 241 - 241
1 May 2009
Wotherspoon SDM Giffin JR Fowler PJ Litchfield RB Neligan M Willits KR
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The purpose of our study is to determine if hamstring autograft size can be predicted preoperatively. We will define a relationship between patient body size (BMI, height, and weight) and harvested graft size, as well as define a relationship between the preoperative MRI cross-sectional area (CSA) of hamstring tendons and harvested graft size. This information will be useful as a tool for preoperative planning in graft choice selection.

The pre-operative MRIs of one hundred and four patients (62M, 42F) who underwent ACL reconstruction using hamstring autografts were analyzed. Cross-sectional area (CSA) of the ST and G was measured on a single axial MRI image at the level of the knee joint. Combined CSA of both tendons was then compared to the diameter of the four-strand hamstring autograft measured intra-operatively. Patient BMI, height and weight was also compared to intraoperative hamstring autograft size. Linear regression analysis was then performed to define the relationship and predictive value of body size on graft diameter.

Mean graft size was 7.4mm (range 6 – 9). Average graft size for men and women, 7.6mm and 7.1mm, respectively. Predicting graft size from BMI: r= 0.29, R2= 0.08. Predicting graft size from height: r= 0.52, R2= 0.27. Predicting graft size from weight: r= 0.5, R2= 0.25. On preoperative MRI, the mean CSA of ST and G was 9.8mm2 (range 5.4 – 17.7) and 4.5mm2 (range 1.8 – 9.4) respectively, with a total CSA of 14.3mm2 (range 8.4 – 25). If the total CSA was greater than 12mm2, a graft of 7.0mm or greater could be predicted 93% of the time, with sensitivity and specificity, 78% and 76%, respectively, and a LR of 3.25.

Body size is a poor predictor of hamstring graft size in ACL reconstruction, and therefore a large patient does not always provide a large graft from harvested hamstring tendons. MRI assessment of hamstring tendons can be a useful tool for preoperative planning, providing a strong predictive value of graft size from a simple calculation.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_II | Pages 130 - 130
1 Feb 2004
Cleary M Neligan M Dudeney M Quinlan W
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Nosocomial infection with methicillin-resistant Staphylococcus aureus (MRSA) is on the increase and is expensive to treat. MRSA surgical wound infection may have disastrous consequences, particularly in an orthopaedic setting. We studied the rate of MRSA colonization in an important subgroup of orthopaedic patients. 50 nursing home residents were retrospectively reviewed with regard to their MRSA status on admission to an orthopaedic ward with fractured neck of femur. As is policy in our institution, all patients from nursing homes or other institutions are screened for MRSA on admission.

Of the 50 nursing home patients requiring a hemi-arthroplasty, 16%(8) were MRSA positive. 2%(1/50) acquired MRSA infection while I hospital, while the remaining 14%(7/50) were carriers on admission. 4%(2/50) developed sepsis postoperatively, followed by multiorgan failure and death. 4% had their MRSA cleared prior to discharge, while 8% remained positive on discharge. All patients undergoing hemiarthroplasty received cefuroxime, unless allergic, as prophylaxis at induction. These findings of considerable MRSA carriage in nursing home patients is particularly relevant today, as the number of patients in nursing homes continues to grow as the population ages. The patient population in nursing homes is susceptible to infection because of the physiological changes that occur with ageing, the underlying chronic diseases of the patients and the institutional environment within which residents socialize and live.

Nursing home residents presenting to orthopaedic units for surgery are a unique group in repairing careful consideration.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_I | Pages - 8
1 Mar 2002
Morris S McCarthy T Neligan M Timlin M Gargan P Murray P O’Byrne J Quinlan W
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Introduction: Since the introduction of joint arthroplasty major advances including the introduction of laminar airflow, have been made in reducing infection to current rates of 1 to 2%. Nonetheless infection remains a devastating complication, with major implications in terms of patient suffering, duration of hospital stay and financial burden. We undertook a study to examine the incidence of bacterial wound contamination occurring in the intra-operative period.

Materials and Methods: All patients admitted to our unit for elective hip and knee arthroplasty were entered into the study. On arrival in theatre a skin swab was taken. The patient was then prepared and draped in the anaesthetic room before final draping by the surgical team in the operating theatre. All procedures were performed in theatres equipped with laminar airflow, and all surgical personnel wore isolator suits. During the course of the procedure swabs were taken from the anterior aspect of the femur at 30-minute intervals. In addition the skin and inside blades and the suction tip were harvested at the end of the procedure. All samples were then sent for culture. Patient data including age, comorbid conditions and history of previous surgery were noted on a standardised pro forma. In addition, operative data including duration of the procedure, operating surgeon and type of drape and skin preparation used were noted.

Results: 65 patients have been examined to date. An incidence of contamination of 14% has been noted (9 patients) with the skin blade and suction tip being the most common source of contaminating organisms. Staphylococcus epidermis was cultured in 5 cases, with Gram negative organisms being cultured in the remaining samples. In all 9 cases only small numbers of organisms were identified. None of the patients with positive cultures developed clinical signs of deep or superficial wound sepsis, and all had an uncomplicated postoperative course.

Conclusions: While low levels of contamination are unavoidable in theatre, it is important that strict discipline be maintained in order to minimise this risk. In particular, careful attention to patient skin preparation, the use of prophylactic antibiotics and minimising use of the suction tubing help decrease contamination rates.