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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_12 | Pages 60 - 60
1 Oct 2019
Dennis DA Elkins J Kleeman-Forsthuber LT Miner T Yang CC Jennings JM
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Introduction

Cutibacterium acnes (C. acnes) is now recognized as a clinical entity in periprosthetic joint infections (PJI) of the shoulder and spine. However, the colonization rate of C. acnes in the adult hip is currently unknown. Therefore, the purpose of this study was to investigate the rate of C. acnes colonization from the skin of healthy subjects from various anatomic locations corresponding to direct anterior and lateral/posterolateral surgical approaches.

Methods

90 patients scheduled for hip or knee surgery were recruited for cultured biopsies. Four 3-mm dermal punch biopsies were collected after administration of anesthesia, but prior to delivery of perioperative antibiotics. Pre-biopsy skin prep consisted of a standardized pre-operative 2% chlorhexidine skin cleanse and an additional 70% isopropyl alcohol mechanical skin scrub immediately prior to biopsy collection. Two culture samples 10-cm apart were collected from a location approximating a standard direct anterior skin incision, and two samples 10-cm apart were collected from a location approximating a lateral skin incision (suitable for a posterior, direct-lateral or anterolateral surgical approach). Samples were cultured for two weeks.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 55 - 55
1 Oct 2018
Jennings JM Loyd BJ Miner T Yang CC Stevens-Lapsley J Dennis DA
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Introduction

Closed suction intraarticular drain (CSD) use after total knee arthroplasty (TKA) has been studied with regards to wound healing and range of motion, however, no data exist on how CSD use impacts knee joint effusion and quadriceps strength. The primary purpose of this study was to determine whether CSD use influences recovery of quadriceps strength. Secondary outcomes examined effects of CSD on intraarticular effusion, lower limb swelling, knee range of motion (ROM), pain and wound healing complications.

Methods

Twenty-nine patients undergoing same-day bilateral TKA were enrolled in a prospective, randomized blinded study. Subjects were randomized to receive a CSD on one lower extremity while the contralateral limb had the use of a subcutaneous drain (SCDRN) without the use of suction. Isometric quadriceps strength was collected as the primary outcome. Secondary outcomes consisted of quadriceps muscle activation, intraarticular effusion measured via ultrasound, lower extremity swelling measured with bioelectrical impendence, lower extremity girth, ROM, and pain. Outcomes were assessed preoperatively and postoperatively at day 2, 2 and 6 weeks and 3 months. Differences in limbs were determined using paired t-tests or Wilcoxon signed rank tests.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_7 | Pages 135 - 135
1 May 2016
Foran J Dennis D Bade M Kim R Miner T Dayton M Struessel T Lapsley J
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INTRODUCTION

Early postoperative strength loss is pronounced following total knee arthroplasty (TKA) and is largely the result of reduced muscular activation. High-intensity progressive rehabilitation may limit postoperative weakness and improve long-term outcomes, but no randomized controlled trials have examined its use after TKA. The purpose of this trial was to examine the efficacy of a high-intensity progressive rehabilitation protocol (HI) compared to a lower intensity (LI) rehabilitation protocol after TKA.

METHODS

One hundred and sixty-two subjects (aged 63±7 years, 89 females) were randomized to either the HI group or LI groups after TKA. The HI intervention consisted of an early initiation of intensive rehabilitation using progressive resistance exercise. The LI intervention was based on a synthesis of previously published standard TKA rehabilitation programs. Both groups were treated 2–3 times per week for 12 weeks. Outcomes included the stair climbing test, timed-up-and-go test, five-times sit-to-stand test, 6-minute walk test, isometric quadriceps and hamstring strength, quadriceps activation, surgical knee range of motion, and WOMAC. Secondary analysis evaluated whether outcomes differed depending on post-operative quadriceps activation. Outcomes were assessed preoperatively and at 1, 2, 3, 6, and 12 months postoperatively.