header advert
Results 1 - 2 of 2
Results per page:
Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_16 | Pages 11 - 11
17 Nov 2023
Wahdan Q Solanke F Komperla S Edmonds C Amos L Yap RY Neal A Mallinder N Tomlinson JE Jayasuriya R
Full Access

Abstract

INTRODUCTION

In the NHS the structure of a “regular healthcare team” is no longer the case. The NHS is facing a workforce crisis where cross-covering of ward-based health professionals is at an all-time high, this includes nurses, doctors, therapists, pharmacists and clerks. Comprehensive post-operative care documentation is essential to maintain patient safety, reduce information clarification requests, delays in rehabilitation, treatment, and investigations. The value of complete surgical registry data is emerging, and in the UK this has recently become mandated, but the completeness of post-operative care documentation is not held to the same importance, and at present there is no published standard. This project summarises a 4-stage approach, including 6 audit cycles, >400 reviewed operation notes, over a 5 year period.

OBJECTIVE

To deliver a sustainable change in post operative care documentation practices through quality improvement frameworks.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_2 | Pages 90 - 90
1 Mar 2021
Mahatma M Jayasuriya R Gossiel F Gallagher O Hughes D Buckley S Gordon A Hamer A Tomouk M Wilkinson JM
Full Access

Abstract

Objective

In this phase 2 clinical trial (EudraCT 2011-000541-20) we examined the effect of denosumab versus placebo on osteolytic lesion activity in patients undergoing revision surgery after THA.

Methods

Men and women ≥ 30 years old scheduled for revision surgery for symptomatic, radiologically-confirmed osteolysis were randomised (1:1) to receive either denosumab 60mg or placebo subcutaneously eight weeks prior to operation. At surgery, biopsies from the osteolytic membrane-bone interface were taken for histomorphometric analysis of osteoclast number, the primary outcome measure. Secondary outcome measures included other static histomorphometric indices and systemic bone turnover markers. Adverse events and patient-reported clinical outcome scores were recorded as safety endpoints.