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Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_12 | Pages 41 - 41
1 Mar 2013
Zaghloul A Griffiths E Lawrence C Nicolai P
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To evaluate prospectively the mid-term results of the Zimmer Unicondylar Knee arthoplasty (UKA).

Between 2005 and 2012, 187 unicompartmental knee arthroplasties (UKA) were performed by a single surgeon using a fixed-bearing prosthesis (Zimmer). 37 cases were excluded as either were lost to follow-up or had less than six months follow-up. The study included 150 UKAs. Deformity, if present, was correctable. Patellofemoral joint (PFJ) disease was not considered as an absolute contraindication. The average patient age at the time of surgery was 66 years (range 42–88 years); 78 of which were male. Mean follow-up time was 3.6 years (range 7–81 months). Mean Body Mass Index (BMI) was 29 (range 21–41). Clinical and conventional radiological evaluations were carried out at six months, one, two and five years postoperatively.

147 cases were medial compartment replacement and three were lateral. 86 patients had grade III OA and 64 had grade IV (Kellgren and Lawrence). 113 patients had an element of PFJ disease. The mean Knee Society knee and function scores had an improvement from 55 and 54 points pre-operatively to 95 and 94 points respectively at time of most recent evaluation. The average flexion improved from 116 degrees pre-operatively to 127 degrees. Two cases were revised, one due to progression of osteoarthritis in the lateral compartment of the knee and the other was due to arthrofibrosis.

The Zimmer unicompartmental knee arthroplasty provided excellent pain relief and restoration of function in carefully selected patients. However, long-term studies are necessary to investigate the survival rate for this prothesis.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 113 - 113
1 Apr 2012
Thompson M Payton O Griffiths E Halsey T Rai A
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To audit the routine measurement of Vitamin B12 levels prior to cervical decompressive surgery

Retrospective analysis of medical records and pathology results of patients who underwent decompressive cervical surgery for myelopathy over a 6 month period

26 patients were identified from theatre records.

21 out of 26 patients did not have vitamin B12 levels checked prior to their decompressive surgery

The reports in the literature of co-existent B12 deficient myelopathy and mechanical compression are a cause for concern. Although the incidence of this is unknown and unlikely to be common, good clinical practice would suggest that we should be routinely monitoring B12 levels in myelopathic patients.

We have introduced new standards for routinely checking B12 levels pre-operatively and intend to re-audit the effectiveness of these in six months time.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 114 - 114
1 Apr 2012
Griffiths E Halsey T Berko B Grover H Blake J Rai A
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To establish the current practice of spinal cord monitoring in units carrying out scoliosis surgery in the UK.

To illustrate the benefit of routinely monitoring motor evoked potentials (MEPs).

Questionaire: Nationwide survey of spinal monitoring modalities used by spinal units carrying out deformity surgery.

10 out of 27 units routinely measure motor evoked potentials (MEPs), the remainder use only sensory potentials (SEPs). There is significant variability in use of monitoring around the UK and we have compared this to the practice elsewhere in the world.

We report the case of a thirteen year old girl who underwent posterior instrumentation for correction of an idiopathic scoliosis. Intra-operatively there was a significant reduction in the amplitude of the MEPs without any corresponding change in the SEPs. These changes reversed when the correction was released. The surgery was abandoned and was carried out as a staged procedure, initially anteriorly then posteriorly. There was no loss of motor potentials during either operation and no post operative neurological abnormalities.

We propose that the changes noted initially were due to transient ischaemia of the cord which would not have been detected without MEPs and may have led to long term sequelae. This highlights the safety benefit of routinely using MEPs in scoliosis surgery.

Nationally there is wide variation in the monitoring of spinal cord function during scoliosis surgery. We feel that monitoring of motor potentials is a vital component in ensuring scoliosis surgery is as safe as possible.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 25 - 25
1 Jan 2011
Kampa R Hacker A Griffiths E Rosson J
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We assessed polyethylene wear and osteolysis in 15 patients (30 hips) undergoing staged bilateral total hip arthroplasty, who had a cemented hip arthroplasty on one side and a hybrid arthroplasty on the other. All factors apart from mode of acetabular component fixation were matched. Wear was measured radiographically using Livermore’s technique.

The mean clinical and radiological follow-up was 11.2 years for the cemented arthroplasties and 10.7 years for the hybrid arthroplasties. Mean annual linear wear rate for the cemented cups was 0.09mm/year, and 0.14mm/year for the uncemented cups. This difference was statistically significant (p=0.03), confirming previous reports that polyethylene wear in uncemented cups is greater than in cemented cups. Polyethylene wear in the uncemented cup exceeded wear in the cemented cup by more than > 0.1mm/year in 5 patients, 4 of whom had a BMI of greater than 30.

No periacetabular osteolysis was noted. Femoral osteolysis was present in 5 hybrid arthroplasties and 2 cemented arthroplasties. Zone 7 femoral osteolysis occurred in 3 patients on the side of the hybrid arthroplasty, multifocal femoral osteolysis not involving zone 7 was seen in 2 patients in both hips.


The Journal of Bone & Joint Surgery British Volume
Vol. 71-B, Issue 2 | Pages 275 - 282
1 Mar 1989
Ostl O Fraser R Griffiths E

We compared retrospectively consecutive series of patients with cervical dislocation treated at two Australian centres. In Perth, 82 patients were treated by closed reduction and postural nursing. In Adelaide, 85 patients had closed reduction and early surgical stabilisation by interbody fusion. There were 46 bilateral dislocations, 101 unilateral dislocations, and 20 anterior subluxations. On admission 30 patients had complete tetraplegia, 17 incomplete tetraplegia, and 120 had minimal or no neurological loss. Our results indicated that closed manipulation under general anaesthesia is a safe and effective means of reduction in the acute stage. There was a high mortality rate for acute surgery in patients with complete tetraplegia. Early surgical stabilisation by dowel fusion reduced bed and hospital stay in patients with no neurological loss, but seemed to impair neurological recovery in patients with a neurological deficit on admission. Conservative management after reduction of bilateral dislocation or anterior subluxation led to a higher incidence of instability in patients with minimal or no neurological loss; in such cases surgery to stabilise the injured segment is indicated.


The Journal of Bone & Joint Surgery British Volume
Vol. 38-B, Issue 4 | Pages 855 - 861
1 Nov 1956
Griffiths E

1. An example of haematogenous tuberculous lesion of striated muscle is described.

2. Its rarity is stressed and pathological details described.

3. Some of the theories for the refractory reaction of muscle tissue to tuberculous infection are discussed, and experimental work is reviewed.

4. The prognosis, treatment, and the relationship of the disease to trauma are considered.