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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 76 - 76
1 Jul 2012
Panteli M Dahabreh Z Howell F
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Introduction

We examined the effect on blood loss of two standardised intravenous bolus doses of 500 mg of Tranexamic Acid, a fibrinolytic inhibitor that reduces blood loss following Knee Arthroplasty (KA).

Materials and Methods

Our study included one hundred consecutive patients undergoing primary cemented KA, who received two standarised bolus doses of 500 mg of Tranexamic Acid. The first dose was administered at induction to anaesthetic and the second dose was administered just before the closure. Data, which included Haemoglobin (Hb), Haematocrit (Hct), Length of Hospital Stay (LOS) and complications, was collected prospectively by an independent observer. Routine blood tests were done on the 1st or 2nd post-operative day.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 65 - 65
1 Jul 2012
Dahabreh Z Stewart T Stone M
Full Access

Purpose of the Study

This study aims at investigating the effect of application time of bone cement on the cement-bone interface strength in two types of commercially available bone cements, Cement-A and Cement-B.

Materials and methods

Cement-A and Cement-B were applied to cancellous bone specimens at two different times; 2 and 4 minutes (min). The bone specimens were formulated from bovine bone. Specimens were loaded to failure and the force at which the cement-bone interface failed was recorded. The shear strength of the cement-bone interface was calculated by dividing the force at failure by the cross-sectional surface area of the cement-bone interface.