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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 237 - 237
1 Sep 2012
Loughenbury P Owais A Taylor L Macfie J Andrews M
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Introduction

Obesity has been associated with higher complication rates and poorer outcomes following joint replacement surgery. Body mass index (BMI) is a simple index of body composition and forms part of preoperative assessment. It does not take into account the proportion of lean mass and body fat and can give a false impression of body composition in healthy manual workers. A more accurate measure of body composition is available using non-invasive bioimpedance methods. This study aims to identify whether BMI provides an accurate measure of body fat composition in patients awaiting lower limb arthroplasty surgery.

Methods

Consecutive patients attending for pre-assessment clinic prior to total knee and hip replacement surgery were examined. All patients had their BMI calculated and underwent bioimpedance testing using a bedside Bodystat 1500 scanner (Bodystat, UK).


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 58 - 58
1 Jun 2012
El-Osta B Ghoz A Andrews M
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Introduction

The Oxford Knee Score is a well validated, commonly used scoring system. Previous studies have suggested that the score is influenced by demographic differences between patients in particular the functional component more than the pain and clinical components. The aim of this study was to further assess this using a large number of patients.

Methods

The pre, 3 months and 12 months post-surgical Oxford Knee Scores were collected from 1492 patients from five distinct demographic locations undergoing total knee arthroplasty over twelve years under the care of 8 different consultants. A total of 735 patients had complete data sets. The scores were than analysed to test whether age, postcode, sex or consultant in charge had any significant effects on the outcome.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 6 - 6
1 Mar 2012
El-Osta B Cook A Ghoz A Andrews M
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Introduction

The Oxford Knee Score is a well validated, commonly used scoring system. Previous studies have suggested that the score is influenced by demographic differences between patients in particular the functional component more than the pain and clinical components. The aim of this study was to further assess this using a large number of patients.

Methods

The pre, 3 months and 12 months post-surgical Oxford Knee Scores were collected from 1492 patients from five distinct demographic locations undergoing total knee arthroplasty over twelve years under the care of 8 different consultants. A total of 735 patients had complete data sets. The scores were than analysed to test whether age, postcode, sex or consultant in charge had any significant effects on the outcome.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 537 - 537
1 Aug 2008
Chandran P Mereddy PKR Azzabi M Andrews M Bradley JG
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Aim: To compare the difference in periprosthetic bone density between cemented and uncemented total hip replacement at a minimum follow up of 10 years.

Patients and methods: We looked at a cohort of 17 patients who have had bilateral total hip replacement with cemented Charnley total hip on one side and uncemented Furlong total hip on the other side between 1984 and 1994 (minimum follow up 10 years). Harris and Oxford hip scores were used to determine the function, SF 36 was used to measure quality of life and Dual energy X-Ray absorptiometry (DEXA) scan was used to quantify bone mineral density adjacent to the prosthesis. The results from the DEXA scan for cemented and the uncemented hips were analysed using Paired samples two tailed t-tests. To compare the Harris hip scores, a non-parametric Wilcoxon test was used. Pearson correlations were carried out to examine the relationship between the bone density measures (averaged for each zone) and the quality of life measures.

Results: Bone mineral density was higher on the Furlong side in Gruen Zones 2, 3, 5 and 6 of the proximal femur and DeLee Charnley Zone 1 of the acetabulum. In all other zones there was no statistical difference. Comparison of Harris hip scores and Oxford hip scores showed no statistically significant difference between the two hips (p = 0.108). Age is negatively correlated with bone density in Gruen zones 6 and 7 and acetabular zones 2 and 3.

Conclusion: Bone density is better preserved around the uncemented HAC coated stem compared to the Charnley cemented stem.


The Journal of Bone & Joint Surgery British Volume
Vol. 83-B, Issue 8 | Pages 1195 - 1201
1 Nov 2001
McGrath LR Shardlow DL Ingham E Andrews M Ivory J Stone MH Fisher J

We have examined 26 retrieved, failed titanium-alloy femoral stems. The clinical details, radiological appearances and the histology of the surrounding soft tissues in each patient were also investigated.

The stems were predominantly of the flanged design and had a characteristic pattern of wear. A review of the radiographs showed a series of changes, progressive with time. The first was lateral debonding with subsidence of the stem. This was followed by calcar resorption and fragmentation or fracture of the cement. Finally, osteolysis was seen, starting with a radiolucency at the cement-bone interface and progressing to endosteal cavitation.

Three histological appearances were noted: granulomatous, necrobiotic and necrotic. We suggest that an unknown factor, possibly related to the design of the stem, caused it to move early. After this, micromovement at the cement-stem interface led to the generation of particulate debris and fracture of the cement. A soft-tissue reaction to the debris resulted in osteolysis and failure of fixation of the prostheses.