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Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 412 - 412
1 Sep 2009
Gulati A Jenkins C Chau R Pandit HG Dodd CAF Price AJ Simpson DJ Beard DJ Gill HS Murray DW
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Purpose: Varus deformity after total knee replacement (TKR) is associated with poor outcome. This aim of this study was to determine whether the same is true for medial unicompartmental arthroplasty (UKA).

Methods: 158 patients implanted with the Oxford UKA, using a minimally invasive approach, were studied prospectively for five years. Leg alignment was measured with a long-arm goniometer referenced from Anterior Superior Iliac Spine, centre of patella and centre of ankle. Patients were grouped according to the American Knee Society Score (AKSS). Group A: > 0° varus (n=13, 8.2%); Group B: 0 to 4° valgus (n=39, 24.7%); Group C: 5–10° valgus (normal alignment, n=106, 67.12%). Comparisons were made between the three groups in terms of the absolute and the change in Oxford Knee Score (OKS) and AKSS over the five year period, and the presence of radiolucency.

Results: There was no significant difference in any outcome measure except for Objective-AKSS (p< 0.001). The means and standard deviations of the ΔOKS for the groups were:

24 ± 5,

22 ± 10, and

22 ± 9 and for Objective-AKSS were 84 ± 12, 82 ± 15 and 91 ± 11 respectively.

The frequency of five year radiolucency for the groups A, B, and C were 42%, 35%, and 45% respectively.

Conclusion: The aim of the Oxford UKA is to restore knee kinematics and thus knee alignment to the pre-disease state. Therefore, as demonstrated by this study, about 30% of patients have varus alignment. This study also demonstrates that post-operative varus alignment does not compromise the outcome. The only score which did show worse outcome was the Objective-AKSS. This is because 10 or 20 points are deducted for varus alignment, which is not appropriate following UKA. Therefore, AKSS in its present form is not a reliable tool for assessment of UKA.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 421 - 421
1 Sep 2009
Chau R Pandit HG Gulati A Gray H Beard DJ Gill HS Dodd CAF Price AJ Murray DW
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Purpose: To identify associative factors for radiolucency (RL) under the tibial component following the Oxford unicompartmental arthroplasty (UKA), and to evaluate its effect on clinical outcome scores.

Method: One hundred and sixty-one knees which had undergone primary Phase 3 medial Oxford UKA were included. Fluoroscopic radiography films were assessed at five years post-operatively for areas of tibial RL. The two groups of patients, with and without RL, were compared to

patients’ pre-operative demographics for age, weight, height, BMI,

intra-operative variables such as the operating surgeon (n=2), insert and component sizes,

post-operative varus/valgus deformity, and

clinical outcome, assessed by the change in Oxford knee (OKS) and Tegner (TS) scores, from before surgery to five-year post-operatively.

Results: 101 (62%) knees were found to have tibial RL. All RL were categorised as physiological or they were < 1mm thick, with sclerotic margins and non-progressive. No statistical difference was found between knees with RL and those without, in terms of pre-operative demographics, intra- or post-operative factors, and clinical outcome scores (p> 0.1 in all variables).

Discussion: Radiolucency (RL) under the tibial component is a common finding following the Oxford UKA. Many theories have been proposed to explain the cause of RL, such as poor cementing, osteonecrosis, micromotion, and thermal necrosis. However, the true aetiology and clinical significance remain unclear. We attempted to address this.

We found no significant relationship between physiological RL, pre-operative demographics, intra-operative variables and clinical outcome scores in this study. Tibial RL remains a common finding following the Oxford UKA yet we do not know why it occurs but in the medium term, clinical outcome is not influenced by RL. In particular, it is not a sign of loosening. Physiological RL can therefore be ignored even if associated with adverse symptoms following the Oxford UKA.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 7 | Pages 928 - 934
1 Jul 2009
Palan J Gulati A Andrew JG Murray DW Beard DJ

Balancing service provision and surgical training is a challenging issue that affects all healthcare systems. A multicentre prospective study of 1501 total hip replacements was undertaken to investigate whether there is an association between surgical outcome and the grade of the operating surgeon, and whether there is any difference in outcome if surgeons’ assistants assist with the operation, rather than orthopaedic trainees. The primary outcome measure was the change in the Oxford hip score (OHS) at five years. Secondary outcomes included the rate of revision and dislocation, operating time, and length of hospital stay.

There was no significant difference in ΔOHS or complication rates between operations undertaken by trainers and trainees, or those at which surgeons’ assistants and trainees were the assistant. However, there was a significant difference in the duration of surgery, with a mean reduction of 28 minutes in those in which a surgeons’ assistant was the assistant.

This study provides evidence that total hip replacements can be performed safely and effectively by appropriately trained surgeons in training, and that there are potential benefits of using surgeons’ assistants in orthopaedic surgery.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 7 | Pages 896 - 902
1 Jul 2009
Gulati A Chau R Pandit HG Gray H Price AJ Dodd CAF Murray DW

Narrow, well-defined radiolucent lines commonly observed at the bone-implant interface of unicompartmental knee replacement tibial components have been referred to as physiological radiolucencies. These should be distinguished from pathological radiolucencies, which are poorly defined, wide and progressive, and associated with loosening and infection. We studied the incidence and clinical significance of tibial radiolucent lines in 161 Oxford unicondylar knee replacements five years after surgery. All the radiographs were aligned with fluoroscopic control to obtain views parallel to the tibial tray to reveal the tibial bone-implant interface.

We found that 49 knees (30%) had complete, 52 (32%) had partial and 60 (37%) had no radiolucent lines. There was no relationship between the incidence of radiolucent lines and patient factors such as gender, body mass index and activity, or operative factors including the status of the anterior cruciate ligament and residual varus deformity. Nor was any statistical relationship established between the presence of radiolucent lines and clinical outcome, particularly pain, assessed by the Oxford Knee score and the American Knee Society score.

We conclude that radiolucent lines are common after Oxford unicompartmental knee replacement but that their aetiology remains unclear. Radiolucent lines were not a source of adverse symptoms or pain. Therefore, when attempting to identify a source of postoperative pain after Oxford unicompartmental knee replacement the presence of a physiological radiolucency should be ignored.


The Journal of Bone & Joint Surgery British Volume
Vol. 91-B, Issue 4 | Pages 469 - 474
1 Apr 2009
Gulati A Pandit H Jenkins C Chau R Dodd CAF Murray DW

Varus malalignment after total knee replacement is associated with a poor outcome. Our aim was to determine whether the same was true for medial unicompartmental knee replacement (UKR). The anatomical leg alignment was measured prospectively using a long-arm goniometer in 160 knees with an Oxford UKR. Patients were then grouped according to their mechanical leg alignment as neutral (5° to 10° of valgus), mild varus (0° to 4° of valgus) and marked varus (> 0° of varus). The groups were compared at five years in terms of absolute and change in the Oxford Knee score, American Knee Society score and the incidence of radiolucent lines.

Post-operatively, 29 (18%) patients had mild varus and 13 (8%) had marked varus. The mean American Knee Society score worsened significantly (p < 0.001) with increasing varus. This difference disappeared if a three-point deduction for each degree of malalignment was removed. No other score deteriorated with increasing varus, and the frequency of occurrence of radiolucent lines was the same in each group.

We therefore conclude that after Oxford UKR, about 25% of patients have varus alignment, but that this does not compromise their clinical or radiological outcome. Following UKR the deductions for malalignment in the American Knee Society score are not justified.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_III | Pages 432 - 432
1 Oct 2006
Gulati A Shardlow D
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The optimum approach for Total Hip Arthroplasty is hotly debated. Many surgeons, especially the newly trained, have been wary of the posterior approach because of higher reported rates of dislocation.

We analysed 137 consecutive patients who underwent Primary Total Hip Replacement for Osteoarthritis during the first three years of practice of a newly appointed consultant with an interest in hip and knee arthroplasty. All surgeries were either performed by or under the direct supervision of the senior author. The posterior capsule and short external rotators were reattached to the Greater Trochanter as a routine.

Data was gathered prospectively by proforma for all the patients, one at the time of operation and one each at 3 months and 12 months from the surgery. 4 patients died due to causes unrelated to their arthroplasty (2.9%) and 6 patients (4.3%) were lost to follow up.

The patients were grouped into A, B and C depending on involvement of one hip, both hips and multiple joint diseases respectively and the patients were analysed for pain scores (1–6), function scores (1–6) and satisfaction levels (1–5) after the surgery. All the complications during and after surgery were noted, and special emphasis was laid on the incidence of dislocation, and factors contributing to it. The results were compared with the incidence reported in the literature for posterior and other approaches.

The results were gratifying and were comparable with major series of Total Hip Replacement via the posterior approach. Only one patient (0.7%) had a dislocation. This occurred during the index admission when the patient sat down on a ward toilet without a raised toilet seat. The hip was reduced under General Anaesthesia and he had no problem thereafter. 122 patients (96%) had no pain or minimal pain not limiting the activity after the surgery but 5 patients (4%), 3 from Group C had activity related pain or pain at rest. 93 patients (73%) were walking without a stick after surgery and 34 patients (27%) were using a stick for extra safety. 5 patients (4%) had superficial infection which settled with antibiotics and one patient (0.7%) had deep infection which required a Revision hip surgery. 6 patients developed Deep Vein Thrombosis (4.7%) and one patient (0.7%) had Pulmonary Embolism but all the patients returned to good function after treatment. One patient (0.7%) developed transient Sciatic nerve palsy but recovered completely.

We conclude that the posterior approach, already known to cause less blood loss and to allow optimum component positioning and alignment, is compatible with a low overall rate of early complications. Specifically, the dislocation rate is low and comparable with large series performed by approaches traditionally considered to carry a lower rate of dislocation.