The last two decades have seen remarkable technological advances in total hip arthroplasty (THA) implant design. Porous ingrowth surfaces and highly crosslinked polyethylene (HXLPE) have been expected to dramatically improve implant survivorship. The purpose of the present study was to evaluate survival of contemporary cementless acetabular components following primary THA. 16,421 primary THAs performed for osteoarthritis between 2000 and 2019 were identified from our institutional total joint registry. Patients received one of 12 contemporary cementless acetabular designs with HXLPE liners. Components were grouped based on ingrowth surface into 4 categories: porous titanium (n=10,952, mean follow-up 5 years), porous tantalum (n=1223, mean follow-up 5 years), metal mesh (n=2680, mean follow-up 6.5 years), and hydroxyapatite (HA) coated (n=1566, mean follow-up 2.4 years). Kaplan-Meier analyses were performed to assess the survivorship free of acetabular revision. A historical series of 182 Harris-Galante-1 (HG-1) acetabular components was used as reference. The 15-year survivorship free of acetabular revision was >97% for all 4 contemporary cohorts. Compared to historical control, porous titanium (HR 0.06, 95% CI 0.02–0.17, p<0.001), porous tantalum (HR 0.09, 95%CI 0.03–0.29, p<0.001), metal mesh (HR 0.11, 95%CI 0.04–0.31, p<0.001), and HA-coated (HR 0.14, 95%CI 0.04–0.48, p=0.002) ingrowth surfaces had significantly lower risk of any acetabular revision. There were 16 cases (0.1%) of acetabular aseptic loosening that occurred in 8 (0.07%) porous titanium, 5 (0.2%) metal mesh, and 3 (0.2%) HA-coated acetabular components. 7 of the 8 porous titanium aseptic loosening cases occurred in one known problematic design. There were no cases of aseptic loosening in the porous tantalum group. Modern acetabular ingrowth surfaces and HXLPE liners have improved on historical results at the mid-term. Contemporary designs have extraordinarily high revision-free survivorship, and aseptic loosening is now a rare complication. At mid-term follow-up, survivorship of contemporary uncemented acetabular components is excellent and aseptic loosening occurs in a very small minority of patients

Aims

The aim of this study is to report the long-term outcomes of instrumented femoral revisions with impaction allograft bone grafting (IBG) using the X-change femoral revision system at 30 years after introduction of the technique.

Aims

The aim of this study was to determine the outcome of all primary total hip arthroplasties (THAs) and their subsequent revision procedures in patients aged under 50 years performed at our institution.

Aims

The main aims were to identify risk factors predictive of a radiolucent line (RLL) around the acetabular component with an interface bioactive bone cement (IBBC) technique in the first year after THA, and evaluate whether these risk factors influence the development of RLLs at five and ten years after THA.

Aims

Bone stock restoration of acetabular bone defects using impaction bone grafting (IBG) in total hip arthroplasty may facilitate future re-revision in the event of failure of the reconstruction. We hypothesized that the acetabular bone defect during re-revision surgery after IBG was smaller than during the previous revision surgery. The clinical and radiological results of re-revisions with repeated use of IBG were also analyzed.

Aims

Various surgical techniques have been described for total hip arthroplasty (THA) in patients with Crowe type III dislocated hips, who have a large acetabular bone defect. The aim of this study was to evaluate the long-term clinical results of patients in whom anatomical reconstruction of the acetabulum was performed using a cemented acetabular component and autologous bone graft from the femoral neck.

Cementless knee arthroplasty has seen a recent resurgence in popularity due to conceptual advantages, including improved osseointegration providing biological fixation, increased surgical efficiency, and reduced systemic complications associated with cement impaction and wear from cement debris. Increasingly younger and higher demand patients are requiring knee arthroplasty, and as such, there is optimism cementless fixation may improve implant survivorship and functional outcomes.

Compared to cemented implants, the National Joint Registry (NJR) currently reports higher revision rates in cementless total knee arthroplasty (TKA), but lower in unicompartmental knee arthroplasty (UKA). However, recent studies are beginning to show excellent outcomes with cementless implants, particularly with UKA which has shown superior performance to cemented varieties. Cementless TKA has yet to show long-term benefit, and currently performs equivalently to cemented in short- to medium-term cohort studies. However, with novel concepts including 3D-printed coatings, robotic-assisted surgery, radiostereometric analysis, and kinematic or functional knee alignment principles, it is hoped they may help improve the outcomes of cementless TKA in the long-term. In addition, though cementless implant costs remain higher due to novel implant coatings, it is speculated cost-effectiveness can be achieved through greater surgical efficiency and potential reduction in revision costs. There is paucity of level one data on long-term outcomes between fixation methods and the cost-effectiveness of modern cementless knee arthroplasty.

This review explores recent literature on cementless knee arthroplasty, with regards to clinical outcomes, implant survivorship, complications, and cost-effectiveness; providing a concise update to assist clinicians on implant choice.

Cite this article: Bone Jt Open 2021;2(1):48–57.

Aims

The aim of this study was to analyze the effect of a lateral rim mesh on the survival of primary total hip arthroplasty (THA) in young patients, aged 50 years or younger.

Femoral revision after cemented total hip arthroplasty (THA) might include technical difficulties, following essential cement removal, which might lead to further loss of bone and consequently inadequate fixation of the subsequent revision stem. Bone loss may occur because of implant loosening or polyethylene wear, and should be addressed at time of revision surgery. Stem revision can be performed with modular cementless reconstruction stems involving the diaphysis for fixation, or alternatively with restoration of the bone stock of the proximal femur with the use of allografts. Impaction bone grafting (IBG) has been widely used in revision surgery for the acetabulum, and subsequently for the femur in Paprosky defects Type 1 or 2. In combination with a regular length cemented stem, impaction grafting allows for restoration of femoral bone stock through incorporation and remodeling of the proximal femur. Cavitary bone defects affecting the metaphysis and partly the diaphysis leading to a wide femoral canal are ideal indications for this technique. In case of combined segmental-cavitary defects a metal mesh is used to contain the defect which is then filled and impacted with bone grafts. Cancellous allograft bone chips of 2 to 4 mm size are used, and tapered into the canal with rods of increasing diameters. To impact the bone chips into the femoral canal a dummy of the dimensions of the definitive cemented stem is inserted and tapped into the femur to ensure that the chips are firmly impacted. Finally, a standard stem is implanted into the newly created medullary canal using bone cement. To date several studies from Europe have shown favorable results with this technique, with some excellent long-term results reported. Advantages of IBG include the restoration of the bone stock in the proximal femur, the use of standard length cemented stems and preserving the diaphysis for re-revision. As disadvantages of the technique: longer surgical time, increased blood loss and the necessity of a bone bank can be mentioned

Aims

The purpose of this retrospective study was to evaluate the minimum five-year outcome of revision total hip arthroplasty (THA) using the Kerboull acetabular reinforcement device (KARD) in patients with Paprosky type III acetabular defects and destruction of the inferior margin of the acetabulum.

Using the Mayo Clinic definition (>62mm in women and >66mm in men), the “jumbo acetabular component” is the most successful method for acetabular revisions now, even in hips with severe bone loss. There are numerous advantages: surface contact is maximised; weight-bearing is distributed over a large area of the pelvis; the need for bone grafting is reduced; and usually, hip center of rotation is restored. The possible disadvantages of jumbo cups include: may not restore bone stock; may ream away posterior column or wall; screw fixation required; the possibility of limited bone ingrowth and late failure; and a high rate of dislocation due to acetabular size:femoral head ratio. The techniques for a successful jumbo revision acetabular component involve: sizing-“reaming” of the acetabulum, careful impaction to achieve a “press-fit”, and multiple screw fixation. We recommend placement of an ischial screw in addition to dome and posterior column screw fixation. Cancellous allograft is used for any cavitary defects. The contra-indications for a jumbo acetabular cup are: pelvic dissociation; inability to get a rim fit; and inability to get screw fixation. If stability cannot be achieved with the jumbo cup alone, then use of augment(s), bulk allograft, or cup-cage construct should be considered. Using titanium fiber-metal mesh components, we reported the 15-year survival of 129 revisions. There was 3% revision for deep infection and only 3% revision for aseptic loosening. There were 13 reoperations for other reasons: wear, lysis, dislocation, femoral loosening, and femoral fracture fixation. The survival was 97.3% at 10 years, but it dropped to 82.8% at 15 years. Late loosening of this fiber metal mesh component is likely related to polyethylene wear and loss of fixation. Dislocation is the most common complication of jumbo acetabular revisions, approximately 10%, and these are multifactorial in etiology and often require revision. Based on our experience, we now recommend use of an acetabular component with an enhanced porous coating (tantalum), highly crosslinked polyethylene, and large femoral heads or dual mobility for all jumbo revisions

Femoral revision in cemented THA might include some technical difficulties, based on loss of bone stock and cement removal, which might lead to further loss of bone stock, inadequate fixation, cortical perforation or consequent fractures. Femoral impaction grafting, in combination with a primary cemented stem, allows for femoral bone restoration due to incorporation and remodelling of the allograft bone by the host skeleton. Historically it has been first performed and described in Exeter in 1987, utilizing a cemented tapered polished stem in combination with morselised fresh frozen bone grafts. The technique was refined by the development of designated instruments, which have been implemented by the Nijmegen group from Holland. Indications might include all femoral revisions with bone stock loss, while the Endo-Clinic experience is mainly based on revision of cemented stems. Cavitary bone defects affecting meta- and diaphysis leading to a wide or so called “drain pipe” femora, are optimal indications for this technique, especially in young patients. Contraindications are mainly: septical revisions, extensive circumferential cortical bone loss and noncompliance of the patient. Generally, the technique creates a new endosteal surface to host the cemented stem by reconstruction of the cavitary defects with impacted morselised bone graft. This achieves primary stability and restoration of the bone stock. It has been shown, that fresh frozen allograft shows superior mechanical stability than freeze-dried allografts. Incorporation of these grafts has been described in 89%. Technical steps include: removal of failed stem and all cement, reconstruction of segmental bone defects with metal mesh (if necessary), preparation of fresh frozen femoral head allografts with bone mill, optimal bone chip diameter 2–5 mm, larger chips for the calcar area (6–8 mm), insertion of an intramedullary plug including central wire, 2 cm distal the stem tip, introduction of bone chips from proximal to distal, impaction started by distal impactors over central wire, then progressive larger impactors proximal, insertion of a stem “dummy” as proximal impactor and space filler, removal of central wire, retrograde insertion of low viscosity cement (0.5 Gentamycin) with small nozzle syringe, including pressurization, and insertion of standard cemented stem. The cement mantle is of importance, as it acts as the distributor of force between the stem and bone graft and seals the stem. A cement mantle of at least 2 mm has shown favorable results. Post-operative care includes usually touch down weightbearing for 6–8 weeks, followed by 4–6 weeks of gradually increased weightbearing with a total of 12 weeks on crutches. Relevant complications include mainly femoral fractures due to the hardly impacted allograft bone. Subsidence of tapered polished implants might be related to cold flow within the cement mantle, however, could also be related to micro cement mantle fractures, leading to early failure. Subsidence should be less than 5 mm. Survivorship with a defined endpoint as any femoral revision after 10-year follow up has been reported by the Exeter group being over 90%, while survivorship for revision as aseptic loosening being above 98%. Within the last years various other authors and institutions reported about similar excellent survivorships, above 90%. In addition, a long-term follow up by the Swedish arthroplasty registry in more than 1180 patients reported a cumulative survival rate of 94% after 15 years. Impaction grafting might technically be more challenging and more time consuming than cement-free distal fixation techniques. It, however, enables a reliable restoration of bone stock which might especially become important in further revision scenarios in younger patients

Femoral revision in cemented THA might include some technical difficulties, based on loss of bone stock and cement removal, which might lead to further loss of bone stock, inadequate fixation, cortical perforation or consequent fractures. Femoral impaction grafting, in combination with a primary cemented stem, allows for femoral bone restoration due to incorporation and remodeling of the allograft bone by the host skeleton. Historically, it has been first performed and described in Exeter in 1987, utilizing a cemented tapered polished stem in combination with morselised fresh frozen bone grafts. The technique was refined by the development of designated instruments, which have been implemented by the Nijmegen group from Holland. Indications might include all femoral revisions with bone stock loss, while the ENDO-Klinik experience is mainly based on revision of cemented stems. Cavitary bone defects affecting meta- and diaphysis leading to a wide or so called “drain pipe” femora, are optimal indications for this technique, especially in young patients. Contraindications are mainly: septical revisions, extensive circumferential cortical bone loss and noncompliance of the patient. Generally the technique creates a new endosteal surface to host the cemented stem by reconstruction of the cavitary defects with impacted morselised bone graft. This achieves primary stability and restoration of the bone stock. It has been shown, that fresh frozen allograft shows superior mechanical stability than freeze-dried allografts. Incorporation of these grafts has been described in 89%. Technical steps include: removal of failed stem and all cement, reconstruction of segmental bone defects with metal mesh (if necessary), preparation of fresh frozen femoral head allografts with bone mill, optimal bone chip diameter 2 – 5 mm, larger chips for the calcar area (6 – 8 mm), insertion of an intramedullary plug including central wire, 2 cm distal to the stem tip, introduction of bone chips from proximal to distal, impaction started by distal impactors over central wire, then progressively larger impactors proximal, insertion of a stem “dummy” as proximal impactor and space filler, removal of central wire, retrograde insertion of low viscosity cement (0.5 Gentamycin) with small nozzle syringe, including pressurization, insertion of standard cemented stem. The cement mantle is of importance, as it acts as the distributor of force between the stem and bone graft and seals the stem. A cement mantle of at least 2 mm has shown favorable results. Originally the technique is described with a polished stem. We use standard brushed stems with comparable results. Postoperative care includes usually touch down weight bearing for 6–8 weeks, followed by 4–6 weeks of gradually increased weightbearing with a total of 12 weeks on crutches. Survivorship with a defined endpoint as any femoral revision after 10 year follow up has been reported by the Exeter group being over 90%. While survivorship for revision related to aseptic loosening being above 98%. Within the last years various other authors and institutions reported similar excellent survivorships, above 90%. In addition a long term follow up by the Swedish arthroplasty registry in more than 1180 patients reported a cumulative survival rate of 94% after 15 years. Impaction grafting might technically be more challenging and more time consuming than cement free distal fixation techniques. It, however, enables a reliable restoration of bone stock which might become important in further revision scenarios in younger patients

Recent advancements in biomaterial technology have created novel options for acetabular fixation in primary total hip arthroplasty (THA). For example, cementless acetabular fixation has become the preferred option, however, there is continued debate concerning whether long-term survivorship is comparable to that of cemented component fixation. Many doubts previously associated with early cementless designs have been addressed with newer features such as improved locking mechanisms, enhanced congruity between the acetabular liner and the shell, and the inclusion of highly cross-linked ultra-high molecular weight polyethylene (UHMWPE). Additionally, there has been increased utilization of new porous metals, titanium mesh, and hydroxyapatite (HA) coated implants. However, several retrieval studies have indicated that porous-coated cementless acetabular components can exhibit poor bony ingrowth. Many surgeons in Europe favor cemented fixation, where registry data is favorable for this interface. A surgeon's decision to use a cemented or cementless acetabular component is typically dependent on factors such as patient bone stock, surgical training, and experience. With the frequency of THAs expected to increase, it is particularly important for orthopaedic surgeons to be familiar with appropriate preoperative planning and component selection in an effort to achieve optimal outcomes. Therefore, this talk will outline and describe the options currently available for cementless and cemented acetabular fixation in primary total hip arthroplasty

Introduction. Hydroxyapatite and poly-L-lactide (HA/PLLA) composites are osteoconductive and biodegradable. They have already been used clinically to treat fractured bones by inducing osteosynthesis and serving as the bone filling material. During revision of total hip arthroplasty, we have grafted bone onto the bone defect and covered it with an HA/PLLA mesh instead of using a metal mesh on the non-load bearing portion of the cup (Figure 1). However, whether the interface between the HA/PLLA and the titanium alloy cup was stable remains unclear. Objectives. The purpose of this study was to determine and compare the histological osteoconductivity and osteoinductivity of HA/PLLA and titanium alloy. Methods. Semicylindrical samples (diameter: 3 mm; height: 5 mm) were fabricated from a composite unsintered-HA/PLLA containing 40% fine HA particles and from titanium alloy (Ti-6AL-4V). These two samples were combined to form one cylinder (Figure 2). Defects 3 mm in diameter were drilled into both femoral condyles of nine Japanese white rabbits, and the samples were implanted by press fitting. The rabbits were euthanized at 2, 4, 8, and 25 weeks after implantation, and undecalcified ground samples were prepared. New bone formation was examined histologically using Toluidine blue and Villanueva Goldner stains. Results. New bone formation was observed around the sample at 4 weeks, and the amount increased by 8 weeks. In addition, partial remodeling of the trabecular bones and absorption of the HA/PLLA were found at 25 weeks. Small amounts of new bone formation were found at 4 weeks between the HA/PLLA and titanium alloy materials (Figure 3: Toluidine blue stain), and the amount increased at 8 and 25 weeks. The HA/PLLA had been slightly absorbed and new bone was formed in the gap, which was close to the border between the materials, at 25 weeks. However, the amount of absorption was limited, and no new bone was found in samples where the materials were firmly in contact. Conclusions. HA/PLLA was only slight absorbed at 25 weeks, suggesting that it was stable in vivo and has good osteoconductive and osteoinductive properties. No new bone was found in the regions where the sample was stable and had no gaps between the HA/PLLA and titanium alloy, probably because there was no space for new bone to form in those regions. In contrast, new bone formation was found in gaps of more than 20 μm. Clinically, many gaps likely exist, allowing new bone formation to occur even in a stable implant. This may stabilize the HA/PLLA and titanium alloy materials for longer times. As expected, the HA/PLLA and titanium alloy were mostly stablein vivo

Purpose. The purpose of the present study is to assess 5–10 years' follow-up results after acetabular impaction bone grafting (IBG) in primary cemented total hip arthroplasty (THA) for cases with acetabular bone defect. Patients and methods. We performed 36 primary cemented THA with acetabular IBG in 33 patients between November 2004 and May 2009. As one patient died due to unrelated disease at 6 months after the surgery, 35 hips of 32 patients were included in this study. The average age at the surgery was 62.4 years, and the average follow-up period was 7.9 years (5–10 years). Diagnoses were osteoarthritis due to acetabular dysplasia in 28 hips (26 patients), Rheumatoid arthritis (RA) in 4 hips (3 patients), rapidly destructive coxopathy (RDC) in 1 hip (1 patient), idiopathic acetabular protrusion in 1 hip (1 patient), and acromegaly in 1 hip (1 patient). For clinical assessment, the Merle d'Aubigné and Postel hip score was assessed and degree of post-operative improvement was classified according to their method as very great improvement, great improvement, fair improvement, and failure. Perioperative complications were also recorded. Acetabular bone defects were assessed at the surgery and categorized using AAOS acetabular bone defect classification system. For radiological assessment, anteroposterior radiographs of the bilateral hip joints were analyzed preoperatively and post-operatively. Radiolucent lines (RLL) of more than 2 mm around the acetabular components were assessed using the DeLee and Charnley zone classification. Acetabular component loosening was assessed according to the Hodgkinson et al. classification system, and type 3 (complete demarcation line) and type 4 (migration) were classified as “loosening”. Results. The mean Merle d'Aubigné and Postel hip score improved from 9.8 points before the operation to 15.9 points at the final follow-up. Degree of post-operative improvement was assessed as “very great” in 11 hips, “great” in 23 hips and “fair” in 1 hip. Dislocation, DVT, and infection were recorded in 1 hip, 1 hip, and 1 hip, respectively. Re-operation was performed for the acute infection (without loosening) case at 5.3 years after the primary THA. Acetabular bone defects were classified as segmental defect (AAOS type I) in 29 hips, cavitary defect (AAOS type II) in 3 hips and combined segmental and cavitary defect (AAOS type III) in 3 hips. Metal meshes were used for segmental defects of 29 AAOS type I hips and 2 AAOS type III hips, and for medial wall defect of 1 AAOS III hip. On radiographic assessment, no metal device breakage was detected during the follow-up period. There were no clear lines around the cup and all cups were assessed as stable at the final follow-up. Conclusion. Acetabular impaction bone grafting in primary cemented THA is technically demanding procedure. However, postoperative functional improvement is remarkable and stable radiographic findings were achievable independent from original diagnoses. This procedure is one of useful options to restore acetabular bone deficiency in cemented primary THA for cases with acetabular bone defect

Background. Impaction bone grafting (IBG) using a circumferential metal mesh is one of the options that allow restoration of the femoral bone stock and stability of the implant in hip arthroplasty. Here we examined the clinical and radiographic outcome of this procedure with a cemented stem and analyzed experimentally the initial stability of mesh–grafted bone–cemented stem complexes. Methods. We retrospectively reviewed 6 hips (6 patients) that had undergone femoral revisions with a circumferential metal mesh, impacted bone allografts, and a cemented stem. The mean follow-up period was 2.9 years (range, 1.4–3.8 years). Hip joint function was evaluated with the Japanese Orthopaedic Association hip score, and radiographic changes were determined from radiographs. The initial resistance of cemented stem complexes to axial and rotational force was measured in a composite bone model with various segmental losses of the proximal femur. Results. The hip score improved from 50 (range, 10–84) preoperatively to a mean of 74 (range, 67–88) at the final follow-up. The overall implant survival rate was 100% at 4 years when radiological loosening or revision for any reason was used as the endpoint. No stem subsided more than 3 mm vertically within 1 year after implantation. Computed tomography showed reconstitution of the femoral canal in a metal mesh. In mechanical analyses, there was no influence on the stem stability to axial compression during the repeated axial compression test between IBG reconstruction rates. On the other hand, for IBG reconstruction rate of 66.7%, grafted bone-Sawbone juntion was buckled under the axial breaking force. In contrast, under rotational load, the rotation angles of the stainless mesh were strongly affected by the IBG reconstruction rate. Conclusions. The short-term results show good outcomes for reconstruction of proximal bone loss with impaction bone allografts and a circumferential mesh. The procedure should be applied in cases where the circumferential proximal bone loss is less than half of the stem length implanted

We present the results of 62 consecutive acetabular revisions using impaction bone grafting and a cemented polyethylene acetabular component in 58 patients (13 men and 45 women) after a mean follow-up of 27 years (25 to 30). All patients were prospectively followed. The mean age at revision was 59.2 years (23 to 82).

We performed Kaplan–Meier (KM) analysis and also a Competing Risk (CR) analysis because with long-term follow-up, the presence of a competing event (i.e. death) prevents the occurrence of the endpoint of re-revision.

A total of 48 patients (52 hips) had died or had been re-revised at final review in March 2011. None of the deaths were related to the surgery. The mean Harris hip score of the ten surviving hips in ten patients was 76 points (45 to 99).

The KM survivorship at 25 years for the endpoint ‘re-revision for any reason’ was 58.0% (95% confidence interval (CI) 38 to 73) and for ‘re-revision for aseptic loosening’ 72.1% (95% CI 51 to 85). With the CR analysis we calculated the KM analysis overestimates the failure rate with respectively 74% and 93% for these endpoints. The current study shows that acetabular impaction bone grafting revisions provide good clinical results at over 25 years.

Cite this article: Bone Joint J 2015;97-B:1338–44.

We report the clinical and radiographic outcomes of 208 consecutive femoral revision arthroplasties performed in 202 patients (119 women, 83 men) between March 1991 and December 2007 using the X-change Femoral Revision System, fresh-frozen morcellised allograft and a cemented polished Exeter stem. All patients were followed prospectively. The mean age of the patients at revision was 65 years (30 to 86). At final review in December 2013 a total of 130 patients with 135 reconstructions (64.9%) were alive and had a non re-revised femoral component after a mean follow-up of 10.6 years (4.7 to 20.9). One patient was lost to follow-up at six years, and their data were included up to this point. Re-operation for any reason was performed in 33 hips (15.9%), in 13 of which the femoral component was re-revised (6.3%). The mean pre-operative Harris hip score was 52 (19 to 95) (n = 73) and improved to 80 (22 to 100) (n = 161) by the last follow-up. Kaplan–Meier survival with femoral re-revision for any reason as the endpoint was 94.9% (95% confidence intervals (CI) 90.2 to 97.4) at ten years; with femoral re-revision for aseptic loosening as the endpoint it was 99.4% (95% CI 95.7 to 99.9); with femoral re-operation for any reason as the endpoint it was 84.5% (95% CI 78.3 to 89.1); and with subsidence ≥ 5 mm it was 87.3% (95% CI 80.5 to 91.8). Femoral revision with the use of impaction allograft bone grafting and a cemented polished stem results in a satisfying survival rate at a mean of ten years’ follow-up.

Cite this article: Bone Joint J 2015; 97-B:771–9.