Periprosthetic joint infection (PJI) is a challenging complication of any arthroplasty procedure. We reviewed our use of static antibiotic-loaded cement spacers (ABLCSs) for staged management of PJI where segmental bone loss, ligamentous instability, or soft-tissue defects necessitate a static construct. We reviewed factors contributing to their failure and techniques to avoid these complications when using ABLCSs in this context. A retrospective analysis was conducted of 94 patients undergoing first-stage revision of an infected knee prosthesis between September 2007 and January 2020 at a single institution. Radiographs and clinical records were used to assess and classify the incidence and causes of static spacer failure. Of the 94 cases, there were 19 primary total knee arthroplasties (TKAs), ten revision TKAs (varus-valgus constraint), 20 hinged TKAs, one arthrodesis (nail), one failed spacer (performed elsewhere), 21 distal femoral endoprosthetic arthroplasties, and 22 proximal tibial arthroplasties.Aims
Methods
Periprosthetic joint infections (PJIs) with prior multiple failed surgery for reinfection represent a huge challenge for surgeons because of poor vascular supply and biofilm formation. This study aims to determine the results of single-stage revision using intra-articular antibiotic infusion in treating this condition. A retrospective analysis included 78 PJI patients (29 hips; 49 knees) who had undergone multiple prior surgical interventions. Our cohort was treated with single-stage revision using a supplementary intra-articular antibiotic infusion. Of these 78 patients, 59 had undergone more than two prior failed debridement and implant retentions, 12 patients had a failed arthroplasty resection, three hips had previously undergone failed two-stage revision, and four had a failed one-stage revision before their single-stage revision. Previous failure was defined as infection recurrence requiring surgical intervention. Besides intravenous pathogen-sensitive agents, an intra-articular infusion of vancomycin, imipenem, or voriconazole was performed postoperatively. The antibiotic solution was soaked into the joint for 24 hours for a mean of 16 days (12 to 21), then extracted before next injection. Recurrence of infection and clinical outcomes were evaluated.Aims
Methods
Hydroxyapatite (HA)-coated collars have been shown to reduce aseptic loosening of massive endoprostheses following primary surgery. Limited information exists about their effectiveness in revision surgery. The aim of this study was to radiologically assess osteointegration to HA-coated collars of cemented massive endoprostheses following revision surgery. Retrospective review of osseointegration frequency, pattern, and timing to a specific HA-coated collar on massive endoprostheses used in revision surgery at our tertiary referral centre between 2010 to 2017 was undertaken. Osseointegration was radiologically classified on cases with a minimum follow-up of six months.Aims
Methods
We report the long-term clinical and radiological outcomes of a consecutive series of 200 total ankle arthroplasties (TAAs, 184 patients) at a single centre using the Scandinavian Total Ankle Replacement (STAR) implants. Between November 1993 and February 2000, 200 consecutive STAR prostheses were implanted in 184 patients by a single surgeon. Demographic and clinical data were collected prospectively and the last available status was recorded for further survival analysis. All surviving patients underwent regular clinical and radiological review. Pain and function were assessed using the American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot scoring system. The principal endpoint of the study was failure of the implant requiring revision of one or all of the components. Kaplan–Meier survival curves were generated with 95% confidence intervals and the rate of failure calculated for each year.Aims
Patients and Methods
Pelvic reconstruction after the resection of a tumour around
the acetabulum is a challenging procedure due to the complex anatomy
and biomechanics. Several pelvic endoprostheses have been introduced,
but the rates of complication remain high. Our aim was to review
the use of a stemmed acetabular pedestal cup in the management of
these patients. The study involved 48 patients who underwent periacetabular reconstruction
using a stemmed pedestal cup (Schoellner cup; Zimmer Biomet Inc.,
Warsaw, Indiana) between 2000 and 2013. The indications for treatment included
a primary bone tumour in 27 patients and metastatic disease in 21
patients. The mean age of the patients at the time of surgery was
52 years (16 to 83).Aims
Patients and Methods
Ankle replacements have improved significantly since the first reported attempt at resurfacing of the talar dome in 1962. We are now at a stage where ankle replacement offers a viable option in the treatment of end-stage ankle arthritis. As the procedure becomes more successful, it is important to reflect and review the current surgical outcomes. This allows us to guide our patients in the treatment of end-stage ankle arthritis. What is the better surgical treatment – arthrodesis or replacement?
To date, there have been few reports of the results of revisions for failed metal-on-metal hip arthroplasties (MoM HA's). These series have included relatively modest numbers, and classification of the severity of adverse local tissue reaction (ALTR) has been under-reported. In this study, early outcomes and complications are analyzed as a function of pre-operative MRI grade and intra-operative ALTR severity to determine their prognostic value. This is a retrospective review of revisions of 121 failed MoM HA's performed between 2008 and 2012. Indications for revision include ALTR (n = 97), loose cup (n = 13), and combined loose cup and ALTR (n = 11). When pre-operative MRI's were available, these were graded according to Anderson's system by 2 radiologists who were blinded to the clinical results. Intra-operative findings were graded for severity according to an ALTR classification. Post-operative complications were recorded. Correlations between pre-operative MRI grade, intra-operative ALTR classification and post-operative complications were analyzed using Spearman's rank correlation. ALTR Classification: Type 0: No abnormal fluid or pseudotumor. Peri-articular structures intact. Type 1: Abnormal fluid and/or pseudotumor. Peri-articular structures disrupted but repairable. Type 2: Abnormal fluid and/or pseudotumor. Peri-articular structures disrupted and no meaningful repair possible. Type 3: Abnormal fluid and/or pseudotumor. Peri-articular structrues disrupted, no meaningful repair possible, AND significant necrosis involving abductor muscles.Introduction:
Methods:
Achieving arthrodesis of the ankle can be difficult
in the presence of infection, deformity, poor soft tissues and bone loss.
We present a series of 48 patients with complex ankle pathology,
treated with the Ilizarov technique. Infection was present in 30
patients and 30 had significant deformity before surgery. Outcome
was assessed clinically and with patient-reported outcome measures
(Modified American Orthopaedic Foot and Ankle Society (MAOFAS) scale and
the Short-Form (SF-36)). Arthrodesis was achieved in 40 patients with the Ilizarov technique
alone and in six further patients with additional surgery. Infection
was eradicated in all patients at a mean follow-up of 46.6 months
(13 to 162). Successful arthrodesis was less likely in those with
comorbidities and in tibiocalcaneal fusion compared with tibiotalar
fusion. These patients had poor general health scores compared with the
normal population before surgery. The mean MAOFAS score improved
significantly from 24.3 (0 to 90) pre-operatively to 56.2 (30 to
90) post-operatively, but there was only a modest improvement in
general health; the mean SF-36 improved from 44.8 (19 to 66) to
50.1 (21 to 76). There was a major benefit in terms of pain relief. Arthrodesis using the Ilizarov technique is an effective treatment
for complex ankle pathology, with good clinical outcomes and eradication
of infection. However, even after successful arthrodesis general
health scores remain limited. Cite this article:
Background. Salvage procedures on the 1st MTPJ following failed arthroplasty, arthrodesis or hallux valgus surgery are difficult and complicated by bone loss. This results in shortened first ray and transfer metatarsalgia. We present our experience of using tri-cortical interposition grafts to manage this challenging problem. Methods. Between 2002 and 2009 our department performed 21, 1st MTPJ arthrodeses using a tri-cortical iliac crest interposition graft. Surgical fixation was achieved with a compact foot plate. We performed a retrospective review from the medical notes and radiographs along with American Foot and Ankle scores which were collected prospectively. We analysed the following parameters: time to radiological, requirement for further surgery, lengthening of 1st ray and any post operative complications. Results. Patient Demographics – Male: Female = 4:16. Mean age – 58 years (38-78 years). Mean follow up – 35 months (4-94 months). Indication for surgery –.
We present a series of 16 patients who have had a failed ankle arthroplasty converted to an ankle arthrodesis using a surgical technique of bone grafting with internal fixation. We describe our technique using tricortical autograft from the iliac crest to preserve length and an emphasis is placed on maintaining the malleoli and subtalar joint. A successful fusion was achieved in all cases with few complications. Our post operative AOFAS improved to a mean of 70 with good patient satisfaction and compares well to other published series. From this series and an extensive review of the literature we have found fusion rates following failed arthroplasty in patients with degenerative arthritis to be very high. In this group of patients a high fusion rate and good clinical result can be achieved when the principles of this surgical technique are adhered to. It would appear that a distinction should be made between treating patients with poor quality bone and more extensive bone loss, as is often the case with rheumatoid patients; and the patients with a non inflammatory arthropathy and better bone quality. The intramedullary nail would appear to be the preferred option in patients with inflammatory polyarthropathy where preservation of the subtalar joint is probably not of relevance as it is usually extensively involved in the disease process, and a higher rate of complications can be anticipated with internal fixation.
We report 5 cases of linked shoulder and elbow replacement (LSER) following failure of single-joint arthroplasty. Whilst total humeral replacement has been reported for treatment following resection for tumour we know of no reports of linked shoulder and elbow prostheses for arthropathy alone. Between May and December 2005, 2 patients with total elbow arthroplasty and 3 patients with total shoulder arthroplasty were revised to LSER for loosening of the long humeral stems or periprosthetic fracture. Custom-made prostheses were produced using computer-aided design and manufacture technology. There were no early complications including infection. All 5 patients reported early improvement of symptoms, with the ability to bear weight axially through the limb, restored. This technique avoids the problem of a stress riser between the stems of separate shoulder and elbow replacements and solves the problem of salvage of long-stemmed implants where no further humeral fixation is possible.
We reviewed the clinical and radiological results of 131 patients who underwent acetabular revision for aseptic loosening with impacted bone allograft and a cemented acetabular component. The mean follow-up was 51.7 months (24 to 156). The mean post-operative Merle D’Aubigné and Postel scores were 5.7 points (4 to 6) for pain, 5.2 (3 to 6) for gait and 4.5 (2 to 6) for mobility. Radiological evaluation revealed migration greater than 5 mm in four acetabular components. Radiological failure matched clinical failure. Asymptomatic radiolucent lines were observed in 31 of 426 areas assessed (7%). Further revision was required in six patients (4.5%), this was due to infection in three and mechanical failure in three. The survival rate for the reconstruction was 95.8% (95% confidence interval 92.3 to 99.1) overall, and 98%, excluding revision due to sepsis. Our study, from an independent centre, has reproduced the results of the originators of the method.
Infection after total joint arthroplasty can present a diagnostic challenge. No preoperative tests are consistently 100% sensitive and specific, so the diagnosis of infection depends on the surgeon’s judgment with respect to the clinical presentation and examination and interpretation of the results of investigations. The consequences of misdiagnosis are severe. Reimplantation of a prosthesis into an infected host bed is likely to result in persistent infection. Preoperative investigations include haematological screening tests (white blood cell count, ESR, and C-reactive protein), joint aspiration and arthrography, radiography, and radionuclide imaging studies. Intraoperative investigations include analysis of synovial fluid, gram-staining of tissue that appears inflamed, histological evaluation of frozen sections of inflamed tissue, and culture of periprosthetic tissue. The exclusion of infection as a cause of failure is imperative to determine the management of patients who need revision total joint replacement. The key to making the correct diagnosis is using not a single investigation but rather a correct combination of investigations. From 2001 to 2004 we studied 46 patients referred from various centres with prosthesis loosening. The patients had technetium and gallium scintigraphy. In 32 patients, scintigraphic studies suggested septic loosening. Of these, 21 patients also had aspirations, three intraoperative cultures and 11 both aspirations and intraoperative cultures. The remaining 11 patients had aseptic loosening and were used as a control group. In only 10 patients was sepsis proved by aspiration or culture. Our results, which show that scintigraphy has a dismal positive predictive value as a screening test and a good negative predictive value, concur with the current literature.
Introduction. Pathophysiology of glenohumeral arthritis differs depending upon type of arthritis. Osteoarthritis. Post-traumatic arthritis. Inflammatory arthritis (i.e. RA). Arthritis of instability. Crystalline arthritis (Milwaukee shoulder, cuff tear arthropathy). Avascular necrosis. Natural history as well as response to treatment are both pathology dependent. Soft-tissue involvement. Rotator cuff tear. Soft tissue contracture. Secondary osseous deformity. Regional osteopenia. Glenoid wear (concentric versus eccentric). Humeral collapse. Surgical options. Joint-sparing techniques. Arthroscopic capsular release/ joint debridement/synovectomy. Open debridement, subscapularis lengthening. Open capsular interposition. Osteotomy. Glenoid. Humeral. Cartilage transplantation. Arthrodesis. Resection arthroplasty. Joint replacement. Unconstrained. Hemiarthroplasty. Total shoulder replacement. Constrained. Joint-sparing Techniques. These techniques are only useful in patients with early changes or who are too young and active for joint replacement. Arthroscopic debridement or capsular release. Young patients. Normal joint alignment. Severe asymmetric capsular contracture (i.e. arthritis of instability). Open debridement. Large humeral osteophytes. Subscapularis lengthening. Open capsular interposition. Lateral edge of anterior capsule sutured to posterior labrum. Less severe degrees of contracture, subscapularis must be repaired anatomically. Osteotomy. Only useful in situations where there is abnormal humeral or glenoid alignment. Glenoid – posterior opening wedge for osteoarthritis in combination with posterior glenoid hypoplasia or increased retroversion. Humeral – most useful for post-fracture deformity (i.e. varus of the surgical neck). Cartilage Transplantation. Very early experience and really only attempted in any numbers in the knee. Chondrocyte transplantation very expensive and tedious. Currently, the most popular techniques involve transplanting plugs or cores of articular cartilage, subchondral bone, and cancellous bone. Autograft- harvest from non-weight-bearing or less weight-bearing area the same or different bone. Lateral femoral condyle. Posterolateral humeral head. Allograft. Early attempts limited by chondrocyte viability after harvest. Improved processing techniques have recently improved chondrocyte survival to 60–70%. Offers the desirable option of being able to preoperatively match radii of curvature of implant to donor site. Arthrodesis. Fortunately, rarely indicated. Patients miss the ability to rotate the humerus. Indications. Brachial plexus injury. Combined deltoid and rotator cuff deficiency. Young heavy labourer. Sepsis. Severe bone loss. Requires functional trapezius and serratus anterior. Resectional Arthroplasty (Jones Procedure). Even more rarely indicated than arthrodesis. Function is better if rotator cuff is attached to proximal humerus. Indications. Sepsis.