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The Bone & Joint Journal

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The Journal of Bone & Joint Surgery British Volume
Vol. 51-B, Issue 1 | Pages 148 - 155
1 Feb 1969
Lindholm R Lindholm S Liukko P Paasimaki J Isokääntä S Rossi R Auti0 E Tamminen E

1. Experimental fracture callus in rats contains mast cells as a normal morphological element.

2. The mast cell count undergoes peculiar variations in the normal course of events in experimentally delayed or accelerated bone repair.

3. A hypothesis is presented in which the tissue mast cell granules are regarded as calcium transporters in the mineral phase of callus formation, a process probably corresponding to Selye's concept of "mastocalciphylaxis" and "mastocalcergy."