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Bone & Joint Research
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Bone & Joint Research
Vol. 10, Issue 9 | Pages 619 - 628
27 Sep 2021
Osteoblast function in patients with idiopathic osteonecrosis of the femoral head
Maestro-Paramio L García-Rey E Bensiamar F Saldaña L
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Aims

To investigate whether idiopathic osteonecrosis of the femoral head (ONFH) is related to impaired osteoblast activities.

Methods

We cultured osteoblasts isolated from trabecular bone explants taken from the femoral head and the intertrochanteric region of patients with idiopathic ONFH, or from the intertrochanteric region of patients with osteoarthritis (OA), and compared their viability, mineralization capacity, and secretion of paracrine factors.