Purpose of the study: Management of the spinal neuroarthropathy of Charcot’s disease is recommended. Vertebral fusion should be extensive and often circumferential. The natural history of this disease, often diagnosed late, is poorly understood and the results of functional treatments not well studied. The purpose of this study was to describe the elements motivating surgical abstention and to analyse the natural course of the vertebral lesions.

Material and methods: The diagnosis of spinal neuroarthropathy was established in seven patients from 1997 to 2007. Six has paraplegia and one female patient Friedrich ataxia. The initial neurological disease was known for 18 years on average before diagnosis of the spinal neuroarthropathy. The management decision was based on patient motivation, comorbid conditions, and successive functional, clinical and imaging assessments. The patients were classed by the progression of vertebral destruction. Four patients had a non-evolving destruction, two with a stable spine and two with spinal hypermobility.

Results: The spinal stability, the absence of progression of the spinal neuroarthropathy, and in certain cases the presence of an ossification process were determining in deciding to abstain from surgery. Despite the collapse of the trunk, surgical abstention was decided for two patients basically because of the loss of spinal mobility resulting from the arthrodesis. For three other patients with progressing spinal lesions, the presence of comorbid factors (major risk of infection), patient refusal of the risk of temporary or definitive loss of function were the reasons surgery was decided against.

Discussion: According to the literature, it is assumed that abstention from surgery will invariably lead to neurological or infectious complications and even patient death. We did not observe these events in our series. The major surgery exposes to a risk of failure; certain authors have reported a complication rate of 60% and others have had 40% repeat operations. The instability induced by the spinal neuroarthropathy can be considered providential by the patient. The fact that several patients declined surgery because of the fear of worsening their handicap after arthrodesis is noteworthy. Simulation with a rigid corset was determining. The spinal neuroarthropathy does not appear to be a continuous destructive process but its natural history is not well known. Predictive elements were not identified in this study.

Conclusion: Charcot’s spinal neuroarthropathy is a challenging condition in frail patients. Disease progression, comorbid conditions, and multidisciplinary functional assessments are needed for adequate management and decision making.

Purpose: Prosthetic replacement of the ankle joint is a controversial issue. Minimally invasive noncemented third-generation implants with a third component have enabled improved clinical results and prolonged mid-term implant survival. These results authorise prosthetic implantation as an alternative to arthrodesis in selected patients. New developments in prosthesis concepts and design, aimed at overcoming the insufficient results of earlier implants, require early validation with a prospective clinical and radiological follow-up. The objective of this work was to present the mid-term results with the SALTO prosthesis implanted in 42 patients.

Material and methods: Forty-two SALTO prostheses implanted between February 1997 and December 2000 were followed prospectively for two to six years. The implant design, which mimics the anatomic asymmetry of the talar dome, uses a mobile polyethylene insert and optional fibular resurfacing for optimal primary and long-term stabilisation. Data were collected prospectively using a computer database which provides the AOFAS score. Metrological analysis of the digitalized x-rays (AP, lateral and stress) were used to study the precision of the insertion, implant stability, and prosthesis kinematics. Posttraumatic osteoarthritis predominated (n=29) in this series. Mean age was 54 years (30–79).

Results: None of the patients were lost to follow-up. Three patients had a revision procedure for arthrodesis (persistent pain in two and sepsis in one). The clinical score was excellent or good in 88% of patients. The mean clinical score was 20.5 points preoperatively and 70 points at last follow-up. The radiological analysis demonstrated the precision of the insertion technique and did not disclose any evidence of significant implant mobilisation with time. There were no failures related to the lateral malleolar implant (n=12). Radiographically, mean ankle movement was 15.2–23°. Changes in the periprosthetic bone were noted.

Discussion: The quality of the results with the prosthesis under study and the short- and mid-term stability enable envisaging implantation when the local or regional anatomic conditions suggest arthrodesis would produce unsatisfactory results. The improvement in function (exceptionally total recovery) remains difficult to predict. Further follow-up of these patients is needed.

Purpose: The purpose of this work was to evaluate the mid-term clinical and radiological outcome of a homogeneous and continuous series of third-generation total ankle prostheses (resurfacing, cylindric, noncemented, triple-compartment).

Material and methods: From March 1990 to June 1996, 26 patients aged 57 years (32–73) were treated with a New Jersey LCS (n=5) or Buechel-Pappas (n=21) prosthesis. Most of the patients (n=21) had a posttraumatic ankle. Preoperatively, mean ankle motion was 17°. The AOFAS score was used for the clinical assessment. The position of the prosthesis and its stability over time were assessed on the x-rays together with the insert, the bone-prosthesis interface, the bone structure and periprosthetic ossifications.

Results: Intra and postoperative complications were malleolar fracture (n=5), haematoma (n=1), late wound healing (n=1), insert instability (n=2), and medial malleolar conflict (n=1) requiring reoperation with preservation of the implant. At mean follow-up of seven years, two patients had died and one was lost to follow-up. Three had an arthrodesis: failed fixation at two years, secondary talar mobilisation at seven years, and secondary infection at eight years. For the other twenty patients: the AOFAS score was poor for two patients (including one with patent wear), fair in two, and good in 16. Mean joint motion at last follow-up was 24°. Radiographically, there were no significant changes in the position of the tibial and talar elements. Anchorage of the tibial element was fibrous in half of the patients and ossesous in the other half. A macro defect aspect was observed below the talar element in four patients. There were active periprosthetic ossifications in the majority of the patients.

Discussion: The insufficient ancillary for this prosthesis and its old concept explain the frequency of malleolar fractures and the level of the functional outcomes. Improved prostheses should be used. The stability of the results observed in this series of patients followed up to 12 years is an argument favouring indicating prosthesis insertion as an alternative to arthrodesis, particularly since revision of an arthrodesis is not particularly difficult, even with an iliac graft. The radiographic evidence of periprosthetic ossifications or bone resorption, particularly under the implant, emphasises the need for prolonged surveillance.

Purpose: We analysed prospectively our experience with the zincrone-polyethylene bearing for total hip arthroplasty for implantations performed between 1987 and 1997. This bearing is designed to reduce in vivo wear due to the excellent biological qualities of this ceramic.

Material and methods: Total hip arthroplasty was performed on 867 hips over the ten year period (1987–1997) in patients followed for mean seven years. All had titanium or stainless steel stems with a cemented or press fit cup (inner diameter 26-mm or 28-mm). We used Y-TZP zircone, a polycrystalline tetragonal-phase zircone stabilised by adjunction of ytterium (Prozyr). Mean patient age was 58 years (17–87). Mean body weight was 70 kg (40–125) and mean height was 167 cm (140–196). The sex-ratio was 1.3.

Results: Overall survival determined with the Kaplan-Meier method was 60% at 13 years (95%CI=55–65%). Revisions (all causes including infection) were performed on 118 hips. To our knowledge, for the entire cohort, one patient presented a zircone head fracture. Radiographic analysis showed a particular type of fracture related to isolated acetabular loosening. Comparative analysis of this type of loosening for 785 heads (26-mm) and 92 heads (28-mm) was not significant (log rank test). Taking surgical revision as the endpoint for isolated acetabular failure, implant survival at 13.5 years was 74% (95%CI=68–80), confirming the particular mode of failure with this bearing.

Discussion: This prospective analysis showed the absence of superiority of the zircone head in vivo for reduction of wear in comparison with metal heads in young subjects. The purely epidemiological data reveal formal evidence of the deleterious nature of zircone in contradiction with the expected beneficial tribiological effect. We have no physicochemical explanation for these failures. The pathology findings were non-specific, but the failure was real.

Conclusion: Considering these findings, we have abandoned use of this ceramic since 1997.

Aims: To review the early results of shoulder arthroplasty in the weight bearing shoulder of long term pareplegic patients. We have been unable to find previously published results of this subgroup of shoulder arthroplasty patients in the litterature. Method: The case notes and X-rays of 5 female patients who had undergone shoulder arthroplasty were analysed. These patients all had longstanding paraplegia and were wheelchair bound. All patients has been prospectively scored with the American Shoulder and Elbow Surgeon’s (ASES) function score and the Constant score. Results: The patients had a mean age of 70 yrs (61–88) at the time of surgery. Three of the 5 shoulders and rotator cuff tears at the time of surgery, 2 of which were repaired. The results are summarised in the table. There was no radiological evidence of failure apart from the migration of the single cemented glenoid component. Conclusion: In view of the satisfactory improvement in pain in particular following these procedures, we feel that it is reasonable to continue to offer this procedure in this subgroup of patients. We will however remain vigilant with regard to any further complications arising because of the increased loading in these prostheses at the medium and long term.

Purpose: We have used monoblock cryopreserved femoral heads for acetabular reconstruction without supporting material since 1985 for cemented total hip arthroplasty in patients with major acetabular defects. From 1985 to 1995, 140 reconstructions were performed. We present a prospective analysis of the clinical and radiological outcome at 10 years follow-up.

Material and methods: Mean age of the population was 61 years. Most of the patients had had two prior interventions. According to the SOFCOT classification, the 140 defects were: grade II 50%, grade III 35% and grade IV 15%.

The cryopreserved graft (femoral head bone bank) was used to reconstruct the acetabular defect. The graft was adapted to the size of the defect to fashion a congruent construct aimed at achieving primary stability. We did not use any supporting material in addition the primary osteosynthesis with one or two screws. A poly-ethylene cup was cemented in the graft. Most of the cement was applied onto the graft which was reamed to the size of the acetabulum. We retained a theoretical 6-year follow-up for review. All patients were seen for follow-up assessment using the Postel-Merle-d’Aubigné (PMA) clinical score and standard x-rays analysed according to the Oakeshott method. Kaplan-Meier survival curves were plotted taking change in status, revision for clinical failure as the endpoint.

Results: Mean overall follow-up was 8.5 years; it was 10 years for patients with an implant still in situ. Eight patients (5.7%) lost to follow-up were included in the series retained for analysis at mean 5-year follow-up. Thirty-five patients died during the follow-up period (25%). These patients had been followed for a mean four years before their death. Radiologically, cup tilt was not significantly altered over time. Conversely, the centre of the cup, measured from the U line, was not modified in the patients who died or in the group of living patients without revision at last follow-up. It was modified in the group of failure group: mean 28 mm postoperatively in the failure group reaching 39 mm at time of failure (ANOVA < 10-3). We had 26 failures (18%) which occurred at six years (mean); there was a peak at two years and another at nine years. Mean Kaplan-Meier survival was 13.5 years (95CI 12.5–14). The PMA clinical score improved from 3/5/3 (11) pre-operatively to 5.3/5.6/4.3 (15.2) at last follow-up.

Discussion: The overall results at 10 years in this series were globally satisfactory with a success rate above 70%. Failures were related to radiologically demonstrated graft compression with ascension of the centre of the cup measured from the U line. Comparing these results with data in the literature shows an improvement over the Harris series (7-year follow-up in a small group of 48 patients).

Conclusion: This method of acetabular reconstruction reserved for major bony defects has provided a 73% rate of success at ten years.

Purpose: We report our experience with acetabular reconstruction using cyropreserved bone bank hemipevli without a scaffold and total hip arthroplasty for major acetabular defects. Between 1985 and 1999, among 262 acetabular reconstructions requiring massive allografts using cryopre-served bone, 20 cases were performed with hemipelvi.

Material and methods: Mean age of the population was 56 years. The acetabulum had been operated on a mean three times. The 20 defects corresponded to Paprosky grade IIIB or SOFCOT grade IV bone loss. Clinical and radiological review of the 20 hips was made at a mean five years after treatment. None of the patients was lost to follow-up. The overall Postel Merle d’Aubigné (PMA) score at last follow-up was 17 for preoperatively scores at D2, M4 and S3 respectively. The acetabular defects were major and poorly described by the conventional systems. For example, the mean height of the bony defects was about 10 cm measured from the base of the radiographic U and the superolateral rim of the remaining roof.

Results: Globally, 13 patients had not required a reoperation at last follow-up. We had one postoperative death and two early displacements as well as two infections including one haematogenous infection. The Oakeschott criteria were used to analyse the review radiographs. Aseptic lysis of the graft was observed in five cases (generally around the 13th postoperative month) that required revision; a bone graft and a supporting ring were used in all cases because more bone stock was available than for the first revision. Among the 13 cases that did not require a new procedure, there were two with an ascended graft displacing the centre of rotation about 10 mm, followed by radiographic stability. The overall functional score for these 13 hemipelvi at last follow-up was 17 demonstrating the superior functional result compared with arthroplastic resection, the only alternative for such important loss of bone stock. It is not possible to implant a large non-cemented socket in these cases. Radiographic fusion was achieved, documented in 13 cases by the development of bony bridges or disappearance of the interface with oriented lines of force. Early graft resorption does not appear to occur when a metallic scaffold is associated (Garbuz).

Discussion: In all, 19 hips still had their total arthroplasty at last follow-up (one patient with failure preferred trocahntero-iliac coaptation.

Conclusion: Due to the inefficacy of alternative methods, this mode of restoration for major bone loss of the acetabular region (which facilitates secondary revision) appears to provide satisfactory results since the probability of preserving the prosthesis at a mean five years was slightly greater than 3/5. A stronger metallic scaffold may be the solution for the future.