Purpose

To assess the reliability of a biomimetic osteochondral scaffold Maioregen (Finceramica Faenza SpA, Faenza, Italt) as a salvage and joint-preserving procedure in the treatment of late stages of osteonecrosis of the knee.

Purpose

Osteochondral lesions of the knee are relatively common both in young and senior population. The very disabling clinical symptoms, in association to the scarce regenerative capacity of the articular cartilage and the increased risk of developing a secondary osteoarthritis make an effective treatment mandatory.

Introduction: The problems of the differential diagnosis (d.d.) between musculoskeletal infections and tumours are generally uncommon because both pathologies are quite rare. This is not the experience at the G. Pini Orthopaedic Institute where there are two Units specialized on bone infections and bone tumours and their clinicians often consult each other for difficult cases.

Material and Methods: On the basis of this experience, the A.A. revised clinical and radiological criteria of d.d. between acute or chronic osteomyelitis and different histotypes of musculoskeletal tumours. In particular they examined the type and the course of the symptoms, the laboratory data, the site of the lesions and the characteristics of the imaging, both for bone damages and for soft tissues invasion. Afterwards they compared this revision whit the experience of the cases consulted each other.

Results: D.d. of acute osteomyelitis include Ewing sarcoma, Osteosarcoma and Eosinofilìe granuloma, especially in children; d.d. of chronic and deep lesions (axial skeleton) in adults include lymphoma and metastasis; in the epiphysis d.d. can involve also benign lesions. This work allowed the A.A. to identify some guidelines that they consider suitable. Time, possibilities and limits of the imaging techniques like bone scans, CT and MRI are outlined, likewise time and types of direct examination of the lesions by puncture or biopsy, that was necessary in many cases, are proposed.

Conclusions: The A.A. think that these personal guidelines can help them to face easier, in the future, the difficult cases, minimizing both diagnostics and therapeutics delays and mistakes.

Introduction: In 1995 we started using, at the G. Pini Orthopaedic Istitute of Milano, a system for bone healing stimulation based on low intensity pulsed ultrasound. Advantages of the method are: home therapy (20 minutes per day); no side effects, even in the presence of metallic devices or infection; ease of use. Indications of low intensità pulsed ultrasound are bone healing after fresh frarctures, in which a significant bone healing accelation can be observed, delayed and non-unions. We share our experience in a challenging field of application: septic non-unions.

Materials and methods: We retrospectively evaluated 30 patients, treated from 1996 to 2003, affected by septic non-unions (a fracture that, in the presence of infection, did not show any significant increase in callus formation at 8 months from the time of fracture). The patients had a mean 1.7 ± 2 previous failed intervention. Patients were treated, in the absence of other medical or surgical treatment (excluding antibiotic therapy), with low intensity pulsed ultrasound (EXOGEN S.A.F.H.S. or, since year 2002, IGEA F.A.S.T.). The treatment was applied, after the necessary instructions, directly from the patient, at home, 20 minutes per day. Failures of the treatment were considered need for further surgery to stimulate bone healing, persistence of non-union at follow-up. Exclusion criteria included: evident instability of the synthesis, soft tissue loss and bone exposure, wide bone loss (> 2 cm).

Results: 24 bone healing (86 %), 4 failures (need for surgery), 2 treatment discontinuation. Mean treatment duration: 123 ± 43 days (minimum 90, maximum 240 days). No side effects local or general were observed. In 18 cases a bone debridment and/or hardware removal intervention had been performed after bone healing. At follow-up, 28 patients are free from infection, while two showed infection recurrence.

Conclusions: Low intensity pulsed ultrasound is an effective options in the treatment of septic non-unions, without side effects. An accurate indication and patient selection provide an advantageous cost/benefit ratio.

Congenital or acquired recurvatum genu might be caused by bone and/or soft tissue disorders. In bone recurvation, tibial deformity is more common; femoral deformity has clinical and X-ray features that are less important and often unidentified. We found this type of deformity in only four of 40 cases of bone recurvation.

Bone recurvation can follow a tibial or femoral fracture as well as injury with no X-ray signs. Some months later an anterior epiphysiolisis might be recognised on X-ray. This fact allows a retrospective diagnosis of fifth type Salter-Harris epiphysiolisis. Clinically a harmonious recurvatum genu would be recognised, which is difficult to distinguish from a capsulo-ligamentous disorder.

According to a subjective profile, it is featured with no objective laxity. On X-rays there are no peculiarities in the anterior view, but on the lateral view femoral condylar flattening with anterior rotation, in particular in the lateral one, can be observed. It might be useful to compare the X-ray findings to define a geometrical point termed the femoral diaphysealintercondylar angle. This has been already described and is measured between two lines, one which represents the axes of the femoral shaft, the other one the Blumensaat line; in a normal knee this angle measures 33° (±3). In knees with femoral recurvation this is higher: in our four patients the range of the angle was 45°–58°.

Procurving femoral osteotomy is the gold standard; in fact femoral closed wedge osteotomy allows a complete correction. Surgeons must avoid an overcorrection with subsequent femoral trochlear rotation and at the same time a tibial osteotomy must be avoided, which would lead to a double articular deformity, wherever it would fit with a capsulo-ligamentous recurvation.

Recurvatum genu can develop as a results of both chronic diseases “maladie des enfants alités” (Lefort), though rarely, and after trauma, which occurs more often. Surgical treatment might consist either in a de-epiphysiodesis according to Langenskield, when a bone bridge is present, or by Ilizarov technique, which allows a correction of segmentary shortening.

This kind of trauma often occurs after bone growth has ceased and this is why in our study we performed osteotomies. Femoral osteotomies are all closed wedge procedures with medial access and 90° angle blade-plate fixation. This allows early mobilisation and avoids overcorrection. Without performing this kind of procedure posteriorisation of the trochlea might occur and, consequently, over time, patellofemoral arthritis could develop. For the tibia we applied an anterior open wedge osteotomy with ATT avulsion, according to Lecuire, with which secondary low patella can be avoided. As fixation we first used screws, actually a plate to correct the co-existing valgus.

The good results of this kind of surgery justify autologus bone graft. We have not employed the the procedure described by Bowen.

Tibial and femoral deformities might cause patellofemoral problems, but they do not have to be modified every time to obtain good results. We have evaluated external tibial rotation characterised by an external tibial deformity in varus, worsening in parallel feet position. In these patients the only surgical treatment is tibial osteotomy, justified by a positive effect on the knee joint mechanics. From 1990 to 2002 we performed 25 derotation tibial osteotomies as an isolated procedure or associated with a closed wedge osteotomy. We reviewed 15 patients (16–28 years old at surgery) with special reference to pain, aesthetic criteria and functional assessments, and we reported possible negative effects of derotation (recurvation and external tibial rotation). In all the patients we found an external rotation higher than standard range and moderate varus. All patients had remission of pain; this was complete in five and partial in six. Ten patients showed an increased tibial rotation and eight of those showed even recurvation without functional sequelae. At 2–12 years of follow-up, our results are satisfactory.

The reconstruction of a skeletal defect after resection of a bone tumour represents a challenge for the orthopaedic surgeon. Age, site of the lesion and extension of the disease often limit the choice of surgical technique for a conservative procedure, but several options are available, mainly modular, composite or custom prostheses, massive bone allografts with or without autologous vascularised fibular grafts (AVF), and arthrodeses.

An interesting reconstructive technique uses the AVF graft, with microsurgical technique, alone or associated with a massive allograft. The association of a fibular transplant with an allograft increases the mechanical strength of the reconstruction, also promoting more rapid integration. The fibula is a cortical bone and it may provide mechanical strength in the reconstruction of a large segmental bony defect if employed as a viable biological rod.

In the present paper the authors discuss their experience with 17 patients treated at the Oncological Orthopaedic Unit of the G.Pini Orthopaedic Institute, for bone tumour resection and reconstruction using AVF graft, almost always combined with a bone allograft.

No treatments were performed as augmentation in osteoarticular massive allografts. Subjects’ ages ranged from 7 to 66 years (mean 25.2 years). Most of the patients were referred for a diagnosis of malignancy (15 of 17 cases) and in only two patients were the tumours not aggressive. In 11 patients the AVF was transplanted immediately after tumour resection, while in the others it was used after problems of previous reconstruction.

The authors report two cases of deep infection and four mechanical fractures (all healed after a period of cast immobilisation with or without bone bridging). All the AVF survived and healed with a good functional result for the patients except for two recurrences that required an amputation.