In this retrospective study, we re-evaluated the case histories of patients treated for diaphyseal and meta-epiphyseal fractures of the humerus by fasciculated nailing, using the Hackethal method. Our experience, beginning in 1992 through to the present, includes over 400 cases of fractures treated using this method. Among these cases, there were 250 meta-epiphyseal fractures and 200 diaphyseal fractures. Follow-up was possible in 250 cases. The number of complications encountered in the case studies considered was relatively low, including five cases of a delayed union and four cases of non-union. There were no deep or articular infections, five cases of superficial infection, four cases of fracturing of the means of synthesis, 10 cases of procidence of the wires at the level of the insertion site, and two cases of distal migration at the level of the articular cartilage of the humeral head. We did not encounter any cases of periarticular ossification or iatrogenic palsy of the radial nerve. Our methodology foresaw in all cases closed reduction of the fracture as well as epicondylar access distal to the humerus, which in some instances of multi-fragmented fractures was performed bilaterally, with the Eiffel Tower assembling method and four or five retrograde bundle wires. By using the epicondylar point of insertion, the fracture could be reduced and and torsional stability obtained, which together with the bone defect filling contributed to the primary stability of the fracture. In this retrospective study, we wanted to demonstrate the validity of the bundle nailing according to Hackethal’s method, which is distinguished by being a minimally invasive technique as well as by providing good consolidation and a low rate of complications.