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The Bone & Joint Journal
Vol. 99-B, Issue 11 | Pages 1420 - 1430
1 Nov 2017
Azboy I Barrack R Thomas AM Haddad FS Parvizi J

The number of arthroplasties being performed increases each year. Patients undergoing an arthroplasty are at risk of venous thromboembolism (VTE) and appropriate prophylaxis has been recommended. However, the optimal protocol and the best agent to minimise VTE under these circumstances are not known. Although many agents may be used, there is a difference in their efficacy and the risk of bleeding. Thus, the selection of a particular agent relies on the balance between the desire to minimise VTE and the attempt to reduce the risk of bleeding, with its undesirable, and occasionally fatal, consequences.

Acetylsalicylic acid (aspirin) is an agent for VTE prophylaxis following arthroplasty. Many studies have shown its efficacy in minimising VTE under these circumstances. It is inexpensive and well-tolerated, and its use does not require routine blood tests. It is also a ‘milder’ agent and unlikely to result in haematoma formation, which may increase both the risk of infection and the need for further surgery. Aspirin is also unlikely to result in persistent wound drainage, which has been shown to be associated with the use of agents such as low-molecular-weight heparin (LMWH) and other more aggressive agents.

The main objective of this review was to summarise the current evidence relating to the efficacy of aspirin as a VTE prophylaxis following arthroplasty, and to address some of the common questions about its use.

There is convincing evidence that, taking all factors into account, aspirin is an effective, inexpensive, and safe form of VTE following arthroplasty in patients without a major risk factor for VTE, such as previous VTE.

Cite this article: Bone Joint J 2017;99-B:1420–30.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 171 - 171
1 Jul 2002
Pimpalnerkar A Sloan R Thomas AM
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Impingement is a major part of the pathological complex of degenerative osteoarthritis of the elbow. It can be seriously disabling causing symptoms of pain, locking, swelling and reduced range of motion. Various surgical techniques, both arthroscopic as well as open, have been described which aim to remove the offending osteophytes and loose bodies in an attempt to improve elbow function.

Our study includes thirteen patients with a mean age of the 54 years (34 to 68) who underwent debridement arthroplasty of the elbow for degenerative arthritis using a modification of the Outerbridge-Kashiwagi trans-olecranon technique. This approach allows excision of posterior osteophytes, adequate clearance of the olecranon fossa,

removal of anterior coronoid osteophytes and loose bodies via a trans-olecranon fenestration and when required permits decompression of the ulnar nerve in the cubital tunnel.

At a mean follow-up of 37 months (3 to 96) the Mayo scores improved by a mean of 36 points with performance indices being rated as excellent in 5, good in 5 and fair in 3. Pain scores improved by a mean of 4 grades (2 to 8). The mean improvement in the flexion-extension arc was 28 (0 to 55). There was one complication of transient ulnar nerve neuritis, which responded to non-operative measures.

Though limited by the lack of a control group we were able to show the effectiveness and reliability of our technique in producing lasting benefit in improving range of motion and relieving pain in degenerative osteoarthritis of the elbow.