Periprosthetic infection is a serious complication after total hip arthroplasty (THA). Two stage procedure using antibiotic-impregnated cement spacer is one of the treatments for late chronic infection after THA. We investigated the effects of two stage procedure on the infection control and the recurrence of infection after revision THA. We retrospectively reviewed a consecutive series of 10 cases of a periprosthetic infection after hip arthroplasty, including 3 THA and 7 bipolar hemiarthroplasty (BHA). They were treated with two stage procedure using antibiotic-impregnated cement spacer from 2004 to 2009. There were 4 women and 6 men with an average age of 68.4 years. The pathogens were methicilin-resistant Staphylococcus aureus (MRSA) in 3 cases, coagulase-negative Staphylococcus (CNS) in 2 cases, Enterococcus in 2 cases, Streptococcus in 2 cases, and unknown in 1 case. After removal of the prosthesis, extensive debridement was performed to remove infected tissues and residual cement. After irrigation with iodine solution, antibiotic-impregnated cement spacer was inserted with proximal cement fixation to prevent dislocation and fracture of the cement spacer. The antibiotics that were impregnated in the cement spacer were VCM in 8 cases, MEPM in 1 case, and CAZ in 1 case. Intravenous antibiotics were administrated for 3 weeks after this first stage surgery, and then oral antibiotics were administrated until C-reactive protein (CRP) rates became negative. After confirming the culture of joint fluid contained no pathogens, second stage revision surgery was performed. The average follow-up period after revision THA was 2.3 years. We investigated the period from first stage surgery to the day when CRP became negative, and to the day of second stage surgery. The incidence of recurrence of infection after revision THA was investigated.Introduction
Materials and Methods
In previous congress of ISTA in Hawaii, we reported the results about accuracy of the cup center position in our image-free navigation system. In the new version of our navigation system, leg elongation and offset change as well as cup center position can be navigated. In this study, we therefore investigated the accuracy of cup center position, leg elongation and offset change. Twenty four THA operations were performed with using the image-free OrthoPilot THA3.1 dysplasia navigation system (B. Braun Aesculap, Tuttlingen, Germany) between August 2009 and December 2009 by three experienced surgeons. In this system, cup center height was shown as the distance from tear drop, and cup medialization was shown as horizontal distance from inner wall of acetabulum. Leg elongation and offset change were navigated by comparing the two reference points in femur between registration before neck resection and that after inserting the trial implant. After operation, the cup angles were measured on CT image, and cup center position, leg elongation and offset change were measured on plain radiography. We compared these values that indicated by the navigation system to those measured on the CT image and the plain radiography. The average cup inclination was 37.5 ± 7.0 degree and anteversion was 22.2 ± 4.7 degree. The average absolute difference between navigation and measured angles were 5.2 ± 4.0 degree in inclination, 5.9 ± 4.0 degree in anteversion. The difference of cup height was 5.8 ± 3.9 mm, cup medialization was 3.8 ± 2.7 mm, leg elongation was 4.3±3.3mm, and offset was 5.4±4.1mm, respectively. By using this new version navigation system, we can plan the cup center position and navigate it within smaller error of vertical and horizontal direction than the previous system. Moreover, leg elongation and offset change can be satisfactory navigated during operation. However surgeon's skill and learning curve might have influence the accuracy. We have to continue to evaluate this system and make effort to further improvement.
Nowadays navigation system for THA is widespread and contributes to accurate cup installation as for cup abduction and anteversion angles. On the other hand, cup center position is very important to prevent leg length discrepancy and to acquire appropriate muscle tension especially for DDH cases. However planning and accuracy of cup center position was rarely mentioned when the efficacy of navigation systems were discussed. We therefore examined not only accuracy of cup angles, but also of cup center position in our image-free navigation system for DDH. One hundred three THA operations were performed with using the image-free OrthoPilot hip navigation system (B. Braun Aesculap, Tuttlingen, Germany) between May 2006 and July 2008 by three experienced surgeons. In this system, we can measure the length between two different points marked by special pointer during surgery. Thus we pointed the upper rim of obturator foramen (this mark was estimated the lower tip of tear drop, and the bottom of reaming hole (this mark was estimated same height from cup center position) before cup installation and measured the vertical length between them(op length). After operation, we measured the vertical length from tear drop to cup center on the x-ray film (xp length), and compared these two values. The average difference of two values were 6.41±4.17 mm ((op length)-(xp length)). Secondly we divided them into two groups, large error group (>
0.7mm) and small error group (<
0.6mm) and investigated the cause of large error. As result, large error was influenced by difference of surgeons, whereas not influenced by patient’s etiology and BMI. By using image-free navigation system for DDH, we can plan the cup center position and install it within the error of 6.4mm. This will contribute to avoid a lot of hesitations during surgery. However surgeon’s skill and habitants have influence on this technique. We have to investigate this system and make effort to further improvement continuously.
Direct anterior approach (DAA) is an inter-muscular approach that needs no muscle detached. In THA through DAA approach, exposure of the acetabulum is facilitated, while the key points of this approach are femoral lift-up and hip extension to get sufficient access to the femoral canal. To investigate the strategy for femoral lift-up, we released the capsule step by step and measured the distance of femoral lift-up at each step in cadavers and clinical cases. The effects of hip extension on femoral lift-up were also evaluated. Three fresh frozen cadavers were used. In supine position, the hip joint was exposed through DAA by two experienced surgeons. After anterior capsulotomy and femoral head resection, posterior capsule release was performed followed by superior capsule release in one side, and superior release was followed by posterior release in the other side. Finally, internal obturator muscle was released in both side. At each step, the distance of femoral lift-up was measured under the traction force of 70N. The effects of hip extension were investigated in 0, 15 and 25 degrees hyper-extension. Thirty-six THA were performed through DAA. Posterior capsule release was performed followed by superior capsule release in 13 hips, and superior release was followed by posterior release in 23 hips. At each step, the distance of femoral lift-up was measured under the traction force of 70N at each step same as the cadaver study. In cadaver study, anterior capsulotomy and posterior capsule release affected little the femoral lift-up. The distance increased after superior capsular release. The distance decreased as hip hyperextension unless the superior capsule was released. The effect of internal obturator muscle release was not observed. In clinical studies, the same tendency was observed in clinical cases. Superior capsule release was the most effective for the femoral lift-up. The results of this study indicate that superior capsule release is the first step for the femoral liftup. The second step is hip extension to get access to the femoral canal. By performing these procedures step by step, rasping and stem insertion can be achieved with minimal soft tissue release.
In image-free navigation system, three bony landmarks (typically both anterior superior iliac spines (ASIS) and pubic symphysis) are registered intraoperatively by manual palpation. If the registration of bony landmarks is inaccurate, the final orientation of the cup determined by the navigation system will also be inaccurate. We therefore examined intra-and intersurgeon variability in registration and the distance between registration points in each bony landmark with two surgical positions. Thirty-seven THAs were performed in the lateral position and 15 THAs were performed in the supine position. The cup was fixed using the image-free Ortho-Pilot hip navigation system (B. Braun Aesculap, Tuttlingen, Germany). The registration was repeated two more times by operator and assistant, and the intra-and intersurgeon variability of cup abduction angle and anteversion was analyzed by ICC (intraclass correlation coefficients). In 25 hips, the distance between intrasurgeon registration points and that between intersurgeon registration points in each landmark were calculated. The ICC in the lateral position ranged between 0.59 and 0.81, and between 0.85 and 0.95 in the supine position. The ICCs of cup abduction angle for the intra-and intersurgeon variability were 0.92 and 0.95 for the supine position and 0.65 and 0.59 for the lateral position. Those of anteversion were 0.93, 0.85, and 0.81, 0.72, respectively. The variability of registration of collateral and contralateral ASIS in the lateral position was greater than that in the supine position. In image-free navigation system, the variability of registration points depended on bony landmarks and patient position. The registrations of pubic symphysis in the supine position and all bony landmarks in the lateral decubitus position are standing further improvement.
Pelvic inclination angle (PIA) and lumbar lordotic angle (LLA) were measured on the standing lateral X-rays before operation and 1-month, 6-month and 1-year post-operation. The effects of patient age, BMI, ROM of the hip, preoperative PIA and LLA on the changes of PIA were statistically investigated using multiple linear regression analysis. We divided the patients into three groups with regard to pre-operative PIA (anterior group: PIA <
0, intermediate group: 0 <
PIA <
10, posterior group: PIA >
10) and with regard to pre-operative LLA (insufficient group: LLA <
20, moderate group: 20 <
LLA <
40, severe group: LLA >
40).