Canada is second only to the United States worldwide in the number of opioid prescriptions per capita. Despite this, little is known about prescription patterns for patients undergoing total joint arthroplasty (TJA). The purpose of this study was to detail preoperative opioid use patterns and investigate the effect it has on perioperative quality outcomes in patients undergoing elective total hip and total knee arthroplasty surgery (THA and TKA).

The study cohort was constructed from hospital Discharge Abstract Data (DAD) and National Ambulatory Care Reporting System (NACRS) data, using Canadian Classification of Health Intervention codes to select all primary THA and TKA procedures from 2017-2020 in Nova Scotia. Opioid use was defined as any prescription filled at discharge as identified in the Nova Scotia Drug Information System (DIS). Emergency Department (ED) and Family Doctor (FD) visits for pain were ascertained from Physician Claims data. Multivariate logistic regression was used to test for associations controlling for confounders. Chi-squared statistics at 95% confidence level used to test for statistical significance.

In total, 14,819 TJA patients were analysed and 4306 patients (29.0%) had at least one opioid prescription in the year prior to surgery. Overall, there was no significant difference noted in preoperative opiate use between patients undergoing TKA vs THA (28.8% vs 29.4%). During the period 2017-2019 we observed a declining year-on-year trend in preoperative opiate use. Interestingly, this trend failed to continue into 2020, where preoperative opiate use was observed to increase by 15% and exceeded 2017 levels. Within the first 90 days of discharge, 22.9% of TKA and 20.9% of THA patients presented to the ED or their FD with pain related issues. Preoperative opiate use was found to be a statistically significant predictor for these presentations (TKA: odds ratio [OR], 1.45; 95% confidence interval [CI], 1.29 to 1.62; THA: OR, 1.46; 95% CI, 1.28 to 1.65).

Preoperative opioid consumption in TJA remains high, and is independently associated with a higher risk of 90 day return to the FD or ED. The widespread dissemination of opioid reduction strategies introduced during the middle of the last decade may have reduced preoperative opiate utilisation. Access barriers and practice changes due to the COVID-19 pandemic may now have annulled this effect.

The coronavirus pandemic has reduced the capability of Canadian hospitals to offer elective orthopaedic surgery requiring admission, despite ongoing and increasing demands for elective total hip and total knee arthroplasty surgery (THA and TKA). We sought to determine if the coronavirus pandemic resulted in more outpatient THA and TKA in Nova Scotia, and if so, what effect increased outpatient surgery had on 90 day post-operative readmission or Emergency Department/Family Doctor (FD) visits.

The study cohort was constructed from hospital Discharge Abstract Data (DAD), inpatient admissions, and National Ambulatory Care Reporting System (NACRS) data, day surgery observations, using Canadian Classification of Health Intervention codes to select all primary hip and knee procedures from 2005-2020 in Nova Scotia. Emergency Department and General Practitioner visits were identified from the Physician Billings data and re-admissions from the DAD and NACRS. Rates were calculated by dividing the number of cases with any visit within 90 days after discharge. Chi-squared statistics at 95% confidence level used to test for statistical significance. Knee and hip procedures were modelled separately.

There was a reduction in THA and TKA surgery in Nova Scotia during the coronavirus pandemic in 2020. Outpatient arthroplasty surgery in Nova Scotia in the years prior to 2020 were relatively stable. However, in 2020 there was a significant increase in the proportion and absolute number of outpatient THA and TKA. The proportion of THA increased from 1% in 2019 to 14% in 2020, while the proportion of TKA increased from 1% in 2019 to 11% in 2020. The absolute number of outpatient THA increased from 16 cases in 2019, to 163 cases in 2020. Outpatient TKA cases increased from 21 in 2019, to 173 in 2020. The increase in outpatient surgery resulted in an increase in 90 day presentations to ED following TKA but not THA which was not statistically significant. For outpatient THA and TKA, there was a decrease in 90 day readmissions, and a statistically significant decrease in FD presentations.

Outpatient THA and TKA increased significantly in 2020, likely due to the restrictions imposed during the coronavirus pandemic on elective Orthopaedic surgery requiring admission to hospital. The increase in outpatient surgery resulted in an increase in 90 day presentations to ED for TKA, and a decrease in 90 day readmissions and FD presentations for THA and TKA. Reducing the inpatient surgical burden may result in a post-operative burden on ED, but does not appear to have caused an increase in hospital readmission rates.

Recent analysis of the Australian Joint Replacement Registry revealed the rate of revision of primary total hip arthroplasty was greater with cement-less fixation than with cemented fixation. The seven-year results of the New Zealand Joint Registry have also shown an increased revision rate with cement-less hip arthroplasty. The purpose of this study was to review the revision rate of cemented and cement-less total hip arthroplasty from those joint replacements registered with the New Zealand Joint Registry and to determine the cause for revision.

All 42 1000 primary total hip arthroplasties recorded in the New Zealand National Joint Registry since its establishment in 1999, until December 2006, were included in the study. The rate of revision of cemented and cement-less femoral and acetabular components was calculated for the study period, and for the first 90 days after the operation. The reasons for revision were evaluated and compared for different methods of fixation. Survival curves were constructed for each combination of femoral and acetabular component fixation.

Two hundred and eighty three cement-less (2.46%), 294 cemented (1.91%), and 321 cemented femoral with cement-less acetabular fixation (2.19%) primary total hip arthroplasties have been revised. The difference in revision rate between each group was statistically significant. There were only 573 primary total hip arthroplasties performed with cement-less femoral and cemented acetabular component, with 11 revised. The rate of revision was highest in the cement-less group (0.74% revised per year), and lowest in the cemented group (0.47%).

The predominant reason for revision in all three major groups was dislocation. Revision for loosening of the acetabulum was more common with cemented fixation. Revision for fractured femur was more common with cement-less fixation, and revision for deep infection was most common in the cemented group. These differences were all shown to be statistically significant. Revision for loosening of the femoral component and pain was more common in the cement-less group, but was not shown to be statistically significant.

In the first 90 days, there were a large number of revisions in the cement-less group (0.77%), compared to the cemented group (0.32%), and cemented femur with cement-less acetabulum group (0.57%). Dislocation was again the most common reason for revision. Revision for fractured femur was high in the cement-less group (0.19%) in the first 90 days. Excluding these early revisions, the number of revisions in the cemented and cement-less groups maintained a similar rate for the remainder of the study period.

This study confirmed that the revision rate for uncemented THA was higher than for cemented THA. The major difference was the early revision rate within 90 days. Addressing these problems would improve the overall early outcome.