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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_14 | Pages 66 - 66
1 Dec 2019
Berberich C Sanz-Ruiz P
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Aim

There is an ongoing controversy whether the observed benefit of infection risk reduction by ALBC outweighs the risk of possible antimicrobial resistance development.

Methods

The scientific & clinical literature in PubMed, Medline and Embase has been systematically reviewed with the keywords “antibiotic resistance”, “antibiotic loaded bone cement”, “local antibiotics”, “bacterial colonization” and “joint infection”. In total 28 relevant publications were found with the majority of them reporting laboratory results. Only 7 papers focused on clinical septic situations & patient data