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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_4 | Pages 129 - 129
1 Feb 2017
Lyons S Leary J Broach W Shaw L Santoni B Bernasek T
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Background

Periprosthetic joint infection (PJI) is a devastating complication and interest exists in finding lower cost alternatives to current management strategies. Current strategies include a two-stage revision with placement of an antibiotic spacer and delayed placement of a new arthroplasty implant. This study aimed to show that biofilm residue can be reliably eradicated on infected implants, safely allowing re-implantation in a spacer.

Methods

Strains of Staphylococcus aureus MRSA252 or Staphylococcus epidermidis RP62A were grown on cobalt-chrome discs. For each strain, discs were divided into 5 groups (5 discs each) and exposed to several sterilization and biofilm eradication treatments: (1) autoclave, (2) autoclave + sonication; (3) autoclave + saline scrub; (4) autoclave + 4% chlorhexidine (CHC) scrub; and (5) autoclave + sonication + CHC scrub. Sterilization and biofilm eradication were quantified with crystal violet assays and scanning electron microscopy (SEM).


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 172 - 172
1 Dec 2013
Simon P Diaz M Schwartz D Santoni B Frankle M
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Introduction:

The complex 3D geometry of the scapula and the variability among individuals makes it difficult to precisely quantify its morphometric features. Recently, the scapular neck has been recognized as an important morphometric parameter particularly due to the role it plays in scapular notching, which occurs when the humeral component of a reverse shoulder arthroplasty (RSA) prosthesis engages the posterior column of the scapula causing mechanical impingement and osseous wear. Prosthetic design and positioning of the glenoid component have been accepted as two major factors associated with the onset of notching in the RSA patient population. The present image-based study aimed to develop an objective 3D approach of measuring scapular neck, which when measured pre-operatively, may identify individuals at risk for notching.

Materials and Methods:

A group of 81 subjects (41 M, 69.7 ± 8.9 yrs.; 40 F, 70.9 ± 8.1 yrs.) treated with RSA were evaluated in this study. The 3D point-cloud of the scapular geometry was obtained from pre-operative computed tomography (CT) scans and rendered in Mimics. Subsequently, a subject-specific glenoid coordinate system was established, using the extracted glenoid surface of each scapula as a coordinate reference. The principal component analysis approach was used to establish three orthogonal coordinate axes in the geometric center of the glenoid. Utilization of glenoid-specific reference planes (glenoid, major axis, and minor axis plane) were selected in order to remove subjectivity in assessing “true” anterior/posterior and profile views of the scapula. The scapular neck length was defined as the orthogonal distance between the glenoid surface and the point on the posterior column with the significant change of curvature (Fig. 1). In addition, the angle between the glenoid plane, area center of the glenoid, and the point of significant change of the curvature were assessed (Fig. 2). This new parameter was developed to serve as a predictive critical value for the occurrence of notching. The incidence of notching increases as the value of the notching angle decreases. In order to evaluate relationships between glenoid and scapular neck, the glenoid width and height was also measured at the glenoid plane.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 22 - 22
1 Dec 2013
Frankle M Cabezas A Gutierrez S Teusink M Santoni B Schwartz D
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Background:

Currently, there are a variety of different reverse shoulder implant designs but few anatomic studies to support the optimal selection of prosthetic size. This study analyzed the glenohumeral relationships of patients who underwent reverse shoulder arthroplasty (RSA).

Methods:

Ninety-two shoulders of patients undergoing primary RSA for a massive rotator cuff tear without bony deformity or deficiency and 10 shoulders of healthy volunteers (controls) were evaluated using three-dimensional CT reconstructions and computer aided design (CAD) software. Anatomic landmarks were used to define scapular and humeral planes in addition to articular centers. After aligning the humeral center of rotation with the glenoid center, multiple glenohumeral relationships were measured and evaluated for linearity and size stratification. The correction required to transform the shoulder from its existing state (CT scan) to a realigned image (CAD model) was compared between the RSA and control groups. Size stratification was verified for statistical significance between groups. Generalized linear modeling was used to investigate if glenoid height, coronal humeral head diameter and gender were predictive of greater tuberosity positions.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 427 - 427
1 Dec 2013
Mighell M Miles J Santoni B Anijar L James C
Full Access

Purpose:

Tuberosity healing in hemiarthroplasty for proximal humerus fractures remains problematic. Improved implant design and better techniques for tuberosity fixation have not been met with improved clinical results. The etiology for tuberosity failure is multifactorial; however thermal injury to host bone is a known effect of using polymethylmethacrylate for implant fixation. We hypothesized that the effect of thermal injury at the tuberosity shaft junction could be diminished by utilizing an impaction grafting technique for hemiarthroplasty stems.

Methods:

Five matched pairs of cadaveric humeri were skeletonized and hemiarthroplasty stems were implanted in the proximal humeri in two groups. The first group had full cementation utilized from the surgical neck to 2 cm distal to the stem (cement group) and the second group had distal cementation with autologous cancellous bone graft impacted in the proximal 2.5 cm of the stem (impaction grafting group). Thermocouples were used to measure the inner cortical temperature at the tip of the stem, surgical neck, and at the level of the cement-graft interface for both treatment groups (see Fig. 1). Experiments were initiated with the humeri fully submerged in 0.9% sodium chloride and all three thermocouples registering a temperature of 37 ± 1°C. Statistical analyses were performed with a one-sided, paired t-test.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 536 - 536
1 Dec 2013
Simon P Virani N Diaz M Teusink M Santoni B Frankle M
Full Access

Introduction:

Subchondral bone density (SBD) distribution is an important parameter regarding that may be important when considering implant stability. This parameter is a reflection of the loading experienced by the joint throughout the lifetime and may be useful in pre-surgical planning and implant design. Clinically, the question of the glenoid surface preparation for TSA/RSA remains controversial, despite numerous published studies on glenoid bone morphology. To address this question, there exists a need to develop a 3D quantitative method capable of analyzing the complex glenoid bone morphology at different depths from the surface. Computed tomographic osteoabsoptiomery (CT-OAM) evaluates SBD based on the Housfield Unit (HU) value of each pixel. In this pilot study, we aimed to analyze SBD distribution of the glenoid at different depths by means of CT-OAM in male TSA subjects.

Materials and Methods:

A study group of twenty male TSA patients (61–69y.o) were included in this study. Each subject obtained a pre-operative CT scan following a standardized protocol on the same CT scanner (1.25 mm slice thickness). Resultant DICOM 2D images were processed in custom-written program (VC++) and the surface of every glenoid was manually traced from the axial slices. Care was taken during the manual tracing process to exclude osteophytes and cyst formations from the resultant surface. Values of HU at every selected pixel on the surface of the glenoid were recorded. Subsequently, the layer of pixels at a 0.5 mm distance from the previous surface was virtually scraped and the HU values of new layer of pixels were recorded. This routine was repeated up to a depth of 5 mm from the glenoid surface, taking measurements on 11 virtual 3D surfaces with a thickness of 0.5 mm. Mean SBD distribution was reported for each layer and differences were compared using ANOVA and Fisher's post-hoc test.