Background

The diagnosis of periprosthetic joint infection (PJI) remains a challenge in clinical practice and the analysis of synovial fluid (SF) is a useful diagnostic tool. Recently, two synovial biomarkers (leukocyte esterase (LE) strip test, alpha-defensin (AD)) have been introduced into the MSIS (MusculoSkeletal Infection Society) algorithm for the diagnosis of PJI. AD, although promising with high sensitivity and specificity, remains expensive. Calprotectin is another protein released upon activation of articular neutrophils. The determination of calprotectin and joint CRP is feasible in a routine laboratory practice with low cost.

Background

The objective was to evaluate the benefit that could be obtained in terms of pain and efficacy with processed segmental allografts on 20 patients in meniscal repair treatment.

Introduction: Lateral meniscectomies lead to degenerative arthritis and therefore meniscus transplantation has been considered. In literature, this procedure appears to have good clinical results. The aim of this study was to evaluate our clinical results at mid-term follow-up and to correlate these results to the morphology and position of the transplanted meniscus.

Material and methods: Twenty-eight patients operated in 4 surgical centers, were retrospectively reviewed following lateral meniscal allograft transplantation. The mean age of the patients was 34 years (range, 18 to 50 years). Before surgery, all these patients suffered of permanent lateral femorotibial pain without radiological knee arthritis. The knees were all stable or stabilized, without axial malalignment of the lower limbs or corrected by a concomitant high tibial osteotomy. Arthroscopic procedure was performed for 9 patients and arthrotomy for 19 patients. Different techniques of fixation of the transplant were used, with or without bone plugs. The associated procedures were 2 ACL reconstruction, 3 high tibial varus osteotomies, and 1 mosaicplasty. The IKDC score were used for the analysis of the functional results. An arthroTDM or an arthro MRI was used to analyse the morphology and position of the transplanted meniscus.

Results: The mean follow-up was 35 months (range, 12 months to 6 years). The mean post-operative subjective IKDC score was 65.5 points (range, 19.5 to 89 points). There were 2 failures associated with a fast arthritic evolution and 2 functional bad results. The others 24 patients (85%) were satisfied or very satisfied, with a real improvement of the pain and the function. Seventeen patients (60%) have started again a sportive activity superior than the one pre-operating. At the last follow-up, all transplanted meniscus have healed, but the morphology and position of the transplanted meniscus was not always normal with absence of the middle segment in 3 cases; its extrusion in 9 cases, a posterior segment shortened or partially hurt in 5 cases and its absence in 3 cases. Better results were associated with good meniscus positioning and morphology.

Discussion: Our works confirm that lateral meniscal allograft is a therapeutic option with favourable results in terms of pain reduction and functional improvement in the medium term for symptomatic patients after lateral meniscectomy. Our results are comparable with those of the literature. The allograft is technically reliable, reproducible notably for the methods of fixation. A long term follow-up is necessary to evaluate the benefit of these grafts on the protection of the cartilage.

Purpose: To review the results of periprosthetic femoral fractures treated using cortical strut allograft and plate internal fixation.

Material & Methods: Between November 1996 and July 2006, 17 patients with periprosthetic fractures of the femur after hip arthroplasty were treated using deep-frozen cortical strut allografts as an adjunct support after internal fixation. The average age was 79 years (range 56 to 96 years) with 13 woman and 4 men. According to the Vancouver classification system, there were 6 type B1, 5 type B2, 1 type B3 and 5 type C fractures. All fractures were closed except for one type I of Gustilo. Twelve patients had internal fixation of the fracture using a Dall-Miles cable and plate system, 5 using a AO/ASIF 4.5 dynamic compression plate, and 2 had an associated revision arthroplasty of the stem. Cortical strut allograft was used from the femur in 6 cases and from the tibia in 11 cases. Mean follow-up was of 97.5 weeks.

Results: One patient presented a rupture of a screw and varus displacement of the fracture, but healed without symptomatic complaints. A superficial infection occurred in the patient with open fracture. All the patients, except for two, required allogenic blood transfusion. Mean inhospital stay was of 18.6 days and walk with weigh was allowed at a mean of 50.9 days. Two patients died few weeks after the treatment due to complications of their previous pathological disorders. Aseptic loosening of a hip arthroplasty occurred at two years follow-up requiring revision surgery. Three patients referred mild pain at the last follow-up visit.

Conclusions: Cortical strut allograft associated with internal fixation has provided satisfactory results in the present serie. We consider this procedure safe and effective, specially for type B1 and C periprosthetic femoral fractures.

Purpose of the study: Spontaneous repair of lost deep chondral tissue is minimal in the knee joint. A clinical trial of chondrocyte autografts as described by Brittberg and Peterson was undertaken by the Nantes University Hospital and the French Society of Arthroscopy in 1999.

Material and methods: Twenty-eight patients, mean age 28 years, underwent surgery in eight centers. Etiologies were: osteochondritis (n=14), isolated posttraumatic chondorpathy (n=7), chondropathy and full-thickness ACL tear (n=7). All lesions involved the condyles and were deep (ICRS grades 3 and 4). Mean surface area involved after debridement was 490 mm2 (range 150–1000 mm2). Patients were followed three years after the autologous grafting to assess functional outcome. An MRI was obtained at 2–3 years. Thirteen control arthroscopy procedures were performed including eight with biopsy specimens for histology and immunohisto-chemistry studies.

Results: Twenty-six patients were reviewed at more than two years. There were no general complications, three patients presented a partial avulsion of the graft treated by arthroscopy and one underwent arthrolysis at six months. Function improved in all patients except three and pain improved in all. The ICRS score improved from 43 points (range 19–70) to 77 points (range 39–84). Sixteen control MRIs were available and showed that the graft was hypertrophic in eleven cases, on level in four, and insufficient in one. Marginal integration was good in 11 cases and partial in five. Subchondral integration was complete in ten cases and mediocre in six. The arthroscopic score was nearly normal (score 8–11) in eight cases and abnormal in five (score 4–7). The histological class according to Knutsen (hyaline richness) was: one in group 1 (> 60%), three in group 2 (> 40%), four in group 3 (< 40%) and one in group 4 (bony or fibrous tissue). Function score (r=0.78 and MRI score (r=0.76) were correlated with arthroscopic sores. There was no correlation with the histological results.

Discussion: Clinical outcome was improved in more than 80% of cases, similar to results reported for histological series. The arthroscopic and histological results were equivalent to those reported by Knutsen but inferior to those reported by Bentley or Peterson.

Introduction: Treatment and outcome of patients with rheumatoid arthritis and distal humerus fractures is not well established.

Methods: Between 1982 and 2002 twenty-four elbows in twenty-two patients (eleven men, eleven women) treated for acute distal humerus fractures were retrospectively reviewed. The average age at time of the fracture was 64 years. Eleven elbows were immediately treated with a total elbow arthroplasty (TEA) type Coonrad-Morrey (CM), six elbows had underwent open reduction and internal fixation (ORIF), and seven elbows were referred to our institution after failed ORIF elsewhere and were revised with an TEA (CM).

Results: At an average follow-up of 52 months the Mayo Elbow Performance Score (MEPS) averaged in the eleven elbows with an immediate TEA 96 points and in the six elbows with ORIF 93 points (p=0.79). In the seven elbows with TEA after failed ORIF there was a trend towards a less favorable outcome (MEPS: 86 points) but the differences was not significant compared to immediate TEA (p=0.31) and ORIF (p=0.53). Patients with failed ORIF and a subsequent TEA had an average of 3 operation per elbow with one patient ending in elbow resection after an infected TEA. Patients with immediate TEA had an average of 1.3 operations and patients with successful ORIF 1.2 interventions.

Discussion and Conclusion: Distal humerus fractures in patients with rheumatoid arthritis can be treated successfully with an immediate TEA or ORIF. There is a trend towards a poorer clinical outcome in patients with TEA after failed ORIF.

Objective: Retrospective analysis of consecutive paediatric patients treated surgically for high-grade spondylolisthesis by one of three circumferential surgical procedures with emphasis on complications and patient outcome measurements.

Methods: Between 1980 and 1998 fourty patients underwent anterior-posterior correction for Meyerding Grade 3 or 4 isthmic dysplastic spondylolisthesis. Ten patients were treated with an anterior reduction according to Louis and anterior interbody fusion followed by posterior decompression and instrumented fusion (group A). Fourteen patients underwent posterior decompression followed by anterior reposition and fusion with tricortical iliac bone crest and posterior instrumented fusion (group B). Sixteen patients underwent progressive reduction by halopelvic traction followed by anterior and posterior fusion (group C). All patients completed the North American Spine Society (NASS) outcome questionnaire and the SF-36. The cosmetic assessment was performed by means of a VAS. The mean follow-up period for group A was 13,5 years, for group B 5,5 years and for group C 15,4 years, respectively.

Results: The three groups were comparable with respect to age at operation, radiographic measurement of the slip, lumbosacral kyphosis and lumbar lordosis. The incidence of postoperative extensor hallucis longus weakness was 33% in group A, 50% in group C and 0% in group B (p< 0.001). Pearson correlation coefficient revealed a positive correlation between extensor hallucis longus weakness and the degree of correction of the lumbosacral kyphosis (P=0.56, p=0.024). Postoperative reduction of the sagittal slip (A: 64%, B: 44%, C: 50%) and lumbosacral kyphosis (A: 27°, B: 16°, C: 27°) was significant in all three groups. The incidence of pseudarthrosis was 10% in group A, 7% in group B and 6% in group C. SF-36 and NASS outcome questionnaire results have not been found statistically significant among the groups.

Conclusion: Outcomes of function, satisfaction and cosmesis are satisfactory in all three surgical groups. Posterior decompression followed by anterior reduction and fusion using tricortical iliac crest bone graft and posterior instrumented fusion lack neurogenic complications. Therefore it is the standard surgical procedure for severe isthmic dysplastic spondylolisthesis at our department.

Purpose: The purpose of this retrospective study was to detail factors influencing outcome of corticocancellous grafts for the treatment of scaphocarpal non-union and to determine ideal indications.

Material and methods: Between 1984 and 1999, this grafting technique was used for 103 patients; we retained for analysis 57 wrists (58 nonunions). Mean follow-up was 106 months. Mean age was 36 years. For 45 patients, non-union occurred because of misdiagnosis. According to the Schernberg classification, eleven nonunions were in zone II, 40 in zone III, and seven in zone IV. Time from fracture to treatment was 35 months on average. The Alno classification of non-union was: stage I=13, stage IIA=20, stage IIA=22, stage IIIA=2, stage IIIB=1. The graft was harvested from the pelvis in 50 cases. Osteosynthesis was associated with a graft in 33 of the 58 cases. Postoperative immobilisation was maintained for 2.7 months on average. Bone healing was achieved within thee months.

Results: Thirty-six patients were very satisfied. Twenty-seven had significant pain on the pelvic harvesting site (50 harvestings). Wrist motion was 56.2° flexion, 56° extension, 83° supination, 83° pronation, and 11° radial and 32.7° ulnar inclination. Thumb opposition was noted 9.4/10 and average contraopposition was 4. Mean index of carpal height was 0.547. The mean radiolunate angle was 4.8°. A DISI deformation was observed for 20 wrists. Thirty-six patients (62%) developed little or no osteoarthritis. The rate of bone healing was 81% but eleven nonunions did not heal, including seven cases of necrosis of the proximal pole. The absence of DISI deformation correction at the time of grafting favoured development of radiocarpal osteoarthritis. The presence of necrosis favoured persistent non-union. Concomitant osteosynthesis did not improve the healing rate.

Discussion: Treatment of scaphoid non-union with a corticocancellous graft remains the choice alternative, providing 81% healing. Grafts consolidation must occur at the radial epiphysis in order to limit painful sequelae. This procedure can be performed for patients with a DISI deformation, but vascularised grafts should be preferred in the event of necrosis of the proximal pole of the scaphoid.

Purpose: The few reports of long-term outcome of Kien-böck disease are helpful in establishing therapeutic indications.

Material and methods: Between 1970 and 1995, radius shortening procedures were performed in 44 patients. Among these 31 patients (eight women and 23 men), mean age 32 years (18–48) at surgery, with 33 operated wrists (18 right, 11 left, 2 bilateral, 19 dominant hands) were reviewed clinically (25 patients by an independent observer, three by their family physician) and radiologically (26 patients) or responded to a phone interview (five patients) at a mean 12 years follow-up (4–19 years). Four patients had died, nine were lost to follow-up. Before surgery the pain was intense (Michon scale): 32 grade I, one grade II. According to Lichtman, there were three grade I, seven grade II, eighteen grade IIIa and five grade IIIb. There was one case of haematoma and one reflex dystrophy, five late consolidations and five nonunions (three diaphyseal out of eight and two metaphyseal out of 25).

Results: The Michon pain score was variable, 11 grade IV, six grade III, nine grade II, but also seven grade I and four secondary arthrodeses. Postoperative amplitudes ere: flexion 50°, extension 53°, abduction 20°, adduction 29°, pronation 83°, supination 74°. Mean amplitudes increased for flexion (+12°), extension (+13°), abduction (+6°), and adduction (+11°), but decreased for pronation (−3°) and supination (−13°). The postoperative wrist fore (Jamar) was 32 kg (80° of other side). Eighteen patients were able to resume an occupational activity, requiring equivalent (14 patients, including 12 manual labourers) or greater (two patients) wrist force. At last follow-up the Lichtman classification was one grade I, four grade II, eight grade III1, three grade IIIb, and seven grade IV. The pre- to postoperative radiography comparison (26 wrists) showed two improvements, seven stabilisations, 14 aggravations, and three arthrodeses. There were also three cases of ulnocarpal impingement (one reoperated). Discussion: the factors predictive of good outcome were minimally advanced disease (Lichtman), little reduction in lunatum height (Stahl), absence of carpal collapse (McMurtry), absence of complication.

Conclusion: Shortening of the radius is an excellent procedure to Lichtman grade IIIa. Results are less satisfactory for grade IIIb but still acceptable compared with resections of the first row or intracarpal arthrodesis. To avoid the risk of ulnocarpal impingement, it would be preferable to reorient the glenoid or shorten the capitatum rather than shorten the radius in patients with a normal radioulnar index.

Purpose of the study: Equinus in patients with cerebral palsy results from at least two factors: excessive contracture of the triceps surae and muscle retraction. Tendon surgery and progressive lengthening techniques using plaster walking boots can provide variable improvement in retraction. We compared the effect of this technique when applied with or without prior 40°C warming in the same patients. We also assessed the efficacy of this treatment method in terms or degree of retraction, patient age, puberty maturity, and sex.

Materials and methods: This series included 70 muscles in 52 patients with cerebral palsy aged 2 years 11 months to 21 years (mean 8 years 3 months). Common features in these patients were: equinus mainly explained by triceps retraction, no history of prior surgery on the triceps tendon, knee flexion less than 15° in the upright position, easily reduced lateral deformation of the foot, absence of mediotarsal dislocation, triceps stretching could be achieved without triggering unacceptably intense contracture.

The retraction of the triceps surae was measured from the maximal passive dorsal flexion angle of the foot, before and after applying each stretching boot. The difference between these measurements gave the gain obtained with the plaster boot. Protocol R− (stretching with plaster boot) consisted in a series of slow stretchings for 10 minutes before making the boot which was worn 7 days. Recurrent retraction in these same patients warranted another treatment within a delay of 3 to 17 months (mean delay 8.7 months). The same treatment then followed protocol R+ where the stretching was preceded by immersion of the segment in a 40°C water bath for 10 minutes.

Results: Mean gain obtained with protocol R+ (warming) was 6.8° knee extended and 7.1° knee flexed. These differences were highly significant in both cases (p < 0.0001). We had no failures with protocol R+ while with protocol R− (stretching without warming) the gain was nil or less than 5° for 29 muscles knee extended and for 32 muscles, knee flexed. The gain was not related to age, sex or puberty maturity. It was not related to the angle of dorsal flexion of the foot prior to stretching.

Discussion: Our findings demonstrate that when the conditions allowing prolonged stretching of the triceps surae are present, prior warming at 40°C for 10 minutes leads to an improvement in muscle lengthening in all patients, even in those for whom prior treatment had been unsuccessful without warming. This observation would indicate that the mechanisms allowing greater lengthening are present in all patients with cerebral palsy but that they cannot be triggered due to abnormal muscle viscosity related to distal vasomotor disorders frequently observed in this condition. Further research is needed to detail this point.

Purpose: The synovectomy-reaxation-stabilisation (SRS) procedure classically involves tenosynovectomy of the extensors, articulr synovectomy, partial deinnervation of the wrist, and tendon transfer. The purpose of this study was to: 1) evaluate functional and radiographic results, 2) search for possible correlations between results and the extent of articular synovectomy or type of tendon transfer.

Material and methods: Between 1984 and 1998, an SRS procedure was performed in 75 patients, 14 were excluded: seven had died, five were lost to folow-u and two had had wrist arthrodesis. A total of 73 wrists were analysed in 61 patients. Mean follow-up was 70 months and mean patient age was 53 years. Functional assessment was based on the Gschwend pain scale.

Results: Before surgery, 94% of the patients had grade III or IV pain. At last follow-up, 93% of them grade 0 or I. The gain in pain was greatest for patients with severe carpitis. At last follow-up, the wrist was stiff; stiffness basically involved flexion with 43° pre and 27° postoperatively, radial inclination 13° pre and 9° postoperatively, and pronation in patients with advanced Larsen grade preoperatively. Extension, ulnar inclination, and supination were improved 5° to 10°. Extension of the synovectomy to carpal joints had a stiffening effect. Before the operation, 25 wrists were in Larsen grades 0, 1 and 2 and 48 wrists were in Larsen grades 3 or 4. At last follow-up, there were nine wrists in Larsen grades 0, 1, or 2 and 64 in Larsen grades 3 or 4. Carpitis thus continued to evolve and the height of the carpus declined. Ulnar translation of the carpus progressed a mean 2 mm. Spontaneous radial inclination of the wrist was aggravated by a mean 3°. The frontal position of the wrist was better after transfer of the long radial extensor of the carpus on the short radial extensor of the carpus than for transfer on the ulnar extensor of the carpus or without transfer.

Discussion: Our pain results are in agreement with data in the literature but we did not observe preserved or improved mobility. Extended synovectomy appeared to have a stiffening effect. Progression of the ulnar translation of the carpus was less pronounced with simple resection of the head of the ulna. It was better to transfer the long radial extensor of the carpus on the short radial extensor of the carpus to correct for frontal deviation of the carpus.

Purpose: Is prevention of postoperative venous thrombosis using low-molecular-weight heparin (LMWH) sufficient in orthopaedic and traumatology units?

Material and methods: Between 1995 and 2000, all patients undergoing orthopaedic or traumatology procedures involving the lower limb underwent a venous control the sixth day after surgery: RPO with phlebography if positive until September 1996 then duplex Doppler of the lower limbs. In all 755 patients, mean age 68 years (34–90), undergoing planned orthopaedic procedures (341 THA, 135 TKA, 111 tibial osteotomies, 66 single compartment prostheses, cruciate surgery) or procedures for trauma (56 femoral neck, trochanter, bimalleolar, etc.) were included.

Results: A total of 118 cases of deep vein thrombosis were discovered giving an incidence of 16%. The deep vein thrombosis was in the sural territory in 95 cases (posterior tibial, fibular, vastus and/or anterior tibial) but there were also 13 cases of proximal thrombosis in the iliofemoral or femoral localisations. The large majority of the cases were homolateral to the surgical side, eight were found in the other limb. In this series, the venous risk differed from one surgical procedure to another (for the same operator): 11% for THA, 22% for TKA (without tourniquet) and 17 to 12.5% for tibial osteotomies with tourniquet (valgisation and transposition of the anterior tuberosity), 13.5 % for single compartment prostheses with tourniquet. Our oldest patient was 90 years old and was treated by intermediary arthroplasty for a cervical fracture. The youngest were 34 years old for anterior cruciate ligament surgery or valgisation osteotomy and 38 and 39 years for THA subsequent to advanced necrosis. Finally, there was no statistical difference by sex.

Conclusion: Systematic use of duplex Doppler examination of both limbs postoperatively revealed a large number of deep vein thrombosis patients despite systematic use of LMWH which certainly modified their clinical presentation. These patients were then given adapted treatment which led to regression of the complications: postphlebitis syndrome and pulmonary embolism with the risk of medicolegal complications.