We present cases of Alveolar Soft Part Sarcoma, one in the upper limb the other in the lower limb, in two young females. Both were treated in the same centre by the same consultant. The first is the case of a 33 year old female with a swelling in the right triceps present for 7 months before presentation to our centre. The time between diagnosis of possible tumour and biopsy was less than a month. Biopsy revealed a trojani grade 2 tumour and there were no metastases prior to wide excision. She received radiotherapy and has no metastases on follow up. Post therapy she is left with neurological pain and a rash on her face after radiotherapy. The second case is that of a 25 year old female presenting, with a swelling in the right thigh, after 12 months including a 6 month history of shortness of breath. She had a family history of pancreatic cancer. Biopsy revealed a trojani grade 3 tumour and imaging revealed lung metastases. She went on to have chemotherapy. She later developed bone metastases.
There were no focal neurological signs and lumbar spine movements were normal. However, she did have some pain inhibition in her proximal muscles and difficulty weight bearing in her leg. Lumbar spine x-rays showed grade II spondylolytic spondylolisthesis at L5/S1. MR scan of the lumbar spine confirmed this with some facet joint degeneration. She was sent back for more physiotherapy. Six months later she presented with increasing pain in the right hip and a lump in the right groin. Subsequent MR scan showed a large 20cm x 15cm x 10cm lobulated soft tissue mass within the right obturator space extending through the foramen to lie in the adductor space with infiltration into right hip joint. She had a radical resection but later developed lung metastases.