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Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_7 | Pages 103 - 103
1 Jul 2020
Sheth U Nelson P Kwan C Tjong V Terry M
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Traditionally, open reduction and internal fixation (ORIF) and hemiarthroplasty (HA) have been the surgical treatments of choice for displaced proximal humerus fractures (PHF) despite high rates of fixation failure and tuberosity nonunion, especially in the elderly population with poor bone quality. Recently, there has been a significant increase in the use of reverse total shoulder arthroplasty (RTSA) as a treatment option in both acute fractures, as well as a salvage procedure for fracture sequelae (i.e., malunion, nonunion, fixation failure, tuberosity non-union). Despite the growing enthusiasm it remains unknown whether functional outcomes after RTSA as a salvage procedure are similar to those following acute RTSA. As a result, the purpose of this systematic review was to compare functional outcomes after RTSA as a primary versus salvage procedure for displaced PHF in the elderly.

A literature search of the electronic databases EMBASE, MEDLINE, and PubMed was conducted to identify all studies comparing RTSA as a primary treatment for displaced PHF and as a salvage procedure for failed initial management. Only studies with a minimum follow-up of two years were included. Data pertaining to range of motion, patient reported outcome measures and complications were extracted from eligible studies and entered into a meta-analysis software package (RevMan version 5.1, The Cochrane Collaboration) for pooled analysis. The Newcastle-Ottawa Scale (NOS) was used to evaluate the quality of eligible studies.

The search identified four studies consisting of 200 patients with a mean age of 73.3 years and a mean follow-up of 3.2 years. There were a total of 76 patients (75% female) who underwent acute RTSA following displaced PHF, while 124 patients (77% female) required salvage RTSA for failure of initial treatment. Primary RTSA was found to have significantly higher American Shoulder and Elbow (ASES) (P = 0.04), Constant (P = 0.01) and University of California at Los Angeles (UCLA) (P = 0.0004) scores compared to salvage RTSA. Forward flexion (P = 0.001) and external rotation (P< 0.0001) were significantly greater amongst those undergoing RTSA acutely versus as a salvage procedure. The odds of having a complication (e.g., infection, dislocation, fracture) were 76% lower amongst those who had primary RTSA compared to salvage RTSA (P = 0.02). The overall quality of eligible studies was moderate to high.

Based on the current available evidence, elderly patients with displaced PHF have significantly greater range of motion, higher patient reported outcomes and lower risk of complications with primary RTSA compared to those undergoing RTSA as a salvage procedure. Additional prospective studies are warranted to confirm these findings.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_7 | Pages 21 - 21
1 Jul 2020
Hartwell M Nelson P Johnson D Nicolay R Christian R Selley R Tjong V Terry M
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Recent studies have described safe outcomes for short-stays in the hospital after total shoulder arthroplasty. The purpose of this study is to identify pre-operative and operative risk factors for hospital admissions exceeding 24 hours.

The American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database was queried from 2006 to 2016 for the current procedural terminology (CPT) billing code related to total shoulder arthroplasty. Patients were then grouped as either having a length of stay (LOS) equal to or less than 24 hours or greater than 24 hours. Patients admitted to the hospital prior to the day of surgery were excluded. Patient demographics, co-morbidities, and operative time were then analyzed as risk factors for a hospital stay exceeding 24 hours. Pre-operative co-morbidities included body mass index (BMI), diabetes, smoking, chronic obstructive pulmonary disease (COPD), congestive heart failure (CHF), hypertension, dialysis, chronic steroid or immunosuppressant use, bleeding disorders, and American Society of Anesthesiologists (ASA) Classification. Univariate and multivariate analyses were then performed to identify risk factors associated with 30-day readmission.

14,339 patients met inclusion criteria and 6,507 (45.3%) had a hospital LOS less than or equal to 24 hours. The mean length of hospitalization was 1.95 ± 1.88 days, the average age was 69 ± 9.7 years old, and 56.9% of the patients were female. Following a risk adjusted multivariate analysis, increasing age (odds ratio [OR], 1.03, 95% confidence interval [CI], 1.02–1.03), ASA classification (OR, 1.50, 95% CI, 1.41–1.60), diabetes (OR, 1.69, 95% CI, 1.43–1.99), COPD (OR, 1.35, 95% CI, 1.16–1.57), CHF (OR, 2.67, 95% CI, 1.34–5.33), dialysis (OR, 2.47, 95% CI, 1.28, 4.77), history of a bleeding disorder (OR, 1.50, 95% CI, 1.20–1.88), or increasing operative time (OR, 1.01, 95% CI, 1.01–1.01) were identified as independent risk factors for hospital lengths of stay exceeding 24 hours. Male gender was identified as a protective factor for prolonged hospitalization (OR, 0.50, 95% CI, 0.46–0.53).

This study identifies patient demographics, co-morbidities, and operative-relative risk factors that are associated with increased risk for a prolonged hospitalization following total shoulder arthroplasty. Female gender, increasing age, ASA classification, operative time, or a history of diabetes, COPD, CHF, or history of a bleeding disorder are risk factors hospitalizations exceeding 24 hours.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIII | Pages 67 - 67
1 May 2012
Bowsher J Nelson P Clarke PI McTighe T Woodgate I Turnbull A Keppler L Donaldson T
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Hip simulator studies on MOM bearings have historically involved ‘custom’ cetabular cups. I.e. having neither beaded layers nor biological coatings.

The aim of this study was to investigate wear using such MOM bearings and evaluate the potential wear and evaluate the potential for error in the gravimetric assessment.

Six x 38 mm HC Co-Cr bearings were supplied (Global and IO International Orthopaedics). The cups were received in ‘off-the-shelf’ condition with a cast Co-Cr beaded/HA-coated backing. To remove the HA-coating, the cups were pre-soaked in lemon juice for 4 days (articular surfaces shielded). Custom plastic fixtures were machined to fit the beaded contours of the cups. Test duration was 5Mc inorbital hip simulator (Shore-Western). MOM wear was estimated from serum ion contamination. Serum samples were digested and assessed using ICP/MS (Weck Labs Inc, CA).

The majority of the HA-coating was removed from the cups after four days of soaking inlemon juice after 21 days of soaking all cup weights appeared atable (within 1 mg). Reflected-light microscopy (RLM) showed no descernible signs of HA and the total weight loss due to HA remval averaged∼400mg.

During hip simulator there was no visual evidence of lost or broken beads, 3rd body abrasion etc (Sa<30nm). Both gravimetric and metal ion analysis showed consistent wear trends for all MOM cups. The MOM with the highest wear (predicted by ion analysis) demonstrated 1.2 mm (3)/Mc)OWR) at 5Mc. In comparsion, gravimetric analysis predicted an OWR of 1.3 mm (3)Mc for the same MOM, a difference of only 8%. Soaking beaded-HA cups in lemon juice and BCS proved effective in removing the coating.

The beaded cups remained stable in weight during the wear study and caused little discrepancy in gravimetric analysis (8%).

The method described did not lead to breaking of beads, elevated 3rd-body abrasion, cup damage or distorted wear scars.