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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_11 | Pages 37 - 37
1 Oct 2019
Nahhas CR Chalmers PN Parvizi J Sporer SM Berend KR Moric M Chen AF Austin M Deirmengian GK Morris MJ Culvern C Valle CJD
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Background

The purpose of this multi-center, randomized clinical trial was to compare static and articulating spacers in the treatment of PJI complicating total knee arthroplasty TKA.

Methods

68 Patients treated with two-stage exchange arthroplasty were randomized to either a static (32 patients) or an articulating (36 patients) spacer. A power analysis determined that 28 patients per group were necessary to detect a 13ยบ difference in range of motion between groups. Six patients were excluded after randomization, six died, and seven were lost to follow-up prior to two years.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 29 - 29
1 Jun 2012
Cipriano C Brown N Michael A Moric M Sporer S Valle CD
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Introduction

Serum erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), and synovial fluid white blood cell (WBC) count and differential are effective in diagnosing periprosthetic joint infection (PPJI); however their utility in patients with inflammatory arthritis is unknown. The purpose of this study is to determine the utility of these tests in patients with inflammatory arthritis.

Methods

934 Consecutive revision hip and knee arthroplasties were prospectively evaluated for PPJI. 202 Cases were excluded due to acute post-operative or hematogenous infection. 690 Patients had non-inflammatory and 42 had inflammatory arthritis. Receiver operating characteristic (ROC) curves were used to establish optimal ESR, CRP, WBC, and % neutrophil values for diagnosis of PPJI, and the area under the curve (AUC) was calculated to determine the overall accuracy.