The purpose of this study was to investigate the outcome after surgical therapy of patients suffering from HO of the hip after treatment in ICU. We retrospectively examined 39 patients with heterotopic ossification of the hip (18 bilateral and 21 unilateral). All patients have had history of ICU treatment for several reasons, such as craniocerebral injury (35 patients-90%), 2 patients with Guillain-Barre syndrome (5%), 1 patient with pulmonary druse (2.5%), and 1 patient with inflammatory bowel disease (2.5%). They all underwent surgical removal of HO and postoperative irradiation therapy. On the basis of plain radiographic findings, we evaluated the recurrent ossification after an 18-month follow-up period. The evaluation of the average 18-months follow-up period showed relief of pain and clear improvement of range of motion in most of our patients. Specifically, improvement in the range of movement was observed in 41 hip joints (71.93%) in contrast to 16 hip joints (28.07%) that did not show any alteration post-operatively. No lesion re-occurrence was observed. There was only one complication of peroneal nerve paresis following HO excision. The majority of our patients that were treated with surgical excision of the ectopic bone around the hip joint significantly improved their range of joint movement and were relieved from pain. Surgical excision seems to provide a superior quality of life in these patients, as they have a high risk for major complications due to their poor level of mobility.
This study compares the endoscopic carpal tunnel release with the conventional open technique with respect to short and long-term improvements of functional and clinical outcomes. We assessed 72 outpatients diagnosed with carpal tunnel syndrome. Thirty-seven patients underwent the endoscopic method according to Chow and 35 were assigned to the open method. Improvement in symptoms, severity and functionality were evaluated shortly preoperatively (at two days, one week and two weeks) and one year after using the Symptom Severity Scale, Symptom Severity Status and DASH questionnaire. Changes in clinical outcomes (grip strength, key pinch and two-point discrimination test) were evaluated one year postoperatively. Complications were also assessed. Both groups showed similar improvement in all but one outcome one year after the release; increase in grip strength was significantly higher for the endoscopic group. The endoscopic method was also associated with a significantly faster short-term improvement. Separate analysis of the questionnaire components referring to pain reveals that the delay of improvement in the open group is due to the persistence of pain for a longer period. Paresthesias and numbness decrease shortly after the operation with comparable rates for both groups.
The objective of this study was to evaluate the functional outcome of the elbow joint in patients with heterotopic ossification of the elbow joint who underwent surgical excision of pathologic bone. From 5/1994 to 12/2006, 24 patients (33 joints) with heterotopic ossification of the elbow joint were evaluated. All patients were attended in the Intensive Care Unit (ICU). The patient\’s age ranged from 19–48 years (mean; 32 years) The median ICU hospitalization was 3 weeks. In nine patients both elbows were affected. Unilateral involvement was equally noticed to the right (seven cases) and the left elbow (eight cases). The DASH SCORE and the range of motion were used for the evaluation of the results. All patients underwent surgical treatment in order to extract heterotopic bone and to improve the range of motion of the affected elbow joint. Postoperatively 18 out of 33 operated elbow joints (54.54%) demonstrated improvement of the range of motion, whereas no improvement was observed in the remaining 15 elbow joints (45.45%). Higher DASH SCORE was obtained in 19 out of 24 patients (79.17%). Surgical excision of the ectopic bone around the affected elbow significantly improves the range of motion of the joint providing better use of the upper extremity and therefore a superior quality of life in these patients.
The aim of the study to analyze the circulating white blood cells including the intensity expression of surface receptors and cytoplasmic molecules in patients underwent total hip replacement, with either aseptic or septic loosening of hip prostheses in order to identify cell-surface and cytoplasmic markers that could be indicative of early loosening. Flow cytometry was performed in whole peripheral blood samples of 20 patients with loosening (10 septic and 10 aseptic). Ten healthy individuals served a control group. The CD62L, CD18, CD11a, CD11b and CD11c expressions were evaluated. The mean fluorescence intensity (MFI) of CD 18 was decreased on all leukocytes subsets compared to control group. For patients with aseptic loosening we demonstrated an increase of MFI for CD11b in granulocytes and for CD11c in monocytes and granulocytes compared to control group. In patients with septic loosening an increase of MFI for CD 11c was observed in monocytes compared to control group. The comparison between aseptic and septic loosening showed a statistically significant lower CD18 MFI value in granulocytes for aseptic loosening. A trend towards lower MFI values of CD 62L in lymphocytes and granulocytes were observed in aseptic but not in septic loosening patients compared to control group. The present study is the first study in published literature to demonstrate cell surface and cytoplasmic markers in peripheral blood indicative of loosening of THAs by means of flow cytometry.
The purpose of this study is to evaluate the long-term results of the surgical treatment of cubital tunnel syndrome by comparing the in-situ decompression and release of the ulnar nerve with or without partial medial epicondylectomy and the anterior transposition and release respectively.
17 patients were lost to follow-up. 108 patients were clinically assessed. Comparing the results among different surgical procedures, an improvement of at least one McGowan grade was obtained in 26 of 30 patients treated with simple decompression, in 29 of 35 patients treated with release and anterior transposition of the nerve and in 38 of 43 patients treated with release and medial epicondylectomy. The results of this study show that the possibility for complete recovery is inversely related to the initial neuropathy grade. Partial medial epicondylectomy is a valuable surgical procedure for treating grade I to IIB ulnar neuropathy because is an anatomic method with minimal nerve manipulation preserving regional blood supply.
Total hip arthroplasty (THA) in neglected congenital dislocation of the hip (CDH) constitutes a challenging procedure, with surgical difficulties and complications. The purpose of this study was to analyse the complications of THAs in CDH. Between June 1983 and September 2002, 418 THAs-were performed in 356 patients with CDH, with a mean follow-up 108 (7–237)months. The mean age at surgery was 53.3 (24–79) years with 325 females and31 males. 83 patients had CDH in high position. 307 arthroplasties were cementless, 39 cemented and 72 hybrids. 40 stems were custom made. The cup always was positioned at the true acetabulum. 24 shortening osteotomies of the femur, 8 corrective supracondylar and 6 trochanteric osteotomies were performed. Preoperatively the average Merle d’Aubigne-Postel hip score was 1.1 for pain, 4.8 for range of motion and 3.1 for walking ability. Postoperatively the average hip score was 5.2, 4.7 and 5.3 respectively. The average length discrepancy was 8 cm (3–12) preoperatively and 1.5 cm remained in 8 patients. Complications included 7 intraoperative fractures of the femur, 12 dislocations, 4 peroneal nerve palsies that recovered, 25heterotopic ossifications, 7 deep vein thromboses, 3 pulmonary embolisms, early mechanical loosening in 4 cemented and 10 cementless cups and 3infections. Complications were diminished dramatically last years due to improved surgical technique, new available implants and preoperative evaluation of the hip with CT and CAD-CAM-CAE study that allowed better surgical planning with trial stem implantation from a series of stem designs and custom made femoral components manufacturing
We present our experience from use of acetabular reinforcement rings in revision total hip arthroplasty when bone defects are present. From 1987 to 2000, acetabular reinforcement rings were utilized in 59 revisions, in 52 patients with a mean age of 60 years (31–81). In 48 hips, Ganz rings were used and in 11 hips, Burch-Sch-neider rings. For the existing defects of the acetabulum, morsellized bone allograft was used. The patients were evaluated clinically with the modified Merle d’ Aubigne-Postel scale and radiologically with the criteria of Gill-Sledge-Muller. Acetabular reconstruction was successful in 51 of 59 hips (86.5%) after a mean follow-up period of 7 years (2–15). One of the 11 Burch-Schneider rings failed (9.1%) and 7 of the 48 Ganz, raising the failure rate of this ring up to 14.6%. Complications included dislocation in 5 cases, deep vein thrombosis in 2, superficial infection in 1 and pubis rami fracture in 2 cases. Reinforcement rings in our opinion could be of valuable help in reconstruction of the bone deficient acetabulum. Although in this study, it is not possible for these two rings to be directly compared, Burch-Schneider one appears to have a more clear role and lower failure rate. However, in order to evaluate in a more reliable way the true fate of the acetabular reinforcement rings, especially in the presence of the limited role of biological fixation, longer follow-up time is needed.
This study of surgically treated distal tibia fractures was undertaken to compare the internal fixation with the two external fixation methods. There were 40 patients with 41 pilon fractures. The mean age was 51.2 years (18–76). 17 of the 40 patients-14 from vehicular accident, 3 from fall – were treated with an ankle-spanning half-pin external fixator (11C, 6B, 11 Weber B- 5 C, 1IIIa, 5I, 6II). 11 patients-10 from vehicular accident, 1 from fall- were treated with a single-ring hybrid ankle-spanning external fixator (9C, 2 B, 6 Weber B-4 C, 5I, 2II). 13 patients-10 from vehicular accident and 1 from fall- were treated with an epiunion plate (1A, 8B, 4C, 5I, 3II, 10 Weber B- 1C). The mean follow-up was 4.2years (1–8). Fracture union was defined as having three cortices bridging on the plain radiographs for a patient who was able to bear full weight. Non union was defined as a fracture that did not heal within a year. Fracture union was achieved for 36 of the 41 fractures. Three patients with external fixator, one with hybrid and one with plate had septic pseudarthrosis. Fractures in the external fixator and hybrid groups had a tendency to lose the reduction. Four patients with external fixator had delayed union and have lost range of motion in the ankle. Five patients in the external fixator group are candidates for ankle arthrodesis due to arthritis. The ORIF and hybrid fixator were equally efficacious in achieving bony union and not to lose range of motion in the ankle. Fractures in the external fixator with the ankle – spanning had higher rate of delayed union and loss of motion in ankle. The choice of the external fixator is dependent on the surgeon and the type of the fracture. However the patient must be followed up for the stability of the system.
Total hip arthroplasty (THA) in neglected congenital dislocation of the hip (CDH) constitutes a challenging procedure, with surgical difficulties and complications. The purpose of this study was to analyse the complications of THAs in CDH. Between June 1983 and September 2002, 418 THAs were performed in 356 patients with CDH, with a mean follow-up 108 (7–237) months. The mean age at surgery was 53.3 (24–79) years with 325 females and 31 males. 83 patients had CDH in high position. 307 arthroplasties were cementless, 39 cemented and 72 hybrids. 40 stems were custom made. The cup always was positioned at the true acetabulum. 24 shortening osteotomies of the femur, 8 corrective supracondylar and 6 trochanteric osteotomies were performed. Preoperatively the average Merle d’Aubigne-Postel hip score was 1.1 for pain, 4.8 for range of motion and 3.1 for walking ability. Postoperatively the average hip score was 5.2, 4.7 and 5.3 respectively. The average length discrepancy was 8 cm (3–12) preoperatively and 1.5 cm remained in 8 patients. Complications included 7 intraoperative fractures of the femur, 12 dislocations, 4 peroneal nerve palsies that recovered, 25 heterotopic ossifications, 7 deep vein thromboses, 3 pulmonary embolisms, early mechanical loosening in 4 cemented and 10 cementless cups and 3 infections. Complications were diminished dramatically last years due to improved surgical technique, new available implants and preoperative evaluation of the hip with CT and CAD-CAM-CAE study that allowed better surgical planning with trial stem implantation from a series of stem designs and custom made femoral components manufacturing.
Natural history studies of scaphoid non-unions focus on symptomatic non-unions. As a consequence, neither the real incidence nor the long-term sequels of asymptomatic scaphoid pseudarthrosis have been sufficiently studied. Three adult patients (38, 40 and 79 years of age) with long-standing asymptomatic scaphoid non-union are presented. The lesions were identified in radiographs taken in the accident and emergency department after new injuries. All patients could recall the initial fracture, which occurred 17.5, 20 and 40 years respectively before the index examination. Although all the patients were heavy manual workers and in two the non-union occurred in their dominant upper extremity, none could recall pain during activities. Radiographic evidence of carpal malalignment and/or arthritis was noted in all patients. At the 3-month follow-up after the new injury all patients remained asymptomatic with only mild limitations in the range of motion. With evolving trends of ORIF in unstable scaphoid fractures, there is need for larger-scale natural history studies that include asymptomatic scaphoid non-unions. Such lesions are currently poorly understood and their treatment (if one is needed) remains unclear.
Although primary flexor tendon repair in children yields satisfactory results, some children end up with poor function because of delay in diagnosis, technical difficulties and the inability to follow a structured rehabilitation program. The aim of this study is to evaluate the functional outcome after two stage reconstruction with the modified Paneva technique (which includes creating a loop between the proximal stumps of Flexor Digitorum Profundus and Superficialis in the first stage and reflecting the latter as a “pedicled” graft through the pseudosheath created around the silicone rod, in the second stage) in children. Nine patients (nine digits) with a mean age of 8.2 year (range 3–15) were treated for zone II lesions. Their pre- operative status in the Boyes and Hunter scale was grade 2 in three, grade 3 in three, grade 4 in one and grade 5 in two patients. After a mean of 42 months of follow-up (minimum 12 months), according to the Buck-Gramco scale there were four excellent, four good and one poor result and according to the revised Strickland scale three excellent, five good and one poor. Children over the age of 10 had slightly improved Total Active Motion (mean +35°) compared to younger patients. No significant length discrepancies were noted. Two postoperative infections were treated and one graft-related re-operation was necessary. Staged flexor tendon reconstruction in children is technically feasible and efficient. Delaying such a reconstruction in younger children does not seem justified.