The mean age of diagnosis was 14.6 months (range 4–72). Many of the late referrals had risk factors for DDH.
A marked reduction in osteomyelitis was noted over the twenty-four year incidence of the study. In addition, a shift in the causative organism was noted from an incidence of H Influenzae in the 70’s of up to 30%, to less than 5% in the 90’s. The treatment regime changed markedly over the course of the study period, with a significantly reduced duration of hospital stay reflecting the move away from protracted periods of hospitalisation.
Breech presentation is historically associated with an increased incidence of hip Dysplasia (6.6%–9.6%), but the effect of vaginal breech delivery on the development of hip dysplasia is unknown. In the Irish Republic, the proportion of breech presentations delivered by caesarean section is now over 90%. If the mechanical trauma of vaginal delivery is a significant event in the aetiology of DDH in breech presenters, caesarean section should be protective. We tested this hypothesis by a prospective study in infants presenting in the breech position who were delivered by caesarean section, during the 2002 calendar year. There were 108 infants in the breech position at the time of delivery during this period; all but two of these (excluded from the study) were delivered by caesarean section. 50 were male and 56 were female. The mean duration of pregnancy at delivery was 37 weeks. An initial examination was performed in all cases within the first 48 hours postpartum, and treatment in a Pavlik harness commenced where there was clinical instability. Standardised AP and BIR views of the pelvis were taken at 4 months after birth, in all 106 cases. The acetabular index (AI) was measured on both sides. There was only one case of hip dislocation at birth (bilateral dislocation in a first-born female infant). In 7 cases the initial examination was suspicious for instability, and patients were treated in Pavlik harness; in five of these cases another recognised risk factor (first-born female, family history) was also present. Two of these cases were found to have evidence of instability at 4 months, and underwent treatment by closed reduction and spica casting. For the entire group, the mean acetabular index (212 hips) was 23 degrees (range 17 to 36 degrees). Among those with signs suggestive of instability, the mean AI was 28 degrees. Only one patient had an AI >
30 degrees. Among those with no other risk factors, the mean AI was 22 degrees (range 17 to 28). Our prospective study suggests that the incidence of DDH is markedly lower in breech presenters delivered by caesarean section (<
3%) that that reported for breech presenters as a whole. The three patients in our group with DDH had other risk factors present. We conclude that caesarean section may be protective for the development of DDH in infants who present in the breech position.
The number of skate related injuries has seen a resurgence in the western world with almost 51000 patients in 1999 presenting to US hospitals with a skateboard related injury, almost 90% of these being male and almost 70% of these are orthopaedic related injuries. Protection , particularly wrist guards, elbow pads, knee pads and recognized helmets are all necessary in protecting the young child against orthopaedic injuries. However despite these physical barriers little training or supervision exists in adequately educating children as to the dangers of these devices. Having observed an increased number of referrals to our Accident and Emergency Dept with fractures sustained whilst roller-blading and skateboarding we set about prospectively evaluating the epidemiology and nature of such injuries. 100 successive referrals to the orthopaedic service as a result of roller/skate injuries were evaluated. Childs age, sex, time using apparatus, mechanism of injury, and whether the injury occurred in a dedicated skatepark or on the street was recorded. Whether the child was wearing any form of protective gear and what type was also recorded. The type of fracture and its treatment and follow up was evaluated. All results were recorded on standard excel spreadsheets and statistical analysis was performed using Instat statistics (Graphpad USA 2002). The Male to female ratio in street injuries was 1:1, whereas in ramp injuries 4:1. 60 injuries occurred on the street whereas 40 occurred whilst using the ramps. The mean age was 11.4yrs. The mean length of time using rollerblades/skateboards was 20 and 19 months for street and ramps respectively. The number of children wearing some form of protective gear shows only 20 children out of the 100 studied wore gear, of these 15 wore helmets only. The treatment initiated shows almost 80% of ramp related injuries required formal manipulation under general anaesthesia or open reduction and internal fixation, where as only 25% of street fractures required this form of treatment, The usage of ramps demonstrates an increased relative risk of 4.26 (95% CI 3.5–5.1) This study shows that skateboards and rollerblades still constitute a major component of childhood fracture admissions. Only 20% of children use some form of protective gear whilst skating, this needs to be addressed on a national level. The wearing of helmets whilst protecting the child against head injury do not prevent serious orthopaedic injuries. Wrist guards should be worn by all children skating as the fall onto outstretched hand still remains a childs defensive mechanism when thrown off balance. Almost 75% of all fractures involve the wrist or the forearm. We urge better education and a tighter supervision of children whilst skating. Dedicated skateparks should only be used by experienced and older children and they should at least be supervised during their first attempts at using the parks, 85% of ramp injuries occurred during first or second time users. A child using a skatepark particularily for the first time is three times more likely to sustain a fracture, and almost 4 and a half times more likely to require definitive surgical treatment of this fracture. This constitutes a huge orthopaedic burden as well as it’s associated morbidity and financial costs to the health service. Children should be encouraged to use limb protectors as well as helmets whilst skating and should be supervised more closely during their initial attempts.
A retrospective study was undertaken in our unit to investigate any change in osteomyelitis trends in the last ten years (1991-2001). These results were then compared to 3 previous studies conducted by our unit on childhood osteomyelitis, 1977-1979 45 cases(O’Brien et al)1, 1980-87 (84 cases) and 1988-1991 (54 cases). 149 patients were identified from hospital discharge database with a diagnosis of osteomyelitis between 1991 and 2001. 136 fully completed charts were discovered and included in the study. 22 children did not fulfil the criterion for the diagnosis of acute or subacute osteomyelitis and were excluded. Cellulitis was the actual diagnosis 18/22 cases, leukaemia or other neoplasm in 4/22 cases. 28% of the children 32/114 had acute haematog-enous osteomyelitis with classical signs and symptoms the remaining 72% fell into the subacute osteomyelitis category as described by Gledhill. Table 1 shows the comparison between the 4 studies. 89% of patients underwent 3 phase bone scanning, and 90% of these were positive. Blood cultures were performed in 87% of patients and were positive in 8.5%, 2 patients being positive and symptomatic of Nesseria meningitis, 4 Staph aureus, 2 Strep Pneumonia, 1 staph epidermidis and 1 E.Coli. As compared to previous 3 studies no case of haemophilus influenza type B was encountered. Aspiration was performed in 22 patients and 18 demonstrated bacteria, the two commonest pathogens were Staphylococcus aureus 66% and epider-midis 16%. 8 patients underwent surgical debridement or drilling if clinically septic or because of failure to improve despite medical treatment. Initial antibiotic treatment comprised of i.v. penicillins and oral fucidin in 92% of patients, the remainder receiving cephalosporins as favoured by physicians or erythromycin if history of hypersensitivity. Antibiotics arethen tailored to clinical picture or culture results. Table 2 shows the changing duration pattern of antibiotic administration. There were four cases of complications, 2 cases of chronic osteomyelitis and 2 cases of limb shortening both around the knee joint. Our results correlate well with other authors. Surgery has an ever-decreasing role in the management of osteomyelitis, with conservative antibiotic management and splintage being the treatment of choice. Subacute osteomyelitis is an ever-increasing entity as reflected in other studies. The incidence of osteomyelitis presenting to our unit has fallen to 2.34 per 10000 per yea. A possible explanation may lie in altered host pathogen interactions, increased host resistance, the frequent administration of broad-spectrum antibiotics in general practice. Increased population wealth as experienced in Ireland in the last 8 years may also have a role.
The pathophysiology of discogenic low back pain is poorly understood. The morphological changes occurring in disc degeneration are well documented but unhelpful in determining if a particular degenerate disc will be painful or not. Herniated intervertebral disc tisssue has been shown to produce a number of pro-inflammatory mediators and cytokines. No similar studies have to date been done utilising disc material from patients with discogenic low back pain. The aim of this study was to compare levels of production of interleukin-6 (IL-6), interleukin-8 (IL-8) and Prostaglandin E2 (PGE2) in disc tissue from patients undergoing discectomy for sciatica with that from patients undergoing fusion for discogenic low back pain. Tissue from 50 patients undergoing discectomy for sciatica and 20 patients undergoing fusion for discogenic low back pain was cultured and the medium harvested for subsequent analysis using an enzyme linked immunoabsorbent assay method. Statistical analysis of the results was performed using the Mann-Whitney test. Disc specimens from both experimental groups produced measurable levels of all three mediators. Mean production of IL-6, IL-8 and PGE2 in the sciatica group was 26.2±75.7, 247±573 and 2255±3974 respectively. Mean production of IL-6, IL-8 and PGE2 in the low back pain group was 92±154, 776±987 and 3221±3350 respectively (data = mean production pg/ml ± 1 standard deviation). There was a statistically significant difference between the levels of IL-6 and IL-8 production in the sciatica and low back pain groups (p<
0.006 and p<
0.003 respectively). The high levels of pro-inflammatory mediator production found in disc tissue from patients undergoing fusion for discogenic LBP may indicate that nucleus pulposis pro-inflammatory mediator production is a major factor in the genesis of a painful lumbar disc. This could explain why some degenerate discs cause LBP while other morphologically similar discs do not.
Acute haematogenous osteomyelitis remains a significant cause of morbidity in the paediatric population. The clinical presentation has changed, however, over the last number of decades. The typical picture of established osteomyelitis is less commonly seen. Children more often present with a less fulminant picture. The treatment of acute haematogenous osteomyelitis remains controversial. Antibiotic therapy, initially intravenous, then orally, is the gold standard. Hover, the role of surgery is unclear. Some centres, particularly in North America treat 25–40% of patients surgically. We present our experience with acute haematogenous osteomyelitis in children over a three year period. The total number of patients was forty-five. The mean age was 6.1 (range 6 months to thirteen years). The most common isolated organism was Staphylococcus Aureus. The mode of treatment was intravenous antibiotics for two weeks, or until clinical, and laboratory evidence of improvement, and the oral antibiotics for six weeks. No patients required surgical interventioin. All patients made a satisfactory recovery. We conclude that the treatment of acute haematogenous osteomyelitis in the paediatric population should consist of antibiotic therapy only, and that there is no place for surgery.