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Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 337 - 337
1 May 2010
Rampal V Wicart P Koureas G Erdeneshoo E Seringe R
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Thanks to neonatal screening, idiopathic congenital dislocation of the hip (CDH) is generally diagnosed and treated at an early age. Despite this measure, late diagnosis of CDH still occurs. The goal of this article is to analyse the results of Petit-Morel’s closed reduction (CR) technique in the treatment of CDH diagnosed between 1 and 5 years old. We reviewed 72 hips in 60 patients. The treatment method was the same for all patients, beginning by bilateral longitudinal traction to achieve ‘presentation’ of the hip. It was followed by ‘penetration’ in a hip spica cast made under general anesthesia. The third step was an almost systematic surgical treatment of the remaining acetabular dysplasia. Results were evaluated using the radiological Severin score. Average follow-up was 11.9 years. The failure of CR occurs only twice. In this two cases, open reduction showed intraarticular obstacles to reduction. The only case of avascular necrosis (AVN) occured in one of this two failures of CR. At last follow-up, 95.8% of hips were rated as normal, or midly deformed. Young age at treatment significantly influenced the prognosis in our series. Neither the gender nor the height of the dislocation did appear to have any influence on the result. The patients which did not undergo a periacetabular osteotomy were significantly younger than the other one in the series. Pelvic osteotomy is an integral part of the method, as after 18 months many hips have lost their capacity to correct the remaining dysplasia. However, we only perform this osteotomy if the hip shows no sufficient correction during the semesters following the reduction od the dislocation. Considering Severin score, it is impossible to privilege closed or open reduction, as the results of both methods are close. However, in case of failure of reduction, which occurs in both methods, a second open reduction is much more difficult to achieve than and open reduction in a hip first treated by closed reduction. The results of this second surgery on the hip are poorer, with higher rates of AVN. Moreover, long-term functional and radiological deterioration of the hip is higher after open reduction than closed reduction. Lowest rates of AVN are reported after traction followed by closed reduction compared with exteporaneous reduction or open reduction, thanks to progressive reduction of the hip. Finally, mention should be made of the cost of the treatment. Petit-Morel’s protocole is expensive, both because of the duration of stay in the hospital, and by indirect costs as parent adaptation of its work during the treatment. The cost of open reduction is lower. However, considering the prooved better results of the closed method, requiring lower rates of further surgical procedure, we think that this method is the one to be promoted for treatment of CDH in children between 1 and 5 years old.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 144 - 144
1 Mar 2006
Koureas G Zacharatos S Petsinis G Korovessis P
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Objectives: To investigate the influence of backpacks on the spine curves, shoulder level, trunk and back pain in schooladolescents.

Methods: 1263 students, aged 12 to 18 years, who carried backpacks over one or both shoulders to the school were asked for dorsal (DP) and/or low back pain (LBP). Kyphometer and Scoliometer were used to measure craniocervical angle (CCA), thoracic kyphosis, lumbar lordosis and shoulder level shift(BL) and biplane trunk deviations. Logistic and multinomial logistic analysis, t-test, Wilcoxon and chi-square tests were used for statistics.

Results: Backpacks decreased CCA (P< 0.001), and increased BL-shift(P< 0.001), and biplane trunk shift (P< 0.03). Girls suffer 6(P=0.001) times more from DP than boys. Students carrying backpacks asymmetrically suffer 3(P=0.035) and 5(P=0.014) more from DP and LBP respectively, than those symmetrically carrying. With increasing BMI decreases the possibility for DP at 10%(P=0.047) and increases at 10%(P=0.046) the possibility for LBP. With increase of BL-shift increases at 26%(P=0.024) DP. With increase of coronal trunk shift increases DP(P=0.011) and LBP(P=0.057). With increasing of sagittal loaded trunk shift increases LBP(P=0.065). In holidays: Girls suffer 3.2 times(P=0.050) more than boys in holidays; Asymmetrically carrying increases 8 times(P=0.006) back pain; Longer backpack carrying increases 2%(P=0.047) back pain; With shift of BL increases at 29.5%(P=0.042) back pain; With increase of coronal trunk shift increases 2.3 times(P=0.054) back pain. From high pain suffer: Girls suffer four times(P=0.015) more than boys; Asymmetrically backpack carrying increases four times(P=0.015) high pain; Increase of frontal trunk shift is associated by high pain three times (P=0.005) more.

Conclusion: Backpack carrying resulted in a forward lean of the upper trunk, and a decrease of cervical lordosis. Asymmetrically backpack carrying forced adolescents to rise the backpack bearing shoulder and simultaneously to shift the upper trunk contralaterally. These changes seem statistically to increase the incidence of back pain in the school period and during the holidays, particularly in girls. It is recommended that schoolchildren carry backpacks symmetrically with two straps.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 156 - 156
1 Mar 2006
Koureas G Petsinis G Zacharatos S Papazisis Z Korovessis P
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Purpose: Prospective randomized clinical and radiological study to compare the evolution of instrumented posterolateral lumbosacral fusion using either coralline hydroxyapatite(CHA), or iliac bone graft(IBG) in three comparable groups of patients.

Methods: 56 randomly selected adult patients with spinal stenosis were divided into three groups(A,B,C) included 17, 19 and 20 patients respectively and underwent decompression and fusion. The spines of Group A received IBG ; Group B IBG on the left side and CHA mixed with local bone and bone marrow on the right side; Group C CHA mixed with local bone and bone marrow bilaterally. The patients’s age was 61+11, 64+8 and 58+8 years for groups A, B and C respectively. SF-36, Oswestry Disability Index, and Roland-Morris surveys were used. Visual Analog pain Scale was used for pain. Roentgenograms (AP, lateral and oblique plus bending views) and CT-scans were used to evaluate the evolution of fusion. Two independent observers tested variability in evolution of the dorsolateral bony fusion 3 to 48 months postoperatively with the Christiansen’s and CHA resorption in Groups B and C.

Results: Intraobserver and interobserver agreement (r) for radiological fusion was 0.71 and 0.69 respectively, and 0.83 and 0.76 for evaluation of CHA resorption. There was no visible pseudarthrosis. Fusion was achieved one year postoperatively. CHA resorped 6 months postoperatively at the intertransverse spaces. Bone bridging started 3 months postoperatively in all levels posteriorly as well as between the transverse processes where IBG was applied. SF-36, Oswestry Disability Index, and Roland-Morris Score improved > 20 postoperatively in all groups. There was one pedicle screw breakage at the lowermost-instrumented level in group A and two in group C without pseudarthrosis. There was no deep infection. Operative time and blood loss were less in group C, while donor site complaints were observed in the patients of the groups A and B only.

Discussion & Conclusion: This study showed that autologous IBG remains the gold standard for posterior instrumented lumbar fusion to which each new graft should be compared. CHA was proven in this series not appropriate for intertransverse posterolateral fusion because the host bone in this area is little.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 253 - 253
1 Mar 2004
Korovessis P Repanti M Koureas G
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Aims: To investigate if coralline hydroxyapatite conduct bone formation in human spine. Methods: During revision surgery specimens were taken from the fusion mass from 13 patients, who received spinal instrumentation (Titanium alloy) and fusion with coralline hydroxyapatite. The age of patients at the time of revision surgery was 46±20 years. The time lapsed from the implantation of coralline hydroxyapatite (ProOsteon) was 11±11 months. The indication for revision was infection, pseudarthrosis, technical error, and pain related to hardware. The diagnosis for primary fusion was degenerative disease, spinal trauma and scoliosis. Coralline hydroxyapatite was applied on the posterior decorticated elements of the instrumented spine without any mixture with bone graft. Material from ten different places from the fusion mass was intraoperatively taken and the histological evaluation was made using the Hematoxylin-eosin histological stain. Results: There was a concentration of foreign-body like giant cells & development inflammatory granulomatous tissue around hydroxyapatite granules, which was gradually replaced by dense connective collagen tissue. Both inflammatory granulomatous and collagen tissue showed areas with foreign body reaction. In the cases, where bone has developed, the most initial finding was the presence of osteoblasts & apposition of osteoid in contact to hydroxyapatite granules. In a later phase, cancellous and lamellar bone has developed as a result of secondary ossification. Bone formation was observed in 11/15 cases. Conclusion: Coralline hydroxy-apatite conducts bone and osteoid formation around the implanted coralline hydroxyapatite granules in different areas of the human spine operated for different disorders.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 313 - 313
1 Mar 2004
Korovessis P Iliopoulos P Misiris A Koureas G
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Aims: Asymmetry of the breasts in female adolescents may be linked with right convex thoracic scoliosis. This is a prospective comparative study of the internal mammary artery (IMA) with Color Doppler Ultrasonography (CDU) in female adolescents and controls. Methods: 20 female adolescents with right thoracic scoliosis and 16 comparable individuals without spine deformity were included in this study. Scoliosis curve, vertebral rotation and concave and convex rib-vertebra-angle (RVA) at three vertebrae close to apical were measured. IMA- lumen, cross sectional area, time average mean ßow and ßow volume per minute were measured with CDU in scoliotics and controls. Results: The reliability of CDU. was high and the intraobserver variability low (ANOVA, P=0.92–0.94). There was no difference in CDU-parameters of IMA between right and left side, as well as between scoliotics and controls. In scoliotics the right IMA- time average mean velocity increases with both RVAs one level above the apical vertebrae (P< 0.01), convex RVA one level below the apical vertebra (P< 0.05), and concave RVA (P< 0.01). The left IMA-time average increases with only the convex RVA one level above the apical vertebra (P< 0.05). IMA- ßow volume increases with the convex RVA one level above the apical vertebra (P< 0.05), while the right IMA-ßow volume increases furthermore with the apical RVA (P< 0.01) and concave RVA one level above the apical vertebra (P< 0.01). The concave apical RVA (P< 0.01) and concave RVA one level above the apical vertebra (P< 0.01) increases with left IMA cross sectional area. Conclusion: This study showed that anatomy and haemodynamic ßow parameters of IMA signiþcantly correlated with apical roentgen-ographic parameters. However, there was no evidence for side-difference in vascularity of the anterior thorax wall that could justify the previous theories for development of right thoracic scoliosis in adolescent females


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_II | Pages 156 - 156
1 Feb 2004
Petsinis G Koureas G Repanti M Korovessis P
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Aim. The aim of this study is to estimate the medium-term results with the Zweymueller metal-on-metal THA in the osteoarthritis of the hip.

Material & Methods. A total of 266 consecutive patients, received 350 third-generation Zweymueller-SL total hip arthroplasties with metal-on-metal articulation for primary or secondary osteoarthritis. The age of the patients at the time of surgery was 55+9 years, (range 25–70 years). Seven (3%) patients did not return for their last follow-up evaluation and they excluded.

Results. The mean follow-up was 67 months (range 49–102 months). The preoperative Harris hip score was 45±19 and increased to 87±4 postoperatively. The invalidity of the patients was significantly improved postoperatively (p< 0.001). In all, 97% of the patients were satisfied or very satisfied with the result of the operation. There was no aseptic loosening noted in this series. Revision was done in 6 (1.8%) hips because of septic loosening (n=5, 1.5%) or technical error (n=1, 0.3%) during implantation. Dislocation of the prosthesis occurred in the early postoperative period in 2 (0.6%) hips because of technical errors during implantation. Periarticular ossification was observed in 30% of the hips (5% Brooker grades III and IV), but without associated disability. During revision surgery, no macroscopic metalosis could be identified in the newly formed hip joint membrane; how ever microscopic evidence for metalosis (Mirra grades 1 and 2) was seen in all revised hips. The survival for Zweymueller screw socket and stem 7.6 years after implantation was 99.4% and 96.8%, respectively.

Conclusion. The reasons of the loosening of Metal-on-Metal Zweymueller THA were the infection or the technical errors during implantation of the socket and nothing about the metal-on-metal articulation.


Previous investigations have postulated that the asymmetry of the breasts in female adolescents may be linked with the development of right convex thoracic scoliosis, although there is no correlation between breast asymmetry and curve type or scoliosis magnitude. This breast asymmetry is supposed to be linked with anatomic and functional asymmetry of the internal mammary artery that is the main supplier to the mammary gland. However, no measurements of anatomic and haemodynamic parameters of internal mammary artery have been made to justify or to reject the hypothesis of asymmetric blood flow volume to the breasts and costosternal junction in female adolescent scoliotics.

Twenty female adolescents with right thoracic scoliosis and 16 comparable female individuals without spine deformity were included in this study. Standing roentgenograms of the whole spine were made in all scoliotics to measure scoliosis curve, vertebral rotation and concave and convex rib-vertebra-angle at three vertebrae (apical, one level above and one below the apical vertebra). The Color Doppler Ultrasonography was used to measure at the origin of internal mammary artery its lumen diameter, cross sectional area, time average mean flow and flow volume per minute in scoliotics and controls and were compared each other. The roentgenographic parameters were compared with the ultrasonographic parameters in the scoliotics to disclose any relationship.

The reliability of color Doppler ultrasonography was high and the intraobserver variability low (ANOVA, P=0.92–0.94). There was no statistically significant difference in the ultrasonographic parameters of the internal mammary artery between right and left side in each individual as well as between scoliotics and controls. In scoliotics the right mammary artery time average mean velocity increases with the convex and concave rib-vertebra-angle one level above the apical vertebrae (P< 0.01), convex rib-vertebra angle one level below the apical vertebra (P< 0.05), and concave apical rib-vertebra angle (P< 0.01). The left internal mammary artery time average increases with only the convex rib-vertebra angle one level above the apical vertebra (P< 0.05). The right and left internal mammary artery flow volume increases with the convex rib-vertebra-angle one level above the apical vertebra (P< 0.05), while the right internal mammary artery flow volume increases furthermore with the apical concave rib-vertebra-angle (P< 0.01) and concave rib-vertebra angle one level above the apical vertebra (P< 0.01). The concave apical rib-vertebra-angle (P< 0.01) and concave rib-vertebra-angle one level above the apical vertebra (P< 0.01) increases with left internal mammary artery cross sectional area.

We concluded that anatomic and haemodynamic flow parameters measured at the origin of internal mammary artery are significantly correlated with apical rib-vertebra-angle in female adolescents suffering from right convex idiopathic thoracic scoliosis. This study did not find any evidence for side-difference in vascularity of the anterior thorax wall thus could not justify previous theories for development of right thoracic scoliosis in female adolescents.