Distal radius fractures (DRF) are a common injury in the A&E departments, being a major cause of disability of the upper extremity. The aim of this prospective study is to assess the possible association between objective physical variables such as wrist range of movement (ROM), radiological parameters, and upper extremity disability (measured by the DASH questionnaire), after conservative treatment of DRF. 44 patients with non-operatively managed DRF were enrolled in a prospective cohort study from July 2007 till September 2009. Inclusion criteria: unilateral DRF in skeletally mature patients, treated non-operatively with closed reduction and cast. Patients who sustained a previous fracture of the wrist, or bilateral wrist fracture, or with dementia, were excluded. After the closed reduction and inmovilization of the fracture in the A&E department we asked the patients to complete the DASH questionnaire, referring to their baseline pre-fracture state. All fractures were classified according to the AO classification. After one year, 36 patients were still available for follow-up purposes. We assesed the following objective physical variables: ROM of both wrists: flexion/extension arc and pronation/supination arch. We recorded the following radiologic parameters: radial angulation, volar angulation and radial shortening. The patient-perceived results were measured by the DASH questionnaire, while pain was measured using the VAS scale. Statistical analysis was performed using the SPSS 15.0.Introduction
Patients and methods
The amplitude was expressed as the amplitude at the experimental sde divided by the amplitude at the contralateral, untreated side, multiplied by 100%. Recording was done in gastrocnemius and tibialis anterior muscle.
The mean of intensity was 1.49 mA and the mean of threshold was 0,56 mA The mean of amplitude was 19,53mV for tibialis anterior and 42,83 mV for gastrocnemius The mean of latency was 2,28ms for tibialis anterior and 2,19ms for gastrocnemius Group B: (with PRP) The mean of intensity was 1,46 mA and the mean of threshold was 0,53 mA The mean of amplitude was 21,83mV for tibialis anterior and 19,32mV for gastrocnemius The mean of latency was 2,43ms for tibialis anterior and 2,29ms for gastrocnemius No stadistical difference on both groups was found. Histological studies were performed and results are no available at the moment of send this abstract
No evidence has been found that the use of PRP has a beneficial effect on peripheral nerve regeneration Further studies should be do to elucited the real role of PRP on peripheral nerve regeneration.