The remaining 144 patients were separated in to two groups. Group I (n=54) consisted of those patients that received one or more recorded I/A steroid injections in their operated knee in an orthopaedic clinic, rheumatology clinic or general practice setting prior to surgery. Group II (n=90) consisted of those patients with no record of receiving an I/A steroid injection prior to surgery.
In addition to those patients with confirmed deep infections, five patients underwent post-operative investigations for suspected deep infection, due to symptoms of persistent swelling or pain. All had received an I/A steroid injection pre-operatively. The length of time between injection and subsequent post-operative infection leads us to speculate that the steroid agent might not fully dissolve, becoming trapped within the soft tissues or cystic areas of degeneration in the knee joint. Such steroids may become re-activated during operation, leading to catastrophic results. Indeed, there is experimental evidence to suggest an increased risk of infection with the intra-operative administration of steroids.
A randomised controlled trial was performed to compare the clinical outcome for the two commonest types of anterior cruciate ligament (ACL) reconstruction. Methods: Patients undergoing elective anterior cruciate reconstruction were randomised into one of two groups. Group PT underwent reconstruction using a patella tendon autograft (n=14), whereas Group SG had a semitendinosus/gracilis autograft (n=18). The same surgeon performed all operations. IKDC self reported function and activity scores were recorded pre-operatively and at one and five years post operation. KT1000 values and muscle strength were recorded pre-operatively and one year post operation. Results: No significant difference between groups was found for any measurement at one year despite adequate study power. At five year follow up patients in the PT group had superior scores in every category of the IKDC self reported function score (mean IKDC score for PT group = 83, mean IKDC score for SG = 75). The activities of squatting and kneeling revealed the greatest difference between groups. It was found that 71% of patients in the PT group achieved IKDC scores of 80 or over whereas only 61% of patients in the SG group achieved 1 KDC scores of 80 or over.