There is no data concerning morphological dimensions of distal femur, proximal tibia and patella in Indian population. The objective was to analyse the anthropometric data in Indian knees and to co-relate them with existing knee arthroplasty systems. MRI scans of 25 patients (15 males &
10 females) who underwent bilateral knee scans for ligamental injuries were collected. Patients with arthritis, bone loss, varus/valgus deformity of >
15 degrees and those with immature skeleton were excluded. The mean age was 32 yrs (18–53 yrs). Three surgeons independently measured medio-lateral (ML), antero-posterior(AP) dimensions &
aspect ratio(AR) of distal femur, proximal tibia and unresected patellar thickness(PT) on three occasions one week apart to account for intra &
inter-observer variability. The resultant data of 50 knees was analysed using SPSS v14.0 and compared with five prosthesis knee systems (PFC sigma, NexGen, Scorpio, IB-II &
Gender specific knee). The mean ML &
AP for proximal tibia was 73.3±5.3 &
47.8±4.3 mm. The mean ML &
AP (lateral condyle) for distal femur was 74.3±5.9 &
65.4±5.0 mm. The mean PT was 24.7 &
21.8 mm in males &
females respectively. The ML &
AP showed a statistically significant positive correlation with the height of the person (ML r=0.55; AP r=0.50 &
p=0.01). The tibial and femoral AR showed higher ratio for smaller knees &
smaller ratio for larger knees i.e. decline in AR for increasing AP dimension. None of the prosthesis designs mimicked this decrease in AR and NexGen prosthesis infact showed an increase in AR. Gender differences in the morphological data were shown by variable tibial AR. Most of the available TKR prosthesis designs differ from actual knee morphometry of Indian population. These data provides the basis for designing optimal prosthesis for people of Indian/Asian origin in UK and overseas.