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Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 65 - 65
1 Mar 2009
Geerdink C Grimm B Vencken W Tonino A Heyligers I
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Introduction: Wear of the polyethylene (PE) acetabular component is widely regarded as the primary factor limiting the longevity of total hip arthroplasties (THA). To compare wear patterns of different polyethylene inserts computer assisted measurement techniques for in vivo polyethylene wear were developed. This study was performed to investigate which software out of four programs is most precise and easy to use in daily clinical practice.

Materials and Methods: 24 anteroposterior digital radiographs of patients with a THA (Stryker ABG-II with N2Vac and Duration PE inserts in metal backed cups) with an average of 8.0 years follow-up were measured twice by a blinded single observer for linear wear (head penetration) in a single image analysis. Four computer assisted wear measurement methods were compared, the commercially available Martell Hip Analysis suite 7.14 and Rogan Hyperview, a not yet available Rogan beta-version called View Pro-X and Roman v1.70, freely available software to download from the internet. While both Rogan software can read the DICOM format from the hospital image server, images had to be converted for Martell (greyscale TIFF only) and Roman (any format).

The annual wear rates were compared and intra-observer variability was calculated as the difference between both measurements (precision). The average time it takes to measure one image (without format conversions) was documented and practicality of daily clinical use was evaluated.

Results: The annual wear rates measured were (mean +/− SD): Martell=0.09+/−0.21,, Hyperview=0.14 +/−0.10, Pro-X=0.12+/−0.07 Roman=0.12 +/−0.06. Martell was the only method measured negative wear (7/24 cases).

The precision was (mean +/− SD): Martell = 1.74+/−1.53, Hyperview = 0.36 +/−0.92, Pro-X = 0.10+/−0.11 Roman = 0.08 +/−0.08.

The average measuring time per image was: Martell = 94s, Hyperview = 94s, Pro-X = 92s Roman = 158s.

Discussion: The Roman method is the most precise and easiest to use in daily practice, but takes the longest time to measure. The Rogan View Pro-X software is nearly as precise and easy to use but not on the market yet. It is an improvement over the Hyperview which looses precision by using a elliptical interpolation necessary for non-metal backed cups instead of circular interpolation which is more precise for metal backed cups. The Mar-tell method produced the intolerable low precision and in some cases “negative wear”. Only on large patient groups it may produce realistic average wear rates. We found out that the Martell edge detection method, originally developed for scanned analogue x-rays, functions inferiorly with digital images, the coming hospital standard. Image processing (smoothening) of the digital x-rays did increase accuracy and precision. We recommend the Roman software, a digital version of the Livermore method, for precision, ease of use and cost.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 129 - 129
1 Mar 2006
van der Wal B Tonino A Geerdink C Grimm B Heyligers I
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Introduction. Periprosthetic femoral fractures (PPF) have become more common as the population at risk, patients with joint arthroplasty, has increased. The choice of treatment depends on the location of the fracture relative to the implant, the residual fixation of the implant and patient factors such as deficient bone stock or osteopenia. The Vancouver classification categorises types of PPF and identifies strategies for its management. However, the Vancouver classification is mainly based and focused on cemented implants. Recently a modified algorithm for the management of PPF based on the Vancouver classification has been published. We analysed PPF with a single type of uncemented hip stem and compared our treatment to the most recent management algorithm.

Methods. From a consecutive series of 619 uncemented proximal hydroxyapatatite coated ABG-I prostheses, 14 patients (2.3%) sustained a PPF after an adequate trauma. The mean time between the index operation and the fracture was 6.9 years(range: 2.0 to 13.7 years). The mean age of the patients at the time of fracture was 79 years (range 59–87). The fracture patterns and state of stem fixation were analysed.

Results. In 5 patients the fracture was limited to the proximal Gruen zones 1 and 7 with the stem still firmly fixed (type A). Fracture treatment was conservative but in one patient the greater trochanter had to be reat-tached. Six B1,two B2 fractures and one B3 fracture were seen. Compared to the Vancouver classification we observed a different pattern in the type B fractures. No fractures at the tip of the stem were seen as common and characteristic in cemented implants. Three B1 fractures were operated due to fracture displacement and three were treated conservately. THe B2 and B3 fractures were managed with long uncemented revision stems because of a disrupted bone-prosthesis interface. Type C fractures were not seen. All fractures healed well.

Conclusion. The ABG-I shows a bone remodelling pattern consisting of mid stem bone condensation and proximal bone resorption, which leads to a high bone density gradient. This gradient acts as a stress riser and thus can be a preferred location for the initiation of a fracture. This pattern is distinctly different from the fracture types observed for cemented implants. . As a result the ABG-I stem was modified to the ABG-II design permitting more proximal and less mid-stem load transfer, smoothening the bone density gradient.

This study confirms that the Vancouver classification and the modified algorithm for the management of PPF are a simple,reproducible classification system also for the uncemented treatment modality. Conservative treatment is a valid option in case of a stable implant, while in case of a loose implant surgical intervention is mandatory.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 51 - 51
1 Mar 2006
Tonino A Geerdink C Grimm B Heyligers I
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Introduction: The Stryker ABG-I Total Hip Arthroplasty system with a Hydroxyapatite coated stem and cup has shown very promising short and mid-term clin-cial results at 2, 5 and 8 years. However, large discrepancies in component survival of the stem and cup have recently been published and require more data and further investigation about the potential causes.

Methods: All peer reviewed publications on the survival of the ABG-I hip prosthesis (9) were analysed regarding clinical results, polyethylene (PE) wear, osteolysis and survival. Own results from the first 250 consecutive ABG-I hips with a long-term follow-up of 10–15 years were added and compared.

Results: In the literature excellent survival rates of the ABG-I stem against osteolysis and aseptic loosening were reported with values ranging between 98%–100% after 5–10 years. In our own series stem survival against aseptic loosening was 100% at 10 years. No radiographic evidence of distal linear lysis was found around any stem. This was confirmed also in a histological investigation.

For the ABG-I cup the literature review gave survival rates between 59%–97% after 8–10 years. In our own study cup survival was 97.4% at 10 years. Looking at PE-wear, the literature gave average wear rates ranging from 0.24 to 0.32mm/year, values clearly above the wear rate boundary of 0.10–0.15mm/year usually considered as critical. In our own study augmented PE-wear (> 0.15mm/year) was noted in 23.6% of all implants. The majority (77%) of these implants were from patients younger than 70 years although this group only represented 57% of the total. The revision rates at 10 years reflect a similar trend with values much higher for patients below 70 years (2.8%) than above(4.9%).

Conclusions: Stem survival in our series was high, comparable to other published series and above the golden standard (cemented Charnley). However, the ABG-I cup showed lower survival rates, elevated PE-wear and augmented osteolysis around the holes. The comparatively high cup survival of our study is partly due to the high proportion of older patients. In the younger patient group PE-wear and revision rates were elevated. PE-wear is multifactorial and depends mainly on use. Some studies speculate it might be accelerated by low PE quality, crosslinking, liner fit or thickness. We found osteolysis not mainly at the rim but mostly around the 12 holes of the metal backed cup pointing at a possible pathway for wear particle migration into the reamed acetabulum as reported for other holed designs (Harris-Galante, Universal, Duraloc). As high wear and cyst formation did not always correlate it seems as if the pumping effect between flexing cup and acetabulum varies with component size, anatomy and bone quality influencing fluid flow, particle migration and osteolytic stimulus. A non-hole cup could alleviate this potential problem.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 45 - 45
1 Mar 2006
Geerdink C Tonino A Verburg A Rondhuis J Martell J Heyligers I Grimm B
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Introduction: In total hip arthroplasty (THA) polyethylene (PE) wear debris is major cause of osteolysis and aseptic implant loosening. Wear particle volumes must be reduced to increase implant survival. Various ways of crosslinking the molecular chains of PE have been proposed to increase the wear resistance of the bearing material but prospective long-term follow-up studies are scarce.

Materials & Methods A crosslinked PE acetabular insert was developed by gamma irradiating in a nitrogen atmosphere at a dose of 3MRad and subsequent annealing at 50° C for 144 hours to promote further crosslinking (“Duration” process). The Duration PE was compared to a conventionally prepared PE insert (irradiated at 3 MRad in air, no annealing) in a series of small punch tests, a hip wear simulator study and in-vivo as part of a randomized double-blind clinical study at three medical centers the PE-insert being the only variable. A total of 127 patients with 133 inserts (67 conventional, 66 Duration) were followed up between three and five years post-operatively. Wear was measured yearly by using a computer-based image analysis system. Radiographic appearance of potentially wear related phenomena such as osteolysis or loosening was assessed by an independent reviewer.

Results: Higher load at break during the small punch test confirmed the elevated crosslinking levels of Duration PE against the conventional PE. In the joint simulator Duration PE showed significantly lower volumetric wear rates (Mean SD: 21.7 2.3 mm3/10E6 cycles) than conventional PE (39.7 1.5 mm3/10E6 cycles, p< 0.05). A corresponding and significant level of wear reduction for the Duration PE was identified in-vivo (Duration: 43.7 33.6 mm3/year, conventional: 60.4 42.7 mm3/year, p=0.04). Radiographic analysis at the last follow-up gave evidence of femoral osteolytic lesions in five hips with conventional PE inserts and only one hip with a Duration insert.

Conclusions: Acetabular inserts made of crosslinked PE using the Duration process can significantly reduce in-vivo wear rates and the occurrence of potentially wear related osteolytic effects in the long-term follow-up of THA patients. The reduced clinical wear rates corresponded well with the results from the wear simulator measurements. This suggests that a PE with further increased crosslinking which shows even lower wear rates in simulator studies will lead to even lower wear and associated osteolysis in long-term clinical application.