The rate of infections in primary and revision surgery (hip and knee) The success rate in treating those infections Long term survival rate of revision arthroplasties
Considering an infection free arthroplasty as the goal, the overall success rate of treatment was under 48% (30/69). The success of treating infections with debridement and retention of components was even lower (29%). Further analysis revealed a higher success of this approach (45%) when considering more appropriate candidates (short term infections). An interesting statistically significant difference was found favoring this approach in the knee. Two-stage revision strategy was successful in achieving revision arthroplasty in 43% (20/46) of the cases. Most patients were never considered candidates to the second stage procedure. Knee joint and resistant microorganisms were found to be predictors of bad prognosis. There was a 90% (18/20) survival rate of revision arthroplasties after two years average follow-up. There were only 2 cases of relapsing infection both controlled without prosthetic removal.
Chondrosarcoma is the second most frequent primary malignant tumour of bone, representing approximately 25% of all primary osseous neoplasms. Chondrosarcomas are a group of tumours with highly diverse features and behavior patterns, ranging from slow-growing non-metastasizing lesions to highly aggressive metastasizing sarcomas. As radio and quimio-resistant tumours, the surgery constitutes the unique chance of cure. Nowadays, besides the curative intention, the reconstructive surgery is also a priority in order to save the limb and optimize the function. This case report is about a young woman, of 24 years old, with hip-related pain and a large mass in the left pelvis. The imagiologic study showed a large mass of about 8 cm of large diameter, starting at the anterior wall of the acetabulum, involving the pubic arcs and with matrix calcification. The core needle biopsy confirmed the presence of a chondrosarcoma, staged as a IIB of Enneking. Because of its size and localization the limb salvage surgery has been a challenge. The surgery included a broad approach of the left hemipelvis, with wide excision of the tumour, reconstruction of the abdominal wall with a propylene prothesis and reconstruction of the hemipelvis with a “custom-made” prothesis with preservation of the femoral neurovascular bundle. The patient started to walk with total bearing after three months and had a normal gait and a nearly normal life during eleven months. Fifteen months after the surgery lung metastasis and local recurrence were diagnosed and she died six months after.
We present the results of 412 core needle biopsies guided with fluoroscopy, CT and echo scan with assessment of accuracy and costs From January/96 to December/08, 56 soft tissue and 356 bone tumours and tumour-like lesions were submitted to this technique in the Oncology Unit of Hospital Santo Antònio. All biopsies were performed by the same team (one radiologist, one orthopaedic surgeon) and the histological exam by the same pathologist. There were 77 cases in which diagnosis was inconclusive (sample not representative, crushing, necrosis, hemorrhagic features or image/histological dissociation); 36 of these were soft tissue and 41 bone lesions. histiocytic elements, 65 metastases, 8 recurrent malignancies, 5 osteomyelitis and 2 metabolic diseases. Diagnosis was confirmed in 278 cases with the definitive surgery and only one was wrong. The other 57 cases were later controlled by imaging exams and there were no reasons to suspect a wrong diagnosis. No complications occurred. Costs were estimated to be less than one fifth of an open biopsy. The high accuracy (only one case was misdiagnosis), the safety, the costs and the fact that in only 18,7% the diagnosis was not established make us consider this method effective and to be encouraged. Better selection of lesions and more attention to directions of the cores may low the number of inconclusive diagnosis.
Synovial cell sarcoma is one of the most common soft tissue tumours. Prognosis of this tumour is related to initial care. Survival rates have improved in the past 20 years because of treatment with primary radical surgery, along with chemotherapy and radiation. This case report is about a woman, of 68 years old, with a left shoulder-related pain and mass with about four months. The image study showed a lobulated and irregular mass, with about 12x10x9cm, infiltrating the rotator cuff and glenohumeral joint. The core needle biopsy confirmed the presence of a synovial sarcoma, staged as a T2N0M0. The treatment started with neo-adjuvant chemotherapy, with a poor response. Then, surgery was performed, with a wide excision of the scapula, proximal humerus and clavicle (type IV of Malawer) without reconstruction. The treatment regime ended with the radiotherapy. Eighteen months after the surgery the patient remains disease-free and a neo-joint is starting to form. At this time the DASH score was 63.8. Despite the flail shoulder function is acceptable.
Osteosarcoma is the most common tumor among the primitive malignant bone tumors. When different features of these lesions are considered, we can find several varieties of this tumor, with distinct anatomo-clinical presentation, treatment and prognosis. Until the 70s, its prognosis was very poor, the standard surgical treatment was amputation and 80% of the patients died from metastatic disease. With the development of new surgical techniques, the advent of combined chemotherapy and more accurate imaging, the outcome of these patients has improved significantly. Consequently, approximately 90% of the surgical cases are treated with limb salvage procedures. The authors reviewed 22 cases of Osteosarcoma treated in HGSA, 20 being submitted to the T20 Rosen protocol. Trocar biopsy was performed in 19 of the patients and 3 of the patients were submitted to incisional biopsy in order to complete diagnosis. Regarding the anatomo-clinical pattern, Classic Osteosarcoma was present in 19 patients, 2 of the cases were Parosteal and 1 was Central low-grade Osteosarcoma. The majority of patients underwent limb salvage surgery; only 2 had amputation surgery and 1 patient was submitted to palliative chemotherapy. Considering limb salvage procedures, several techniques were performed: arthrodesis (n=1), grafts (n=4), prosthesis (n=13) and compound prosthesis (n=1). The resection margins were wide in 19 cases, marginal in 2 cases and in 1 case intra-luminal. Among the treated patients: 12 patients are still alive and cured, 3 have metastatic disease, 6 are deceased and 1 didn’t complete the follow-up. The final functional score obtained was 84% for the superior limb (DASH) and 81% for the inferior limb (TESS). Although the scarce number of cases described were not enough to make any kind of correlation, it was possible to establish the accuracy of the multidisciplinary approach involved both in the diagnosis and treatment, in agreement with the “state of art”.
Osteoid osteomas are benign, painful osteogenic tumours of small size (≤ 1,5 cm). Surgical resection of the nidus has been the elected method of treatment for decades but some complications and difficulties (poor localization, extensive tissue damage, fractures, delayed recovery) encouraged the development of less invasive techniques such as radiofrequency. Lack of histological proof is the major concern regarding radiofrequency ablation as we make the diagnosis by the clinical findings and the image features. We present the results of 20 patients with osteoid osteoma treated with radiofrequency from January 2004 to December 2008 (mean follow up 23 months). All patients were under general anaesthesia and de access route was chosen in the CT-suite. 11 cases were located in the proximal femur (head, neck and subtrocanteric region), 2 in the distal femur, 2 in de distal humerus, 2 in the tibia, 2 in the acetabulum, and 1 in de vertebal body of D8. In all cases we used a Cool-tip TM RF electrode (water-cooled tip) reaching a heating temperature of 42°C to 48°C during 12 minutes. In 7 patients a cannulated drill bit was used to penetrate the thick cortical or to reach the nidus through the opposite side in order to avoid a neurovascular bundle. Hospital discharge was allowed after 6 to 8 hours after the procedure. No complications occurred. All patients, except one, experienced complete relief of the pain although the 6-month follow-up CT’s do not show sclerosis of the nidus. None of them recurred till data. The patient who did not recover had not had a clear diagnosis. We conclude that radiofrequency ablation is effective, safe, favouring rapid recovery and, of course, reduces economical and social costs.
Intramuscular hemangyomas are benign tumours (0,8% of all hemangyomas). Their aetiology is uncertain but they are possibly congenital, although some seem to be related to trauma. Symptoms (usually pain and swelling) may be present for years. Histological subtypes are cavernous, capillary and mixed. Optimal management includes precise diagnosis and wide excision to prevent local recurrence. Authors present a case of a 79 years male with cavernous hemangyoma of the thigh with three years of evolution. The tumour eroded the femur and the patient had a mass all over the thigh with tension and pain. Diagnosis was suspected by phleboliths seen on x-ray and MRI and was confirmed by open biopsy. Treatment was a complete excision with double approach, medial and lateral, plus prophylactic nailing of the femur. With a four years follow – up, the patient has no sign of recurrence and has a normal function of the inferior limb and a normal gait.