Large and massive rotator cuff tears can cause persistent pain and significant disability. These tears are often chronic with substantial degeneration of the involved tendons. Surgical treatment is challenging and the functional outcome after repair less predictable then for smaller tears. The aim of this study was to determine the functional outcome and rate of re-rupture after mini-open repair of symptomatic large and massive rotator cuff tears using a modified two-row technique.

Twenty-four patients, who were operated on under the care of a single surgeon between 2003 and 2006, were included in this study. Patients were assessed prospectively before and at a mean of 27 months after surgery using Constant Score and Oxford Shoulder Score. This assessment was carried out by an independent physiotherapist specialising in shoulder rehabilitation. At follow-up an ultrasound was carried out by a musculoskeletal radiographer to determine the integrity of the rotator cuff repair. Patient satisfaction was assessed using a simple questionnaire.

The mean Constant Score improved significantly from 36 preoperatively to 68 postoperatively (p< 0.0001), the mean Oxford Shoulder Score from 39 to 20 (p< 0.0001). Four patients (16.7%) had a re-rupture diagnosed by ultrasound. 87.5% of patients were satisfied with the outcome of their surgery. Tear size and repair integrity did not significantly influence functional outcome. 87.5% of patients were satisfied or very satisfied with the outcome of their surgery.

This study shows that the two-row repair of large and massive rotator cuff tears using a mini-open approach is an effective method of repair with a comparatively low re-rupture rate. It significantly improves the functional outcome and leads to a very high patient satisfaction. We conclude that these results justify repair of large to massive rotator cuff tears when possible, irrespective of chronicity of symptoms.

Introduction: Scoring systems for assessment of shoulder function are invaluable tools in determining changes in a patient’s condition. We utilised two commonly used assessment tools in patients with conservatively treated proximal humeral fractures to establish their behaviour in this patient group.

Methods: OSS and Constant Scores were collected prospectively at 3 and 12 months post injury, for 103 consecutive patients treated conservatively for proximal humeral fractures. Comparison of the scores was undertaken by creating scattergraphs, calculating Pearson’s correlation coefficient and producing Bland and Altman plots. Sensitivity to change was calculated using paired t-tests. Linear regression analysis was finally performed to predict Constant Score from the OSS.

Results: 177 sets of scores were collected. The scores correlated well with a correlation coefficient (r) of 0.84 (p< 0.001,n=177). This relationship was equally strong at 3 (r=0.77 (p< 0.001,n=94)) and 12 months (r=0.87 (p< 0.001,n=83)) and demonstrated a clear relationship between the scoring systems. Bland and Altman plots showed good agreement between the scores. Both scores were sensitive to change over time (OSS (t(81)=6.14,p< 0.001), Constant (t(80)=−10.27,p< 0.001)). Regression analysis produced a regression equation (R2=0.70) of: Constant Score=99.3-(1.67 times OSS). This level of model fit was statistically significant (F(1,175)=412.8,(p< 0.001))

Conclusion: This study provides information about the behaviour of two frequently used functional scoring systems in patients with proximal humeral fractures. Based on our finding we feel that these scores are appropriate assessment tools in these patients. The OSS may also be considered as an alternative for assessing longer term follow up as, being solely subjective, it is easier to administer and correlates well with the Constant Score.

To investigate whether the harvesting of Hamstring graft in ACL reconstruction results in compromised knee flexion strength and proprioception, and hence knee function?, a prospective study, approved by the local Ethics Committee, to assess the function and strength of the knee joint in patients who had ACL reconstruction done using a four-strand Hamstring graft. The control group was the contra lateral knees. 28 knee joints were studied with mean follow-up of 70.1 weeks (52–156). All operated knees received an extensive set regime of pre-and post-operative physiotherapy. Assessment tools were clinical examination, Laxometer arthrometry for measured anterior draw, Biodex dynamometry and Stabilometry for Hamstring and quadriceps strength and proprioception. The knee function was assessed using a questionnaire incorporating IKDC (International knee documentation committee) performa, Lysholm 2 score, Tegner’s activity scale and Oxford knee score.

Following reconstruction (mean 70.1 weeks postop), objective assessment using Biodex dynamometer showed that mean peak flexion torque around the knee joint was 69.8 N-m and 76.2 N-m in the operated and non-operated knee respectively. There was no difference in flexion torque in both groups. Mean Flexion: Extension ratio around the knee joint was 53.9% in the operated and 53.2% in non-operated sides. Mean stability index, measured using open eye stabilometry, was 3.5 (SD 2.4) in the operated side and 3.1 (SD1.8) in the non-operated side, with no significant difference demonstrable (p< 0.05).

The mean age of patients was 28.3 years (18–44). Mean IKDC score following reconstruction was 74.8 (49–100), SD18.5. Mean Tegner’s activity scale improved from 2.5(3–7) pre-operative to post-operative 5.4(3–7), p< 0.01. Mean Lysholm 2 score improved from 53.4(41–76) pre-operatively to 85(64–100) post-operatively, p< 0.01. Subjective function of the knee on a scale of 0–10 improved from pre-operative 3.1 to post-operative 7.7 (p< 0.01). Arthrometry at 25-degree flexion and 130 N force using Laxometer showed mean anterior laxity 5.3mm on the operated side and 3.1 on the healthy side (side to side difference 2.2mm).

Conclusion: The function of the knee improved significantly following ACL reconstruction both objectively and subjectively. The harvesting of Hamstring as a graft neither compromises the flexion torque nor the proprioception around the knee joint.

To evaluate blood transfusion practice in hip and knee arthroplasty, the development of evidence based guidelines, their implementation and prospective analysis of change. An audit was carried out in 4 stages to complete the loop. Stage 1: Retrospective analysis of blood transfusion practice in primary and revision hip and knee arthroplasty. Review of case notes, nursing record, anaesthetic sheet and pathology results from a computer database was carried out. Rates of transfusion, patients’ body weight and height, peri-and post-operative blood loss, use of anticoagulants, drains, surgical approach, type of implant and cement, grade of surgeon and anaesthetist and haemodynamic complications were recorded. Stage 2: Literature search to develop evidence based guidelines for blood transfusion.

The data in stage 1 was evaluated in the light of those guidelines to determine appropriateness of blood transfusion. Stage 3: Dissemination and implementation of guidelines. Anaesthetic, Orthopaedic and audit departments were involved. Guidelines were presented, discussed, finalised and circulated.

Stage 4: Prospective re-evaluation of blood transfusion practice was undertaken. Parameters as in stage 1 plus documentation of reason for blood transfusion by the prescriber were recorded.

For stage 1, 97 Hip arthroplasty (86 primary and 11 revisions) and 119 Total knee arthroplasty procedures (109 primary and 10 revisions) over a period of 26 weeks were studied. Blood transfusion rate was 50.5% (49/97) in hip arthroplasty and 28.5% (34/119) in knee arthroplasty. Evidence based guidelines were developed. 55% transfusions were thought to be inappropriate in the light of guidelines. Following completion of stage 2 and 3, prospective audit of blood transfusion practice was initiated. It was compulsory for the person prescribing blood to document the indication. Data was collected on a daily basis for 15 weeks. In that period 150 joint replacements were undertaken. 77 hip arthroplasty (71 primary and 6 revisions) and 73 knee arthroplasty procedures (66 primary and 7 revisions) were undertaken. Blood transfusion rates for hip arthroplasty decreased to 18% (14/77) and for knee arthroplasty to 5.4% (4/73).

Overall transfusion rates decreased from 83/216 (38.5%) to 18/150 (12%) after implementation of guidelines. This represents an overall reduction of 68%.

Conclusion: A multidisciplinary approach and putting evidence based practice in place has resulted in reduced blood transfusion rates in hip and knee arthroplasty in our institution. We feel this change is an example of implementation of evidence-based practice.

Background: The incidence of proximal humeral fractures is increasing with time. There is continuing debate about the indications for surgical intervention for this relatively common injury. Baseline data on functional outcome is essential in order to study the effect of surgical intervention. Functional outcome scores provide reliable and valid judgments of health status and the benefits of treatment. During our preparation of a study proposal on this topic to the Health Technology Assessment Program recently, we noted the lack of such data on outcome scores in the current literature.

Aim: To assess the functional outcome using the Constant and Oxford scores in patients treated conservatively for proximal humeral fractures.

Methods: We prospectively studied 103 consecutive patients who were treated conservatively for proximal humeral fractures. Patient demographics, fracture type (Neer), hand dominance and comorbidity were recorded. Constant and Oxford shoulder scores were recorded 3 and 12 months post injury.

Results: The average Constant shoulder score for males was significantly higher (better outcome) and the Oxford shoulder score significantly lower (better outcome) as compared to females. The scores were not affected by hand dominance. Although the raw scores tended to be worse with 3 or 4 part fractures the difference in the mean scores between the various Neer fracture types did not reach convential levels of significance.

A trend towards lesser degrees of improvement in the outcome scores was noted with increasing age. The degree of improvement in the outcome scores was not affected by sex, limb dominance or fracture type (Neer’s classification).

Conclusion: This study indicates the average behaviour of the Constant and Oxford scores with conservative treatment of proximal humeral fractures. This data should help with sample size and power calculations when studying interventions for this injury. We hope that this data will provide a baseline to help inform future study designs on proximal humeral fractures.

Introduction and Aims: To determine if the surface area of partial thickness (< 50%), Bursal side tears of the cuff influence outcome following Subacromial Decompression.

Method: Shoulder function using Constant score (CS) was recorded before and a minimum of one year after Arthroscopic Subacromial Decompression (ASD) in patients undergoing surgery for primary impingement. In patients who had partial thickness, Bursal side tears (BT), the length of the tear in its largest dimension (surface area) was measured. These patients were divided into two groups according to the tear surface area (≤9 mm and ≥10mm) .To determine whether having a BT (< 50% thickness) or its surface area affect pre- and post-operative CS, t-tests were performed.

Results: 110 patients underwent ASD over a one-year period for primary impingement. Twenty-two patients with partial thickness BT and 18 patients with intact rotator cuff were included in this study. In 10 patients, the BT was ≤9 mm (mean 7 mm) and in 12 patients BT was ≥10mm (mean 13 mm).

Statistical analysis of pre- and post-operative Constant scores showed that, in ≤9 mm group CS increased significantly by 21.5, p=0.02, 95% CI (4.9, 38.1). CS increased in ≥10mm group by 22.8, p< 0.01, 95%(11.5, 34.1). Comparing the change in CS between these two groups with different tears size, there was no significant difference (2-sample t-test, t=0.15, 20df, p=0.88).

To determine whether having BT tear affects pre- and post-operative Constant scores, all BTs were grouped together and compared with the group of patients with intact cuff.

In the group with BTs, average Constant scores increased significantly (paired t-test, t=5.24, 21df, p< 0.01) by 22.2 with 95% CI (13.4, 31.0).

In the group with no tears, average Constant scores increased significantly (paired t-test, t=5.17, 17df, p< 0.01) by 26.6, 95% CI (15.8, 37.5).

Comparing the levels of absolute change in Constant scores from pre- to post-operation between the two groups there is no difference in outcome between patients with a tear and those without a tear (2-sample t-test, t=1.03, 38df, p=0.31).

Conclusion: We conclude that ASD yields satisfactory results in patients with BTs involving < 50% thickness, irrespective of the surface area of the tear.

Systematic studies are required to examine the effects on outcomes of alternative treatments and surgical techniques in the management of Orthopaedic conditions. Functional outcome scores provide reliable and valid judgments of health status and benefits of the treatment. We undertook a prospective study to assess the functional outcome in patients treated conservatively for proximal humeral fractures.

103 patients treated conservatively for a proximal humeral fracture were followed prospectively. Constant shoulder score and Oxford shoulder score were recorded at 3 months and 12 months follow-up.

A trend towards lesser degrees of improvement in the outcome scores was noted with increasing age. The degree of improvement in the outcome scores was not affected by sex, limb dominance or fracture type (Neer’s classification).

This information gives a guide to average behaviour in different groups of individuals with conservative treatment for proximal humeral fractures. We could then using this data postulate what would constitute a clinically relevant difference and calculate study numbers required while assessing other form of treatments for such fractures

Aims: Whether the harvesting of Hamstring graft for ACL reconstruction results in compromised knee flexion strength and proprioception, and hence knee function?

Methods: A prospective study, approved by the local Ethics committee, was undertaken to assess the function and strength of the knee joint in patients who had ACL reconstruction performed using a four-strand Hamstring graft. The contra lateral knee acted as control. 28 knee joints were studied with mean follow up 70.1 weeks (range 52–156). All operated knees received an extensive set regime of pre and post-operative physiotherapy. Assessment tools were Biodex dynamometry and stabilometery for hamstring and quadriceps strength and proprioception, clinical examination, Laxometer arthrometry for measured anterior draw. The knee function was assessed using a questionnaire incorporating International knee documentation committee (IKDC) proforma, Lysholm 2 score and Tegner’s activity scale.

Results: Objective assessment using Biodex dynamometer pre-operatively showed that mean peak flexion torque was 67.86 N-m (SD± 24) in the involved knee and 76.1 N-m (SD± 22.2) in the healthy knee. Following reconstruction (mean 70.1 weeks post-op), mean peak flexion torque around the knee joint was 69.8 N-m (SD± 20.6) and 76.2 N-m (SD ±22.1) in the operated and non-operated knee (control) respectively. Flexion torque in the operated knee was as good as the control and not significantly different from the pre-operative levels.

Mean Flexion: Extension ratio around the knee joint was 53.9% in the operated and 53.2% in non-operated sides. Mean stability index, measured using open eye stabilometery, was 3.5 (SD±2.4) on the operated and 3.1 (SD±1.8) on the non-operated side, with no significant difference demonstrable.

The mean age of patients was 28.3 (range 18–44) years. Mean IKDC score following reconstruction was 74.8 (range 49–100), SD±18.5. There was significant improvement in pre and post reconstruction mean Lysholm 2 and Tegner’s activity scores (p< 0.01). Subjective function of the knee on a scale of 0–10 improved from pre-operative 3.1 to post-operative 7.7 (p< 0.01). Arthrometry at 25-degree flexion and 130 N force using Laxometer showed mean anterior laxity 5.3mm on the operated side and 3.1 on the healthy side (side to side difference 2.2mm).

Conclusion: The function of the knee improved significantly following ACL reconstruction both objectively and subjectively. The harvesting of Hamstring as a graft neither compromises the flexion torque nor the proprioception around the knee joint.

Aims: To ascertain the efficacy of viscosupplementation with Supartz intra-articular knee injections when used in the absence of a specific protocol for its use.

Methods: Retrospective cohort study using data from a dedicated injection clinic, patient case notes and knee radiographs. Patients received the therapy in the absence of a protocol for its use. Patient’s age, gender, symptoms, walking ability, presence of deformity, medication history, previous injection or surgical intervention, physiotherapy, co-morbidity, date of presentation, delivery of course of supartz injections and indication were recorded. Knee radiographs were analysed using Kellgren and Lawrence grading system. Pain relief and avoidance of surgical intervention (when surgery was an option) were the outcome measures.

Results: 965 intra-articular injections in 193 courses of supartz therapy were given in 143 patients. 45.6% were male and 54.4% were female patients. At presentation, 33.2% patients were able to walk < 1/2 a mile, 35.2% patients 1/2-1 mile and 31.6% > 1 mile. Radiological assessment (using Kellgren and Lawrence grading) showed 2 cases with stage 1 disease, 83(43%) with stage 2, 102(52.3%) with stage 3, and 6 cases with stage 4 disease. The medial compartment was involved in 185 cases (95.9%), the lateral compartment in 44 (22.8 %) and patellofemoral joint (PFJ) was involved in 122 (63.2 %).

Pain relief was obtained in 84/193 cases (43.5%). In 122 cases where the aim was to avoid surgery, this was achieved in 52 cases (42.6%). Success rate decreased with increasing severity of disease (Fisher’s Exact test; p< 0.01). Only 25/122 cases with PFJ involvement had pain relief (21%), compared to 59/71 cases without PFJ involvement (83%), (Chi squared test; χ 2(1)=71.57, p< 0.01). Younger age (< 60 years) is a poor prognostic factor (Chi squared test; χ2(1)= 5.86, p=0.02).

Conclusions: Younger patients and those with PFJ involvement and advanced disease are unlikely to benefit from Supartz intra-articular injection. We consider it inappropriate to use this therapy in the absence of a protocol for its use.

Aims: Does PHILOS (Proximal Humeral Internal Locking system) construct provides better þxation than Clover leaf plate and T-plate in a simulated 2-part fracture of proximal humerus, in an osteoporotic bone model?Materials and Methods: Biomechanical laboratory study. Third generation composite Humerus model was used, with short e-glass epoxy þbres forming cortex and polyurethane cancellous core. Low density polyure-thane core (1.2gm/cc) was used to simulate an osteoporotic model. Osteotomy at surgical neck of humerus was carried out to create 2-part fracture of proximal humerus. Samples were randomised to receive one of the implants. Following þxation samples were placed in a custom made jig to þx proximal and distal ends without interfering with implants and osteotomy site. All samples were subjected to cyclical torque, Torque to failure, Cyclical compression and Compression loading to failure. Results were entered in a database. Results: PHILOS provided signiþcantly better þxation in ÔTorque to failureñ experiment. PHILOS construct shows less plastic deformation in cyclical torque and cyclical compression. Locking screws did not Ôback offñ in any of the experiments involving PHILOS construct, however ordinary screws did back off both in Ôtoque and compressionñ testing. Conclusions: PHILOS construct provides better stability in Torque and compression as compared to conventional plating devices, in an osteoporotic bone model.

Aims: To derive a formula for blood loss estimation and also to assess if high body weight is protective against blood transfusion following elective arthroplasty? Methods: Retrospective study of patients undergoing elective primary hip arthroplasty. Weight of the patient, pre and postoperative haematological investigations and details of blood transfusion were collected. Results: Formula for blood loss estimation was derived, Blood loss= ( 70 x body weight in Kg) x (drop in haematocrit) (Pre-op haematocrit+ post-op haematocrit)Ö2

The mean blood loss in 86 patients was 1631ml. Mean blood lost/Kg body weight was 22.6ml. 36/86 patients had < 21ml/kg (42%) and 50/86 had > 21ml/kg blood loss (58%). 21 ml/kg represents 30% loss of blood volume. Patients losing > 21ml/kg blood had signiþcantly higher blood transfusion rates (Chi squared test; χ2(1)= 5.50, p=0.02).

The amount of blood loss increases with weight of patients (p< 0.01). The rates of transfusion in patients with ≤ 72 kg weight (circulatory volume ~ 5 litre) was 51% (23/45), and in patients > 72 kg it was 36.5% (15/41). Rates of transfusion were related to pre-op Hb but were unaffected by gender, age, cemented/uncemented prosthesis, surgical approach, type of prosthesis, use of drains, grade of surgeon, type of anaesthetic. Conclusion: Calculated blood loss > 21ml/kg and patientñs low body weight are associated with increased risk of blood transfusion.

To determine if the surface area of partial thickness (< 50%), Bursal side tears of the cuff influence outcome following Subacromial Decompression.

Shoulder function using Constant score (CS) was recorded before and a minimum of one year after Arthroscopic Subacromial Decompression (ASD) in patients undergoing surgery for primary impingement. In patients who had partial thickness, Bursal side tears (BT), the length of the tear in its largest dimension (surface area) was measured. These patients were divided into two groups according to the tear surface area (≤9 mm and ≥10mm) .To determine whether having a BT (< 50% thickness) or its surface area affect pre and postoperative CS, t-tests were performed.

110 patients underwent ASD over a one-year period for primary impingement. 22 patients with partial thickness BT and18 patients with intact rotator cuff were included in this study. In 10 patients, the BTwas ≤9 mm (mean7mm) and in 12 patients BTwas ≥10mm(mean13mm). Statistical analysis of Pre-& postoperative Constant scores showed that, in ≤9 mm group CS increased significantly by 21.5, p=0.02, 95% CI (4.9, 38.1). CS increased in ≥10mm group by 22.8, p< 0.01, 95%(11.5, 34.1). Comparing the change in CS between these two groups with different tears size, there was no significant difference (2-sample t-test, t=0.15, 20df, p=0.88).

To determine whether having BT tear affects pre- and post-operative Constant scores, all BTs were grouped together and compared with the group of patients with intact cuff.

In the group with BTs, average Constant scores increased significantly (paired t-test,t=5.24,21df,p< 0.01) by 22.2 with 95% CI (13.4, 31.0). In the group with no tears, average Constant scores increased significantly (paired t-test,t=5.17,17df,p< 0.01) by 26.6, 95% CI (15.8, 37.5).

Comparing the levels of absolute change in Constant scores from pre- to post-operation between the two groups there is no difference in outcome between patients with a tear and those without a tear (2-sample t-test, t=1.03, 38df, p=0.31).

We conclude that ASD yields satisfactory results in patients with BTs involving < 50% thickness, irrespective of the surface area of the tear.

The Department of Health and the Public Health Laboratory Service established the Nosocomial Infection National Surveillance Scheme (NINSS) in response to the need to standardise the collection of information about infections acquired in hospital. This would provide national data that could be used as a ‘benchmark’ by hospitals to measure their own performance. The definition of superficial incisional infection (skin and subcutaneous tissue), set by Centers of Disease Control (CDC), should meet at least one of the following criteria: I: Purulent drainage from the superficial incision. II: The superficial incision yields organisms from the culture of aseptically aspirated fluid or tissue, or from a swab, and pus cells are present. III: At least two of the following symptoms and signs of inflammation: pain or tenderness, localized swelling, redness or heat, and a. the superficial incision is deliberately opened by a surgeon to manage the infection, unless the incision is culture-negative or b. clinician’s diagnosis of superficial incisional infection.

This study assessed the interobserver reliability of the superficial incisional infection criteria, set by the CDC, in current practice.

The incisional site of 50 consecutive patients, who underwent elective primary joint arthroplasty (Hips & Knees), were evaluated independently by four observers. The most significant results of the study I: All four observers achieved absolute agreement (kappa=1) for Purulent wound discharge and clinical diagnosis of wound infection. II: The four observers obtained good agreement for pain criteria (kappa=0.76, III: There was significant disagreement (fair to poor) between all four observers for the following criteria: Localized swelling (kappa=0.34), Redness (kappa=0.33) and tenderness (kappa = 0.05).

This is the first study to assess the reliability of the criteria, as set by the CDC and recommended by NINSS, for the diagnosis of superficial incisional infection and shows the Criterion III is not reliable and we recommend it should be revised. Failure to do so could lead to inaccurate statistics regarding hospital wound infection and detrimental effect on hospital trusts in the setting of league table.