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Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 143 - 143
1 Mar 2008
Daniels T Duggal N Redekop S Yeung M
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Purpose: 1/ To compare patients treated with both ankle arthroplasty or ankle fusion using validated functional outcome measures and a computerized motion analysis system that measures three-dimensional kinematics and temporal data. 2/ To compare the functional outcome and gait mechanics of ankle arthroplasty and ankle arthrodesis to a healthy control group.

Methods: Fifteen patients underwent seventeen ankle arthroplasties with the Scandinavian Total Ankle Replacement (STAR), twenty-three patients underwent ankle arthrodesis, and twenty-three healthy control patients were enrolled in this study. Assessment included: 1/ Ankle Osteoarthritis Scale (AOS) and general health status (SF-36). 2/ Gait data, including temporal-spatial, kinematic, and kinetic parameters using a seven-camera VICON 370 system (Oxford Metrics, UK). Comparison between groups was done using one-way ANOVA post hoc Bonferroni (p< 0.05).

Results: Kinematic gait parameters for post-op arthrodesis, post-op arthroplasty and a control group are summarized in Table 1. Postoperative arthrodesis patients had significantly reduced ankle range of motion in the sagittal and frontal plane when compared to both postoperative arthroplasty patients and a control group (p< 0.05). Forefoot range of motion was also significantly reduced in the sagittal and frontal planes for arthrodesis patients when compared to the control group, however there were no significant differences between patient groups or between arthroplasty patients and controls (p< 0.05).|Functional questionnaire (AOS) data for the three groups is summarized in Table 2. There were no significant differences in patient perception of pain and disability, however AOS scores compared between arthrodesis patients and a control group were significant (p< 0.05). No difference was noted in AOS scores between ankle arthroplasty and control patients at one year post operative.

Conclusions: Functional outcome analysis of treatment methods of end-stage ankle arthritis clearly shows the advantage of ankle arthroplasty over arthrodesis when comparing kinematic and outcome questionnaire data against controls. The results of this study will help determine the best surgical treatment for patients with end-stage ankle arthritis failing non-operative treatment.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 411 - 411
1 Sep 2005
Sears W Sekhon L Duggal N McCombe P Williamson O
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Introduction The early clinical results of cervical disc replacement surgery are encouraging but the in vivo kinematics of prostheses remains poorly understood. Two recent published reports suggest that use of a prosthesis with an unconstrained (over normal range of motion) biconvex nucleus (Bryan Cervical Disc® – Medtronic Sofamor Danek, Memphis, TN) can be associated with post-operative segmental kyphosis.

This study examines post-operative kyphosis and segmental imbalance following cervical disc replacement using the Bryan Cervical Disc prosthesis and factors which may influence this. In particular, the influence of change in disc space height as a result of surgery was studied.

Methods 67 patients underwent prosthetic disc replacement by one of three surgeons (19, 25 and 23 patients, respectively) using the Bryan prosthesis. 46 single, 20 double and 1 triple level were operated. Neutral pre- and post-op erect and intra-operative x-rays were examined manually and using digital image analysis software (Medical Metrics, Inc. Houston, TX). Possible contributing factors to segmental alignment were studied including: pre-op alignment, angle of prosthesis insertion, disc space degeneration and sacrifice of the posterior longitudinal ligament (PLL). Particular attention was given to changes in disc space height and factors which may influence this.

Inter- and intra-observer agreement was assessed. Non-parametric tests were used for assessment of categorical and skewed continuous variables. Multivariate linear regression was used to adjust significant correlation coefficients. Significance was set at p< 0.05.

Results The median pre-op focal lordosis of +0.5° (range: 21 to −14°, −ve = kyphotic) changed by −1° (+14 to −17°), to post-op: 0° (+11.5 to −16°).

There was a significant difference in the median change in focal lordosis for surgeon 1 (−3°) vs. surgeons 2 & 3 (−1°) (p< 0.005) and in the loss of disc space height. Median loss of disc space height for surgeon 1 was 22% vs. 8% for surgeons 2 & 3 (p< 0.002). Correlation co-efficient (Spearman) for change in disc space height vs. change in disc space angulation was 0.67 (p< 0.0001). No single pre- or intra-operative factor was found to clearly correlate with subsequent loss of disc space height apart from a trend towards a weak correlation with the angle of prosthesis insertion (r=0.24, p=0.06).

Discussion The median change (loss) in focal lordosis was −1.5° but there was considerable range: from +14° to −17°. Attempts to identify contributing factors suggest that a number may be involved but there did appear to be a highly significant correlation between loss of disc space height following surgery and subsequent focal kyphosis.

While the difference in outcomes between Surgeon 1 and Surgeons 2 & 3 is probably not clinically significant, it does suggest that intra-operative factors such as the angle of prosthesis insertion may be important. We are continuing to study these factors.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 305 - 305
1 Sep 2005
Duggal N Coolican M Parker D Giuffré B
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Introduction and Aims: Anterior cruciate ligament (ACL) injuries have historically been classified as non-contact or contact based on the mechanism of injury. The purpose of this study was to establish a detailed correlation between mechanism and the associated osteochondral, meniscal and other injuries to improve understanding of this common injury and its outcome.

Method: A descriptive analysis of prospectively collected data on ACL injuries requiring reconstruction between 2000 and 2004 was completed. Mechanism of injury was clearly elicited and correlated with clinical, radiologic and operative findings. Magnetic resonance imaging (MRI) was performed on all patients to analyse patterns of ACL rupture and associated osteochondral, meniscal and ligament injuries. Osteochondral injuries were analysed by a musculoskeletal radiologist according to location, intensity and depth. Intra-operative documentation of intra-articular injury pattern was also performed and correlated with MRI findings. Classification into ‘active’ (non-contact) and ‘passive’ (contact) mechanisms was completed and correlated with injury pattern.

Results: Seventy patients were identified with appropriate clinical, radiologic and operative data. A thorough review of the events surrounding the injury was documented. Forty-six patients described an active mechanism and 24 patients a passive mechanism of injury. Clinical examination demonstrated a similar proportion of medial collateral ligament injuries in each group. MRI within three months of injury demonstrated occult osteochondral lesions or ‘bone bruises’ in the majority of patients. Clear distinguishing patterns of femoral and tibial osteochondral injury were identified in the active and passive groups. Depth of osteochondral injury was most commonly classified as at least two-thirds the distance to the physeal scar in both groups. Intensity of the abnormal edema-like signal in the marrow of the distal femur and proximal tibia was most commonly classified as severe in both groups. Lateral meniscus injury was more common than medial, and was found in the majority of patients, more commonly in the passive group.

Conclusion: Although surgical techniques continue to improve, the ACL injury mechanism and its relation to intra-articular pathology is less well defined. This study defines either ‘active’ or ‘passive’ mechanisms, with implications for likely associated osteochondral and meniscal injury. This gives valuable insight into the ACL injured knee, its management, and eventual prognosis.