The primary endpoint of this study is to characterize the progression of bone defects at the femoral and tibial side in patients who sustained PJI of the knee that underwent two-stage revision with spacer implantation. In addition, we want to analyze the differences between functional moulded and hand-made spacers. A retrospective analysis of patients that underwent two-stage revision due to PJI of the knee between January 2014 and December 2021 at our institution. Diagnosis of infection was based on the criteria of the Muscoloskeletal Infection Society. The bone defect evaluation was performed intraoperatively based on the Aim
Methods
The aim of this study is to evaluate if the gentamycin elution from bone cement is influenced by the timing of application of the antibiotic powder. This was an experimental in vitro study that compared the elution properties of different formulation of gentamycin from a commercially available hip, knee and shoulder cement spacers. Four different experimental models were prepared. Five different spacers were prepared for each experimental mode and for each joint. We compared four different formulation of cement spacers: spacer #1, in which the spacer was prepared with a premixed bone-cement antibiotic mixture; spacer #2, in which the spacer was prepared by adding antibiotic powder to the bone cement at the time of spacer preparation; spacer #3, in which the spacer was prepared as spacer #2 but was stored for two months before starting the experiment; spacer #4, in addition to the gentamycin, other two antibiotics (tobramycin and vancomycin) were added to the bone cement. Gentamycin concentration was documented at seven intervals of time: T0 = 0h, T1 = 1h, T2 = 24h, T3 = 1W, T4 = 2W, T5 = 1M, T6 = 3M and T7 = 6M. The gentamycin elution at each interval of time was evaluated by using a T-student test.Aim
Method
Preoperative planning is a crucial step for total hip arthroplasty (THA), and 2D X-ray images are commonly used. The planning aims to provide the correct implant size, restore functional biomechanical conditions and avoid early complication such as dislocation, leg length discrepancy or abductors insufficiency. Limitations of 2D planning, besides the low accuracy in sizing, concerns the inability of planning the anteversion of both acetabular and femoral component on axial plane. Also, the verification of the planning intraoperatively is wholly left to qualitative measurements and the surgeon's experience. The need for having a more accurate and functional preoperative planning has been addressed using 3D models. The MyHip Planner (MHP) (Medacta International, Castel San Pietro, Switzerland), is a preoperative planning software which through artificial intelligent algorithm converts the CT scans into a 3D model that perfectly match the patient's anatomy. Then, automatic positioning of the implants is performed following the personal settings of the surgeon which will check and validate the planning, a personalized simulation of six daily activities to detect impingement of implants and bones. The MyHip Verifier (MHV) intraoperatively verifies the execution of the planning in terms of leg length and offset using two fluoroscopic images. Also, the size and cup angles can be calculated. The purpose of the present study was to validate the accuracy of the MHP [Fig 1] and MHV [Fig 2]. The dataset consisted of 13 patients who underwent primary uncemented THA. Each patient had a preoperative CT scan, intraoperative fluoroscopy, and postoperative CT scan after the surgery. The CT protocol used was low radiation (0,2 mm slicing for the pelvis, 0,5 mm for knees and ankles). The patients have been preoperatively planned used the MPH, and the accuracy of the components size prediction has been evaluated by comparing the preoperative planned values with the surgical reports. The MVH calculated the leg length and offset in terms of the difference between the preoperative and postoperative position of the femur concerning the pelvis. The accuracy of the measurements has been evaluated using postoperative CT scans. The MPH was able to predict the implanted size in 83% of the patient for the femoral stem and 96% for the acetabular component. The accuracy of the MVH in measuring the leg length was under 2 mm (1,6 ± 0,7 mm) while the offset was 2,5±1,6 mm. The cup angles were 5±1,1deg and 2,3±1,3deg for the anteversion and inclination, respectively. The average cup anteversion was 28,3°, mean cup inclination was 42,6°; femoral offset and leg length was restored in 96,5% of patients within a range of ±3 mm concerning the preoperative position. The results demonstrated the reliability of the MPH in predicting the implant size, and the accuracy of the MVH to verify the execution of the plan intraoperatively. The two software can be used in the clinical routine to improve the clinical outcome in THA. Limitations of this study are represented mainly by the small cohort of patients involved. For any figures or tables, please contact the authors directly.
Periprosthetic joint infections (PJI) are a severe complications after hip arthroplasty. The infections rate ranges from 0.7 to 1.3 depending on different reports. The aim of the present study is to evaluate the radiological and clinical outcome of patients that underwent two-stage revision for the treatment of periprosthetic joint infection of the hip when an extended trochanteric osteotomy (ETO) was necessary to remove the femoral stem. We retrospectively analyzed data from 84 patients that underwent two-stage revision of the hip between January 2006 and December 2010 at our institution. In forty-nine patients (Group A, 58.3%), the femoral stem was removed without an ETO, while in the remaining thirty-five patients (Group B, 41.7%) an ETO was necessary. In each case a metallic cerclage was used to closure of the flap. The average age for patients in group A was 64.3 years, while the average age in patients in group B was 66.4 years. The mean follow-up was respectively 117 months in group A and 122 months in group B. Eight patients died before the last follow-up, and data from six patients were incomplete. Complications, radiological and clinical outcome were. Mann Whitney U Test and Chi Square Test were used respectively to analyze continues and categorical variables. Cumulative survival of the implants was calculated for reinfection and mechanical complications with Kaplan-Meyer curves.Aim
Methods
