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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_5 | Pages 21 - 21
23 Apr 2024
Brown N King S Taylor M Foster P Harwood P
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Introduction

Traditionally, radiological union of fractures treated with an Ilizarov frame is confirmed by a period of dynamization - destabilisation of the frame for a period prior to removal. Reduced clinic availability during the COVID-19 pandemic caused a shift to selective dynamisation in our department, whereby lower risk patients had their frames removed on the same day as destabilisation. This study investigates the effects of this change in practice on outcomes and complication rates.

Materials & Methods

Adult patients treated with circular frames between April 2020 and February 2022 were identified from our Ilizarov database. Patients were divided into 2 groups: - “dynamised” if their frame was destabilised for a period to confirm union prior to removal; or “not dynamised” if the decision was taken to remove the frame without a period of dynamisation, other than a short period in the clinic. A retrospective review of clinical notes was conducted to determine outcome.


Bone & Joint Open
Vol. 4, Issue 11 | Pages 881 - 888
21 Nov 2023
Denyer S Eikani C Sheth M Schmitt D Brown N

Aims

The diagnosis of periprosthetic joint infection (PJI) can be challenging as the symptoms are similar to other conditions, and the markers used for diagnosis have limited sensitivity and specificity. Recent research has suggested using blood cell ratios, such as platelet-to-volume ratio (PVR) and platelet-to-lymphocyte ratio (PLR), to improve diagnostic accuracy. The aim of the study was to further validate the effectiveness of PVR and PLR in diagnosing PJI.

Methods

A retrospective review was conducted to assess the accuracy of different marker combinations for diagnosing chronic PJI. A total of 573 patients were included in the study, of which 124 knees and 122 hips had a diagnosis of chronic PJI. Complete blood count and synovial fluid analysis were collected. Recently published blood cell ratio cut-off points were applied to receiver operating characteristic curves for all markers and combinations. The area under the curve (AUC), sensitivity, specificity, and positive and negative predictive values were calculated.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 10 - 10
1 Jan 2018
Sheth N Melnic C Brown N Sporer S Paprosky W
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The treatment of severe acetabular bone loss is challenging, especially in the setting of an associated chronic pelvic discontinuity. There are several available treatment options for chronic pelvic discontinuity, each of which has its own disadvantages. One of the major difficulties with this entity, regardless of the reconstructive technique chosen, is the inability to obtain reproducible healing of the discontinuity. We evaluated the use of acetabular distraction, a technique which achieves peripheral or lateral distraction and central or medial compression across the discontinuity. We recommend acetabular distraction to allow for implantation of a stable construct, achieve biologic fixation and increase the likelihood of discontinuity healing.

In this multi-center trial, 32 patients that underwent acetabular revision for a chronic pelvic discontinuity using acetabular distraction were radiographically evaluated at a minimum of 25 months (range, 25 to 160 months). The study cohort was categorized according to the Paprosky acetabular bone loss classification: seven (22%) type IIC, five (16%) type IIIA, and 20 (62%) type IIIB defects. Fourteen (70%) of the 20 patients with a type IIIB acetabular bone loss pattern required use of augments for acetabular reconstruction.

Of the 32 patients, 1 (3%) patient required a revision for aseptic loosening, 2 (6%) patients had evidence of radiographic loosening but were not revised, and 3 (9%) patients had migration of the acetabular component into a more stable position. Radiographically, 22 (69%) of the cohort demonstrated healing of the discontinuity. The Kaplan-Meier construct survivorship was 83.3% when using aseptic acetabular loosening as an end-point.

During this study, the authors created a new pelvic discontinuity classification based on the type of reconstruction required. The classification mirrors the Paprosky acetabular bone loss classification. A Type I chronic pelvic discontinuity required jumbo cup reconstruction without augments. A type II discontinuity required the use of an augment for an extracavitary defect. A type III discontinuity required an augment for an intracavitary defect.

Type III defects were further subdivided into type IIIA and IIIB discontinuity. Type IIIA discontinuities utilized an augment to reconstruct the anterosuperior and/or posteroinferior column defect for primary stability of the overall construct. Type IIIB discontinuities utilized augments to reconstruct the anterosuperior and/or posteroinferior column defect for primary stability as well as a posterosuperior augment for supplemental fixation. All augments were unitized to the cup with cement. Type IV defects were massive defects that required the use of two orange-slice augments, secured together with screws and placed centrally to restore the defect, and a cup implanted and unitized to the augments with cement.

According to this new classification, the discontinuity reconstructions in our study were classified as follows: 12 (38%) type I, 8 (25%) type II, 6 (19%) type IIIA, 6 (19%) type IIIB, and 0 as type IV. Acetabular distraction technique demonstrates favorable radiographic outcomes with reproducible discontinuity healing in a majority of cases. This alternative technique allows for biologic fixation and intra-operative customization of the construct to be implanted based on the bone loss pattern present following component removal.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XL | Pages 172 - 172
1 Sep 2012
Sheth N Brown N Valle CD Berend M Berend K
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Introduction

This study compares the incidence of post-operative complications (within 90 days) following primary total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA).

Methods

2,919 Consecutive patients were retrospectively reviewed over 5 years at three institutions; 2,290 underwent primary TKA and 629 underwent UKA. Simultaneous bilateral procedures and diagnoses other than osteoarthritis were excluded. Regression analysis was performed to isolate the effects of TKA versus UKA on the rate of post-operative complications.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 27 - 27
1 Jun 2012
Cipriano C Brown N Valle CD Sporer S
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Introduction

Modular tapered implants have been suggested as the optimal treatment in patients with severe femoral bone loss undergoing revision total hip arthroplasty (THA). The purpose of this study is to describe minimum 2 year follow up of patients treated with modular tapered prostheses for Paprosky type IIIB and IV femoral bone loss in revision THA.

Methods

44 Consecutive patients with Paprosky type IIIB (23) or IV (21) femurs undergoing revision total hip arthroplasty to cementless modular tapered prostheses were studied. Harris Hip Scores were obtained prior to revision on all patients except those presenting with acute implant failure or periprosthetic fracture. 10 Patients were deceased within 2 years of surgery; the remaining 18 were followed for an average of 42 months (range 25-69 months). Clinical outcomes were measured using the Harris Hip Score, and radiographs were assessed for signs of stem loosening or subsidence >4mm.


INTRODUCTION

The purpose of this study was to determine the rate of complications and re-operations after operative treatment of peri-prosthetic femur fractures sustained within 90 days following primary total hip arthroplasty (THA).

METHODS

4,433 patients (5,196 consecutive primary THAs) over 10 years at a single institution were retrospectively reviewed. Thirty-five (0.67%) peri-prosthetic fractures that were treated operatively in 32 patients were identified and classified using the Vancouver Classification. There were 9 patients with a type Ag fracture, 2 patients with a type B1 fracture, 17 patients with a type B2 fracture, 1 patient with a type B3 fracture, and 3 patients with a concomitant type Ag and B2 fracture. Eleven (34%) patients were treated with isolated ORIF: greater trochanter (9) or femoral shaft (2). Twenty-one (66%) were treated with femoral revision combined with (14) or without (7) attempted fracture fragment reduction; a diaphseal engaging stem was utilized in all revisions. One patient was lost to follow-up leaving 31 patients for evaluation


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 28 - 28
1 Jun 2012
Cipriano C Brown N Jacofsky M Sporer S Valle CD
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Introduction

When using press-fit stems in revision total knee arthroplasty (TKA), diaphyseal engagement optimizes stability. Attempts to maximize press fit may lead to periprosthetic fracture; however, the literature offers no guidance regarding the prevalence or management of this complication. The purpose of this study is to report the incidence, risk factors, and outcomes of these fractures.

Methods

634 Stemmed implants (307 femoral and 327 tibial) from 413 consecutive revision TKAs were reviewed. Immediate and 6 week post-operative radiographs were examined. Patient age, gender, stem length, diameter, and offset were evaluated as potential risk factors for fracture occurrence using a paired t-test for continuous and a chi-square analysis for categorical variables.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 29 - 29
1 Jun 2012
Cipriano C Brown N Michael A Moric M Sporer S Valle CD
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Introduction

Serum erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), and synovial fluid white blood cell (WBC) count and differential are effective in diagnosing periprosthetic joint infection (PPJI); however their utility in patients with inflammatory arthritis is unknown. The purpose of this study is to determine the utility of these tests in patients with inflammatory arthritis.

Methods

934 Consecutive revision hip and knee arthroplasties were prospectively evaluated for PPJI. 202 Cases were excluded due to acute post-operative or hematogenous infection. 690 Patients had non-inflammatory and 42 had inflammatory arthritis. Receiver operating characteristic (ROC) curves were used to establish optimal ESR, CRP, WBC, and % neutrophil values for diagnosis of PPJI, and the area under the curve (AUC) was calculated to determine the overall accuracy.