Preoperative planning is a crucial step for total hip arthroplasty (THA), and 2D X-ray images are commonly used. The planning aims to provide the correct implant size, restore functional biomechanical conditions and avoid early complication such as dislocation, leg length discrepancy or abductors insufficiency. Limitations of 2D planning, besides the low accuracy in sizing, concerns the inability of planning the anteversion of both acetabular and femoral component on axial plane. Also, the verification of the planning intraoperatively is wholly left to qualitative measurements and the surgeon's experience. The need for having a more accurate and functional preoperative planning has been addressed using 3D models. The MyHip Planner (MHP) (Medacta International, Castel San Pietro, Switzerland), is a preoperative planning software which through artificial intelligent algorithm converts the CT scans into a 3D model that perfectly match the patient's anatomy. Then, automatic positioning of the implants is performed following the personal settings of the surgeon which will check and validate the planning, a personalized simulation of six daily activities to detect impingement of implants and bones. The MyHip Verifier (MHV) intraoperatively verifies the execution of the planning in terms of leg length and offset using two fluoroscopic images. Also, the size and cup angles can be calculated. The purpose of the present study was to validate the accuracy of the MHP [Fig 1] and MHV [Fig 2].

The dataset consisted of 13 patients who underwent primary uncemented THA. Each patient had a preoperative CT scan, intraoperative fluoroscopy, and postoperative CT scan after the surgery. The CT protocol used was low radiation (0,2 mm slicing for the pelvis, 0,5 mm for knees and ankles). The patients have been preoperatively planned used the MPH, and the accuracy of the components size prediction has been evaluated by comparing the preoperative planned values with the surgical reports. The MVH calculated the leg length and offset in terms of the difference between the preoperative and postoperative position of the femur concerning the pelvis. The accuracy of the measurements has been evaluated using postoperative CT scans. The MPH was able to predict the implanted size in 83% of the patient for the femoral stem and 96% for the acetabular component. The accuracy of the MVH in measuring the leg length was under 2 mm (1,6 ± 0,7 mm) while the offset was 2,5±1,6 mm. The cup angles were 5±1,1deg and 2,3±1,3deg for the anteversion and inclination, respectively. The average cup anteversion was 28,3°, mean cup inclination was 42,6°; femoral offset and leg length was restored in 96,5% of patients within a range of ±3 mm concerning the preoperative position. The results demonstrated the reliability of the MPH in predicting the implant size, and the accuracy of the MVH to verify the execution of the plan intraoperatively. The two software can be used in the clinical routine to improve the clinical outcome in THA. Limitations of this study are represented mainly by the small cohort of patients involved.

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Since its introduction in total hip replacements in the 1960's, Ultra High Molecular Weight Polyethylene (UHMWPE) has played a major role as a bearing component material for joint arthroplasty. Concerns were raised when issues of wear resistance became apparent, and therefore Highly Crosslinked Polyethylenes were introduced. Such materials undergo a thermal treatment to quench the free radicals and reduce progressive oxidation.

However, said thermal treatment weakens the material mechanical properties and hence the use of antioxidants has been proposed and implemented in clinical use, mainly Vitamin-E. This can be added to the material before or after irradiation. If it is done before, part of the anti-oxydant is consumed during irradiation and so will not be available for its main purpose, and part reacts before irradiation with the free radicals thus reducing the crosslinking effect. If it is added after irradiation, high temperatures are required in order to diffuse it in the bulk material, and anyway the surface will be mainly rich in antioxidant. However, Vitamin-E tends to neutralize the free radicals on the oxidized lipid chain present in our body fluids and so in direct contact with the prosthetic components: such mechanism reduces the Vitamin-E quantity available for anti-oxidation purposes in the long run.

A UHMWPE doped with Hindered Amine Light Stabilizer (HALS) has been developed and tested for applications in large joint replacements where highest resistance to wear and tough mechanical properties are simultaneously required, such as tibial inserts for knee joints or acetabular inserts for large diameter heads.

Mechanical and biocompatibility tests were run in accordance with ASTM F 2565-06 and ISO 10993-1 with successful results and good reproducibility.

In particular, electro spin resonance exhibited a very high level of free radicals in the three samples, which confirms the properties of this new material. Free radicals are the result of the activation of the HALS molecules during irradiation, creating nitroxide radicals that will destroy the residual alkyl radicals responsible for the oxidation before and after implantation.

Biocompatibility tests proved absence of cytotoxicity, sensitization, irritation, genotoxicity or pyrogenic reactions.

The possible future applications for this new material in the arthroplasty field will be discussed along with the expected advances and advantages.

Introduction

Patient-specific cutting guides entered into clinical practice few years ago, first introduced in total knee replacement and recently also for other joint replacements. Advantages claimed are improving accuracy and repeatability in implant placement. New patient-specific guides to perform an accurate femoral neck resection and provide a precise alignment reference for acetabular reaming in total hip arthroplasty (THA) were recently developed by Medacta International: MyHip Technology. To date femoral guides can be designed for both anterior and posterior approaches, whereas acetabular guides are available only for posterior approach.

Evaluation of the repeatability and reproducibility of MyHip guides placement on cadavers is performed using a navigation system. Accuracy of femoral MyHip guides is evaluated also through one author's clinical experience (RP).

Introduction

Conventional pre-operative planning for total hip arthroplasty mostly relies on the patient radiologic anatomy for the positioning and choice of implants. This kind of planning essentially remains a static approach since dynamic aspects such as the joint kinematics are not taken into account. Hence, clinicians are not able to fully consider the evolving behavior of the prosthetic joint that may lead to implant failures. In fact, kinematics plays an important role since some movement may create conflicts within the prosthetic joint and even provoke dislocations. The goal of our study was to assess the relationship between acetabular implant positioning variations and resultant impingements and loss of joint congruence during daily activities. In order to obtain accurate hip joint kinematics for simulation, we performed an in-vivo study using optical motion capture and magnetic resonance imaging (MRI).